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Deborah A. Slechta, Ph.D.

Deborah A. Slechta, Ph.D.

Connect with Deborah A. Slechta, Ph.D.

Environmental Health Sciences Center

Behavioral Sciences Facility

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About Me

Faculty Appointments

Professor - Department of Environmental Medicine (SMD)

Professor - Department of Neuroscience (SMD) - Joint

Professor - Department of Public Health Sciences (SMD) - Joint

Credentials

Post-doctoral Training & Residency

Postdoctoral Fellow, Behavioral Toxicology and Pharmacology, Department of Radiation Biology and Biophysics, University of Rochester. Advisors: Drs. Bernard Weiss and Victor G. Laties 1979 - 1982

Junior Staff Fellow, National Center for Toxicological Research, Jefferson, AR 1977 - 1979

Education

PhD | Univ Minnesota-Minneapolis. Psychology. 1977

MA | Western Michigan Univ. Psychology. 1972

BS | Western Michigan Univ. Psychology. 1971

Awards

Honoree, Fourth Annual Women in Science Symposium, Joint Programs of University of Medicine and Dentistry of New Jersey and Rutgers University, sponsored by The Environmental and Occupational Health Sciences Institute, Douglass College Project for Rutgers Women in Math, Science and Engineering, Joint Graduate Program in Toxicology, and the Joint Postdoctoral Program in Exposure Assessment, Piscataway, NJ 2001

National Institute of Environmental Health Sciences New Investigator Award 1982 - 1985

National Research Service Award Postdoctoral Fellowship 1979 - 1982

Alpha Lambda Delta, honorary sorority 1969

Research

Dr. Deborah Cory-Slechta became a faculty member at the University of Rochester Medical School (URMC) in 1982. She went on to become Chair of its Department of Environmental Medicine and Director of the NIEHS Environmental Health Sciences Center in 1998. She served as Dean for Research at the Univer...
Dr. Deborah Cory-Slechta became a faculty member at the University of Rochester Medical School (URMC) in 1982. She went on to become Chair of its Department of Environmental Medicine and Director of the NIEHS Environmental Health Sciences Center in 1998. She served as Dean for Research at the University of Rochester Medical School from 2000-2002. She then moved to NJ to become Director of the Environmental and Occupational Health Sciences Institute (EOHSI) and Chair of the Department of Environmental and Community Medicine at the UMDNJ-Robert Wood Johnson Medical School from 2003-2007, before returning to URMC as Professor in Environmental Medicine and Pediatrics. Dr. Cory-Slechta has served on numerous national review and advisory panels of the National Institutes of Health, the National Institute of Environmental Health Sciences, the Food and Drug Administration, the National Center for Toxicological Research, the Environmental Protection Agency, the National Academy of Sciences, the Institute of Medicine, and the Agency for Toxic Substances and Disease Registry, Centers for Disease Control. In addition, Dr. Cory-Slechta has served on the editorial boards of the journals Neurotoxicology, Toxicology, Toxicological Sciences, Fundamental and Applied Toxicology, Neurotoxicology and Teratology, and American Journal of Mental Retardation. She has held the elected positions of President of the Neurotoxicology Specialty Section of the Society of Toxicology, President of the Behavioral Toxicology Society, and been named a Fellow of the American Psychological Association. Her research has focused largely on the relationships between brain neurotransmitter systems and children's neurodevelopment, and how such relationships are altered by exposures to environmental toxicants, including the role played by environmental neurotoxicant exposures in developmental disabilities and neurodegenerative diseases. These research efforts have resulted in over 150 papers and book chapters to date.
Dr. Cory-Slechta is the co-director of the Behavioral Sciences Facility Core and director of the Animal Behavior Core which provides consultation and assistance to any investigators seeking to develop or implement a behavioral project aiming advance translational neurobehavioral research and enhance our understanding of human disease. The Behavioral Sciences Facility Core's mission is to advance the field of behavioral science by providing high quality services to scientists performing behavioral studies. Our ability to perform both animal and human behavioral testing allows us to work bi-directionally, applying lessons learned from animal work to human studies and vice versa. For this reason, our facility works on the cutting edge of translational behavioral research.
Dr. Cory-Slechta also directs the K12 WHEEL program at URMC. The Women's Health and the Environment Over the Entire Lifespan program provides career development for promising scientists interested in pursuing a research career in women's environmental health. Environmental exposures can affect males and females differently, often by acting on hormonal systems. These exposures appear to have greatest impact during critical periods across the lifespan (including prenatal, perinatal, childhood, mid-life and late-life).

Publications

Journal Articles

The contributions of neonatal inhalation of copper to air pollution-induced neurodevelopmental outcomes in mice.

