Welcome to the Keane Vision & Psychosis Lab

Our brains are faced with the formidable challenge of having to parse and make sense of a kaleidoscope of incoming visual information.  Healthy people segment scenes effortlessly but people with psychosis exhibit specific impairments linked to diagnosis, symptom severity, premorbid functioning, and age of onset.  A major goal of the lab is to harness tools of behavioral psychophysics, eye tracking, and functional neuroimaging to understand the neural and information processes that underlie visual object perception, both in healthy and psychotic populations. 

Selected Publications

1. Keane BP, Abrham YT, Cole MW, Johnson BA, Hu B, Cocuzza CV. Functional dysconnectivity of visual and somatomotor networks yields a simple and robust biomarker for psychosis. 2014. Mol Psychiatry. Published online 2024:1-9. doi:10.1038/s41380-024-02767-3
2. Keane, B.P., Barch, D.M., Mill, R.D., Silverstein, S.M., Krekelberg, B., Cole, M.W., 2021. Brain network mechanisms of visual shape completion. Neuroimage 236, 118069.
3. Keane B.P., Paterno D., Kastner S., Krekelberg B., Silverstein S.M., 2019. Intact illusory contour formation but equivalently impaired visual shape completion in first- and later-episode schizophrenia.. Journal of Abnormal Psychology 128(1)
4. Keane, B.P., Cruz, L.N., Paterno, D., Silverstein, S.M., 2018. Self-reported visual perceptual abnormalities are strongly associated with core clinical features in psychotic disorders. Frontiers in Psychiatry 9, 1–10.
5. Keane, B.P., Paterno, D., Kastner, S., Silverstein, S.M., 2016. Visual integration dysfunction in schizophrenia arises by the first psychotic episode and worsens with illness duration. J Abnorm Psychol 125, 543–549.
6. Keane, B.P., Silverstein, S.M., Wang, Y., Papathomas, T.V., 2013. Reduced depth inversion illusions in schizophrenia are state-specific and occur for multiple object types and viewing conditions. J Abnorm Psychol 122, 506–512.

Visit my Google Scholar Page.

We are recruiting study participants! We also occasionally have paid and volunteer research positions available.
 Please click on the link below for details.