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Gloria Pryhuber, M.D.

Gloria Pryhuber, M.D.

Pediatrics , Neonatology

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UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
Accepting New Patients

Contact

Office (585) 275-2972
Fax (585) 461-3614

About Me

Acute and Chronic Lung Disease in Neonates
Acute and Chronic Lung Disease in Neonates

Certified Specialties

Neonatal-Perinatal Medicine - American Board of Pediatrics

Faculty Appointments

Professor - Department of Pediatrics, Neonatology (SMD)

Credentials

Residency & Fellowship

Fellowship, Fellow, University of Cincinnati College of Medicine. 1988 - 1991

Residency, Resident, University Hospital-SUNY Health Science Center. 1986 - 1988

Internship, Pediatrics, University Hospital-SUNY Health Science Center. 1985 - 1986

Education

MD | SUNY Upstate College of Health Professions. 1985

Awards

Ruth A. Lawrence Academic Faculty Service Award for Excellence in Research. 2014

American Pediatric Society Membe. 2013

George Washington Goler Professor of Pediatrics. 2011 - 2014

Perinatal Research Society Member. 2011

Best Doctors in America Database. 2006

Ruth A. Lawrence Academic Faculty Service Award for Excellence in Training, Department of Pediatrics, University of Rochester, R. 2005

University of Rochester Environmental Health Sciences Center, Pulmonary Core - Member. 2001

Society for Pediatric Research - Member. 1999

Buswell Fellowship Award University of Rochester. 1995

Chief Fellow in Neonatology, University of Cincinnati, Cincinnati, OH. 1989

Resident Teaching Award. 1986 - 1987

Resident Teaching Award. 1985 - 1986

Janet M. Glascow Memorial Achievement Award. 1985

Alpha Omega Alpha Medical Honor Society. 1985

Annual Clinical Campus Pediatric Award. 1984

Cornell University, College Honor Society. 1978 - 1981

Research

Research interests:
1) Chronic Lung Disease of Prematurity
2) Lung Development

Dr. Pryhuber trained as a post-doctoral Proctor Research Scholar and participant in the University of Cincinnati Program of Excellence in Molecular Biology of the Heart and Lung. She has since accumulated > ...
Research interests:
1) Chronic Lung Disease of Prematurity
2) Lung Development

Dr. Pryhuber trained as a post-doctoral Proctor Research Scholar and participant in the University of Cincinnati Program of Excellence in Molecular Biology of the Heart and Lung. She has since accumulated > 20 years as independent researcher and author in lung injury and immunology. She serves on NIH study sections and as reviewer for journals in her area of expertise, manages an active laboratory, supervises students in pulmonary biology and epithelial cell research and has received awards recognizing both teaching and original research accomplishments. She teaches regularly for the UofR Toxicology graduate program, Medical School and Pediatric Residency.

An NIH-funded physician-scientist with expertise in human perinatal lung injury and repair, Dr. Pryhuber also served nine years as Perinatal-Neonatal Fellowship Associate Director and mentors undergraduate, graduate and post-doctoral students. She is honored to be a member of the American Pediatric Society, the Perinatal Research Society, and the Society for Pediatric Research, the American Thoracic Society, the American Academy of Pediatrics, the International Cytokine Society and the American Physiological Society. As Professor in the Departments of Pediatrics and Environmental Medicine, Dr. Pryhuber also acts as communicating PI for the UofR / University at Buffalo Center for the Prematurity and Respiratory Outcomes Program (PROP, NHLBI U01), as Lead Site Investigator for the UR-Respiratory Pathogens Research Center Clinical Study I (NIAID / DMID Contract), PI for the Lung Molecular Atlas Program Human Tissue Core (NHLBI U01) and remains active as clinical academic Neonatologist and Pulmonary Hypertension Team member. Dr. Pryhuber directs the UofR Pediatric and Environmental Health Sciences Center Histology Facility since 2009 and Pediatric Processing Lab since 2011, providing, through the work of talented technicians and University resources, technical support and training for preparation and analysis of tissues and cells of organisms ranging from human to drosophila. Dr. Pryhuber has also provided access to an archive of neonatal lung tissue acquired by expedited autopsy at gestational ages varying from 24 to 43 weeks. In collaboration with investigators in multiple centers, subsets of the archive are published, contributing novel observations pertaining to vascular development, epithelial cell abnormalities and inflammation in bronchopulmonary dysplasia. This repository is expanded by the LungMAP to collect donated human lung across the developmental spectrum from pseudoglandular through alveologenesis. These successful clinical and research programs demonstrate particular interests and strengths in creating multi-disciplinary teams of investigators, coordinators, nurses, technicians, and information specialists. They create and foster active collaborations of investigators and clinicians in neonatology, pulmonology, infectious disease, obstetrics/perinatology, immunology, microbiology, pathology, toxicology and genomics, as well as extramural collaborations around perinatal development and disease.

Clinically, preterm infant cohorts are enrolled in longitudinal studies. In the laboratory, fresh isolated cells, cell lines and whole animal models are utilized to understand cellular interactions during development and inflammation. Specific studies determined parenchymal TNF receptor signaling mechanisms that regulate gene expression, inflammation and apoptosis in the lung. More recently, high-dimensional flow cytometry, cell sorting, transcriptomic and genomic techniques are applied to understand the effects of in utero environment, premature birth and microbial colonization on the adaptive immune system and lung. The impact on respiratory morbidity and mortality of alterations in CD4 and CD8 lymphocyte responses to stimuli are the focus of active studies.

Research Lab

Publications

Journal Articles

scDOT: optimal transport for mapping senescent cells in spatial transcriptomics.

Nguyen ND, Rosas L, Khaliullin T, Jiang P, Hasanaj E, Ovando-Ricardez JA, Bueno M, Rahman I, Pryhuber GS, Li D, Ma Q, Finkel T, Königshoff M, Eickelberg O, Rojas M, Mora AL, Lugo-Martinez J, Bar-Joseph Z

Genome biology.. 2024 November 825 (1):288. Epub 11/08/2024.

Precision Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research. An Official American Thoracic Society Workshop Report.

Lehmann M, Krishnan R, Sucre J, Kulkarni HS, Pineda RH, Anderson C, Banovich NE, Behrsing HP, Dean CH, Haak A, Gosens R, Kaminski N, Zagorska A, Koziol-White C, Metcalf JP, Kim YH, Loebel C, Neptune E, Noel A, Raghu G, Sewald K, Sharma A, Suki B, Sperling A, Tatler A, Turner S, Rosas IO, van Ry P, Wille T, Randell SH, Pryhuber G, Rojas M, Bourke J, Königshoff M

American journal of respiratory cell and molecular biology.. 2024 November 5 Epub 11/05/2024.