Cubello J, Marvin E, Conrad K, Merrill AK, George JV, Welle K, Jackson BP, Chalupa D, Oberdörster G, Sobolewski M, Cory-Slechta DA

Neurotoxicology.. 2024 January 100 :55-71. Epub 12/09/2023.

Effects of mammary cancer and chemotherapy on neuroimmunological markers and memory function in a preclinical mouse model.

Netherby-Winslow C, Thompson B, Lotta L, Gallagher M, Van Haute P, Yang R, Hott D, Hasan H, Bachmann K, Bautista J, Gerber S, Cory-Slechta DA, Janelsins M

Brain, behavior, & immunity - health.. 2023 December 34 :100699. Epub 11/07/2023.

Cumulative Risk Evaluation of Phthalates Under TSCA.

Payne-Sturges D, De Saram S, Cory-Slechta DA

Environmental science & technology.. 2023 April 2557 (16):6403-6414. Epub 04/12/2023.

Making the invisible visible: Using a qualitative system dynamics model to map disparities in cumulative environmental stressors and children's neurodevelopment.

Payne-Sturges DC, Ballard E, Cory-Slechta DA, Thomas SB, Hovmand P

Environmental research.. 2023 March 15221 :115295. Epub 01/18/2023.

Neurotoxic effects of air pollution: an urgent public health concern.

Cory-Slechta DA, Sobolewski M

Nature reviews. Neuroscience.. 2023 March 24 (3):129-130. Epub 1900 01 01.

Air Pollution-Related Neurotoxicity Across the Life Span.

Cory-Slechta DA, Merrill A, Sobolewski M

Annual review of pharmacology and toxicology.. 2023 January 2063 :143-163. Epub 08/26/2022.

The potential involvement of inhaled iron (Fe) in the neurotoxic effects of ultrafine particulate matter air pollution exposure on brain development in mice.

Sobolewski M, Conrad K, Marvin E, Eckard M, Goeke CM, Merrill AK, Welle K, Jackson BP, Gelein R, Chalupa D, Oberdörster G, Cory-Slechta DA

Particle and fibre toxicology.. 2022 August 919 (1):56. Epub 08/09/2022.

Both parents matter: a national-scale analysis of parental race/ethnicity, disparities in prenatal PM exposures and related impacts on birth outcomes.

Payne-Sturges DC, Puett R, Cory-Slechta DA

Environmental health : a global access science source.. 2022 May 621 (1):47. Epub 05/06/2022.

Protracted Impairment of Maternal Metabolic Health in Mouse Dams Following Pregnancy Exposure to a Mixture of Low Dose Endocrine-Disrupting Chemicals, a Pilot Study.

Merrill AK, Anderson T, Conrad K, Marvin E, James-Todd T, Cory-Slechta DA, Sobolewski M

Toxics.. 2021 December 99 (12)Epub 12/09/2021.

Early Low-Level Arsenic Exposure Impacts Post-Synaptic Hippocampal Function in Juvenile Mice.

Foley KFW, Barnett D, Cory-Slechta DA, Xia H

Toxics.. 2021 August 319 (9)Epub 08/31/2021.

Confronting Racism in Environmental Health Sciences: Moving the Science Forward for Eliminating Racial Inequities.

Payne-Sturges DC, Gee GC, Cory-Slechta DA

Environmental health perspectives.. 2021 May 129 (5):55002. Epub 05/04/2021.

Defining and Intervening on Cumulative Environmental Neurodevelopmental Risks: Introducing a Complex Systems Approach.

Payne-Sturges DC, Cory-Slechta DA, Puett RC, Thomas SB, Hammond R, Hovmand PS

Environmental health perspectives.. 2021 March 129 (3):35001. Epub 03/10/2021.

Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-Specific Olfactory Impairment in Mice.

Anderson T, Merrill AK, Eckard ML, Marvin E, Conrad K, Welle K, Oberdörster G, Sobolewski M, Cory-Slechta DA

Toxicological sciences : an official journal of the Society of Toxicology.. 2021 February 26180 (1):175-185. Epub 1900 01 01.

Developmental exposure to methylmercury and resultant muscle mercury accumulation and adult motor deficits in mice.

Rand MD, Conrad K, Marvin E, Harvey K, Henderson D, Tawil R, Sobolewski M, Cory-Slechta DA

Neurotoxicology.. 2020 December 81 :1-10. Epub 07/28/2020.

Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease.

Hollander JA, Cory-Slechta DA, Jacka FN, Szabo ST, Guilarte TR, Bilbo SD, Mattingly CJ, Moy SS, Haroon E, Hornig M, Levin ED, Pletnikov MV, Zehr JL, McAllister KA, Dzierlenga AL, Garton AE, Lawler CP, Ladd-Acosta C

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.. 2020 June 45 (7):1086-1096. Epub 02/28/2020.

