Members

Environmental epidemiology of the effect of air polution on respiratory health


Toxicology of inhaled particulate matter on the lung, cardiovascular, and central nervous systems

Understanding the pathogenesis of Acute Lung Injury (ALI), a life threatening pulmonary inflammatory condition

Delineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.

Defining molecular pathways by which inhaled allergens and particulates activate lung mucosal immunity.


Community engagement, policy, and reporting of research results around environmental health (e.g. healthy housing, lead, microplastics, air quality).

Defining the impact of environmental exposures on immune system development and function, with emphasis on how early life exposures shape health and disease later in life.


Investigates prenatal and early life nutritional and environmental exposures that impact the development of asthma and affect lung growth.

Genetic and environmental susceptibility to developmental lung injury.

Developing and coordinating a wide variety of science education and outreach programs for students (elementary through high school), teachers, and the general community.

Airway epithelial stem cells in chemical inhalation exposures.

Smoking cessation in special populations; technology/web assisted risk behavior intervention; and dissemination of effective interventions to physician practices.


Defining how gene environment interactions shape alveolar lung development and the risk for lung disease over the lifespan.

Biokinetics, Effects, Mechanisms and Risk of Inhaled Particles: Dosimetry; Neuronal Nano-Particle Translocation Nose to Brain; Translation Human to Rodent and vice-versa.

Behavioral medicine and outcomes management include tobacco use and smoking interventions, obesity prevention and exercise.


The mechanisms of lung vascular endothelial cell dysfunction in acute lung injury

Environmental lung diseases COPD and IPF pathogenesis and therapeutic targets: effects of lung cellular mitochondrial dysfunction, senescence, and molecular clock.

Cellular and molecular mechanisms of methylmercury metabolism and toxicity in development of neural and muscular systems using invertebrate, mammalian and human models.

Exploring the mechanisms underlying gene-environment interactions in pregnancy; exploring the role of tryptophan catabolism in pregnancy and on the metabolic health of mother and offspring.

Investigating the influence of exposures (environmental, dietary, dental materials) on oral health and neurodevelopment in children.


