Lupus

Lupus can be difficult to diagnose because it can look different in different people. Our experienced health care team provides education, support, and the latest medicines—some of them delivered in our state-of-the-art infusion center. We also help you coordinate the appointments you need for lab work, X-rays, and other tests.

Since lupus is a systemic (whole body) disease, more than one specialist may be involved in diagnosing and managing your illness. This may include a rheumatologist (autoimmune diseases), a dermatologist (skin), a nephrologist (kidney), and other specialists depending on which part(s) of the body are being affected. 

Your provider will make a diagnosis based on exam findings, blood tests, and—in some cases—more specialized testing. Your doctor will discuss medications, depending on your symptoms.

There is no cure for lupus. The goal of treatment is to control the inflammation (swelling) to make you more comfortable and to prevent flares, or sudden worsening of symptoms.

Treatment Options

Medications

• Non-steroidal Anti-inflammatory Drugs (NSAIDs): NSAIDs are medicines that reduce pain and inflammation. There are many different NSAIDs. Some NSAIDs, such as ibuprofen and naproxen, are available over the counter. Others require a prescription.
• Corticosteroids: Corticosteroids work quickly to reduce inflammation and control “flares,” or sudden worsening of inflammation. Prednisone is one of the commonly used corticosteroids.
• Antimalarials: Most people with lupus take antimalarial medications, which help treat arthritis, fatigue, and rashes. They also help prevent flares. Hydroxychloroquine is a commonly used antimalarial.
• Immunosuppressants: These medications help control lupus symptoms by making the immune system less active so it stops attacking your body. Examples include azathioprine and mycophenolate.
• Biologics: These medications block proteins in the immune system that cause inflammation and other lupus symptoms. Belimumab is one example.

Lifestyle Changes

• Healthy Eating: The right combination of different foods can help you feel your best and maintain a healthy weight. Foods rich in omega-3s and antioxidants may help control inflammation. UR Medicine nutritionists can help you develop a diet plan that works best for you. Learn how UR Medicine's Improve Nutrition Program can help.
• Staying Active: Physical activity will improve your energy level, decrease stiffness, increase range of movement, elevate mood, and increase bone strength. People with lupus can safely exercise with the proper program, and we have informational materials to get you started. UR Medicine physical therapists can also work with you to devise an exercise regimen that’s best for you. Learn more about  UR Medicine Physical Therapy.
• Managing Stress: Stress can cause lupus flares. There’s no quick-fix cure for stress, but there are many ways you can reduce stress in your life and improve your overall happiness. We have informational materials to get you started, and UR Medicine Mental Health and Wellness providers can work with you to develop an individual stress management plan. Learn more about the Patient and Family Resources at UR Medicine Mental Health and Wellness.