Lineage- and Sex-Dependent Behavioral and Biochemical Transgenerational Consequences of Developmental Exposure to Lead, Prenatal Stress, and Combined Lead and Prenatal Stress in Mice.

Sobolewski M, Abston K, Conrad K, Marvin E, Harvey K, Susiarjo M, Cory-Slechta DA

Environmental health perspectives.. 2020 February 128 (2):27001. Epub 02/05/2020.

Potential frameworks to support evaluation of mechanistic data for developmental neurotoxicity outcomes: A symposium report.

Carlson LM, Champagne FA, Cory-Slechta DA, Dishaw L, Faustman E, Mundy W, Segal D, Sobin C, Starkey C, Taylor M, Makris SL, Kraft A

Neurotoxicology and teratology.. 2020 78 :106865. Epub 02/14/2020.

The Impact of Inhaled Ambient Ultrafine Particulate Matter on Developing Brain: Potential Importance of Elemental Contaminants.

Cory-Slechta DA, Sobolewski M, Marvin E, Conrad K, Merrill A, Anderson T, Jackson BP, Oberdorster G

Toxicologic pathology.. 2019 December 47 (8):976-992. Epub 10/14/2019.

Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.

Jew K, Herr D, Wong C, Kennell A, Morris-Schaffer K, Oberdörster G, O'Banion MK, Cory-Slechta DA, Elder A

Particle and fibre toxicology.. 2019 November 2616 (1):45. Epub 11/26/2019.

Letter to the editor re: the CDC blood lead reference value for children.

Gottesfeld P, Cory-Slechta DA

Environmental health : a global access science source.. 2019 April 1118 (1):32. Epub 04/11/2019.

Healthy Air, Healthy Brains: Advancing Air Pollution Policy to Protect Children's Health.

Payne-Sturges DC, Marty MA, Perera F, Miller MD, Swanson M, Ellickson K, Cory-Slechta DA, Ritz B, Balmes J, Anderko L, Talbott EO, Gould R, Hertz-Picciotto I

American journal of public health.. 2019 April 109 (4):550-554. Epub 02/21/2019.

Effects of neonatal inhalation exposure to ultrafine carbon particles on pathology and behavioral outcomes in C57BL/6J mice.

Morris-Schaffer K, Merrill A, Jew K, Wong C, Conrad K, Harvey K, Marvin E, Sobolewski M, Oberdörster G, Elder A, Cory-Slechta DA

Particle and fibre toxicology.. 2019 February 1816 (1):10. Epub 02/18/2019.

Limited developmental neurotoxicity from neonatal inhalation exposure to diesel exhaust particles in C57BL/6 mice.

Morris-Schaffer K, Merrill AK, Wong C, Jew K, Sobolewski M, Cory-Slechta DA

Particle and fibre toxicology.. 2019 January 716 (1):1. Epub 01/07/2019.

Methods for Evaluating the Combined Effects of Chemical and Nonchemical Exposures for Cumulative Environmental Health Risk Assessment.

Clougherty JE, Linder S, Laumbach R, Carr Shmool JL, Symanski E, Cory-Slechta DA, Levy JI, Scammell MK, Payne-Sturges DC

International journal of environmental research and public health.. 2018 December 1015 (12)Epub 12/10/2018.

Developmental exposures to ultrafine particle air pollution reduces early testosterone levels and adult male social novelty preference: Risk for children's sex-biased neurobehavioral disorders.

Sobolewski M, Anderson T, Conrad K, Marvin E, Klocke C, Morris-Schaffer K, Allen JL, Cory-Slechta DA

Neurotoxicology.. 2018 September 68 :203-211. Epub 08/23/2018.

Enhanced cerebellar myelination with concomitant iron elevation and ultrastructural irregularities following prenatal exposure to ambient particulate matter in the mouse.

Klocke C, Sherina V, Graham UM, Gunderson J, Allen JL, Sobolewski M, Blum JL, Zelikoff JT, Cory-Slechta DA

Inhalation toxicology.. 2018 August 30 (9-10):381-396. Epub 12/20/2018.

Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice.

Morris-Schaffer K, Sobolewski M, Allen JL, Marvin E, Yee M, Arora M, O'Reilly MA, Cory-Slechta DA

Neurotoxicology.. 2018 July 67 :234-244. Epub 06/18/2018.

Developmental Lead Exposure and Prenatal Stress Result in Sex-Specific Reprograming of Adult Stress Physiology and Epigenetic Profiles in Brain.

Sobolewski M, Varma G, Adams B, Anderson DW, Schneider JS, Cory-Slechta DA

Toxicological sciences : an official journal of the Society of Toxicology.. 2018 June 1163 (2):478-489. Epub 1900 01 01.

