Mooney Lab
Welcome to the Mooney Lab
The Mooney Laboratory studies the impact of obesity and associated type 2 diabetes on musculoskeletal diseases, including osteoarthritis, bone infection (osteomyelitis), and fracture repair. Obesity affects more than one third of the adult population in the US with another third being overweight. While it is very well appreciated that obesity is associated with metabolic syndrome and is linked to heart disease, stroke, type 2 diabetes, and cancer, it is only now being revealed that orthopedic pathologies are also impacted by the obesity epidemic.
With strong collaborations with fellow investigators in the Center for Musculoskeletal Research and in the Department of Microbiology and Immunology, the Mooney Lab is contributing to this very important area of clinical significance.
Robert A. Mooney, Ph.D.
Principal Investigator
- Response of nor and nos contributes to Staphylococcus aureus virulence and metabolism.; Journal of bacteriology. 2019 Feb 19.
- Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019 Jan 22.
- Exacerbated Staphylococcus aureus Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity.; Journal of immunology (Baltimore, Md. : 1950). 2018 Jun 01.
Contact Us
Mooney Lab
601 Elmwood Ave, Box 608
Rochester, NY 14642