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Scientists Developing Microchips with Brain and Lung Tissue to Study Viral Neuroinflammation

Wednesday, October 16, 2024

Researchers will use tissue-on-chip technology as a new way to explore the relationship between the lungs and brain. Scientists are developing advanced tools to understand and treat neurological symptoms such as brain fog associated with respiratory diseases like influenza. The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the US Department of Health and Human Services (HHS), awarded a three-year contract to researchers at the University of Rochester to develop a technology to model respiratory disease effects on the brain and test therapeutic drugs to prevent and treat symptoms. The base-year is funded at $2.4 million with two option years which, if fully funded, would total $7.1 million.

New NIH-funded Center Could Soon Reduce the Need for Pharmaceutical Trials on Animals

Tuesday, January 9, 2024

Rochester is one of four NIH-sponsored centers that aims to produce tissue-on-chip devices as FDA-qualified drug development tools. The center aims to develop five Food and Drug Administration–qualified drug development tools related to study barrier functions in disease—interfaces in tissue that are critical for the progression of infection, cancer, and many autoimmune disorders.