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URMC / Labs / Mohile Lab / Clinical Trials

Clinical Trials

A Pilot Randomized Controlled Trial (RCT) of a Dyadic Life Review Intervention for Older Patients with Advanced Cancer) and their Caregivers

Lead Researcher: Lee Kehoe

A Pilot Randomized Controlled Trial of a Patient-Centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists

Lead Researcher: Kah poh Loh

The objective of this study is to conduct a pilot randomized trial to evaluate the preliminary efficacy of the UR-GOAL tool vs. usual care in improving shared decision making and communication between 100 older patients with AML and their oncologists.

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A Pilot Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms

Lead Researcher: Kah poh Loh

This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.

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A Single Arm Pilot Trial of a Social Network Intervention (SONATA) for Older Patients on Oral Anticancer Treatments and Their Network Members

Lead Researcher: Kah Poh Loh

A Telehealth Advance Care Planning Intervention for Older patients with Myeloid Malignancies: A Pilot Randomized Controlled Trial

Lead Researcher: Kah Poh Loh

Decreasing Polypharmacy in Older Adults with Curable Cancers: a Pilot Cluster-Randomized Trial

Lead Researcher: Erika Ramsdale

Enhancing Triadic Communication About Cognition for Older Adults with Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision 

Lead Researcher: Allison Magnuson

Patient-Centered Communication to Build Trust

Lead Researcher: Nikesha Gilmore

Funded By: Wilmot Pilot Grant from the Community Outreach and Engagement Office

Patient-centered communication is modifiable and a key component to the delivery of high-quality equitable care. Patient-centered communication involves information exchange, fostering healing relationships, managing uncertainty, making decisions, managing emotions, enabling self-management, trust, mutual understanding, and caring. We are interested in understanding the relationship between trust in the medical system and patient-centered communication in older patients with cancer undergoing cancer treatment and their caregivers. The long-term goal of this study is to determine ways to improve the relationship between diverse groups of older patients with cancer and their caregivers with their health care providers.

Pathways to Resilience of Social Networks of Older Adults with Advanced Cancer

Lead Researcher: Supriya Mohile