URMC / Labs / O'Banion-Olschowka Labs / Publications

Recent Publications

1. Heneka MT
2. van der Flier WM
3. Jessen F
4. Hoozemanns J
5. Thal DR
6. Boche D
7. Brosseron F
8. Teunissen C
9. Zetterberg H
10. Jacobs AH
11. Edison P
12. Ramirez A
13. Cruchaga C
14. Lambert JC
15. Laza AR
16. Sanchez-Mut JV
17. Fischer A
18. Castro-Gomez S
19. Stein TD
20. Kleineidam L
21. Wagner M
22. Neher JJ
23. Cunningham C
24. Singhrao SK
25. Prinz M
26. Glass CK
27. Schlachetzki JCM
28. Butovsky O
29. Kleemann K
30. De Jaeger PL
31. Scheiblich H
32. Brown GC
33. Landreth G
34. Moutinho M
35. Grutzendler J
36. Gomez-Nicola D
37. McManus RM
38. Andreasson K
39. Ising C
40. Karabag D
41. Baker DJ
42. Liddelow SA
43. Verkhratsky A
44. Tansey M
45. Monsonego A
46. Aigner L
47. Dorothée G
48. Nave KA
49. Simons M
50. Constantin G
51. Rosenzweig N
52. Pascual A
53. Petzold GC
54. Kipnis J
55. Venegas C
56. Colonna M
57. Walter J
58. Tenner AJ
59. O'Banion MK
60. Steinert JR
61. Feinstein DL
62. Sastre M
63. Bhaskar K
64. Hong S
65. Schafer DP
66. Golde T
67. Ransohoff RM
68. Morgan D
69. Breitner J
70. Mancuso R
71. Riechers SP
Neuroinflammation in Alzheimer disease.; Nature reviews. Immunology. 2024 Dec 09.
1. Strohm AO
2. Oldfield S
3. Hernady E
4. Johnston CJ
5. Marples B
6. O'Banion MK
7. Majewska AK
Biological sex, microglial signaling pathways, and radiation exposure shape cortical proteomic profiles and behavior in mice.; Brain, behavior, & immunity - health; Vol 43, pp. 100911. 2024 Nov 25.
1. Peng W
2. Chung KB
3. Lawrence BP
4. O'Banion MK
5. Dirksen RT
6. Wojtovich AP
7. Onukwufor JO
DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid β proteotoxicity.; Free radical biology & medicine. 2024 Sep 22.
1. Peng W
2. Chung KB
3. Lawrence BP
4. O'Banion MK
5. Dirksen RT
6. Wojtovich AP
7. Onukwufor JO
DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid β proteotoxicity.; bioRxiv : the preprint server for biology. 2024 Aug 09.
1. Strohm AO
2. Johnston C
3. Hernady E
4. Marples B
5. O'Banion MK
6. Majewska AK
Cranial irradiation disrupts homeostatic microglial dynamic behavior.; Journal of neuroinflammation; Vol 21(1), pp. 82. 2024 Apr 03.
1. Majewska A
2. Le L
3. Feidler A
4. Li H
5. Kara-Pabani K
6. Lamantia C
7. O'Banion MK
Noradrenergic signaling controls Alzheimer's disease pathology via activation of microglial β2 adrenergic receptors.; Research square. 2024 Feb 26.
1. Thariat J
2. Little MP
3. Zablotska LB
4. Samson P
5. O'Banion MK
6. Leuraud K
7. Bergom C
8. Girault G
9. Azimzadeh O
10. Bouffler S
11. Hamada N
Radiotherapy for non-cancer diseases: benefits and long-term risks.; International journal of radiation biology. 2024 Jan 05.
1. Karaahmet B
2. Olschowka JA
3. O'Banion MK
Inconsistent Effects of Glatiramer Acetate Treatment in the 5xFAD Mouse Model of Alzheimer's Disease.; Pharmaceutics; Vol 15(7). 2023 Jun 24.