Endocrine active metals, prenatal stress and enhanced neurobehavioral disruption.

Sobolewski M, Conrad K, Marvin E, Allen JL, Cory-Slechta DA

Hormones and behavior.. 2018 May 101 :36-49. Epub 02/01/2018.

Elemental mercury neurotoxicity and clinical recovery of function: A review of findings, and implications for occupational health.

Calabrese EJ, Iavicoli I, Calabrese V, Cory-Slechta DA, Giordano J

Environmental research.. 2018 May 163 :134-148. Epub 02/22/2018.

Analysis of Nonlinear Associations between Prenatal Methylmercury Exposure from Fish Consumption and Neurodevelopmental Outcomes in the Seychelles Main Cohort at 17 Years.

Huang LS, Cory-Slechta DA, Cox C, Thurston SW, Shamlaye CF, Watson GE, van Wijngaarden E, Zareba G, Strain JJ, Myers GJ, Davidson PW

Stochastic environmental research and risk assessment : research journal.. 2018 April 32 (4):893-904. Epub 09/06/2017.

Exposure to fine and ultrafine particulate matter during gestation alters postnatal oligodendrocyte maturation, proliferation capacity, and myelination.

Klocke C, Allen JL, Sobolewski M, Blum JL, Zelikoff JT, Cory-Slechta DA

Neurotoxicology.. 2018 March 65 :196-206. Epub 10/24/2017.

Associations between inflammatory markers and cognitive function in breast cancer patients receiving chemotherapy.

Williams AM, Shah R, Shayne M, Huston AJ, Krebs M, Murray N, Thompson BD, Doyle K, Korotkin J, van Wijngaarden E, Hyland S, Moynihan JA, Cory-Slechta DA, Janelsins MC

Journal of neuroimmunology.. 2018 January 15314 :17-23. Epub 10/18/2017.

Sex-Dependent Effects of Developmental Lead Exposure on the Brain.

Singh G, Singh V, Sobolewski M, Cory-Slechta DA, Schneider JS

Frontiers in genetics.. 2018 9 :89. Epub 03/16/2018.

Different Behavioral Experiences Produce Distinctive Parallel Changes in, and Correlate With, Frontal Cortex and Hippocampal Global Post-translational Histone Levels.

Sobolewski M, Singh G, Schneider JS, Cory-Slechta DA

Frontiers in integrative neuroscience.. 2018 12 :29. Epub 07/19/2018.

Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles.

Morris-Schaffer K, Sobolewski M, Welle K, Conrad K, Yee M, O'Reilly MA, Cory-Slechta DA

Neurotoxicology and teratology.. 2018 70 :51-59. Epub 10/11/2018.

Lung-Specific Extracellular Superoxide Dismutase Improves Cognition of Adult Mice Exposed to Neonatal Hyperoxia.

Buczynski BW, Mai N, Yee M, Allen JL, Prifti L, Cory-Slechta DA, Halterman MW, O'Reilly MA

Frontiers in medicine.. 2018 5 :334. Epub 12/10/2018.

Developmental Lead and/or Prenatal Stress Exposures Followed by Different Types of Behavioral Experience Result in the Divergence of Brain Epigenetic Profiles in a Sex, Brain Region, and Time-Dependent Manner: Implications for Neurotoxicology.

Cory-Slechta DA, Sobolewski M, Varma G, Schneider JS

Current opinion in toxicology.. 2017 October 6 :60-70. Epub 09/28/2017.

Neuropathological Consequences of Gestational Exposure to Concentrated Ambient Fine and Ultrafine Particles in the Mouse.

Klocke C, Allen JL, Sobolewski M, Mayer-Pröschel M, Blum JL, Lauterstein D, Zelikoff JT, Cory-Slechta DA

Toxicological sciences : an official journal of the Society of Toxicology.. 2017 April 1156 (2):492-508. Epub 1900 01 01.

Methyl mercury exposure and neurodevelopmental outcomes in the Seychelles Child Development Study Main cohort at age 22 and 24years.

van Wijngaarden E, Thurston SW, Myers GJ, Harrington D, Cory-Slechta DA, Strain JJ, Watson GE, Zareba G, Love T, Henderson J, Shamlaye CF, Davidson PW

Neurotoxicology and teratology.. 2017 59 :35-42. Epub 10/28/2016.

Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice.

Beier EE, Sheu TJ, Resseguie EA, Takahata M, Awad HA, Cory-Slechta DA, Puzas JE

Bone research.. 2017 5 :17013. Epub 05/09/2017.

A clinically relevant dose of cyclophosphamide chemotherapy impairs memory performance on the delayed spatial alternation task that is sustained over time as mice age.