Cell Population-resolved Multi-Omics Atlas of the Developing Lung.

Ushakumary MG, Feng S, Bandyopadhyay G, Olson H, Weitz KK, Huyck HL, Poole C, Purkerson JM, Bhattacharya S, Ljungberg MC, Mariani TJ, Deutsch GH, Misra RS, Carson JP, Adkins JN, Pryhuber GS, Clair G

American journal of respiratory cell and molecular biology.. 2024 October 24 Epub 10/24/2024.

Integrating -glycan and CODEX imaging reveal cell-specific protein glycosylation in healthy human lung.

Veli?kovi? D, Purkerson J, Bhotika H, Huyck H, Clair G, Pryhuber GS, Anderton C

bioRxiv : the preprint server for biology.. 2024 October 8 Epub 10/08/2024.

Three Dimensional Multiscalar Neurovascular Nephron Connectivity Map of the Human Kidney Across the Lifespan.

McLaughlin L, Zhang B, Sharma S, Knoten AL, Kaushal M, Purkerson JM, Huyck H, Pryhuber GS, Gaut JP, Jain S

bioRxiv : the preprint server for biology.. 2024 July 30 Epub 07/30/2024.

Discovery of optimal cell type classification marker genes from single cell RNA sequencing data.

Liu A, Peng B, Pankajam AV, Duong TE, Pryhuber G, Scheuermann RH, Zhang Y

bioRxiv : the preprint server for biology.. 2024 June 26 Epub 06/26/2024.

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage.

Börner K, Blood PD, Silverstein JC, Ruffalo M, Teichmann SA, Pryhuber G, Misra R, Purkerson J, Fan J, Hickey JW, Molla G, Xu C, Zhang Y, Weber G, Jain Y, Qaurooni D, Kong Y, , Bueckle A, Herr BW

bioRxiv : the preprint server for biology.. 2024 May 22 Epub 05/22/2024.

Bulk RNA sequencing of human pediatric lung cell populations reveals unique transcriptomic signature associated with postnatal pulmonary development.

Bandyopadhyay G, Jehrio MG, Baker C, Bhattacharya S, Misra RS, Huyck HL, Chu CY, Myers JR, Ashton J, Polter S, Cochran M, Bushnell T, Dutra J, Katzman PJ, Deutsch GH, Mariani TJ, Pryhuber GS

American journal of physiology. Lung cellular and molecular physiology.. 2024 May 1326 (5):L604-L617. Epub 03/05/2024.

Microbiota-derived inosine programs protective CD8 T cell responses against influenza in newborns.

Stevens J, Culberson E, Kinder J, Ramiriqui A, Gray J, Bonfield M, Shao TY, Al Gharabieh F, Peterson L, Steinmeyer S, Zacharias W, Pryhuber G, Paul O, Sengupta S, Alenghat T, Way SS, Deshmukh H

bioRxiv : the preprint server for biology.. 2024 April 13 Epub 04/13/2024.

Single-Cell Transcriptomic Profiling Identifies Molecular Phenotypes of Newborn Human Lung Cells.

Bhattacharya S, Myers JA, Baker C, Guo M, Danopoulos S, Myers JR, Bandyopadhyay G, Romas ST, Huyck HL, Misra RS, Dutra J, Holden-Wiltse J, McDavid AN, Ashton JM, Al Alam D, Potter SS, Whitsett JA, Xu Y, Pryhuber GS, Mariani TJ

Genes.. 2024 February 2615 (3)Epub 02/26/2024.

Single-cell resolution of human airway epithelial cells exposed to bronchiolitis obliterans-associated chemicals.

Chu CY, Kim SY, Pryhuber GS, Mariani TJ, McGraw MD

American journal of physiology. Lung cellular and molecular physiology.. 2024 February 1326 (2):L135-L148. Epub 12/12/2023.

LungMAP Portal Ecosystem: Systems-level Exploration of the Lung.

Gaddis N, Fortriede J, Guo M, Bardes EE, Kouril M, Tabar S, Burns K, Ardini-Poleske ME, Loos S, Schnell D, Jin K, Iyer B, Du Y, Huo BX, Bhattacharjee A, Korte J, Munshi R, Smith V, Herbst A, Kitzmiller JA, Clair GC, Carson JP, Adkins J, Morrisey EE, Pryhuber GS, Misra R, Whitsett JA, Sun X, Heathorn T, Paten B, Prasath VBS, Xu Y, Tickle T, Aronow BJ, Salomonis N,

American journal of respiratory cell and molecular biology.. 2024 February 70 (2):129-139. Epub 1900 01 01.

CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.

Hirani DV, Thielen F, Mansouri S, Danopoulos S, Vohlen C, Haznedar-Karakaya P, Mohr J, Wilke R, Selle J, Grosch T, Mizik I, Odenthal M, Alvira CM, Kuiper-Makris C, Pryhuber GS, Pallasch C, van Koningsbruggen-Rietschel S, Al-Alam D, Seeger W, Savai R, Dötsch J, Alejandre Alcazar MA

Inflammation and regeneration.. 2023 October 2443 (1):52. Epub 10/24/2023.

New insights into the natural history of bronchopulmonary dysplasia from proteomics and multiplexed immunohistochemistry.

Dylag AM, Misra RS, Bandyopadhyay G, Poole C, Huyck HL, Jehrio MG, Haak J, Deutsch GH, Dvorak C, Olson HM, Paurus V, Katzman P, Woo J, Purkerson JM, Adkins JN, Mariani TJ, Clair GC, Pryhuber GS

American journal of physiology. Lung cellular and molecular physiology.. 2023 October 1325 (4):L419-L433. Epub 07/25/2023.

Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.

Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Casals AM, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA, Vlachos IS, Muller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL, Börner K, Radtke AJ

Nature methods.. 2023 August 20 (8):1174-1178. Epub 07/19/2023.

Guided construction of single cell reference for human and mouse lung.

Guo M, Morley MP, Jiang C, Wu Y, Li G, Du Y, Zhao S, Wagner A, Cakar AC, Kouril M, Jin K, Gaddis N, Kitzmiller JA, Stewart K, Basil MC, Lin SM, Ying Y, Babu A, Wikenheiser-Brokamp KA, Mun KS, Naren AP, Clair G, Adkins JN, Pryhuber GS, Misra RS, Aronow BJ, Tickle TL, Salomonis N, Sun X, Morrisey EE, Whitsett JA, , Xu Y

Nature communications.. 2023 July 2914 (1):4566. Epub 07/29/2023.

