URMC / Labs / Ermolenko Lab / Publications Recent Publications De Zoysa THauke ACIyer NRMarcus EOstrowski SMStegemann FErmolenko DNFay JCPhizicky EM A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay.; PLoS genetics; Vol 20(1), pp. e1011146. 2024 Jan 31. Das ABao CErmolenko DN Comparing FRET Pairs that Report on Intersubunit Rotation in Bacterial Ribosomes.; Journal of molecular biology; Vol 435(15), pp. 168185. 2023 Jun 20. Das ABao CErmolenko DN Comparing FRET pairs that report on intersubunit rotation in bacterial ribosomes.; bioRxiv : the preprint server for biology. 2023 May 09. Das AAdiletta NErmolenko DN Interplay between Inter-Subunit Rotation of the Ribosome and Binding of Translational GTPases.; International journal of molecular sciences; Vol 24(8). 2023 Apr 07. Bao CZhu MNykonchuk IWakabayashi HMathews DHErmolenko DN Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation.; Nature communications; Vol 13(1). 2022 Feb 21. Lai WCZhu MBelinite MBallard GMathews DHErmolenko DN Intrinsically unstructured sequences in the mRNA 3' UTR reduce the ability of poly(A) tail to enhance translation.; Journal of molecular biology. 2022 Jan 08. Bao CErmolenko DN Ribosome as a Translocase and Helicase.; Biochemistry. Biokhimiia; Vol 86(8). 2021 Aug. Ermolenko DNMathews DH Making ends meet: New functions of mRNA secondary structure.; Wiley interdisciplinary reviews. RNA. 2020 Jun 29. Wakabayashi HWarnasooriya CErmolenko DN Extending the Spacing between the Shine-Dalgarno Sequence and P-Site Codon Reduces the Rate of mRNA Translocation.; Journal of molecular biology. 2020 Jun 13. Warnasooriya CFeeney CFLaird KMErmolenko DNKielkopf CL A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.; Nucleic acids research; Vol 48(10). 2020 Jun 04. Bao CLoerch SLing CKorostelev AAGrigorieff NErmolenko DN mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.; eLife; Vol 9. 2020 May 19. Ermolenko DNWhitford PC Experimental and computational techniques for studying structural dynamics and function of RNA.; Methods (San Diego, Calif.); Vol 162-163. 2019 Jun 01. Lai WCKayedkhordeh MCornell EVFarah EBellaousov SRietmeijer RSalsi EMathews DHErmolenko DN mRNAs and lncRNAs intrinsically form secondary structures with short end-to-end distances.; Nature communications; Vol 9(1). 2018 Oct 18. Warnasooriya CLing CBelashov IASalim MWedekind JEErmolenko DN Observation of preQ1-II riboswitch dynamics using single-molecule FRET.; RNA biology. 2018 Oct 17. Lai CWErmolenko DN Ensemble and single-molecule FRET studies of protein synthesis.; Methods (San Diego, Calif.). 2017 Dec 13. Ling CErmolenko DN Caught on Camera: Intermediates of Ribosome Recycling.; Structure (London, England : 1993); Vol 24(12). 2016 Dec 06. Salsi EFarah EErmolenko DN EF-G Activation by Phosphate Analogs.; Journal of molecular biology; Vol 428(10 Pt B). 2016 May 22. Ling CErmolenko DN Structural insights into ribosome translocation.; Wiley interdisciplinary reviews. RNA. 2016 Apr 27. Agrawal AASalsi EChatrikhi RHenderson SJenkins JLGreen MRErmolenko DNKielkopf CL An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.; Nature communications; Vol 7. 2016. Ling CErmolenko DN Initiation factor 2 stabilizes the ribosome in a semirotated conformation.; Proceedings of the National Academy of Sciences of the United States of America; Vol 112(52). 2015 Dec 29. Ling CErmolenko DN Ribosome subunit joining frozen in time.; Structure (London, England : 1993); Vol 23(6). 2015 Jun 2. Salsi EFarah ENetter ZDann JErmolenko DN Movement of elongation factor G between compact and extended conformations.; Journal of molecular biology; Vol 427(2). 2015 Jan 30. Salsi EFarah EDann JErmolenko DN Following movement of domain IV of elongation factor G during ribosomal translocation.; Proceedings of the National Academy of Sciences of the United States of America; Vol 111(42). 2014 Oct 21. Kurosaki TLi WHoque MPopp MWErmolenko DNTian BMaquat LE A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.; Genes & development; Vol 28(17). 2014 Sep 1. Brilot AFKorostelev AAErmolenko DNGrigorieff N Structure of the ribosome with elongation factor G trapped in the pretranslocation state.; Proceedings of the National Academy of Sciences of the United States of America; Vol 110(52). 