URMC / Labs / Kottmann Lab / Publications

Publications

1. Lin X
2. Bai H
3. Barravecchia M
4. Norman R
5. Schiralli Lester GM
6. Kottmann RM
7. Leonard A
8. Rahman A
9. Young JL
10. Dean DA
Occludin Is Essential to Maintain Normal Alveolar Barrier Integrity and Its Protective Role During ARDS Progression.; International journal of molecular sciences; Vol 25(21). 2024 Oct 29.
1. Nagel DJ
2. Rackow AR
3. Ku WY
4. Bell TJ
5. Sime PJ
6. Kottmann RM
Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation and Fibrosis; Potential Implications for Idiopathic Pulmonary Fibrosis.; Cells; Vol 11(16). 2022 Aug 16.
1. Bell TJ
2. Nagel DJ
3. Woeller CF
4. Kottmann RM
Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH.; PloS one; Vol 17(7), pp. e0271608. 2022 Jul 28.
1. Kalininskiy A
2. Rackow AR
3. Nagel D
4. Croft D
5. McGrane-Minton H
6. Kottmann RM
Association between weight loss and mortality in idiopathic pulmonary fibrosis.; Respiratory research; Vol 23(1), pp. 377. 2022 Jan 24.
1. Rackow AR
2. Nagel DJ
3. Zapas G
4. Clough RS
5. Sime PJ
6. Kottmann RM
The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity.; International journal of molecular sciences; Vol 23(19). 2022 Jan 08.
1. Rackow AR
2. Judge JL
3. Woller CF
4. Sime PJ
5. Kottmann RM
miR-338-3p Blocks TGFβ-Induced Myofibroblast Differentiation through the Induction of PTEN.; American journal of physiology. Lung cellular and molecular physiology. 2022 Jan 05.
1. Croft DP
2. Burton DS
3. Nagel DJ
4. Bhattacharya S
5. Falsey AR
6. Georas SN
7. Hopke PK
8. Johnston CJ
9. Kottmann RM
10. Litonjua AA
11. Mariani TJ
12. Rich DQ
13. Thevenet-Morrison K
14. Thurston SW
15. Utell MJ
16. McCall MN
The effect of air pollution on the transcriptomics of the immune response to respiratory infection.; Scientific reports; Vol 11(1). 2021 Sep 30.
1. Rackow AR
2. Nagel DJ
3. McCarthy C
4. Judge J
5. Lacy S
6. Freeberg MAT
7. Thatcher TH
8. Kottmann RM
9. Sime PJ
The Self-fulfilling Prophecy of Pulmonary Fibrosis: A Selective Inspection of Pathologic Signaling Loops.; The European respiratory journal. 2020 Sep 17.
1. Wu EK
2. Ambrosini RD
3. Kottmann RM
4. Ritchlin CT
5. Schwarz EM
6. Rahimi H
Reinterpreting Evidence of Rheumatoid Arthritis-Associated Interstitial Lung Disease to Understand Etiology.; Current rheumatology reviews. 2019 Jan 15.
1. Lachant DJ
2. Croft DP
3. McGrane Minton H
4. Hardy DJ
5. Prasad P
6. Kottmann RM
The clinical impact of pneumocystis and viral PCR testing on bronchoalveolar lavage in immunosuppressed patients.; Respiratory medicine; Vol 145. 2018 Dec.
1. Judge JL
2. Nagel DJ
3. Owens KM
4. Rackow A
5. Phipps RP
6. Sime PJ
7. Kottmann RM
Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol.; PloS one; Vol 13(5). 2018.
1. Lachant DJ
2. Croft DP
3. McGrane Minton H
4. Prasad P
5. Kottmann RM
Nasopharyngeal viral PCR in immunosuppressed patients and its association with virus detection in bronchoalveolar lavage by PCR.; Respirology (Carlton, Vic.); Vol 22(6). 2017 Aug.
1. Jackson TC
2. Zhang YV
3. Sime PJ
4. Phipps RP
5. Kottmann RM
Development of an accurate and sensitive method for lactate analysis in exhaled breath condensate by LC MS/MS.; Journal of chromatography. B, Analytical technologies in the biomedical and life sciences; Vol 1061-1062. 2017 Jul 24.
1. Judge JL
2. Lacy SH
3. Ku WY
4. Owens KM
5. Hernady E
6. Thatcher TH
7. Williams JP
8. Phipps RP
9. Sime PJ
10. Kottmann RM
The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis.; Radiation research. 2017 May 02.
1. Yee M
2. Domm W
3. Gelein R
4. Bentley KL
5. Kottmann RM
6. Sime PJ
7. Lawrence BP
8. O'Reilly MA
Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.; American journal of respiratory cell and molecular biology; Vol 56(4). 2017 Apr.
1. Kottmann RM
2. Trawick E
3. Judge JL
4. Wahl LA
5. Epa AP
6. Owens KM
7. Thatcher TH
8. Phipps RP
9. Sime PJ
Pharmacologic inhibition of lactate production prevents myofibroblast differentiation.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(11). 2015 Dec 1.
