Harris Lab
Welcome to the Harris Lab
?There has been a long-standing belief that supplementation with antioxidants could prevent or treat cancer. However, results of large-scale clinical trials have proven the opposite: supplementation with antioxidants promote, rather than prevent, cancer. The Harris Lab at the University of Rochester Medical Center and Wilmot Cancer Institute focuses on uncovering the various roles of antioxidants in cancer by using in vivo mouse modeling approaches and high-throughput pharmacologic screening techniques.
Isaac S. Harris, Ph.D.
Principal Investigator
- Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.; JCI insight; Vol 9(13). 2024 May 30.
- United They Stand, Divided They Fall.; Cell metabolism; Vol 30(4). 2019 Oct 01.
- Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.; Cell metabolism; Vol 29(5). 2019 May 07.
- Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.; Proceedings of the National Academy of Sciences of the United States of America; Vol 115(27). 2018 Jul 03.
Contact Us
Harris Lab
Wilmot Cancer Institute
KMRB G.9872
415 Elmwood Avenue
Rochester, NY 14642