URMC / Labs / Awad Lab / Publications

Recent Publications

1. Ajalik RE
2. Linares I
3. Alenchery RG
4. Zhang VZ
5. Wright TW
6. Miller BL
7. McGrath JL
8. Awad HA
Human Tendon-on-a-Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis.; Advanced healthcare materials. 2024 Nov 15.
1. Kenney HM
2. Chen KL
3. Schnur L
4. Fox JI
5. Wood RW
6. Xing L
7. Ritchlin CT
8. Rahimi H
9. Schwarz EM
10. Awad HA
High-throughput micro-CT analysis identifies sex-dependent biomarkers of erosive arthritis in TNF-Tg mice and differential response to anti-TNF therapy.; PloS one; Vol 19(7), pp. e0305623. 2024 Jul 05.
1. Lee W
2. Tecle N
3. Knapp E
4. Awad H
5. Oh I
Biomechanical Effects of Subtalar Joint Fusion and Medial Ligament Reconstruction in Simulated Progressive Collapsing Foot Deformity.; Foot & ankle international. 2024 Jan 19.
1. Awad H
2. Ajalik R
3. Alenchery R
4. Linares I
5. Wright T
6. Miller B
7. McGrath J
Human tendon-on-a-chip for modeling vascular inflammatory fibrosis.; Research square. 2023 Dec 13.
1. Little D
2. Amadio PC
3. Awad H
4. Cone SG
5. Dyment NA
6. Fisher MB
7. Huang AH
8. Koch DW
9. Kuntz AF
10. Madi R
11. McGilvrey K
12. Schnabel LV
13. Shetye SS
14. Thomopoulos S
15. Zhao C
16. Soslowsky LJ
Preclinical Tendon and Ligament Models: Beyond the 3Rs (Replacement, Reduction, and Refinement) to 5W1H (Why, Who, What, Where, When, How).; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 Aug 12.
1. Lake SP
2. Snedeker JG
3. Wang VM
4. Awad H
5. Screen HRC
6. Thomopoulos S
Guidelines for ex vivo mechanical testing of tendon.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 Jun 13.
1. Alenchery RG
2. Ajalik RE
3. Jerreld K
4. Midekksa F
5. Zhong S
6. Alkatib B
7. Awad HA
PAI-1 mediates TGF-β1 induced myofibroblast activation in tenocytes via mTOR signaling.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 May 04.
1. Kaplan NB
2. Barra MF
3. Jubril A
4. Knapp E
5. Awad H
6. Ginnetti J
Effects of Acetabular Screws on the Initial Stability of Porous Coated Acetabular Implants in Revision Total Hip Arthroplasty.; Cureus; Vol 15(4), pp. e38257. 2023 Apr 28.
1. Sautchuk R
2. Yu C
3. McArthur M
4. Massie C
5. Brookes PS
6. Porter GA
7. Awad H
8. Eliseev RA
ROLE OF THE MITOCHONDRIAL PERMEABILITY TRANSITION IN BONE METABOLISM AND AGING.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2023 Feb 13.
1. Massie C
2. Knapp E
3. Awad HA
4. Berger AJ
Detection of osteoporotic-related bone changes and prediction of distal radius strength using Raman spectra from excised human cadaver finger bones.; Journal of biomechanics; Vol 161, pp. 111852. 2023 Jan 25.
1. Kenney HM
2. Peng Y
3. Chen KL
4. Ajalik R
5. Schnur L
6. Wood RW
7. Schwarz EM
8. Awad HA
A high-throughput semi-automated bone segmentation workflow for murine hindpaw micro-CT datasets.; Bone reports; Vol 16. 2022 Jun.
1. Sautchuk R
2. Kalicharan BH
3. Escalera-Rivera K
4. Jonason JH
5. Porter GA
6. Awad HA
7. Eliseev RA
Transcriptional regulation of Cyclophilin D by BMP/SMAD signaling and its role in osteogenic differentiation.; eLife; Vol 11. 2022 May 30.