1. Judge JL
2. Owens KM
3. Pollock SJ
4. Woeller CF
5. Thatcher TH
6. Williams JP
7. Phipps RP
8. Sime PJ
9. Kottmann RM
Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(8). 2015 Oct 15.
1. Croasdell A
2. Thatcher TH
3. Kottmann RM
4. Colas RA
5. Dalli J
6. Serhan CN
7. Sime PJ
8. Phipps RP
Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(8). 2015 Oct 15.
1. Kottmann RM
2. Sharp J
3. Owens K
4. Salzman P
5. Xiao GQ
6. Phipps RP
7. Sime PJ
8. Brown EB
9. Perry SW
Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung.; Respiratory research; Vol 16(1). 2015 May 27.
1. Jones KM
2. Randtke EA
3. Howison CM
4. Cárdenas-Rodríguez J
5. Sime PJ
6. Kottmann MR
7. Pagel MD
Measuring extracellular pH in a lung fibrosis model with acidoCEST MRI.; Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging; Vol 17(2). 2015 Apr.
1. Epa AP
2. Thatcher TH
3. Pollock SJ
4. Wahl LA
5. Lyda E
6. Kottmann RM
7. Phipps RP
8. Sime PJ
Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2.; PloS one; Vol 10(8). 2015.
1. Olsen KC
2. Epa AP
3. Kulkarni AA
4. Kottmann RM
5. McCarthy CE
6. Johnson GV
7. Thatcher TH
8. Phipps RP
9. Sime PJ
Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules.; American journal of respiratory cell and molecular biology; Vol 50(4). 2014 Apr.
1. Rosas IO
2. Kottmann RM
3. Kottman RM
4. Sime PJ
New light is shed on the enigmatic origin of the lung myofibroblast.; American journal of respiratory and critical care medicine; Vol 188(7). 2013 Oct 1.
1. Kulkarni AA
2. Thatcher TH
3. Hsiao HM
4. Olsen KC
5. Kottmann RM
6. Morrissette J
7. Wright TW
8. Phipps RP
9. Sime PJ
The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis.; PloS one; Vol 8(5). 2013.
1. Kottmann RM
2. Kulkarni AA
3. Smolnycki KA
4. Lyda E
5. Dahanayake T
6. Salibi R
7. Honnons S
8. Jones C
9. Isern NG
10. Hu JZ
11. Nathan SD
12. Grant G
13. Phipps RP
14. Sime PJ
Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β.; American journal of respiratory and critical care medicine; Vol 186(8). 2012 Oct 15.
1. Davies ER
2. Haitchi HM
3. Thatcher TH
4. Sime PJ
5. Kottmann RM
6. Ganesan A
7. Packham G
8. O'Reilly KM
9. Davies DE
Spiruchostatin A inhibits proliferation and differentiation of fibroblasts from patients with pulmonary fibrosis.; American journal of respiratory cell and molecular biology; Vol 46(5). 2012 May.
1. Olsen KC
2. Sapinoro RE
3. Kottmann RM
4. Kulkarni AA
5. Iismaa SE
6. Johnson GV
7. Thatcher TH
8. Phipps RP
9. Sime PJ
Transglutaminase 2 and its role in pulmonary fibrosis.; American journal of respiratory and critical care medicine; Vol 184(6). 2011 Sep 15.
1. Kottmann RM
2. Kelly J
3. Lyda E
4. Gurell M
5. Stalica J
6. Ormsby W
7. Moon K
8. Trawick D
9. Sime PJ
Bronchoscopy with bronchoalveolar lavage: determinants of yield and impact on management in immunosuppressed patients.; Thorax; Vol 66(9). 2011 Sep.
1. Manganaris C
2. Wittlin S
3. Xu H
4. Gurell M
5. Sime P
6. Kottmann RM
Metastatic papillary thyroid carcinoma and severe airflow obstruction.; Chest; Vol 138(3). 2010 Sep.
1. Ferguson HE
2. Thatcher TH
3. Olsen KC
4. Garcia-Bates TM
5. Baglole CJ
6. Kottmann RM
7. Strong ER
8. Phipps RP
9. Sime PJ
Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism.; American journal of physiology. Lung cellular and molecular physiology; Vol 297(5). 2009 Nov.
1. Kottmann RM
2. Hogan CM
3. Phipps RP
4. Sime PJ
Determinants of initiation and progression of idiopathic pulmonary fibrosis.; Respirology (Carlton, Vic.); Vol 14(7). 2009 Sep.
1. Gurell MN
2. Kottmann RM
3. Xu H
4. Sime PJ
Exogenous lipoid pneumonia: an unexpected complication of substance abuse.; Annals of internal medicine; Vol 149(5). 2008 Sep 2.
1. Lakatos HF
2. Thatcher TH
3. Kottmann RM
4. Garcia TM
5. Phipps RP
6. Sime PJ
The Role of PPARs in Lung Fibrosis.; PPAR research; Vol 2007. 2007.