Developmental diversity and unique sensitivity to injury of lung endothelial subtypes during postnatal growth.

Zanini F, Che X, Knutsen C, Liu M, Suresh NE, Domingo-Gonzalez R, Dou SH, Zhang D, Pryhuber GS, Jones RC, Quake SR, Cornfield DN, Alvira CM

iScience.. 2023 March 1726 (3):106097. Epub 01/31/2023.

Preparation of noninfectious scRNAseq samples from SARS-CoV-2-infected epithelial cells.

Osborn RM, Leach J, Zanche M, Ashton JM, Chu C, Thakar J, Dewhurst S, Rosenberger S, Pavelka M, Pryhuber GS, Mariani TJ, Anderson CS

PloS one.. 2023 18 (2):e0281898. Epub 02/24/2023.

Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease.

Xu X, Jin K, Bais AS, Zhu W, Yagi H, Feinstein TN, Nguyen PK, Criscione JD, Liu X, Beutner G, Karunakaran KB, Rao KS, He H, Adams P, Kuo CK, Kostka D, Pryhuber GS, Shiva S, Ganapathiraju MK, Porter GA, Lin JI, Aronow B, Lo CW

Cell stem cell.. 2022 May 529 (5):840-855.e7. Epub 04/07/2022.

Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy.

McDavid A, Laniewski N, Grier A, Gill AL, Kessler HA, Huyck H, Carbonell E, Holden-Wiltse J, Bandyopadhyay S, Carnahan J, Dylag AM, Topham DJ, Falsey AR, Caserta MT, Pryhuber GS, Gill SR, Scheible KM

iScience.. 2022 April 1525 (4):104007. Epub 03/01/2022.

Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.

Xu J, Xu L, Sui P, Chen J, Moya EA, Hume P, Janssen WJ, Duran JM, Thistlethwaite P, Carlin A, Gulleman P, Banaschewski B, Goldy MK, Yuan JX, Malhotra A, Pryhuber G, Crotty-Alexander L, Deutsch G, Young LR, Sun X

Developmental cell.. 2022 April 1157 (7):839-853.e6. Epub 03/17/2022.

Neonatal Hyperoxia Activates Activating Transcription Factor 4 to Stimulate Folate Metabolism and Alveolar Epithelial Type 2 Cell Proliferation.

Yee M, McDavid AN, Cohen ED, Huyck HL, Poole C, Altman BJ, Maniscalco WM, Deutsch GH, Pryhuber GS, O'Reilly MA

American journal of respiratory cell and molecular biology.. 2022 April 66 (4):402-414. Epub 1900 01 01.

Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia.

Hirani D, Alvira CM, Danopoulos S, Milla C, Donato M, Tian L, Mohr J, Dinger K, Vohlen C, Selle J, Koningsbruggen-Rietschel SV, Barbarino V, Pallasch C, Rose-John S, Odenthal M, Pryhuber GS, Mansouri S, Savai R, Seeger W, Khatri P, Al Alam D, Dötsch J, Alejandre Alcazar MA

The European respiratory journal.. 2022 February 59 (2)Epub 02/17/2022.

Proteomic Analysis of Human Lung Development.

Clair G, Bramer LM, Misra R, McGraw MD, Bhattacharya S, Kitzmiller JA, Feng S, Danna VG, Bandyopadhyay G, Bhotika H, Huyck HL, Deutsch GH, Mariani TJ, Carson J, Whitsett JA, Pryhuber GS, Adkins JN, Ansong C

American journal of respiratory and critical care medicine.. 2022 January 15205 (2):208-218. Epub 1900 01 01.

A census of the lung: CellCards from LungMAP.

Sun X, Perl AK, Li R, Bell SM, Sajti E, Kalinichenko VV, Kalin TV, Misra RS, Deshmukh H, Clair G, Kyle J, Crotty Alexander LE, Silva JM, Kitzmiller JA, Wikenheiser-Brokamp KA, Deutsch G, Guo M, Du Y, Morley MP, Valdez MJ, Yu HV, Jin K, Bardes EE, Zepp JA, Neithamer T, Basil MC, Zacharias WJ, Verheyden J, Young R, Bandyopadhyay G, Lin S, Ansong C, Adkins J, Salomonis N, Aronow BJ, Xu Y, Pryhuber G, Whitsett J, Morrisey EE,

Developmental cell.. 2022 January 1057 (1):112-145.e2. Epub 12/21/2021.

Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury.

Ha AW, Bai T, Ebenezer DL, Sethi T, Sudhadevi T, Mangio LA, Garzon S, Pryhuber GS, Natarajan V, Harijith A

Thorax.. 2022 January 77 (1):47-57. Epub 04/21/2021.

Reduced Notch1 Cleavage Promotes the Development of Pulmonary Hypertension.

Wang S, Zhu G, Jiang D, Rhen J, Li X, Liu H, Lyu Y, Tsai P, Rose Y, Nguyen T, White RJ, Pryhuber GS, Mariani TJ, Li C, Mohan A, Xu Y, Pang J

Hypertension.. 2022 January 79 (1):79-92. Epub 11/05/2021.

An optimized approach and inflation media for obtaining complimentary mass spectrometry-based omics data from human lung tissue.

Lukowski JK, Olson H, Velickovic M, Wang J, Kyle JE, Kim YM, Williams SM, Zhu Y, Huyck HL, McGraw MD, Poole C, Rogers L, Misra R, Alexandrov T, Ansong C, Pryhuber GS, Clair G, Adkins JN, Carson JP, Anderton CR

Frontiers in molecular biosciences.. 2022 9 :1022775. Epub 11/16/2022.

Anatomical structures, cell types and biomarkers of the Human Reference Atlas.

Börner K, Teichmann SA, Quardokus EM, Gee JC, Browne K, Osumi-Sutherland D, Herr BW, Bueckle A, Paul H, Haniffa M, Jardine L, Bernard A, Ding SL, Miller JA, Lin S, Halushka MK, Boppana A, Longacre TA, Hickey J, Lin Y, Valerius MT, He Y, Pryhuber G, Sun X, Jorgensen M, Radtke AJ, Wasserfall C, Ginty F, Ho J, Sunshine J, Beuschel RT, Brusko M, Lee S, Malhotra R, Jain S, Weber G

Nature cell biology.. 2021 November 23 (11):1117-1128. Epub 11/08/2021.

Low-dose hyperoxia primes airways for fibrosis in mice after influenza A infection.