Janelsins MC, Heckler CE, Thompson BD, Gross RA, Opanashuk LA, Cory-Slechta DA

Neurotoxicology.. 2016 September 56 :287-293. Epub 06/28/2016.

Project TENDR: Targeting Environmental Neuro-Developmental Risks The TENDR Consensus Statement.

Bennett D, Bellinger DC, Birnbaum LS, Bradman A, Chen A, Cory-Slechta DA, Engel SM, Fallin MD, Halladay A, Hauser R, Hertz-Picciotto I, Kwiatkowski CF, Lanphear BP, Marquez E, Marty M, McPartland J, Newschaffer CJ, Payne-Sturges D, Patisaul HB, Perera FP, Ritz B, Sass J, Schantz SL, Webster TF, Whyatt RM, Woodruff TJ, Zoeller RT, Anderko L, Campbell C, Conry JA, DeNicola N, Gould RM, Hirtz D, Huffling K, Landrigan PJ, Lavin A, Miller M, Mitchell MA, Rubin L, Schettler T, Tran HL, Acosta A, Brody C, Miller E, Miller P, Swanson M, Witherspoon NO, , , , , , , , ,

Environmental health perspectives.. 2016 July 1124 (7):A118-22. Epub 1900 01 01.

Sex-dependent effects of lead and prenatal stress on post-translational histone modifications in frontal cortex and hippocampus in the early postnatal brain.

Schneider JS, Anderson DW, Kidd SK, Sobolewski M, Cory-Slechta DA

Neurotoxicology.. 2016 May 54 :65-71. Epub 03/24/2016.

Unmasking silent neurotoxicity following developmental exposure to environmental toxicants.

Kraft AD, Aschner M, Cory-Slechta DA, Bilbo SD, Caudle WM, Makris SL

Neurotoxicology and teratology.. 2016 55 :38-44. Epub 04/02/2016.

A novel, ecologically relevant, highly preferred, and non-invasive means of oral substance administration for rodents.

Sobolewski M, Allen JL, Morris-Schaffer K, Klocke C, Conrad K, Cory-Slechta DA

Neurotoxicology and teratology.. 2016 56 :75-80. Epub 04/14/2016.

Engaging Communities in Research on Cumulative Risk and Social Stress-Environment Interactions: Lessons Learned from EPA's STAR Program.

Payne-Sturges DC, Korfmacher KS, Cory-Slechta DA, Jimenez M, Symanski E, Carr Shmool JL, Dotson-Newman O, Clougherty JE, French R, Levy JI, Laumbach R, Rodgers K, Bongiovanni R, Scammell MK

Environmental justice.. 2015 December 18 (6):203-212. Epub 1900 01 01.

Characterization of binge-dosed methamphetamine-induced neurotoxicity and neuroinflammation.

McConnell SE, O'Banion MK, Cory-Slechta DA, Olschowka JA, Opanashuk LA

Neurotoxicology.. 2015 September 50 :131-41. Epub 08/15/2015.

Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder.

Richardson JR, Taylor MM, Shalat SL, Guillot TS, Caudle WM, Hossain MM, Mathews TA, Jones SR, Cory-Slechta DA, Miller GW

FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2015 May 29 (5):1960-72. Epub 01/28/2015.

Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals.

Sobolewski M, Conrad K, Allen JL, Weston H, Martin K, Lawrence BP, Cory-Slechta DA

Neurotoxicology.. 2014 December 45 :121-30. Epub 10/22/2014.

Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice.

Allen JL, Liu X, Pelkowski S, Palmer B, Conrad K, Oberdörster G, Weston D, Mayer-Pröschel M, Cory-Slechta DA

Environmental health perspectives.. 2014 September 122 (9):939-45. Epub 06/05/2014.

Sex-dependent impacts of low-level lead exposure and prenatal stress on impulsive choice behavior and associated biochemical and neurochemical manifestations.

Weston HI, Weston DD, Allen JL, Cory-Slechta DA

Neurotoxicology.. 2014 September 44 :169-83. Epub 07/07/2014.

Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation.

Allen JL, Liu X, Weston D, Prince L, Oberdörster G, Finkelstein JN, Johnston CJ, Cory-Slechta DA

Toxicological sciences : an official journal of the Society of Toxicology.. 2014 July 140 (1):160-78. Epub 04/01/2014.

Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice.

Allen JL, Liu X, Weston D, Conrad K, Oberdörster G, Cory-Slechta DA

Neurotoxicology.. 2014 March 41 :80-8. Epub 01/30/2014.

Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress.

Weston HI, Sobolewski M, Allen JL, Weston D, Conrad K, Pelkowski S, Watson GE, Zareba G, Cory-Slechta DA

Neurotoxicology.. 2014 March 41 :123-40. Epub 02/03/2014.

Depressive symptoms are associated with allostatic load among community-dwelling older adults.

