URMC / Labs / Mooney Lab / Publications Publications Favazzo LJGill ALFarnsworth CWMooney RAGill SR Response of nor and nos contributes to Staphylococcus aureus virulence and metabolism.; Journal of bacteriology. 2019 Feb 19. Moriarty TFHarris LGMooney RAWenke JCRiool MZaat SAJMoter ASchaer TPKhanna NKuehl RAlt VMontali ALiu JZeiter SBusscher HJGrainger DWRichards RG Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019 Jan 22. Farnsworth CWSchott EMBenvie AKates SLSchwarz EMGill SRZuscik MJMooney RA Exacerbated Staphylococcus aureus Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity.; Journal of immunology (Baltimore, Md. : 1950). 2018 Jun 01. Schott EMFarnsworth CWGrier ALillis JASoniwala SDadourian GHBell RDDoolittle MLVillani DAAwad HKetz JPKamal FAckert-Bicknell CAshton JMGill SRMooney RAZuscik MJ Targeting the gut microbiome to treat the osteoarthritis of obesity.; JCI insight; Vol 3(8). 2018 Apr 19. Farnsworth CWSchott EMBenvie AMZukoski JKates SLSchwarz EMGill SRZuscik MJMooney RA Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation and osteolysis during Staphylococcus aureus implant-associated bone infection.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2017 Dec 11. Farnsworth CWSchott EMJensen SEZukoski JBenvie AMRefaai MAKates SLSchwarz EMZuscik MJGill SRMooney RA Adaptive upregulation of Clumping Factor A (ClfA) by S. aureus in the obese, type 2 diabetic host mediates increased virulence.; Infection and immunity. 2017 Mar 20. Dar QASchott EMCatheline SEMaynard RDLiu ZKamal FFarnsworth CWKetz JPMooney RAHilton MJJonason JHPrawitt JZuscik MJ Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis.; PloS one; Vol 12(4). 2017. Wexler OGough MSMorgan MAMack CMApostolakos MJDoolin KPMooney RAArning EBottiglieri TPietropaoli AP Methionine Metabolites in Patients With Sepsis.; Journal of intensive care medicine. 2016 Sep 2. Hamada DMaynard RSchott EDrinkwater CJKetz JPKates SLJonason JHHilton MJZuscik MJMooney RA Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus.; Arthritis & rheumatology (Hoboken, N.J.); Vol 68(6). 2016 Jun. Beier EEInzana JASheu TJShu LPuzas JEMooney RA Effects of Combined Exposure to Lead and High-Fat Diet on Bone Quality in Juvenile Male Mice.; Environmental health perspectives; Vol 123(10). 2015 Oct. Barry CTHazard CHah ZCheng GPartin AMooney RAChuang KHCao WRubens DJParker KJ Shear wave dispersion in lean versus steatotic rat livers.; Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine; Vol 34(6). 2015 Jun. Farnsworth CWShehatou CTMaynard RNishitani KKates SLZuscik MJSchwarz EMDaiss JLMooney RA A humoral immune defect distinguishes the response to Staphylococcus aureus infections in mice with obesity and type 2 diabetes from that in mice with type 1 diabetes.; Infection and immunity; Vol 83(6). 2015 Jun. Shu LBeier ESheu TZhang HZuscik MJPuzas EJBoyce BFMooney RAXing L High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment.; Calcified tissue international; Vol 96(4). 2015 Apr. Barry CTHah ZPartin AMooney RAChuang KHAugustine AAlmudevar ACao WRubens DJParker KJ Mouse liver dispersion for the diagnosis of early-stage Fatty liver disease: a 70-sample study.; Ultrasound in medicine & biology; Vol 40(4). 2014 Apr. David MAJones KHInzana JAZuscik MJAwad HAMooney RA Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes.; PloS one; Vol 9(3). 2014. Brown MLYukata KFarnsworth CWChen DGAwad HHilton MJO'Keefe RJXing LMooney RAZuscik MJ Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.; PloS one; Vol 9(6). 2014. Inzana JAKung MShu LHamada DXing LPZuscik MJAwad HAMooney RA Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur.; Bone; Vol 57(1). 2013 Nov. Shi JXLiang QQWang YJMooney RABoyce BFXing L Use of a whole-slide imaging system to assess the presence and alteration of lymphatic vessels in joint sections of arthritic mice.; Biotechnic & histochemistry : official publication of the Biological Stain Commission; Vol 88(8). 2013 Nov. Mirando AJLiu ZMoore TLang AKohn AOsinski AMO'Keefe RJMooney RAZuscik MJHilton MJ RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.; Arthritis and rheumatism; Vol 65(10). 2013 Oct. Curtin WMMenegus MAPatru MMPeterson CJMetlay LAMooney RAStanwood NLScheible ALDorgan A Midtrimester fetal herpes simplex-2 diagnosis by serology, culture and quantitative polymerase chain reaction.; Fetal diagnosis and therapy; Vol 33(2). 2013. Barry CTMills BHah ZMooney RARyan CKRubens DJParker KJ Shear wave dispersion measures liver steatosis.; Ultrasound in medicine & biology; Vol 38(2). 2012 Feb. Clementi AHGaudy AMZimmers TAKoniaris LGMooney RA Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse.; Metabolism: clinical and experimental; Vol 60(11). 