1. Ramsdale E
2. Mohamed M
3. Yu V
4. Otto E
5. Juba K
6. Awad H
7. Moorthi K
8. Plumb S
9. Patil A
10. Vogelzang N
11. Dib E
12. Mohile S
Polypharmacy, Potentially Inappropriate Medications, and Drug-Drug Interactions in Vulnerable Older Adults With Advanced Cancer Initiating Cancer Treatment.; The oncologist. 2022 Mar 28.
1. Kallenbach JG
2. Freeberg MAT
3. Abplanalp D
4. Alenchery RG
5. Ajalik RE
6. Muscat S
7. Myers JA
8. Ashton JM
9. Loiselle A
10. Buckley MR
11. van Wijnen AJ
12. Awad HA
Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse.; Scientific reports; Vol 12(1). 2022 Feb 22.
1. McCloskey MC
2. Zhang VZ
3. Ahmad SD
4. Walker S
5. Romanick SS
6. Awad HA
7. McGrath JL
Sourcing cells for in vitro models of human vascular barriers of inflammation.; Frontiers in medical technology; Vol 4, pp. 979768. 2022 Jan 21.
1. Knapp E
2. Awad HA
Cantilever Bending of Murine Femoral Necks.; Journal of visualized experiments : JoVE. 2022 Jan 05.
1. Young M
2. Walsh DJ
3. Masters E
4. Gondil VS
5. Laskey E
6. Klaczko M
7. Awad H
8. McGrath J
9. Schwarz EM
10. Melander C
11. Dunman PM
Identification of Staphylococcus aureus Penicillin Binding Protein 4 (PBP4) Inhibitors.; Antibiotics (Basel, Switzerland); Vol 11(10). 2022 Jan 04.
1. Ajalik RE
2. Alenchery RG
3. Cognetti JS
4. Zhang VZ
5. McGrath JL
6. Miller BL
7. Awad HA
Human Organ-on-a-Chip Microphysiological Systems to Model Musculoskeletal Pathologies and Accelerate Therapeutic Discovery.; Frontiers in bioengineering and biotechnology; Vol 10. 2022.
1. Chen K
2. Massie C
3. Awad HA
4. Berger AJ
Determination of best Raman spectroscopy spatial offsets for transcutaneous bone quality assessments in human hands.; Biomedical optics express; Vol 12(12). 2021 Dec 01.
1. Greenstein AS
2. Chen RE
3. Brown AM
4. Knapp E
5. Roberts A
6. Awad HA
7. Voloshin I
Chondral Damage After Arthroscopic Repair Techniques for Acute Bony Bankart Lesions: A Biomechanical Study.; The American journal of sports medicine. 2021 Jul 08.
1. Greenstein AS
2. Chen RE
3. Knapp E
4. Brown AM
5. Roberts A
6. Awad HA
7. Voloshin I
A Biomechanical, Cadaveric Evaluation of Single- Versus Double-Row Repair Techniques on Stability of Bony Bankart Lesions.; The American journal of sports medicine. 2021 Feb 05.
1. Massie C
2. Knapp E
3. Chen K
4. Berger AJ
5. Awad HA
Improved prediction of femoral fracture toughness in mice by combining standard medical imaging with Raman spectroscopy.; Journal of biomechanics; Vol 116. 2021 Jan 13.
1. Trombetta RP
2. Knapp EK
3. Awad HA
A Mouse Femoral Ostectomy Model to Assess Bone Graft Substitutes.; Methods in molecular biology (Clifton, N.J.); Vol 2230. 2021.
1. Masters EA
2. Muthukrishnan G
3. Ho L
4. Gill AL
5. de Mesy Bentley KL
6. Galloway CA
7. McGrath JL
8. Awad HA
9. Gill SR
10. Schwarz EM
Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis.; Frontiers in microbiology; Vol 12. 2021.
1. Best KT
2. Nichols AEC
3. Knapp E
4. Hammert WC
5. Ketonis C
6. Jonason JH
7. Awad HA
8. Loiselle AE
NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival.; Science signaling; Vol 13(658). 2020 Nov 17.
1. Masters EA
2. de Mesy Bentley KL
3. Gill AL
4. Hao SP
5. Galloway CA
6. Salminen AT
7. Guy DR
8. McGrath JL
9. Awad HA
10. Gill SR
11. Schwarz EM
Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice.; PLoS pathogens; Vol 16(10). 2020 Oct 22.