Kobrosly RW, van Wijngaarden E, Seplaki CL, Cory-Slechta DA, Moynihan J

Physiology & behavior.. 2014 January 17123 :223-30. Epub 1900 01 01.

Early-stage primary school children attending a school in the Malawian School Feeding Program (SFP) have better reversal learning and lean muscle mass growth than those attending a non-SFP school.

Nkhoma OW, Duffy ME, Cory-Slechta DA, Davidson PW, McSorley EM, Strain JJ, O'Brien GM

The Journal of nutrition.. 2013 August 143 (8):1324-30. Epub 06/26/2013.

Multisystem physiological dysfunction is associated with depressive symptoms in a population-based sample of older adults.

Kobrosly RW, Seplaki CL, Cory-Slechta DA, Moynihan J, van Wijngaarden E

International journal of geriatric psychiatry.. 2013 July 28 (7):718-27. Epub 09/07/2012.

Blood pressure and cognitive function: a prospective analysis among adolescents in Seychelles.

Lyngdoh T, Viswanathan B, Kobrosly R, van Wijngaarden E, Huber B, Davidson PW, Cory-Slechta DA, Strain S, Myers GJ, Bovet P

Journal of hypertension.. 2013 June 31 (6):1175-82. Epub 1900 01 01.

Health risks from lead-based ammunition in the environment.

Bellinger DC, Burger J, Cade TJ, Cory-Slechta DA, Finkelstein M, Hu H, Kosnett M, Landrigan PJ, Lanphear B, Pokras MA, Redig PT, Rideout BA, Silbergeld E, Wright R, Smith DR

Environmental health perspectives.. 2013 June 121 (6):A178-9. Epub 1900 01 01.

Nutritional and cognitive status of entry-level primary school children in Zomba, rural Malawi.

Nkhoma OW, Duffy ME, Davidson PW, Cory-Slechta DA, McSorley EM, Strain JJ, O'Brien GM

International journal of food sciences and nutrition.. 2013 May 64 (3):282-91. Epub 11/23/2012.

Brain hemispheric differences in the neurochemical effects of lead, prenatal stress, and the combination and their amelioration by behavioral experience.

Cory-Slechta DA, Weston D, Liu S, Allen JL

Toxicological sciences : an official journal of the Society of Toxicology.. 2013 April 132 (2):419-30. Epub 01/28/2013.

Variations in the nature of behavioral experience can differentially alter the consequences of developmental exposures to lead, prenatal stress, and the combination.

Cory-Slechta DA, Merchant-Borna K, Allen JL, Liu S, Weston D, Conrad K

Toxicological sciences : an official journal of the Society of Toxicology.. 2013 January 131 (1):194-205. Epub 08/28/2012.

Developmental exposure to concentrated ambient particles and preference for immediate reward in mice.

Allen JL, Conrad K, Oberdörster G, Sleezer B, Cory-Slechta DA

Environmental health perspectives.. 2013 January 121 (1):32-8. Epub 10/11/2012.

Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling.

Beier EE, Maher JR, Sheu TJ, Cory-Slechta DA, Berger AJ, Zuscik MJ, Puzas JE

Environmental health perspectives.. 2013 January 121 (1):97-104. Epub 10/19/2012.

Maternal PUFA status but not prenatal methylmercury exposure is associated with children's language functions at age five years in the Seychelles.

Strain JJ, Davidson PW, Thurston SW, Harrington D, Mulhern MS, McAfee AJ, van Wijngaarden E, Shamlaye CF, Henderson J, Watson GE, Zareba G, Cory-Slechta DA, Lynch M, Wallace JM, McSorley EM, Bonham MP, Stokes-Riner A, Sloane-Reeves J, Janciuras J, Wong R, Clarkson TW, Myers GJ

The Journal of nutrition.. 2012 November 142 (11):1943-9. Epub 09/26/2012.

The outdoor air pollution and brain health workshop.

Block ML, Elder A, Auten RL, Bilbo SD, Chen H, Chen JC, Cory-Slechta DA, Costa D, Diaz-Sanchez D, Dorman DC, Gold DR, Gray K, Jeng HA, Kaufman JD, Kleinman MT, Kirshner A, Lawler C, Miller DS, Nadadur SS, Ritz B, Semmens EO, Tonelli LH, Veronesi B, Wright RO, Wright RJ

Neurotoxicology.. 2012 October 33 (5):972-84. Epub 09/05/2012.

Subchronic polychlorinated biphenyl (Aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems.

Lee DW, Notter SA, Thiruchelvam M, Dever DP, Fitzpatrick R, Kostyniak PJ, Cory-Slechta DA, Opanashuk LA

Toxicological sciences : an official journal of the Society of Toxicology.. 2012 February 125 (2):496-508. Epub 11/17/2011.