Dylag AM, Haak J, Warren R, Yee M, Pryhuber GS, O'Reilly MA

American journal of physiology. Lung cellular and molecular physiology.. 2021 October 1321 (4):L750-L763. Epub 07/29/2021.

Retraction notice for: "miR-184 mediates hyperoxia-induced injury by targeting cell death and angiogenesis signalling pathways in the developing lung." Dilip Shah, Karmyodh Sandhu, Pragnya Das, Zubair H. Aghai, Sture Andersson, Gloria Pryhuber and Vineet Bhandari. 2020; in press.

Shah D, Sandhu K, Das P, Aghai ZH, Andersson S, Pryhuber G, Bhandari V

The European respiratory journal.. 2021 September 58 (3)Epub 10/01/2021.

Airway Gene Expression Correlates of Respiratory Syncytial Virus Disease Severity and Microbiome Composition in Infants.

Chu CY, Qiu X, McCall MN, Wang L, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Pryhuber GS, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Mariani TJ

The Journal of infectious diseases.. 2021 May 20223 (9):1639-1649. Epub 1900 01 01.

Neonatal hyperoxia inhibits proliferation and survival of atrial cardiomyocytes by suppressing fatty acid synthesis.

Cohen ED, Yee M, Porter GA, Ritzer EE, McDavid AN, Brookes PS, Pryhuber GS, O'Reilly MA

JCI insight.. 2021 March 86 (5)Epub 03/08/2021.

MicroRNA 219-5p inhibits alveolarization by reducing platelet derived growth factor receptor-alpha.

Freeman A, Qiao L, Olave N, Rezonzew G, Gentle S, Halloran B, Pryhuber GS, Gaggar A, Tipple TE, Ambalavanan N, Lal CV

Respiratory research.. 2021 February 1722 (1):57. Epub 02/17/2021.

Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes.

Wang A, Chiou J, Poirion OB, Buchanan J, Valdez MJ, Verheyden JM, Hou X, Kudtarkar P, Narendra S, Newsome JM, Guo M, Faddah DA, Zhang K, Young RE, Barr J, Sajti E, Misra R, Huyck H, Rogers L, Poole C, Whitsett JA, Pryhuber G, Xu Y, Gaulton KJ, Preissl S, Sun X,

eLife.. 2020 November 99 Epub 11/09/2020.

Elevated FiO increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium.

Myti D, Gunjak M, Casado F, Khaghani Raziabad S, Nardiello C, Vadász I, Herold S, Pryhuber GS, Seeger W, Morty RE

American journal of physiology. Lung cellular and molecular physiology.. 2020 October 1319 (4):L670-L674. Epub 09/02/2020.

Early Neonatal Oxygen Exposure Predicts Pulmonary Morbidity and Functional Deficits at 1 Year.

Dylag AM, Kopin HG, O'Reilly MA, Wang H, Davis SD, Ren CL, Pryhuber GS

The Journal of pediatrics.. 2020 August 223 :20-28.e2. Epub 1900 01 01.

Eight practices for data management to enable team data science.

McDavid A, Corbett AM, Dutra JL, Straw AG, Topham DJ, Pryhuber GS, Caserta MT, Gill SR, Scheible KM, Holden-Wiltse J

Journal of clinical and translational science.. 2020 June 235 (1):e14. Epub 06/23/2020.

Disruption of normal patterns of FOXF1 expression in a lethal disorder of lung development.

Steiner LA, Getman M, Schiralli Lester GM, Iqbal MA, Katzman P, Szafranski P, Stankiewicz P, Bhattacharya S, Mariani T, Pryhuber G, Lin X, Young JL, Dean DA, Scheible K

Journal of medical genetics.. 2020 May 57 (5):296-300. Epub 10/29/2019.

CX3CR1 as a respiratory syncytial virus receptor in pediatric human lung.

Anderson CS, Chu CY, Wang Q, Mereness JA, Ren Y, Donlon K, Bhattacharya S, Misra RS, Walsh EE, Pryhuber GS, Mariani TJ

Pediatric research.. 2020 April 87 (5):862-867. Epub 11/14/2019.

Urine gastrin-releasing peptide in the first week correlates with bronchopulmonary dysplasia and post-prematurity respiratory disease.

Voynow JA, Fisher K, Sunday ME, Cotten CM, Hamvas A, Hendricks-Muñoz KD, Poindexter BB, Pryhuber GS, Ren CL, Ryan RM, Sharp JK, Young SP, Zhang H, Greenberg RG, Herring AH, Davis SD

Pediatric pulmonology.. 2020 April 55 (4):899-908. Epub 01/29/2020.

WNT5a-ROR Signaling Is Essential for Alveologenesis.

Li C, Smith SM, Peinado N, Gao F, Li W, Lee MK, Zhou B, Bellusci S, Pryhuber GS, Ho HH, Borok Z, Minoo P

Cells.. 2020 February 79 (2)Epub 02/07/2020.

A novel in vitro model of primary human pediatric lung epithelial cells.

Wang Q, Bhattacharya S, Mereness JA, Anderson C, Lillis JA, Misra RS, Romas S, Huyck H, Howell A, Bandyopadhyay G, Donlon K, Myers JR, Ashton J, Pryhuber GS, Mariani TJ

Pediatric research.. 2020 February 87 (3):511-517. Epub 02/18/2019.

Alveolar Airspace Size in Healthy and Diseased Infant Lungs Measured via Hyperpolarized 3He Gas Diffusion Magnetic Resonance Imaging.

Higano NS, Thomen RP, Quirk JD, Huyck HL, Hahn AD, Fain SB, Pryhuber GS, Woods JC

Neonatology.. 2020 117 (6):704-712. Epub 11/11/2020.

Lymphocyte-Specific Biomarkers Associated With Preterm Birth and Bronchopulmonary Dysplasia.

Bhattacharya S, Mereness JA, Baran AM, Misra RS, Peterson DR, Ryan RM, Reynolds AM, Pryhuber GS, Mariani TJ

Frontiers in immunology.. 2020 11 :563473. Epub 01/21/2021.

Measuring the Severity of Respiratory Illness in the First 2 Years of Life in Preterm and Term Infants.

Caserta MT, Yang H, Bandyopadhyay S, Qiu X, Gill SR, Java J, McDavid A, Falsey AR, Topham DJ, Holden-Wiltse J, Scheible K, Pryhuber G

The Journal of pediatrics.. 2019 November 214 :12-19.e3. Epub 07/31/2019.

Secondary crest myofibroblast PDGFR? controls the elastogenesis pathway via a secondary tier of signaling networks during alveologenesis.