1. Hinshaw RG
2. Schroeder MK
3. Ciola J
4. Varma C
5. Colletti B
6. Liu B
7. Liu GG
8. Shi Q
9. Williams JP
10. O'Banion MK
11. Caldarone BJ
12. Lemere CA
High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations.; International journal of molecular sciences; Vol 24(4). 2023 Feb 10.
1. Hinkle JJ
2. Olschowka JA
3. Williams JP
4. O'Banion MK
Pharmacologic manipulation of complement receptor 3 prevents dendritic spine loss and cognitive impairment after acute cranial radiation.; International journal of radiation oncology, biology, physics. 2023 Jan 22.
1. Owlett LD
2. Karaahmet B
3. Le L
4. Belcher EK
5. Dionisio-Santos D
6. Olschowka JA
7. Elliott MR
8. O'Banion MK
Correction: Gas6 induces infammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer's disease.; Journal of neuroinflammation; Vol 20(1), pp. 254. 2023 Jan 06.
1. Le L
2. Feidler AM
3. Li H
4. Kara-Pabani K
5. Lamantia C
6. O'Banion MK
7. Majewska KA
Noradrenergic signaling controls Alzheimer's disease pathology via activation of microglial β2 adrenergic receptors.; bioRxiv : the preprint server for biology. 2023 Jan 04.
1. Brouxhon SM
2. O'Banion MK
3. Kyrkanides S
AAV gene therapy vectors in the TMJ.; Clinical and experimental dental research. 2022 Jul 24.
1. Karaahmet B
2. Le L
3. Mendes MS
4. Majewska AK
5. O'Banion MK
Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology.; Journal of neuroinflammation; Vol 19(1). 2022 Jul 04.
1. Brouxhon SM
2. O'Banion MK
3. Dickerson IM
4. Kyrkanides S
Calcitonin gene-related peptide: An intra-articular therapeutic target for TMJ disorders.; Clinical and experimental dental research. 2022 Jun 14.
1. Owlett LD
2. Karaahmet B
3. Le L
4. Belcher EK
5. Dionisio-Santos D
6. Olschowka JA
7. Elliott MR
8. O'Banion MK
Gas6 induces inflammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer's disease.; Journal of neuroinflammation; Vol 19(1). 2022 Feb 07.
1. Porsteinsson AP
2. Rangaraju S
3. Spires-Jones TL
4. O'Banion MK
Alzheimer's Disease and Related Dementias: From Risk Factors to Disease Pathogenesis.; The European journal of neuroscience. 2022 Jan 02.
1. Zablotska LB
2. Zupunski L
3. Leuraud K
4. Lopes J
5. Hinkle J
6. Pugeda T
7. Delgado T
8. Olschowka J
9. Williams J
10. O'Banion MK
11. Boice JD
12. Cohen SS
13. Mumma MT
14. Dauer LT
15. Britten RA
16. Stephenson S
Radiation and CNS effects: Summary of evidence from a recent symposium of the Radiation Research Society.; International journal of radiation biology. 2022 Jan 01.
1. Schroeder MK
2. Liu B
3. Hinshaw RG
4. Park MA
5. Wang S
6. Dubey S
7. Liu GG
8. Shi Q
9. Holton P
10. Reiser V
11. Jones PA
12. Trigg W
13. Di Carli MF
14. Caldarone BJ
15. Williams JP
16. O'Banion MK
17. Lemere CA
Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice.; International journal of molecular sciences; Vol 22(24). 2021 Dec 10.
1. Whitelaw BS
2. Tanny S
3. Johnston CJ
4. Majewska AK
5. O'Banion MK
6. Marples B
In vivo imaging of the microglial landscape after whole brain radiation therapy.; International journal of radiation oncology, biology, physics. 2021 Jul 24.
1. Herr D
2. Jew K
3. Wong C
4. Kennell A
5. Gelein R
6. Chalupa D
7. Raab A
8. Oberdörster G
9. Olschowka J
10. O'Banion MK
11. Elder A
Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer's disease in the 3xTgAD mouse model.; Neurotoxicology. 2021 Mar 29.