2011 Nov. Sampson ERHilton MJTian YChen DSchwarz EMMooney RABukata SVO'Keefe RJAwad HPuzas JERosier RNZuscik MJ Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.; Science translational medicine; Vol 3(101). 2011 Sep 21. Gough MSMorgan MAMack CMDarling DCFrasier LMDoolin KPApostolakos MJStewart JCGraves BTArning EBottiglieri TMooney RAFrampton MWPietropaoli AP The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis.; Critical care medicine; Vol 39(6). 2011 Jun. Mooney RASampson ERLerea JRosier RNZuscik MJ High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury.; Arthritis research & therapy; Vol 13(6). 2011. Gaudy AMClementi AHCampbell JSSmrcka AVMooney RA Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes.; The Journal of biological chemistry; Vol 285(53). 2010 Dec 31. Galloway CAAshton JSparks JDMooney RASmith HC Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.; Biochimica et biophysica acta; Vol 1802(11). 2010 Nov. Clementi AHGaudy AMvan Rooijen NPierce RHMooney RA Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.; Biochimica et biophysica acta; Vol 1792(11). 2009 Nov. Thornburg LLKnight KMPeterson CJMcCall KBMooney RAPressman EK Maternal serum alpha-fetoprotein values in type 1 and type 2 diabetic patients.; American journal of obstetrics and gynecology; Vol 199(2). 2008 Aug. Navaneethan SDMooney RASloand J Pseudo-anion gap acidosis; NDT Plus; Vol 1(2), pp. 94-96. 2008 Jan 01. Mooney RA Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis.; Journal of applied physiology (Bethesda, Md. : 1985); Vol 102(2). 2007 Feb. Chagnon MJElchebly MUetani NDombrowski LCheng AMooney RAMarette ATremblay ML Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma.; Canadian journal of physiology and pharmacology; Vol 84(7). 2006 Jul. Klover PJClementi AHMooney RA Interleukin-6 depletion selectively improves hepatic insulin action in obesity.; Endocrinology; Vol 146(8). 2005 Aug. LeVea CMReeder JEMooney RA EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation.; Experimental cell research; Vol 297(1). 2004 Jul 1. Klover PJMooney RA Hepatocytes: critical for glucose homeostasis.; The international journal of biochemistry & cell biology; Vol 36(5). 2004 May. Baliff JPMooney RA New developments in prenatal screening for Down syndrome.; American journal of clinical pathology; Vol 120 Suppl. 2003 Dec. Klover PJZimmers TAKoniaris LGMooney RA Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice.; Diabetes; Vol 52(11). 2003 Nov. Arnold GLHyman SLMooney RAKirby RS Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies.; Journal of autism and developmental disorders; Vol 33(4). 2003 Aug. Pearce DAMcCall KMooney RAChattopadhyay SCurran TM Altered amino acid levels in sera of a mouse model for juvenile neuronal ceroid lipofuscinoses.; Clinica chimica acta; international journal of clinical chemistry; Vol 332(1-2). 2003 Jun. Polliotti BMFry AGSaller DNMooney RACox CMiller RK Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia.; Obstetrics and gynecology; Vol 101(6). 2003 Jun. Senn JJKlover PJNowak IAZimmers TAKoniaris LGFurlanetto RWMooney RA Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.; The Journal of biological chemistry; Vol 278(16). 2003 Apr 18. Mooney RALeVea CM The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting.; Current topics in medicinal chemistry; Vol 3(7). 2003. Senn JJKlover PJNowak IAMooney RA Interleukin-6 induces cellular insulin resistance in hepatocytes.; Diabetes; Vol 51(12). 2002 Dec. Symons JRLeVea CMMooney RA Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes.; The Biochemical journal; Vol 365(Pt 2). 2002 Jul 15. Mooney RASenn JCameron SInamdar NBoivin LMShang YFurlanetto RW Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance.; The Journal of biological chemistry; Vol 276(28). 2001 Jul 13. Levea CMMcgary CTSymons JRMooney RA PTP LAR expression compared to prognostic indices in metastatic and non-metastatic breast cancer.; Breast cancer research and treatment; Vol 64(2). 2000 Nov. Bleyle LAPeng YEllis CMooney RA Dissociation of PTPase levels from their modulation of insulin receptor signal transduction.; Cellular signalling; Vol 11(10). 1999 Oct. Hostetler MAArnold GLMooney RBennett MJRinaldo PRoe CR Hypoketotic hypoglycemic coma in a 21-month-old child.; Annals of emergency medicine; Vol 34(3). 1999 Sep. Saller DNCanick JAKellner LHRose NCGarza JFrench CAMooney RA Maternal serum analyte levels in pregnancies with fetal Down syndrome resulting from translocations.; American journal of obstetrics and gynecology; Vol 177(4). 1997 Oct. Phung TLMooney RAKulas DTSparks CESparks JD Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells.; Biochemical and biophysical research communications; Vol 237(2). 1997 Aug 18.