Lab Members
Lab Members
Principal Investigator
Research Interest: Regulation of pre-mRNA splicing and polyadenylation in healthy and diseased states; the contribution of RNA processing to cancer biology; effects of small molecule drugs on RNA processing and gene expression.
Research Staff
Graduate Students
Research Interest:
Investigating differential intron sensitivity to PUF60, a gene that is deleted or amplified in developmental syndromes and cancers
Research Interest:
Investigating the Role of RNA Helicases in Splicing Changes caused by Cancer Associated SF3B1 Mutations
Research Interest:
Modeling the effects of cancer-associated spliceosome mutations and identifying driving intronic features using deep-learning neural networks
Research Interest:
Modeling CDK12 and CDK13 Loss-of-Function to Investigate Their Roles in Alternative Polyadenylation and Neoantigen Expression