Students
Research Interest:
Investigating differential intron sensitivity to PUF60, a gene that is deleted or amplified in developmental syndromes and cancers
Research Interest:
The Effect of Integrator Subunit 11 Mutations on Integrator Function and Neuronal Development
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Investigating the roles of the SF3B1 ULMs in recruiting protein phosphatases for pre-mRNA splicing
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Development of tools and tRNA-based therapeutics for rescue of PTC-derived disease and improved target protein expression
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Investigating the Role of RNA Helicases in Splicing Changes caused by Cancer Associated SF3B1 Mutations
Research Interest:
Identification and Characterization of Transcription Factors Associating with the Integrator Complex
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Visualization, Purification, and Investigation of SIRT6 Nuclear Condensates
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Modeling CDK12 and CDK13 Loss-of-Function to Investigate Their Roles in Alternative Polyadenylation and Neoantigen Expression
Research Interest:
Structure and Function Analysis of a Type III PreQ1 Riboswitch from Escherichia coli
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Pulling the plug on bacteriophage infection: investigating the molecular mechanism of activation of CRISPR-Csx28
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The hormesis effect of glycative stress on the heart during ischemic reperfusion
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Structure and Function Analysis of a Spermidine-Sensing Bacterial Riboswitch
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The Role of the Architectural Transcription Factor HMGN1 in Modulating Inter-nucleosome Interactions
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The Role of Histone Modifications and Variants in Longevity of Rodent Species
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The role of the Type VI CRISPR-Cas accessory protein Csx27 in CRISPR-Cas13 mediated anti-viral immunity
Research Interest:
Defining the roles of 5’UTR length and secondary structure in eukaryotic translation initiation
Research Interest:
Targeted pseudouridylation identifies a novel Ψ-Ψ codon-anticodon pairing in nonsense suppression and translational recoding
Research Interest:
Developing a platform for experimental identification of genetic barriers to horizontal gene transfer in Staphylococcus aureus
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Sustainable Degradation of Marine Plastics using Vegetative and Sporulated 3D-Bioprinted Materials
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High-throughput screening identifies EGLN prolyl hydroxylases as essential determinants of HCMV activation of mitochondrial metabolism
Research Interest:
Examining the Functions of the KDM5 Demethylases in Luminal Lineage Breast Cancer
Research Interest:
Novel CRISPR Screening Pipeline identifies JUNB as an Inflammatory Anti-viral Factor
Research Interest:
In Vitro Selection Identifies Cardiac Cell Targeting RNA Motifs/p>
