Lab Members
Lab Members
Principal Investigator

Research Interest: Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.
Faculty

Research Interest:
X-ray crystallography and cryo-electron microscopy analysis of RNA and protein-RNA complexes
Research Staff
Graduate Students

Research Interest:
Investigating the roles of the SF3B1 ULMs in recruiting protein phosphatases for pre-mRNA splicing

Research Interest:
A UHM-ULM interface contributes to the pre-mRNA splicing functions of U2AF2 and SF3B1

Research Interest:
Investigating Dynamic Exchanges Among Pre-mRNA Splicing Factor Complexes