Student Researchers

Improving LAIV Efficacy and Understanding Methods Underlying HIV Silencing in Astrocytes

Elucidation of glutathione related dipeptide metabolism in cancer.

Investigating the role of transcriptional pause-release factors in metabolically regulating cell lineage differentiation

Understanding the effects of gestational vitamin B6 deficiency in offspring metabolic health

Understanding the role of the REV-ERB proteins in MYC-driven circadian disruption and cancer. 

Determining the role of epigenetic mark histone H4 lysine K20 tri-methylation (H4K20me3) at active enhancers upon TGF-beta-induced epithelial-to-mesenchymal transition (EMT) in breast cancer.

Understanding the mechanism of pre-mRNA splicing regulation by the long non-coding RNA Neat1.

Regulation of the transcriptional pause and its role in breast cancer.

 The biological mechanisms of aging.

Developing novel thermodynamic parameters for RNA folding stability in simulated cellular environments to improve the accuracy of RNA secondary structure predictions.

Hunger modulation of the feeding initiation circuit in Drosophila melanogaster.

Studying the post-transcriptional modifications of tRNA and their molecular association with neurodevelopment

Restoring Redox/Fyn/c-Cbl (RFC) pathway function as a therapeutic target in non-small cell lung cancers and ovarian cancers, and using transcriptomic and proteomic data to predict additional cancer types of interest

Nucleic Acid Biology, Epigenetics, and Development. My project is focused on the role of H2A.Z in epigenetic inheritance.

The function of lncRNAs in heart development; optimizing techniques to identify direct protein interactions with lncRNAs.

Type VI CRISPR and associated bacterial anti-phage defense systems

Evaluation of single-cell pathway scoring methods and characterization of monocytes in HIV-positive individuals with atherosclerosis.

The role of SUMOylation of HSF1 in the coordination of the heat shock response

Investigating how IgE-mediated allergic stimulation of APCs affects CD4 T cell effector functions.

The interplay between neuroimmune interactions and gestational insults on resulting neurodevelopmental sequelae and disease trajectories. 

Cancer Metabolism and Cancer Microenvironment