Increased lead biomarker levels are associated with changes in hormonal response to stress in occupationally exposed male participants.

Fortin MC, Cory-Slechta DA, Ohman-Strickland P, Nwankwo C, Yanger TS, Todd AC, Moynihan J, Walton J, Brooks A, Fiedler N

Environmental health perspectives.. 2012 February 120 (2):278-83. Epub 11/23/2011.

Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development study.

Davidson PW, Cory-Slechta DA, Thurston SW, Huang LS, Shamlaye CF, Gunzler D, Watson G, van Wijngaarden E, Zareba G, Klein JD, Clarkson TW, Strain JJ, Myers GJ

Neurotoxicology.. 2011 December 32 (6):711-7. Epub 08/25/2011.

Blood lead levels in relation to cognitive function in older U.S. adults.

van Wijngaarden E, Winters PC, Cory-Slechta DA

Neurotoxicology.. 2011 January 32 (1):110-5. Epub 11/17/2010.

Socioeconomic position and cognitive function in the Seychelles: a life course analysis.

Kobrosly RW, van Wijngaarden E, Galea S, Cory-Slechta DA, Love T, Hong C, Shamlaye CF, Davidson PW

Neuroepidemiology.. 2011 36 (3):162-8. Epub 04/20/2011.

Enhanced learning deficits in female rats following lifetime pb exposure combined with prenatal stress.

Cory-Slechta DA, Stern S, Weston D, Allen JL, Liu S

Toxicological sciences : an official journal of the Society of Toxicology.. 2010 October 117 (2):427-38. Epub 07/16/2010.

Bone lead levels are associated with measures of memory impairment in older adults.

van Wijngaarden E, Campbell JR, Cory-Slechta DA

Neurotoxicology.. 2009 July 30 (4):572-80. Epub 05/27/2009.

The conundrum of unmeasured confounding: Comment on: "Can some of the detrimental neurodevelopmental effects attributed to lead be due to pesticides? by Brian Gulson".

Lanphear BP, Hornung RW, Khoury J, Dietrich KN, Cory-Slechta DA, Canfield RL

The Science of the total environment.. 2008 June 25396 (2-3):196-200. Epub 03/07/2008.

Letter regarding: "Paraquat: the red herring of Parkinson's disease research".

Cory-Slechta DA, Thiruchelvam M, Di Monte DA

Toxicological sciences : an official journal of the Society of Toxicology.. 2008 May 103 (1):215-6; author reply 217-8. Epub 12/27/2007.

Lifetime consequences of combined maternal lead and stress.

Cory-Slechta DA, Virgolini MB, Rossi-George A, Thiruchelvam M, Lisek R, Weston D

Basic & clinical pharmacology & toxicology.. 2008 February 102 (2):218-27. Epub 1900 01 01.

Blood lead concentrations < 10 microg/dL and child intelligence at 6 years of age.

Jusko TA, Henderson CR, Lanphear BP, Cory-Slechta DA, Parsons PJ, Canfield RL

Environmental health perspectives.. 2008 February 116 (2):243-8. Epub 1900 01 01.

Interactive effects of a DRD4 polymorphism, lead, and sex on executive functions in children.

Froehlich TE, Lanphear BP, Dietrich KN, Cory-Slechta DA, Wang N, Kahn RS

Biological psychiatry.. 2007 August 162 (3):243-9. Epub 01/17/2007.

Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase.

Gray JP, Heck DE, Mishin V, Smith PJ, Hong JY, Thiruchelvam M, Cory-Slechta DA, Laskin DL, Laskin JD

The Journal of biological chemistry.. 2007 March 16282 (11):7939-49. Epub 01/17/2007.

The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder.

Barlow BK, Cory-Slechta DA, Richfield EK, Thiruchelvam M

Reproductive toxicology.. 2007 23 (3):457-70. Epub 02/06/2007.

Development and validation of a test battery to assess subtle neurodevelopmental differences in children.

Davidson PW, Weiss B, Beck C, Cory-Slechta DA, Orlando M, Loiselle D, Young EC, Sloane-Reeves J, Myers GJ

Neurotoxicology.. 2006 December 27 (6):951-69. Epub 04/28/2006.

Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function.

Virgolini MB, Chen K, Weston DD, Bauter MR, Cory-Slechta DA

Toxicological sciences : an official journal of the Society of Toxicology.. 2005 October 87 (2):469-82. Epub 07/27/2005.

Developmental pesticide models of the Parkinson disease phenotype.

Cory-Slechta DA, Thiruchelvam M, Barlow BK, Richfield EK

Environmental health perspectives.. 2005 September 113 (9):1263-70. Epub 1900 01 01.

