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Faculty

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Affiliated Faculty

Jennifer Anolik, M.D., Ph.D.
Jennifer Anolik, M.D., Ph.D.

Anolik Lab

Pathology & Laboratory Medicine
Microbiology & Immunology
Medicine
Research Interest: The role of B cells in the pathophysiology of human systemic lupus and rheumatoid arthritis and the study of new immuno-modulatory treatments

Olga Astapova, M.D., Ph.D.
Olga Astapova, M.D., Ph.D.

Astapova Lab

Medicine
Research Interest:

Mechanisms of androgen actions in the ovary


Laura Calvi, M.D.
Laura Calvi, M.D.

Calvi Lab

Medicine
Pharmacology & Physiology
Neurosurgery
Research Interest: Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow

Deborah Cory-Slechta, Ph.D.
Deborah Cory-Slechta, Ph.D.

Cory-Slechta Lab

Public Health Sciences
Environmental Medicine
Neuroscience
Research Interest: Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.

Lisa DeLouise, Ph.D., M.P.D.
Lisa DeLouise, Ph.D., M.P.D.

DeLouise Lab

Biomedical Engineering
Dermatology
Electrical & Computer Engineering
Research Interest: Understanding the toxicological and biochemical properties of nanomaterial interactions with skin and the immune system; develop in vivo models to investigate nanoparticle skin penetration mechanisms, and develop novel biosensors to improve transdermal drug delivery and tissue engineering approaches.

David Dean, Ph.D.
David Dean, Ph.D.

Dean Lab

Pharmacology & Physiology
Biomedical Engineering
Pediatrics
Research Interest: Molecular mechanisms of gene delivery and development of gene therapies for lung disease

Alison Elder, Ph.D.
Alison Elder, Ph.D.

Elder Lab

Environmental Medicine
Research Interest: Toxicology of inhaled ultrafine particles (UFPs) on the lung, cardiovascular and central nervous system

Fabeha Fazal, Ph.D.
Fabeha Fazal, Ph.D.

Fazal Lab

Pharmacology & Physiology
Pediatrics
Research Interest:

Understanding the pathogenesis of Acute Lung Injury (ALI), a life threatening pulmonary inflammatory condition


Steve Georas, M.D.
Steve Georas, M.D.

Georas Lab

Program for Advanced Immune Bioimaging

Microbiology & Immunology
Environmental Medicine
Medicine
Research Interest:

Defining molecular pathways by which allergens and particulates activate epithelia and dendritic cells in the lung immune system


Todd Jusko, Ph.D.
Todd Jusko, Ph.D.

Rochester Environment and Child Health (REACH) Laboratory

Public Health Sciences
Pediatrics
Environmental Medicine
Research Interest: Environmental and Maternal and Child Health Epidemiology: Defining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.

Kirsi Järvinen-Seppo, M.D., Ph.D.
Kirsi Järvinen-Seppo, M.D., Ph.D.

Järvinen-Seppo Lab

Microbiology & Immunology
Pediatrics
Research Interest:

Development of the infant microbiome and immune system, and how that relates to development of allergic diseases


Matthew Kottmann, M.D.
Matthew Kottmann, M.D.

Kottmann Lab

Medicine
Research Interest: Investigating how novel receptor-based therapeutics modify cytokine production to mitigate lung injury and fibrosis

B. Paige Lawrence, Ph.D.
B. Paige Lawrence, Ph.D.
Director

Lawrence Lab

Environmental Medicine
Microbiology & Immunology
Research Interest:

Delineating mechanisms by which environmental exposures during different life stages alter immune function


Ania Majewska, Ph.D.
Ania Majewska, Ph.D.

Majewska Lab

Neuroscience
Research Interest: Glia-neuron interactions during synaptic plasticity in health and disease

Margot Mayer-Pröschel, Ph.D.
Margot Mayer-Pröschel, Ph.D.

Mayer-Pröschel Lab

Neuroscience
Biomedical Genetics
Research Interest: Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.

Patrick Murphy, Ph.D.
Patrick Murphy, Ph.D.

Patrick Murphy Lab

Biomedical Genetics
Research Interest:

The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.


M. Kerry O'Banion, M.D., Ph.D.
M. Kerry O'Banion, M.D., Ph.D.

O'Banion-Olschowka Labs

Neuroscience
Research Interest: Defining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, as well as late CNS effects following radiation exposure

Thomas O'Connor, Ph.D.
Thomas O'Connor, Ph.D.

Wynne Center for Family Research

Neuroscience
Psychiatry
Obstetrics & Gynecology
Research Interest: The mechanisms by which early stress exposures, including prenatal maternal anxiety and caregiving stress, may persistently shape children's behavioral and biological health

Michael O'Reilly, Ph.D.
Michael O'Reilly, Ph.D.

O'Reilly Lab

Pediatrics
Environmental Medicine
Research Interest:

Defining how an aberrant oxygen environment and oxygen-induced DNA damage signaling alter distal lung development, the host response to respiratory viral infections, and promotes cardiovascular disease later in life


John Onukwufor, Ph.D.
John Onukwufor, Ph.D.