1. Hollenberg AM
2. Smith CO
3. Shum LC
4. Awad H
5. Eliseev RA
Lactate Dehydrogenase Inhibition with Oxamate Exerts Bone Anabolic Effect.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020 Jul 30.
1. Dyment NA
2. Barrett JG
3. Awad HA
4. Bautista CA
5. Banes AJ
6. Butler DL
A brief history of tendon and ligament bioreactors: Impact and future prospects.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2020 Jun 24.
1. MacDonald A
2. Ciufo D
3. Vess E
4. Knapp E
5. Awad HA
6. Ketz JP
7. Flemister AS
8. Oh I
Peritalar Kinematics With Combined Deltoid-Spring Ligament Reconstruction in Simulated Advanced Adult Acquired Flatfoot Deformity.; Foot & ankle international. 2020 Jun 04.
1. Best KT
2. Studentsova V
3. Ackerman JE
4. Nichols AEC
5. Myers M
6. Cobb J
7. Knapp E
8. Awad HA
9. Loiselle AE
Effects of Tamoxifen on Tendon Homeostasis and Healing: Considerations for the use of Tamoxifen-Inducible Mouse Models.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2020 Jun 02.
1. Pelled G
2. Lieber R
3. Avalos P
4. Cohn-Yakubovich D
5. Tawackoli W
6. Roth J
7. Knapp E
8. Schwarz EM
9. Awad HA
10. Gazit D
11. Gazit Z
Teriparatide (rPTH1-34) enhances bone allograft integration in a clinically relevant pig model of segmental mandibulectomy.; Journal of tissue engineering and regenerative medicine. 2020 Jun 01.
1. Vokes J
2. Obudzinski S
3. Knapp E
4. O'Malley S
5. Awad H
6. O'Malley N
The Effects of Splitting an Above Elbow Cast: A biomechanical study.; Injury. 2020 May 23.
1. Shares BH
2. Smith CO
3. Sheu TJ
4. Sautchuk R
5. Schilling K
6. Shum LC
7. Paine A
8. Huber A
9. Gira E
10. Brown E
11. Awad H
12. Eliseev RA
Inhibition of the mitochondrial permeability transition improves bone fracture repair.; Bone. 2020 Apr 28.
1. O'Keefe RJ
2. Tuan RS
3. Lane NE
4. Awad HA
5. Barry F
6. Bunnell BA
7. Colnot C
8. Drake MT
9. Drissi H
10. Dyment NA
11. Fortier LA
12. Guldberg RE
13. Kandel R
14. Little DG
15. Marshall MF
16. Mao JJ
17. Nakamura N
18. Proffen BL
19. Rodeo SA
20. Rosen V
21. Thomopoulos S
22. Schwarz EM
23. Serra R
American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies - Secondary Publication.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 38(3). 2020 Mar.
1. Chen RE
2. Soin SP
3. El-Shaar R
4. Nicandri GT
5. Awad HA
6. Maloney MD
7. Voloshin I
What Regions of the Distal Clavicle Have the Greatest Bone Mineral Density and Cortical Thickness? A Cadaveric Study.; Clinical orthopaedics and related research; Vol 477(12). 2019 Dec.
1. O'Keefe RJ
2. Tuan RS
3. Lane NE
4. Barry F
5. Bunnell BA
6. Colnot C
7. Drake MT
8. Drissi H
9. Fortier LA
10. Guldberg RE
11. Little DG
12. Marshall MF
13. Mao JJ
14. Nakamura N
15. Robey PG
16. Rosen V
17. Rowe DW
18. Schwarz EM
American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2019 Sep 23.
1. Chen RE
2. Soin SP
3. El-Shaar R
4. Nicandri GT
5. Awad HA
6. Maloney MD
7. Voloshin I
What Regions of the Distal Clavicle Have the Greatest Bone Mineral Density and Cortical Thickness? A Cadaveric Study.; Clinical orthopaedics and related research. 2019 Aug 29.
