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URMC / Research

Moving Medicine Forward

Scientist working with Petri dishes

The University of Rochester Medical Center (URMC) is home to more than 3,000 people dedicated to scientific research, studying common and rare illnesses, from cancer and heart disease to Parkinson’s and RSV. These efforts have led to therapies that have saved countless lives and improved human health locally, in the region, and across the globe.

Over the last five years, URMC has garnered more than $1.3 billion in biomedical research funding. Coupled with state-of-the-art research space, and high-end support services and shared resources, we’re building upon this strong legacy of research every day.

Meet Our Researchers

Our Impact

Explore how our scientists are improving care and making new treatments available to patients faster:

Cancer

Thanks to research, cancer patients have advantages that didn't exist 20 years ago—or in some cases, even a few months ago.

Investigating Cancer and Improving Care

RNA Biology

The Center for RNA Biology: From Genome to Therapeutics conducts research into the function, structure, and processing of RNA.

Discovering New Pathways to the Molecular Basis of Human Disease

Immunity & Infection

Several widely used vaccines that have improved the health of people around the world are rooted in infectious disease research at URMC.

Fighting Infections & Vaccine Research

Neuroscience

Neuroscience is at the cross section of discovery and innovation, aiming to reduce the burden of neuro-related disease.

Basic and translational Neuroscience research is woven into the fabric of the University

Orthopaedics

The Center for Musculoskeletal Research (CMSR) has been among the top 5 NIH-funded orthopaedic research centers in the nation for nearly 20 years.

Keeping Your Body Moving

Pediatrics

Every day, dedicated researchers—at Golisano Children’s Hospital, across URMC and throughout the University of Rochester—are working to improve the health of our most vulnerable patients: infants and children.

Making Children Healthier and Happier

Researcher Spotlight

Lynne Maquat, Ph.D. is an internationally recognized expert in the field of RNA biology in which she works to discover new cellular pathways and clues to the molecular basis of human disease. She is the founding director of the University’s Center for RNA Biology: From Genome to Therapeutics. In 2011 she was elected to the National Academy of Sciences and in 2017 she was elected to the National Academy of Medicine.

Research in the Maquat lab focuses on RNA decay pathways, largely in human cells, and their relevance to human diseases. One pathway, called nonsense-mediated mRNA decay (NMD) or mRNA surveillance, surveys all newly synthesized mRNAs during what we call a "pioneer" round of translation.

Visit the Maquat Lab