URMC / Labs / Boutz Lab / Publications Recent Publications Boutz PL Putting a finger on histidine methylation.; Genes & development; Vol 37(15-16), pp. 675-677. 2023 Sep 06. Insco MLAbraham BJDubbury SJKaltheuner IHDust SWu CChen KYLiu DBellaousov SCox AMMartin BJEZhang TLudwig CGFabo TModhurima REsgdaille DEHenriques TBrown KMChanock SJGeyer MAdelman KSharp PAYoung RABoutz PLZon LI Oncogenic CDK13 mutations impede nuclear RNA surveillance.; Science (New York, N.Y.); Vol 380(6642), pp. eabn7625. 2023 Apr 21. Galardi JWBela VNJeffery NHe XGlasser ELoerch SJenkins JLPulvino MJBoutz PLKielkopf CL A UHM - ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.; The Journal of biological chemistry. 2022 Jun 30. Tan ZWFei GPaulo JABellaousov SMartin SESDuveau DYThomas CJGygi SPBoutz PLWalker S O-GlcNAc regulates gene expression by controlling detained intron splicing.; Nucleic acids research; Vol 48(10), pp. 5656-5669. 2020 Jun 04. Martin SESTan ZWItkonen HMDuveau DYPaulo JAJanetzko JBoutz PLTörk LMoss FAThomas CJGygi SPLazarus MBWalker S Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.; Journal of the American Chemical Society. 2018 Oct 04. Murphy PAButty VLBoutz PLBegum SKimble ALSharp PABurge CBHynes RO Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow.; eLife; Vol 7. 2018 Jan 02. Dubbury SJBoutz PLSharp PA CDK12 regulates DNA repair genes by suppressing intronic polyadenylation.; Nature; Vol 564(7734). 2018 Jan. Braun CJStanciu MBoutz PLPatterson JCCalligaris DHiguchi FNeupane RFenoglio SCahill DPWakimoto HAgar NYRYaffe MBSharp PAHemann MTLees JA Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.; Cancer cell; Vol 32(4). 2017 Jan 09. Boutz PLBhutkar ASharp PA Detained introns are a novel, widespread class of post-transcriptionally spliced introns.; Genes & development; Vol 29(1). 2015 Jan 01. Jangi MBoutz PLPaul PSharp PA Rbfox2 controls autoregulation in RNA-binding protein networks.; Genes & development; Vol 28(6). 2014 Mar 15. Boutz PLStoilov PLi QLin CHChawla GOstrow KShiue LAres MBlack DL A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.; Genes & development; Vol 21(13). 2007 Jul 01. Boutz PLChawla GStoilov PBlack DL MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development.; Genes & development; Vol 21(1). 2007 Jan 01. Underwood JGBoutz PLDougherty JDStoilov PBlack DL Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals.; Molecular and cellular biology; Vol 25(22). 2005 Nov. Amir-Ahmady BBoutz PLMarkovtsov VPhillips MLBlack DL Exon repression by polypyrimidine tract binding protein.; RNA (New York, N.Y.); Vol 11(5). 2005 May. Biswas SKBoutz PLNayak DP Influenza virus nucleoprotein interacts with influenza virus polymerase proteins.; Journal of virology; Vol 72(7), pp. 5493-501. 1998 Jul. Panyutich AShi JBoutz PLZhao CGanz T Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins.; Infection and immunity; Vol 65(3), pp. 978-85. 1997 Mar.