Lab Members
Lab Members
Principal Investigator
Research Interest: Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.
Faculty
Research Interest:
X-ray crystallography and cryo-electron microscopy analysis of RNA and protein-RNA complexes
Research Staff
Graduate Students
Research Interest:
Investigating the roles of the SF3B1 ULMs in recruiting protein phosphatases for pre-mRNA splicing
Research Interest:
A UHM-ULM interface contributes to the pre-mRNA splicing functions of U2AF2 and SF3B1
Research Interest:
Structural Investigation of Early Splicing Factor Complexes
