URMC / Urology / Research / Clinical Trials

Clinical Trials

Clinical trials are research studies that help doctors find new and better ways to prevent and treat diseases. Carefully conducted clinical trials are the most effective and safest way to find treatments that work. Search below to find clinical trials for urologic conditions currently being conducted at the University of Rochester Medical Center. Talk with your doctor to decide if a clinical trial is right for you.

For more information about the research or participation, please call our clinical trial help line at (585) 275-0126.

Current Active & Enrolling Studies

Prostate Studies

Study Name: Prospective, Multicenter, Single-Arm Study of Vanquish™ Water Vapor Ablation for Prostate Cancer (VAPOR 2 Study)
PI: Dr. Thomas Frye

Study Name: 4-aminopyridine Treatment for Nerve Injury from Radical Retro-Pubic Prostatectomy (4-AP)
PI: Dr. Thomas Osinski (ON HOLD)

Study Name: Scientific Consortium on Prostate Cancer Education (SCOPE) Registry (SCOPE)
PI: Dr. Jean Joseph

Bladder Studies

Study Name: A Novel Multiplex Elisa Assay for Evaluating Patients with Gross Hematuria for Bladder Cancer
PI: Dr. Edward Messing

Study Name: A Novel Multiplex Elisa Assay for Evaluating Patients with Microscopic Hematuria for Bladder Cancer
PI: Dr. Edward Messing

Study Name: A Phase 1b/2, Dose expansion, open-label study to evaluate safety and anti-tumor activity, of intravesical instillation of TARA-002 in adults with high-grade non-muscle invasive bladder cancer (Protara Ph 1b/2)
PI: Dr. William Tabayoyong

Study Name: A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG-Naïve High-Grade Non-Muscle Invasive Bladder Cancer (S1602)
PI: Dr. Edward Messing

Study Name: Pilot Study: Utilization of Optical Genome Mapping as a Diagnostic Screening Tool in Bladder Cancer (IQBAL study)
Co-PI: Dr. Anwar Iqbal and Dr. Thomas Frye

Kidney Studies

Study Name: Prospective Database for Evaluating Outcomes of Holmium Laser Enucleation of the Prostate (LEP)
PI: Dr. Jain

Study Name: Does Patient Self-Awareness of Intolerance of Uncertainty Improve Satisfaction with Decisions Regarding Management of Non-Obstructing Kidney Stones? (IUS)
PI: Dr. Jain

Study Name: S1931, “Phase III Trial of Immunotherapy-Based Combination Therapy with or Without Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma (Probe Trial)” Study Chairs: Drs. H.L. Kim and U.N. Vaishampayan (S1931)
PI: Dr. Thomas Frye

Study Name: The HistoSonics Edison™ System for treatment of primary solid renal tumors using histotripsy (Histosonics)
PI: Dr. Jean Joseph

Upcoming Trials

Check back soon for these upcoming trials to begin!

NMIBC Bladder cancer treatments for both high- and low-grade disease
Kidney Stone repository
Kidney Stone Treatment

Urology Clinical Trials Office

Austin Jackson, CCRC – Clinical Trials Manager

Austin Jackson has a B.S. in Kinesiology from SUNY Brockport. She is a certified clinical research coordinator (CCRC) through ACRP, the Association of Clinical Research Professionals. She has worked in healthcare for more than six years, with more than four of those years dedicated to Urology. She has been a research coordinator in Urology for three years and was recently promoted to a Sr. Clinical Research Coordinator role within the department. She is BLS certified and recently began a two year term on the Genesee Staff Council at the University of Rochester. Her primary research interests are urological diseases and disorders and men's health.

Grace Bennett, CRC

Grace Bennett is the newest addition to our team of research coordinators. She earned a Bachelor of Science in bioengineering from Clemson University in 2022, where she developed a strong foundation in problem-solving and data management. Grace is passionate about accessibility, having participated in projects at Clemson addressing inclusion in academics and disparities in healthcare, and aims to bring this perspective to our work. She is excited to begin her career back in her hometown of Rochester.

Natalie Carroll, CRC

Natalie Carroll grew up in Buffalo, NY, where she first developed her interest in urology working as a medical assistant at local clinic. She became a part of the urology team as a procedural technician in 2021 and was promoted to a clinical research coordinator after achieving her Bachelor of Science from the University at Buffalo. Her work in building trust with patients, addressing their concerns, and providing a supportive environment in clinical research has helped inform her future goal of earning her Bachelor of Science in Nursing. Beyond her professional pursuits, Natalie enjoys spending time with family (including those with paws) and tending to her plant collection.