Onukwufor Lab

Mitochondrial Research and Innovation Group

Pharmacology & Physiology
Research Interest:

Elucidate the molecular mechanisms of divalent metal neurotoxicity and mitochondrial dysfunction in Alzheimer's disease pathogenesis


Hae-Ryung Park, Ph.D.
Hae-Ryung Park, Ph.D.

Park Lab

Environmental Medicine
Research Interest:

Identify new targets susceptible to environmental perturbation in relevance with neurodevelopment or neurodegenerative diseases by utilizing functional genetics/genomics (RNAi and CRISPR screens and Next-Generation sequencing), and molecular benchwork. Discover the link between genetic polymorphism of the targets and neurological diseases. Explore novel roles of extracellular vesicles (EV) in receptor signaling and cell communication. Identify EV-encapsulated biomolecules released by the placenta in response to environmental perturbation. Explore the roles of placenta-derived EVs on neurodevelopment or neurodegeneration


Gloria Pryhuber, M.D.
Gloria Pryhuber, M.D.

Pryhuber Lab

Pediatrics
Environmental Medicine
Research Interest:

Chronic lung disease of prematurity and lung development


Christoph Pröschel, Ph.D.
Christoph Pröschel, Ph.D.

Pröschel Lab

Biomedical Genetics
Research Interest:

Using primarily human pluripotent stem cell models, we examine astrocyte development in normal and pathological conditions, the role of astrocytes in modulating response to injury or stress, the role of altered RNA processing and translation in neural development, and the utility of glial precursor cells and their astrocytic progeny for cell transplantation therapy.


Arshad Rahman, Ph.D.
Arshad Rahman, Ph.D.

Arshad Rahman Lab

Pharmacology & Physiology
Pediatrics
Research Interest:

The mechanisms of lung vascular endothelial cell dysfunction in acute lung injury


Irfan Rahman, Ph.D.
Irfan Rahman, Ph.D.

Irfan Rahman Lab

Environmental Medicine
Medicine
Public Health Sciences
Dentistry
Research Interest:

Redox signaling mechanism of Proinflammatory gene expression in pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants


Matthew Rand, Ph.D.
Matthew Rand, Ph.D.

Rand Lab

Environmental Medicine
Research Interest: Mechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.

David Rich, Sc.D., M.P.H.
David Rich, Sc.D., M.P.H.

Rich Lab

Environmental Medicine
Public Health Sciences
Research Interest:

Cardiovascular, respiratory, and perinatal/reproductive health effects of exposure to environmental agents, including ambient air pollution


Jacques Robert, Ph.D.
Jacques Robert, Ph.D.

Robert Lab

Microbiology & Immunology
Environmental Medicine
Research Interest: Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology

Regina Rowe, M.D., Ph.D.
Regina Rowe, M.D., Ph.D.

Rowe Lab

Pediatrics
Research Interest:

Innate cell antiviral responses, allergic inflammation, mucosal/airway immunity, vaccine responses


Souvarish Sarkar, PhD
Souvarish Sarkar, PhD

Sarkar Lab

Environmental Medicine
Neuroscience
Research Interest:

Develop a research program concentrating on identifying genetic modifiers of environmental factors in disease etiology using a combination of Drosophila genetics, cell culture, and rodent models


Marissa Sobolewski-Terry, Ph.D.
Marissa Sobolewski-Terry, Ph.D.

Sobolewski Lab

Environmental Medicine
Neuroscience
Research Interest:

Neurotoxicology, Etiology of neurobehavioral disease, Endocrine dysfunction, Synergistic Toxicity.


Martha Susiarjo, Ph.D.
Martha Susiarjo, Ph.D.

Susiarjo Lab

Environmental Medicine
Research Interest:

Our research program focuses on mechanisms underlying gene environment interaction in pregnancy. We are interested in elucidating how environmental factors influence epigenetic regulation of developmental-relevant genes including imprinted genes, and how exposure modulates maternal-fetal health.


David Topham, Ph.D.
David Topham, Ph.D.

Program for Advanced Immune Bioimaging

Topham Lab

Microbiology & Immunology
Research Interest:

Immune responses to respiratory viruses and experimental vaccines


Andrew Wojtovich, Ph.D.
Andrew Wojtovich, Ph.D.

Wojtovich Lab

Mitochondrial Research and Innovation Group

Pharmacology & Physiology
Anesthesiology and Perioperative Medicine
Research Interest: Optogenetics to study the roles of Reactive Oxygen Species (ROS) in mitochondrial physiology and stress signaling.

Houhui Xia, M.Sc., Ph.D.
Houhui Xia, M.Sc., Ph.D.

Xia Lab

Pharmacology & Physiology
Neuroscience
Research Interest: Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health

Edwin van Wijngaarden, Ph.D., M.Sc.
Edwin van Wijngaarden, Ph.D., M.Sc.

VanWijngaarden Lab

Epidemiology
Public Health Sciences
Environmental Medicine
Research Interest: Environmental and Neurologic Epidemiology: Defining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.