1. Dionisio-Santos DA
2. Karaahmet B
3. Belcher EK
4. Owlett LD
5. Trojanczyk LA
6. Olschowka JA
7. O'Banion MK
Evaluating Effects of Glatiramer Acetate Treatment on Amyloid Deposition and Tau Phosphorylation in the 3xTg Mouse Model of Alzheimer's Disease.; Frontiers in neuroscience; Vol 15. 2021.
1. Owlett L
2. Belcher EK
3. Dionisio-Santos DA
4. Williams JP
5. Olschowka JA
6. O'Banion MK
Space radiation does not alter amyloid or tau pathology in the 3xTg mouse model of Alzheimer's disease.; Life sciences in space research; Vol 27. 2020 Nov.
1. Chen Q
2. Baran TM
3. Rooks B
4. O'Banion MK
5. Mapstone M
6. Zhang Z
7. Lin F
Cognitively supernormal older adults maintain a unique structural connectome that is resistant to Alzheimer's pathology.; NeuroImage. Clinical; Vol 28. 2020 Sep 08.
1. Dylla L
2. Cushman JT
3. Abar B
4. Benesch C
5. Jones CMC
6. O'Banion MK
7. Adler DH
Retrospective analysis of the hemodynamic consequences of prehospital supplemental oxygen in acute stroke.; The American journal of emergency medicine. 2020 Jul 11.
1. Belcher EK
2. Sweet TB
3. Karaahmet B
4. Dionisio-Santos DA
5. Owlett LD
6. Leffler KA
7. Janelsins MC
8. Williams JP
9. Olschowka JA
10. O'Banion MK
Cranial irradiation acutely and persistently impairs injury-induced microglial proliferation.; Brain, behavior, & immunity - health; Vol 4. 2020 Apr.
1. Chockanathan U
2. Warner EJ
3. Turpin L
4. O'Banion MK
5. Padmanabhan K
Altered dorsal CA1 neuronal population coding in the APP/PS1 mouse model of Alzheimer's disease.; Scientific reports; Vol 10(1). 2020 Jan 23.
1. Dionisio-Santos DA
2. Behrouzi A
3. Olschowka JA
4. O'Banion MK
Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer's Disease.; Frontiers in neuroscience; Vol 14. 2020.
1. Hinkle JJ
2. Olschowka JA
3. Love TM
4. Williams JP
5. O'Banion MK
Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice.; Scientific reports; Vol 9(1). 2019 Dec 11.
1. Rivera-Escalera F
2. Pinney JJ
3. Owlett L
4. Ahmed H
5. Thakar J
6. Olschowka JA
7. Elliott MR
8. O'Banion MK
IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia.; Journal of neuroinflammation; Vol 16(1). 2019 Dec 10.
1. Jew K
2. Herr D
3. Wong C
4. Kennell A
5. Morris-Schaffer K
6. Oberdörster G
7. O'Banion MK
8. Cory-Slechta DA
9. Elder A
Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.; Particle and fibre toxicology; Vol 16(1). 2019 Nov 26.
1. Liu B
2. Hinshaw RG
3. Le KX
4. Park MA
5. Wang S
6. Belanger AP
7. Dubey S
8. Frost JL
9. Shi Q
10. Holton P
11. Trojanczyk L
12. Reiser V
13. Jones PA
14. Trigg W
15. Di Carli MF
16. Lorello P
17. Caldarone BJ
18. Williams JP
19. O'Banion MK
20. Lemere CA
Space-like 56Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer's-like transgenic mice.; Scientific reports; Vol 9(1). 2019 Aug 20.
1. Dionisio-Santos DA
2. Olschowka JA
3. O'Banion MK
Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer's disease.; Journal of neuroinflammation; Vol 16(1). 2019 Apr 05.
1. Begolly S
2. Olschowka JA
3. Love T
4. Williams JP
5. O'Banion MK
Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion.; Glia. 2017 Dec 30.
1. Fleming EH
2. Ochoa EE
3. Nichols JE
4. O'Banion MK
5. Salkind AR
6. Roberts NJ
Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus.; Journal of medical virology. 2017 Aug 30.