1. Freeberg MAT
2. Easa A
3. Lillis JA
4. Benoit DSW
5. van Wijnen AJ
6. Awad HA
Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019 Aug 19.
1. Best KT
2. Lee FK
3. Knapp E
4. Awad HA
5. Loiselle AE
Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing.; Scientific reports; Vol 9(1). 2019 Jul 29.
1. Trombetta RP
2. de Mesy Bentley KL
3. Schwarz EM
4. Kate SL
5. Awad HA
A murine femoral ostectomy model with hardware exchange to assess antibiotic-impregnated spacers for implant-associated osteomyelitis.; European cells & materials; Vol 37. 2019 Jun 27.
1. Masters EA
2. Salminen AT
3. Begolo S
4. Luke EN
5. Barrett S
6. Overby CT
7. Gill AL
8. de Mesy Bentley KL
9. Awad HA
10. Gill SR
11. Schwarz EM
12. McGrath JL
An in vitro platform for elucidating the molecular genetics of S. aureus invasion of the osteocyte lacuno-canalicular network during chronic osteomyelitis.; Nanomedicine : nanotechnology, biology, and medicine. 2019 Jun 24.
1. Feigenson M
2. Jonason JH
3. Shen J
4. Loiselle AE
5. Awad HA
6. O'Keefe RJ
Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair.; Annals of biomedical engineering. 2019 Apr 12.
1. Trombetta RP
2. Ninomiya MJ
3. El-Atawneh IM
4. Knapp EK
5. de Mesy Bentley KL
6. Dunman PM
7. Schwarz EM
8. Kates SL
9. Awad HA
Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associated Osteomyelitis.; Pharmaceutics; Vol 11(2). 2019 Feb 22.
1. Chen RE
2. Soin SP
3. El-Shaar R
4. Awad HA
5. Maloney MD
6. Voloshin I
Reconstruction of the Superior Glenoid Labrum With Biceps Tendon Autograft: A Cadaveric Biomechanical Study.; Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association; Vol 35(2). 2019 Feb.
1. Masters EA
2. Trombetta RP
3. de Mesy Bentley KL
4. Boyce BF
5. Gill AL
6. Gill SR
7. Nishitani K
8. Ishikawa M
9. Morita Y
10. Ito H
11. Bello-Irizarry SN
12. Ninomiya M
13. Brodell JD
14. Lee CC
15. Hao SP
16. Oh I
17. Xie C
18. Awad HA
19. Daiss JL
20. Owen JR
21. Kates SL
22. Schwarz EM
23. Muthukrishnan G
Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".; Bone research; Vol 7. 2019.
1. Trombetta RP
2. Dunman PM
3. Schwarz EM
4. Kates SL
5. Awad HA
A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants.; mSphere; Vol 3(5). 2018 Oct 31.
1. Shu C
2. Chen K
3. Lynch M
4. Maher JR
5. Awad HA
6. Berger AJ
Spatially offset Raman spectroscopy for in vivo bone strength prediction.; Biomedical optics express; Vol 9(10). 2018 Oct 01.
1. Childs S
2. McVicker Z
3. Trombetta R
4. Awad H
5. Elfar J
6. Giordano B
Patient-Specific 3-Dimensional Modeling and Its Use for Preoperative Counseling of Patients Undergoing Hip Arthroscopy.; Orthopaedic journal of sports medicine; Vol 6(9). 2018 Sep.
1. Schott EM
2. Farnsworth CW
3. Grier A
4. Lillis JA
5. Soniwala S
6. Dadourian GH
7. Bell RD
8. Doolittle ML
9. Villani DA
10. Awad H
11. Ketz JP
12. Kamal F
13. Ackert-Bicknell C
14. Ashton JM
15. Gill SR
16. Mooney RA
17. Zuscik MJ
Targeting the gut microbiome to treat the osteoarthritis of obesity.; JCI insight; Vol 3(8). 2018 Apr 19.
1. Freeberg MAT
2. Farhat YM
3. Easa A
4. Kallenbach JG
5. Malcolm DW
6. Buckley MR
7. Benoit DSW
8. Awad HA
Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.; Scientific reports; Vol 8(1). 2018 Apr 11.