Spotlight Archive

June 2024

Alexa Melucci, MD, PGY6

Research focus: My research focused on the outcomes of older adults with cancer after surgery. One project focused on the development of hospital acquired geriatric syndromes (malnutrition, delirium, etc.) after elective surgery for gastrointestinal cancer. We found older patients who undergo surgery for cancer are at risk for developing a syndrome in the hospital and development of the syndromes was associated with a higher risk of one-year mortality and significantly fewer days alive and out of hospital.

Read more: Alexa Melucci, MD

May 2024

Paul Burchard, MD, PGY3

Research focus: My research focused on targeting the highly treatment-resistant tumor microenvironment of cholangiocarcinoma by utilizing a novel agent that disrupts collagen-crosslinking to alter the tumor matrix. Through this project, we were able to reduce tumor stiffness and augment chemotherapeutic penetration to improve tumor control and survival in mouse models of cholangiocarcinoma.

Read more: Paul Burchard, MD