1. Sweet TB
2. Hurley SD
3. Wu MD
4. Olschowka JA
5. Williams JP
6. O'Banion MK
Neurogenic Effects of Low-Dose Whole-Body HZE (Fe) Ion and Gamma Irradiation.; Radiation research. 2016 Dec 1.
1. Williams JP
2. Calvi L
3. Chakkalakal JV
4. Finkelstein JN
5. O'Banion MK
6. Puzas E
Addressing the Symptoms or Fixing the Problem? Developing Countermeasures against Normal Tissue Radiation Injury.; Radiation research. 2016 Jun 22.
1. Heneka M
2. Andreasson KI
3. Bachstetter AD
4. Colonna M
5. Ginhoux F
6. Holmes C
7. Lamb B
8. Landreth G
9. Lee DC
10. Low D
11. Lynch MA
12. Monsonego A
13. O'Banion MK
14. Pekny M
15. Puschmann T
16. Russek-Blum N
17. Sandusky LA
18. Selenica MB
19. Takata K
20. Teeling J
21. Town T
22. Van Eldik LJ
23. Schulz JB
Targeting innate immunity for neurodegenerative disorders of the central nervous system.; Journal of neurochemistry. 2016 Jun 1.
1. Begolly S
2. Shrager PG
3. Olschowka JA
4. Williams JP
5. O'Banion MK
Fractionation Spares Mice From Radiation-Induced Reductions in Weight Gain But Does Not Prevent Late Oligodendrocyte Lineage Side Effects.; International journal of radiation oncology, biology, physics. 2016 May 12.
1. McConnell SE
2. O'Banion MK
3. Cory-Slechta DA
4. Olschowka JA
5. Opanashuk LA
Characterization of binge-dosed methamphetamine-induced neurotoxicity and neuroinflammation.; Neurotoxicology. 2015 Aug 14.
1. Dever DP
2. Adham ZO
3. Thompson B
4. Genestine M
5. Cherry J
6. Olschowka JA
7. DiCicco-Bloom E
8. Opanashuk LA
Aryl Hydrocarbon Receptor (AhR) Deletion in Cerebellar Granule Neuron Precursors Impairs Neurogenesis.; Developmental neurobiology. 2015 Aug 3.
1. Moravan MJ
2. Olschowka JA
3. Williams JP
4. O'Banion MK
Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling.; Journal of neuroinflammation; Vol 13(1). 2016.
1. Cherry JD
2. Olschowka JA
3. O'Banion MK
Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation.; Journal of neuroinflammation; Vol 12(1). 2015.
1. Brouxhon SM
2. Kyrkanides S
3. Teng X
4. O'Banion MK
5. Clarke R
6. Byers S
7. Ma L
Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers.; Molecular carcinogenesis; Vol 53(11). 2014 Nov.
1. O'Banion MK
Does peripheral inflammation contribute to Alzheimer disease? Evidence from animal models.; Neurology; Vol 83(6). 2014 Aug 5.
1. Sweet TB
2. Panda N
3. Hein AM
4. Das SL
5. Hurley SD
6. Olschowka JA
7. Williams JP
8. O'Banion MK
Central Nervous System Effects of Whole-Body Proton Irradiation.; Radiation research. 2014 Jun 17.
1. Cherry JD
2. Olschowka JA
3. O Banion MK
Neuroinflammation and M2 microglia: the good, the bad, and the inflamed.; Journal of neuroinflammation; Vol 11(1). 2014 Jun 3.
1. Rivera-Escalera F
2. Matousek SB
3. Ghosh S
4. Olschowka JA
5. O'Banion MK
Interleukin-1β mediated amyloid plaque clearance is independent of CCR2 signaling in the APP/PS1 mouse model of Alzheimer's disease.; Neurobiology of disease; Vol 69C. 2014 May 27.
1. Brouxhon SM
2. Kyrkanides S
3. Teng X
4. Athar M
5. Ghazizadeh S
6. Simon M
7. O'Banion MK
8. Ma L
Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.; Oncogene; Vol 33(2). 2014 Jan 9.
1. Cherry JD
2. Olschowka JA
3. O'Banion MK
Are "Resting" Microglia More "M2"?; Frontiers in immunology; Vol 5. 2014.