2013 Dec 24. Azpurua JKe ZChen IXZhang QErmolenko DNZhang ZDGorbunova VSeluanov A Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage.; Proceedings of the National Academy of Sciences of the United States of America; Vol 110(43). 2013 Oct 22. Svidritskiy ELing CErmolenko DNKorostelev AA Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.; Proceedings of the National Academy of Sciences of the United States of America; Vol 110(30). 2013 Jul 23. Ermolenko DNCornish PVHa TNoller HF Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation.; RNA (New York, N.Y.); Vol 19(2). 2013 Feb. Rudenko MIHolmes MRErmolenko DNLunt EJGerhardt SNoller HFDeamer DWHawkins ASchmidt H Controlled gating and electrical detection of single 50S ribosomal subunits through a solid-state nanopore in a microfluidic chip.; Biosensors & bioelectronics; Vol 29(1). 2011 Nov 15. Ermolenko DNNoller HF mRNA translocation occurs during the second step of ribosomal intersubunit rotation.; Nature structural & molecular biology; Vol 18(4). 2011 Apr. Cornish PVErmolenko DNStaple DWHoang LHickerson RPNoller HFHa T Following movement of the L1 stalk between three functional states in single ribosomes.; Proceedings of the National Academy of Sciences of the United States of America; Vol 106(8). 2009 Feb 24. Korostelev AErmolenko DNNoller HF Structural dynamics of the ribosome.; Current opinion in chemical biology; Vol 12(6). 2008 Dec. Cornish PVErmolenko DNNoller HFHa T Spontaneous intersubunit rotation in single ribosomes.; Molecular cell; Vol 30(5). 2008 Jun 6. Spiegel PCErmolenko DNNoller HF Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome.; RNA (New York, N.Y.); Vol 13(9). 2007 Sep. Ermolenko DNMajumdar ZKHickerson RPSpiegel PCClegg RMNoller HF Observation of intersubunit movement of the ribosome in solution using FRET.; Journal of molecular biology; Vol 370(3). 2007 Jul 13. Ermolenko DNSpiegel PCMajumdar ZKHickerson RPClegg RMNoller HF The antibiotic viomycin traps the ribosome in an intermediate state of translocation.; Nature structural & molecular biology; Vol 14(6). 2007 Jun. Ermolenko DNDangi BGvritishvili AGronenborn AMMakhatadze GI Elimination of the C-cap in ubiquitin - structure, dynamics and thermodynamic consequences.; Biophysical chemistry; Vol 126(1-3). 2007 Mar. Ermolenko DNZherdev AVDzantiev BB Horseradish peroxidase renaturation is less efficient at lower protein concentrations.; Protein and peptide letters; Vol 12(7). 2005 Oct. Ermolenko DNZherdev AVDzantiev BB Antibodies as specific chaperones.; Biochemistry. Biokhimii︠a︡; Vol 69(11). 2004 Nov. Bezsudnova EIuZherdev AVErmolenko DNIakovleva IVSviridov VVPopov VODzantiev BB [Peroxidase refolding in the presence of specific antibodies].; Prikladnaia biokhimiia i mikrobiologiia; Vol 39(5). 2003 Sep. Ermolenko DNRichardson JMMakhatadze GI Noncharged amino acid residues at the solvent-exposed positions in the middle and at the C terminus of the alpha-helix have the same helical propensity.; Protein science : a publication of the Protein Society; Vol 12(6). 2003 Jun. Makhatadze GILoladze VVErmolenko DNChen XThomas ST Contribution of surface salt bridges to protein stability: guidelines for protein engineering.; Journal of molecular biology; Vol 327(5). 2003 Apr 11. Ermolenko DNMakhatadze GI Bacterial cold-shock proteins.; Cellular and molecular life sciences : CMLS; Vol 59(11). 2002 Nov. Ermolenko DNThomas STAurora RGronenborn AMMakhatadze GI Hydrophobic interactions at the Ccap position of the C-capping motif of alpha-helices.; Journal of molecular biology; Vol 322(1). 2002 Sep 6. Loladze VVErmolenko DNMakhatadze GI Thermodynamic consequences of burial of polar and non-polar amino acid residues in the protein interior.; Journal of molecular biology; Vol 320(2). 2002 Jul 5. Ermolenko DNZherdev AVDzantiev BBPopov VO Antiperoxidase antibodies enhance refolding of horseradish peroxidase.; Biochemical and biophysical research communications; Vol 291(4). 2002 Mar 8. Loladze VVErmolenko DNMakhatadze GI Heat capacity changes upon burial of polar and nonpolar groups in proteins.; Protein science : a publication of the Protein Society; Vol 10(7). 2001 Jul.