Li C, Lee MK, Gao F, Webster S, Di H, Duan J, Yang CY, Bhopal N, Peinado N, Pryhuber G, Smith SM, Borok Z, Bellusci S, Minoo P

Development.. 2019 August 9146 (15)Epub 08/09/2019.

Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation.

Jiang Y, Luo Y, Tang Y, Moats R, Warburton D, Zhou S, Lou J, Pryhuber GS, Shi W, Wang LL

Scientific reports.. 2019 March 289 (1):5296. Epub 03/28/2019.

TREM-1 Attenuates RIPK3-mediated Necroptosis in Hyperoxia-induced Lung Injury in Neonatal Mice.

Syed MA, Shah D, Das P, Andersson S, Pryhuber G, Bhandari V

American journal of respiratory cell and molecular biology.. 2019 March 60 (3):308-322. Epub 1900 01 01.

Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung

Am J Physiol Lung Cell Mol Physiol. 2019; 317(3): L347-L360.

Alterations in VASP phosphorylation and profilin1 and cofilin1 expression in hyperoxic lung injury and BPD.

Ali M, Heyob K, Tipple TE, Pryhuber GS, Rogers LK

Respiratory research.. 2018 November 2119 (1):229. Epub 11/21/2018.

Renewed Promise of Nonionizing Radiation Imaging for Chronic Lung Disease in Preterm Infants.

Pryhuber GS

American journal of respiratory and critical care medicine.. 2018 November 15198 (10):1248-1249. Epub 1900 01 01.

Neonatal gut and respiratory microbiota: coordinated development through time and space.

Grier A, McDavid A, Wang B, Qiu X, Java J, Bandyopadhyay S, Yang H, Holden-Wiltse J, Kessler HA, Gill AL, Huyck H, Falsey AR, Topham DJ, Scheible KM, Caserta MT, Pryhuber GS, Gill SR

Microbiome.. 2018 October 266 (1):193. Epub 10/26/2018.

Dissociation, cellular isolation, and initial molecular characterization of neonatal and pediatric human lung tissues.

Bandyopadhyay G, Huyck HL, Misra RS, Bhattacharya S, Wang Q, Mereness J, Lillis JA, Myers JR, Ashton J, Bushnell T, Cochran M, Holden-Wiltse J, Katzman P, Deutsch GH, Whitsett JA, Xu Y, Mariani TJ, Pryhuber GS

American journal of physiology. Lung cellular and molecular physiology.. 2018 October 1315 (4):L576-L583. Epub 07/05/2018.

Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC-MS.

Zhu Y, Clair G, Chrisler W, Shen Y, Zhao R, Shukla A, Moore R, Misra R, Pryhuber G, Smith R, Ansong C, Kelly RT

Angewandte Chemie.. 2018 September 1757 (38):12370-12374. Epub 06/14/2018.

Cell type-resolved human lung lipidome reveals cellular cooperation in lung function.

Kyle JE, Clair G, Bandyopadhyay G, Misra RS, Zink EM, Bloodsworth KJ, Shukla AK, Du Y, Lillis J, Myers JR, Ashton J, Bushnell T, Cochran M, Deutsch G, Baker ES, Carson JP, Mariani TJ, Xu Y, Whitsett JA, Pryhuber G, Ansong C

Scientific reports.. 2018 September 78 (1):13455. Epub 09/07/2018.

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development.

Luo Y, Li N, Chen H, Fernandez GE, Warburton D, Moats R, Mecham RP, Krenitsky D, Pryhuber GS, Shi W

Scientific reports.. 2018 May 298 (1):8334. Epub 05/29/2018.

T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy.

Scheible KM, Emo J, Laniewski N, Baran AM, Peterson DR, Holden-Wiltse J, Bandyopadhyay S, Straw AG, Huyck H, Ashton JM, Tripi KS, Arul K, Werner E, Scalise T, Maffett D, Caserta M, Ryan RM, Reynolds AM, Ren CL, Topham DJ, Mariani TJ, Pryhuber GS

JCI insight.. 2018 February 223 (4)Epub 02/22/2018.

Type VI collagen promotes lung epithelial cell spreading and wound-closure.

Mereness JA, Bhattacharya S, Wang Q, Ren Y, Pryhuber GS, Mariani TJ

PloS one.. 2018 13 (12):e0209095. Epub 12/14/2018.

Impact of prematurity and nutrition on the developing gut microbiome and preterm infant growth.

Grier A, Qiu X, Bandyopadhyay S, Holden-Wiltse J, Kessler HA, Gill AL, Hamilton B, Huyck H, Misra S, Mariani TJ, Ryan RM, Scholer L, Scheible KM, Lee YH, Caserta MT, Pryhuber GS, Gill SR

Microbiome.. 2017 December 115 (1):158. Epub 12/11/2017.

LungMAP: The Molecular Atlas of Lung Development Program.

Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, Pryhuber GS, Warburton D, Whitsett JA, Palmer SM, Ambalavanan N, LungMAP Consortium T

American journal of physiology. Lung cellular and molecular physiology.. 2017 November 1313 (5):L733-L740. Epub 08/10/2017.

Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs.

Syed M, Das P, Pawar A, Aghai ZH, Kaskinen A, Zhuang ZW, Ambalavanan N, Pryhuber G, Andersson S, Bhandari V

Nature communications.. 2017 October 278 (1):1173. Epub 10/27/2017.

miR-29b supplementation decreases expression of matrix proteins and improves alveolarization in mice exposed to maternal inflammation and neonatal hyperoxia.

Durrani-Kolarik S, Pool CA, Gray A, Heyob KM, Cismowski MJ, Pryhuber GS, Lee LJ, Yang Z, Tipple TE, Rogers LK

American journal of physiology. Lung cellular and molecular physiology.. 2017 August 1313 (2):L339-L349. Epub 05/04/2017.

Permission form synopses to improve parents' understanding of research: a randomized trial.

D'Angio CT, Wang H, Hunn JE, Pryhuber GS, Chess PR, Lakshminrusimha S

Journal of perinatology : official journal of the California Perinatal Association.. 2017 June 37 (6):735-739. Epub 03/30/2017.

Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development.

Du Y, Kitzmiller JA, Sridharan A, Perl AK, Bridges JP, Misra RS, Pryhuber GS, Mariani TJ, Bhattacharya S, Guo M, Potter SS, Dexheimer P, Aronow B, Jobe AH, Whitsett JA, Xu Y

Thorax.. 2017 May 72 (5):481-484. Epub 01/09/2017.

Viral Respiratory Infections in Preterm Infants during and after Hospitalization.

Caserta MT, Yang H, Gill SR, Holden-Wiltse J, Pryhuber G

The Journal of pediatrics.. 2017 March 182 :53-58.e3. Epub 12/30/2016.

Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.

Angara S, Syed M, Das P, Janér C, Pryhuber G, Rahman A, Andersson S, Homer RJ, Bhandari V

American journal of respiratory cell and molecular biology.. 2016 November 55 (5):722-735. Epub 1900 01 01.

Flow-based sorting of neonatal lymphocyte populations for transcriptomics analysis.

Misra RS, Bhattacharya S, Huyck HL, Wang JE, Slaunwhite CG, Slaunwhite SL, Wightman TR, Secor-Socha S, Misra SK, Bushnell TP, Reynolds AM, Ryan RM, Quataert SA, Pryhuber GS, Mariani TJ

Journal of immunological methods.. 2016 October 437 :13-20. Epub 07/18/2016.

Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants.

Scheible KM, Emo J, Yang H, Holden-Wiltse J, Straw A, Huyck H, Misra S, Topham DJ, Ryan RM, Reynolds AM, Mariani TJ, Pryhuber GS

Clinical immunology : the official journal of the Clinical Immunology Society.. 2015 December 161 (2):65-74. Epub 07/29/2015.

Postnatal Infections and Immunology Affecting Chronic Lung Disease of Prematurity.

Pryhuber GS

Clinics in perinatology.. 2015 December 42 (4):697-718. Epub 10/01/2015.

Bronchopulmonary Dysplasia--The Search for Answers Continues.

Kallapur SG, Pryhuber GS

Clinics in perinatology.. 2015 December 42 (4):xix-xx. Epub 1900 01 01.

Attenuation of miR-17?92 Cluster in Bronchopulmonary Dysplasia.

Rogers LK, Robbins M, Dakhlallah D, Yang Z, Lee LJ, Mikhail M, Nuovo G, Pryhuber GS, McGwin G, Marsh CB, Tipple TE

Annals of the American Thoracic Society.. 2015 October 12 (10):1506-13. Epub 1900 01 01.

Preterm cord blood CD4? T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4? T cells in bronchopulmonary dysplasia.

Misra R, Shah S, Fowell D, Wang H, Scheible K, Misra S, Huyck H, Wyman C, Ryan RM, Reynolds AM, Mariani T, Katzman PJ, Pryhuber GS

Human immunology.. 2015 May 76 (5):329-338. Epub 03/20/2015.

Respiratory consequences of prematurity: evolution of a diagnosis and development of a comprehensive approach.

Maitre NL, Ballard RA, Ellenberg JH, Davis SD, Greenberg JM, Hamvas A, Pryhuber GS

Journal of perinatology : official journal of the California Perinatal Association.. 2015 May 35 (5):313-321. Epub 03/26/2015.

Prematurity and respiratory outcomes program (PROP): study protocol of a prospective multicenter study of respiratory outcomes of preterm infants in the United States.

Pryhuber GS, Maitre NL, Ballard RA, Cifelli D, Davis SD, Ellenberg JH, Greenberg JM, Kemp J, Mariani TJ, Panitch H, Ren C, Shaw P, Taussig LM, Hamvas A,

BMC pediatrics.. 2015 April 1015 :37. Epub 04/10/2015.

Correction: Neonatal Periostin Knockout Mice Are Protected from Hyperoxia-Induced Alveolar Simplication.

Bozyk PD, Bentley JK, Popova AP, Anyanwu AC, Linn MD, Goldsmith AM, Pryhuber GS, Moore BB, Hershenson MB

PloS one.. 2015 10 (6):e0130369. Epub 06/11/2015.

Tracheal Aspirate Levels of the Matricellular Protein SPARC Predict Development of Bronchopulmonary Dysplasia.

Popova AP, Cui TX, Kaciroti N, Goldsmith AM, Linn MJ, Pryhuber GS, Hershenson MB

PloS one.. 2015 10 (12):e0144122. Epub 12/11/2015.

Reduced platelet-derived growth factor receptor expression is a primary feature of human bronchopulmonary dysplasia.

Popova AP, Bentley JK, Cui TX, Richardson MN, Linn MJ, Lei J, Chen Q, Goldsmith AM, Pryhuber GS, Hershenson MB

American journal of physiology. Lung cellular and molecular physiology.. 2014 August 1307 (3):L231-9. Epub 06/06/2014.

The impact of postnatal antibiotics on the preterm intestinal microbiome.

Dardas M, Gill SR, Grier A, Pryhuber GS, Gill AL, Lee YH, Guillet R

Pediatric research.. 2014 August 76 (2):150-8. Epub 05/12/2014.

Hyperoxia and interferon-?-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway.

Choo-Wing R, Syed MA, Harijith A, Bowen B, Pryhuber G, Janér C, Andersson S, Homer RJ, Bhandari V

American journal of respiratory cell and molecular biology.. 2013 June 48 (6):749-57. Epub 1900 01 01.

Stability of T cell phenotype and functional assays following heparinized umbilical cord blood collection.

Scheible K, Secor-Socha S, Wightman T, Wang H, Mariani TJ, Topham DJ, Pryhuber G, Quataert S

Cytometry. Part A : the journal of the International Society for Analytical Cytology.. 2012 November 81 (11):937-49. Epub 10/01/2012.

Glycogen synthase kinase-3?/?-catenin signaling regulates neonatal lung mesenchymal stromal cell myofibroblastic differentiation.

Popova AP, Bentley JK, Anyanwu AC, Richardson MN, Linn MJ, Lei J, Wong EJ, Goldsmith AM, Pryhuber GS, Hershenson MB

American journal of physiology. Lung cellular and molecular physiology.. 2012 September 303 (5):L439-48. Epub 07/06/2012.

Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia.

Bhattacharya S, Go D, Krenitsky DL, Huyck HL, Solleti SK, Lunger VA, Metlay L, Srisuma S, Wert SE, Mariani TJ, Pryhuber GS

American journal of respiratory and critical care medicine.. 2012 August 15186 (4):349-58. Epub 06/21/2012.

Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication.

Bozyk PD, Bentley JK, Popova AP, Anyanwu AC, Linn MD, Goldsmith AM, Pryhuber GS, Moore BB, Hershenson MB

PloS one.. 2012 7 (2):e31336. Epub 02/17/2012.

TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease.

Papuga MO, Kwok E, You Z, Rubery PT, Dougherty PE, Pryhuber G, Beck CA, Hilton MJ, Awad HA, Schwarz EM

Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2011 September 29 (9):1367-74. Epub 03/28/2011.

FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease.

Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I

The Journal of immunology : official journal of the American Association of Immunologists.. 2011 July 15187 (2):987-98. Epub 06/20/2011.

CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses.

Scheible K, Zhang G, Baer J, Azadniv M, Lambert K, Pryhuber G, Treanor JJ, Topham DJ

Vaccine.. 2011 March 329 (11):2159-68. Epub 01/04/2011.

Inflammatory cytokines and antioxidants in midtrimester amniotic fluid: correlation with pregnancy outcome.

Pressman EK, Thornburg LL, Glantz JC, Earhart A, Wall PD, Ashraf M, Pryhuber GS, Woods JR

American journal of obstetrics and gynecology.. 2011 February 204 (2):155.e1-7. Epub 10/14/2010.

Effect of cumulative oxygen exposure on respiratory symptoms during infancy among VLBW infants without bronchopulmonary dysplasia.

Stevens TP, Dylag A, Panthagani I, Pryhuber G, Halterman J

Pediatric pulmonology.. 2010 April 45 (4):371-9. Epub 1900 01 01.

IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells.

Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.. 2009 May 29 (5):273-84. Epub 1900 01 01.

G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development.

Pang J, Hoefen R, Pryhuber GS, Wang J, Yin G, White RJ, Xu X, O'Dell MR, Mohan A, Michaloski H, Massett MP, Yan C, Berk BC

Circulation.. 2009 March 24119 (11):1524-32. Epub 03/09/2009.

The effects of interleukin-1beta in tumor necrosis factor-alpha-induced acute pulmonary inflammation in mice.

Saperstein S, Huyck H, Kimball E, Johnston C, Finkelstein J, Pryhuber G

Mediators of inflammation.. 2009 2009 :958658. Epub 11/04/2009.

Parenchymal cell TNF receptors contribute to inflammatory cell recruitment and respiratory failure in Pneumocystis carinii-induced pneumonia.

Pryhuber GS, Huyck HL, Bhagwat S, O'Reilly MA, Finkelstein JN, Gigliotti F, Wright TW

The Journal of immunology : official journal of the American Association of Immunologists.. 2008 July 15181 (2):1409-19. Epub 1900 01 01.

Pharmacotherapy of acute lung injury and acute respiratory distress syndrome.

Raghavendran K, Pryhuber GS, Chess PR, Davidson BA, Knight PR, Notter RH

Current medicinal chemistry.. 2008 15 (19):1911-24. Epub 1900 01 01.

Pathogenesis of bronchopulmonary dysplasia.

Chess PR, D'Angio CT, Pryhuber GS, Maniscalco WM

Seminars in perinatology.. 2006 August 30 (4):171-8. Epub 1900 01 01.

Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB.

Clifton DR, Rydkina E, Huyck H, Pryhuber G, Freeman RS, Silverman DJ, Sahni SK

International journal of medical microbiology : IJMM.. 2005 August 295 (4):267-78. Epub 1900 01 01.

Developmental regulation of p66Shc is altered by bronchopulmonary dysplasia in baboons and humans.

Lee MK, Pryhuber GS, Schwarz MA, Smith SM, Pavlova Z, Sunday ME

American journal of respiratory and critical care medicine.. 2005 June 15171 (12):1384-94. Epub 03/18/2005.

Acute tumor necrosis factor-alpha-induced liver injury in the absence of tumor necrosis factor receptor-associated factor 1 gene expression.

Pryhuber GS, Huyck HL, Roper JM, Cornejo J, O'Reilly MA, Pierce RH, Tsitsikov EN

The American journal of pathology.. 2005 June 166 (6):1637-45. Epub 1900 01 01.

TNF receptor signaling contributes to chemokine secretion, inflammation, and respiratory deficits during Pneumocystis pneumonia.

Wright TW, Pryhuber GS, Chess PR, Wang Z, Notter RH, Gigliotti F

The Journal of immunology : official journal of the American Association of Immunologists.. 2004 February 15172 (4):2511-21. Epub 1900 01 01.

Induction of chemokines by low-dose intratracheal silica is reduced in TNFR I (p55) null mice.

Pryhuber GS, Huyck HL, Baggs R, Oberdörster G, Finkelstein JN

Toxicological sciences : an official journal of the Society of Toxicology.. 2003 March 72 (1):150-7. Epub 1900 01 01.

Erythromycin for the prevention of chronic lung disease in intubated preterm infants at risk for, or colonized or infected with Ureaplasma urealyticum.

Mabanta CG, Pryhuber GS, Weinberg GA, Phelps DL

The Cochrane database of systematic reviews.. 2003 (4):CD003744. Epub 1900 01 01.

Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.

Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR

American journal of respiratory and critical care medicine.. 2002 December 1166 (11):1498-509. Epub 08/01/2002.

Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons.

Maniscalco WM, Watkins RH, Pryhuber GS, Bhatt A, Shea C, Huyck H

American journal of physiology. Lung cellular and molecular physiology.. 2002 April 282 (4):L811-23. Epub 1900 01 01.

Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia.

Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Metlay LA, Maniscalco WM

American journal of respiratory and critical care medicine.. 2001 November 15164 (10 Pt 1):1971-80. Epub 1900 01 01.

Bcl-2 family gene expression during severe hyperoxia induced lung injury.

O'Reilly MA, Staversky RJ, Huyck HL, Watkins RH, LoMonaco MB, D'Angio CT, Baggs RB, Maniscalco WM, Pryhuber GS

Laboratory investigation; a journal of technical methods and pathology.. 2000 December 80 (12):1845-54. Epub 1900 01 01.

Combined-modality therapy with inhaled nitric oxide and exogenous surfactant in term infants with acute respiratory failure.

Uy IP, Pryhuber GS, Chess PR, Notter RH

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2000 October 1 (2):107-10. Epub 1900 01 01.

Ablation of tumor necrosis factor receptor type I (p55) alters oxygen-induced lung injury.

Pryhuber GS, O'Brien DP, Baggs R, Phipps R, Huyck H, Sanz I, Nahm MH

American journal of physiology. Lung cellular and molecular physiology.. 2000 May 278 (5):L1082-90. Epub 1900 01 01.

Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2.

Pryhuber GS, Huyck HL, Staversky RJ, Finkelstein JN, O'Reilly MA

American journal of respiratory cell and molecular biology.. 2000 February 22 (2):150-6. Epub 1900 01 01.

Antagonistic effects of pyrrolidine dithiocarbamate and N-acetyl-L-cysteine on surfactant protein A and B mRNAs.

Khalak R, Huyck HL, Pryhuber GS

Experimental lung research.. 1999 September 25 (6):479-93. Epub 1900 01 01.

Regulation and function of pulmonary surfactant protein B.

