Sarcoidosis

What is Sarcoidosis?

Sarcoidosis is the growth of inflammatory cells, known as granulomas, that can deposit in different organs of the body. Sarcoidosis can affect your lungs, heart, eyes, skin, kidneys, liver, and other organs. It may be caused by an immune response to an unidentified trigger.

Symptoms include:

Shortness of breath
Abnormally fast or slow heart rhythms
Fatigue, weakness
Dizziness, fainting
Weight loss
Chest pain

The vast majority of patients have a mild form of the disease and might not need treatment. Sarcoidosis is fatal in roughly 5% of patients, with pulmonary and cardiac sarcoidosis the most common causes of death.

Make Referrals to the Pulmonary Center

Call (585) 275-4161

Diagnosing Sarcoidosis

Cardiac sarcoidosis can be difficult to diagnose. Our multidisciplinary team works together to find potential sites outside the heart for biopsy when sarcoidosis is suspected.

In some cases, a biopsy of the heart may be used to make a definite diagnosis. However, since the granulomas are randomly distributed in the heart, a cardiac biopsy may show an abnormality in only 30-50% of patients with cardiac sarcoidosis.

Other tests that are used to help diagnose sarcoidosis include:

EKG and Holter Monitor (to detect abnormally slow or fast rhythms)
Echocardiogram (to evaluate cardiac function)
Cardiac MRI (to look for scarring)
Cardiac PET scan (to look for inflammation)
Biopsy of organs other than the heart

UR Medicine's Treatments for Sarcoidosis

Treatment is needed when there is risk of organ failure and/or if symptoms are affecting a patient’s quality of life. The goal of treatment is to prevent damage to organs. To treat active inflammation, we use immunosuppressive medications, such as:

Steroids
Mycophenolate mofetil
Methotrexate
Azathioprine
Infliximab

Each treatment is tailored to the individual patient.

What Sets Us Apart?

We are the Rochester metropolitan area and surrounding region's only certified WASOG (World Association of Sarcoidosis and Other Granulomatous Disorders) Center of Excellence—one of only 33 programs in the nation and fewer than 50 centers around the world.