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Center for Biomedical Informatics

Center for Biomedical Informatics

URMC / Center for Biomedical Informatics / People

CBI Faculty

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Anthony Almudevar
Anthony Almudevar, Ph.D.
Research Interest: Genetics and bioinformatics

Ajay Anand
Ajay Anand, Ph.D.

John Ashton
John Ashton, Ph.D.
Research Interest:

Co-Director of the Rochester Genomics Center
Director, Wilmot Cancer Institute Shared Resources
Director, Functional Genomics Resource

Dirk Bohmann
Dirk Bohmann, Ph.D.
Research Interest:

The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and disease

Dr. Bohmann works part-time and doesn’t accept new students.

Jennifer Brisson
Jennifer Brisson, Ph.D.

Michael Bulger
Michael D. Bulger, Ph.D.
Research Interest: Chromatin domains and long-range activation by enhancers

W. Richard Burack
W. Richard Burack, M.D., Ph.D.
Research Interest: Activation induced cytidine deaminase (AID) impact on Follicular lymphoma (FL) tumors as a prognostic factor for Diffuse Large B-cell lymphoma (DLBCL)

Stephen Dewhurst
Stephen Dewhurst, Ph.D.
Research Interest:

Understanding the interaction of HIV with glial cells; Developing an improved live attenuated influenza vaccine (LAIV); Elucidating the host cell response to infection by viral pathogens (with emphasis on SARS-CoV-2 and Adeno-associated virus, AAV)

Sandhya Dwarkadas
Sandhya Dwarkadas, Ph.D.

Timothy Dye
Timothy Dye, Ph.D.
Research Interest: Developing and understanding community-driven solutions to public health problems

Justin Fay
Justin Fay, Ph.D.
Research Interest: The genetic basis of evolutionary change and specifically interested in the role of changes in gene regulation

Dragony Fu
Dragony Fu, Ph.D.
Research Interest: Nucleic acid modification and repair mechanisms linked to neurodevelopmental disorders, mitochondrial diseases, and cancer.

Steven Gill
Steven R. Gill, Ph.D.
Research Interest: Microbial pathogens and the impact of human microbial flora on human health and disease.

Laurent Glance
Laurent Glance, M.D.

Elizabeth Grayhack
Elizabeth Grayhack, Ph.D.
Research Interest: Role of the genetic code in regulating protein synthesis and mRNA metabolism in Saccharomyces cerevisiae.

Alan Grossfield
Alan Grossfield, Ph.D.
Research Interest:

Investigating membranes and membrane proteins via computer simulation

Jeffrey Hayes
Jeffrey J. Hayes, Ph.D.
Research Interest: Regulation of transcription, nuclear processes, related to chromatin structure and function

Hartmut Land
Hartmut Land, Ph.D.
Research Interest: Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism

Amanda Larracuente
Amanda Larracuente, Ph.D.
Research Interest: Satellite DNA (repetitive DNA typically found at centromeres and telomeres), Meiotic Drive, and Selfish DNA using genomic, population genetic, molecular and cytological methods.

Dongmei Li
Dongmei Li, Ph.D.

Richard Libby
Richard Libby, Ph.D.
Research Interest: Neurobiology of glaucoma, molecular processes that lead to retinal ganglion cell death.

Lynne Maquat
Lynne Maquat, Ph.D.
Research Interest:

RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.

Thomas Mariani
Thomas Mariani, Ph.D.
Research Interest:

Genetic and environmental susceptibility to developmental lung injury

David Mathews
David H. Mathews, M.D., Ph.D.
Research Interest: Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.

Matthew McCall
Matthew McCall, Ph.D.
Research Interest:

Developing methods to estimate gene regulatory networks from gene perturbation experiments

Andrew McDavid
Andrew McDavid, Ph.D.

Helene McMurray
Helene R. McMurray, Ph.D.
Research Interest: Analysis of gene regulatory networks in cancer; role of immunogenetics in transplant

David Mitten
David Mitten, M.D.

Cynthia Monaco
Cynthia Monaco, M.D., Ph.D.
Research Interest: Effect of the Microbiome/Virome on Mucosal and Systemic Inflammation in Health and Disease

Brendan Mort
Brendan Mort, Ph.D.

Tim Mosmann
Tim R. Mosmann, Ph.D.
Research Interest: The regulation of cytokine responses of human and mouse T-cell subsets in infections asthma, allergy and autoimmunity

Joshua Munger
Joshua C. Munger, Ph.D.
Research Interest: Mechanisms of metabolic network manipulation induced by viral infection and oncogenic mutation.

Patrick Murphy
Patrick J. Murphy, Ph.D.
Research Interest:

The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.

Mitchell O'Connell
Mitchell O'Connell, Ph.D.
Research Interest: Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool development

Alexander Paciorkowski
Alexander R. Paciorkowski, M.D.
Research Interest: Pediatric Neurology, Human Genetics

Eric Phizicky
Eric Phizicky, Ph.D.
Research Interest: tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.

Christoph Pröschel
Christoph Pröschel, Ph.D.
Research Interest:

Using primarily human pluripotent stem cell models, we examine astrocyte development in normal and pathological conditions, the role of astrocytes in modulating response to injury or stress, the role of altered RNA processing and translation in neural development, and the utility of glial precursor cells and their astrocytic progeny for cell transplantation therapy.

Xing Qiu
Xing Qiu, Ph.D.

Gaurav Sharma
Gaurav Sharma, Ph.D.
Research Interest: Computational biology of RNA; RNA comparative sequence analysis; RNA structure prediction; analysis of HIV RNA genomes.

Laurie Steiner
Laurie A. Steiner, M.D.
Research Interest:

Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.

Juilee Thakar
Juilee Thakar, Ph.D.
Research Interest: Systems approach utilizing bioinformatics, and dynamic modeling tools to study immune response to infections and vaccination.

David Topham
David Topham, Ph.D.
Research Interest:

Immune responses to respiratory viruses and experimental vaccines

Jack Werren
Jack Werren, Ph.D.
Research Interest: Evolutionary Genetics

Peng Yao
Peng Yao, Ph.D.
Research Interest:

Pathophysiological function and molecular mechanism of new non-coding RNAs and RNA-binding proteins and translational control in cardiac system and cardiovascular disease

Martin Zand
Martin S. Zand, M.D., Ph.D.