Pryhuber GS

Molecular genetics and metabolism.. 1998 August 64 (4):217-28. Epub 1900 01 01.

Regulation of surfactant proteins A and B by TNF-? and phorbol ester independent of NF-?B.

Pryhuber GS, Khalak R, Zhao Q

American journal of physiology. Lung cellular and molecular physiology.. 1998 February 1274 (2):L289-L295. Epub 1900 01 01.

Regulation of surfactant proteins A and B by TNF-alpha and phorbol ester independent of NF-kappa B.

Pryhuber GS, Khalak R, Zhao Q

The American journal of physiology.. 1998 February 274 (2):L289-95. Epub 1900 01 01.

Epithelial-mesenchymal interactions in the alteration of gene expression and morphology following lung injury.

O'Reilly MA, Stripp BR, Pryhuber GS

Microscopy research and technique.. 1997 September 138 (5):473-9. Epub 1900 01 01.

Tumor necrosis factor-alpha decreases surfactant protein B mRNA in murine lung.

Pryhuber GS, Bachurski C, Hirsch R, Bacon A, Whitsett JA

The American journal of physiology.. 1996 May 270 (5 Pt 1):L714-21. Epub 1900 01 01.

Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription.

Bachurski CJ, Pryhuber GS, Glasser SW, Kelly SE, Whitsett JA

The Journal of biological chemistry.. 1995 August 18270 (33):19402-7. Epub 1900 01 01.

3'-untranslated region of SP-B mRNA mediates inhibitory effects of TPA and TNF-alpha on SP-B expression.

Pryhuber GS, Church SL, Kroft T, Panchal A, Whitsett JA

The American journal of physiology.. 1994 July 267 (1 Pt 1):L16-24. Epub 1900 01 01.

Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro.

Whitsett JA, Clark JC, Wispé JR, Pryhuber GS

The American journal of physiology.. 1992 June 262 (6 Pt 1):L688-93. Epub 1900 01 01.

Ontogeny of surfactant proteins A and B in human amniotic fluid as indices of fetal lung maturity.

Pryhuber GS, Hull WM, Fink I, McMahan MJ, Whitsett JA

Pediatric research.. 1991 December 30 (6):597-605. Epub 1900 01 01.

Phorbol ester inhibits surfactant protein SP-A and SP-B expression.

Pryhuber GS, O'Reilly MA, Clark JC, Hull WM, Fink I, Whitsett JA

The Journal of biological chemistry.. 1990 December 5265 (34):20822-8. Epub 1900 01 01.

Altered Elastic Fiber Morphology, Elastin Expression, and Alveolar Myofibroblast Distribution in Human Bronchopulmonary Dysplasia.

Pierce RA, Heintz C, Metlay LA, Huyck H, Pryhuber GS.

Pediatr Res. (in revision). .

Enhanced TNF alpha Induced Apoptosis of Pulmonary Epithelial Cell by Inhibition of TNF Receptor Associated Protein, TRAF1

Pryhuber GS, Huyck H, Kalburghi S, Macaluso K, Saperstein S, Tsitsikov E.

Am J Physiol (In Revision). .

Altered Elastic Fiber Morphology, Elastin Expression, and Alveolar Myofibroblas Ddistribution in Human Bronchopulmonary Dysplasia.

Pierce, RA, Heintz, C, Metlay, LA, Huyck, H and Pryhuber, GS.

pediatr Res. .

Enhanced TNF alpha Induced Apoptosis of Pulmonary Epithelial Cell by Inhibition of TNF Receptor Associated Protein, TRAF1. Am J Physiol.

Pryhuber, GS, Huyck, H, Kalburghi, S, Macaluso, K, Saperstein, S, Tsitsikov, E.

Books

Updates on Neonatal Chronic Lung Disease (2019)

Authors: S.Abman;N.Ambalavanan;M.ArdiniPoleske;J.Aschner;J.Baatz;C.Baker;E.Baker;V.Bhandari;D.Bush;J.Cheong;M.Chiafery;J.Collaco;C.DAngio;P.Davis;G.Deutsch;K.Dolma;L.Doyle;A.Dylag;O.Ekhaguere;S.Garantziotis;W.Hay;N.Higano;J.Ibrahim;E.Jensen;M. Keszler;H.Kirpalani;K.LimKua; Lakshminrusimha;C.Lal;S.Leary;S.Lynch;D.Malleske;E.Mandell;T.Mariani;R.Martin;C.McEvoy;S.McGrathMorrow;R.McKinney;R.Misra;L.Nelin;E.Patel;C.Richardson;R.Ryan;R.Savani; K.Scheible;B.Schmidt;E.Shepherd;L.Strueby;B.Thébaud;P.Vali;J.Woods

Publisher: Elsevier 2019

Neonatology: Pathophysiology and Management of the Newborn. (2015)

Chapter: Acute Respiratory Disorders of the Newborn

Authors: Whitsett JA, Rice WR, Pryhuber GS and Wert SE.

Publisher: Lippencott, Williams and Wilkins, New York, New York 2015

Bronchopulmonary Dysplasia: An Update. (2015)

Chapter: Postnatal Infections and Immunology Affecting Chronic Lung Disease of Prematurity.

Authors: Pryhuber, G.

Publisher: Clin Perinatol 2015

Bronchopulmonary Dysplasia: An update. (2015)

Authors: Kallapur, S.G. and Pryhuber, G.S., Ed.

Publisher: Clinics in Perinatology 2015

Lung Injury: Mechanisms, Pathophysiology, and Therapy (2005)

Chapter: Combined-Modality Therapy for Lung Injury

Authors: Pryhuber GS, D'Angio CT, Finkelstein JN, Notter RH

Publisher: Marcel-Dekker, New York, NY 2005

Neonatology: Pathophysiology and Management of the Newborn (2005)

Chapter: Acute Respiratory Disorders of the Newborn

Authors: Whitsett JA, Rice WR, Warner BB, Wert SE, Pryhuber GS

Publisher: Lippencott, Williams and Wilkins, New York, NY 2005

Neonatology: pathophysiology and management of the newborn (1999)

Chapter: Acute respiratory disorders of the newborn

Authors: Whitsett JA, Pryhuber GS, Rice WR, Warner BB, Wert SE.

Publisher: Lippencott, Williams and Wilkins, New York, NY 1999

Neonatology, Pathophysiology and Management of the Newborn (1993)

Chapter: Acute respiratory disorders of the newborn

Authors: Whitsett JA, Pryhuber GS, Rice WR, Warner BB, Wert SE.

Publisher: Lippencott Co., New York, NY 1993

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