Studying toxicants as single chemicals: does this strategy adequately identify neurotoxic risk?

Cory-Slechta DA

Neurotoxicology.. 2005 August 26 (4):491-510. Epub 1900 01 01.

[WITHDRAWN] Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype.

Thiruchelvam M, Prokopenko O, Cory-Slechta DA, Richfield EK, Buckley B, Mirochnitchenko O

The Journal of biological chemistry.. 2005 June 10280 (23):22530-9. Epub 04/11/2005.

Sustained exposure to the widely used herbicide atrazine: altered function and loss of neurons in brain monoamine systems.

Rodriguez VM, Thiruchelvam M, Cory-Slechta DA

Environmental health perspectives.. 2005 June 113 (6):708-15. Epub 1900 01 01.

Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency.

Carmouche JJ, Puzas JE, Zhang X, Tiyapatanaputi P, Cory-Slechta DA, Gelein R, Zuscik M, Rosier RN, Boyce BF, O'Keefe RJ, Schwarz EM

Environmental health perspectives.. 2005 June 113 (6):749-55. Epub 1900 01 01.

Developmental pesticide exposures and the Parkinson's disease phenotype.

Cory-Slechta DA, Thiruchelvam M, Richfield EK, Barlow BK, Brooks AI

Birth defects research. Part A, Clinical and molecular teratology.. 2005 March 73 (3):136-9. Epub 1900 01 01.

Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells.

Barlow BK, Lee DW, Cory-Slechta DA, Opanashuk LA

Neurotoxicology.. 2005 January 26 (1):63-75. Epub 1900 01 01.

The effect of developmental exposure to the fungicide triadimefon on behavioral sensitization to triadimefon during adulthood.

Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA

Toxicology and applied pharmacology.. 2004 October 1200 (1):54-63. Epub 1900 01 01.

Maternal stress modulates the effects of developmental lead exposure.

Cory-Slechta DA, Virgolini MB, Thiruchelvam M, Weston DD, Bauter MR

Environmental health perspectives.. 2004 May 112 (6):717-30. Epub 1900 01 01.

Impaired neuropsychological functioning in lead-exposed children.

Canfield RL, Gendle MH, Cory-Slechta DA

Developmental neuropsychology.. 2004 26 (1):513-40. Epub 1900 01 01.

A fetal risk factor for Parkinson's disease.

Barlow BK, Richfield EK, Cory-Slechta DA, Thiruchelvam M

Developmental neuroscience.. 2004 26 (1):11-23. Epub 1900 01 01.

Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon.

Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA

Pharmacology, biochemistry, and behavior.. 2003 September 76 (2):315-26. Epub 1900 01 01.

Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype.

Thiruchelvam M, McCormack A, Richfield EK, Baggs RB, Tank AW, Di Monte DA, Cory-Slechta DA

The European journal of neuroscience.. 2003 August 18 (3):589-600. Epub 1900 01 01.

Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates.

Barlow BK, Thiruchelvam MJ, Bennice L, Cory-Slechta DA, Ballatori N, Richfield EK

Journal of neurochemistry.. 2003 May 85 (4):1075-86. Epub 1900 01 01.

Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter.

Canfield RL, Henderson CR, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP

The New England journal of medicine.. 2003 April 17348 (16):1517-26. Epub 1900 01 01.

Lead-induced impairments in complex cognitive function: offerings from experimental studies.

Cory-Slechta DA

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.. 2003 March 9 (1):54-75. Epub 1900 01 01.

Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype.

Thiruchelvam M, Richfield EK, Goodman BM, Baggs RB, Cory-Slechta DA

Neurotoxicology.. 2002 October 23 (4-5):621-33. Epub 1900 01 01.

Lead exposure and dorsomedial striatum mediation of fixed interval schedule-controlled behavior.

Cory-Slechta DA, Brockel BJ, O'Mara DJ

Neurotoxicology.. 2002 September 23 (3):313-27. Epub 1900 01 01.

Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat.

McCormack AL, Thiruchelvam M, Manning-Bog AB, Thiffault C, Langston JW, Cory-Slechta DA, Di Monte DA

Neurobiology of disease.. 2002 July 10 (2):119-27. Epub 1900 01 01.

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.

Richfield EK, Thiruchelvam MJ, Cory-Slechta DA, Wuertzer C, Gainetdinov RR, Caron MG, Di Monte DA, Federoff HJ

Experimental neurology.. 2002 May 175 (1):35-48. Epub 1900 01 01.

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors.

Brooks AI, Stein CS, Hughes SM, Heth J, McCray PM, Sauter SL, Johnston JC, Cory-Slechta DA, Federoff HJ, Davidson BL

Proceedings of the National Academy of Sciences of the United States of America.. 2002 April 3099 (9):6216-21. Epub 04/16/2002.