URMC / Labs / Perkins / Zhang Lab / Publications

Publications

1. Ping Koh C
2. Govind Bahirvani A
3. Qiuxia Wang C
4. Yokomizo T
5. Ee Lin Ng C
6. Du L
7. Tergaonkar V
8. Chih-Cheng Voon D
9. Kitamura H
10. Hosoi H
11. Sonoki T
12. Meng Huang Michelle M
13. Jye Tan L
14. Niibori-Nambu A
15. Zhang Y
16. Perkins AS
17. Hossain Z
18. Tenen DG
19. Ito Y
20. Venkatesh B
21. Osato M
Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells.; Gene. 2022 Jan 13.
1. Zhang Y
2. McGrath KE
3. Ayoub E
4. Kingsley PD
5. Yu H
6. Fegan K
7. McGlynn KA
8. Rudzinskas S
9. Palis J
10. Perkins AS
Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells.; Cell reports; Vol 36(7). 2021 Aug 17.
1. McGlynn KA
2. Sun R
3. Vonica A
4. Rudzinskas S
5. Zhang Y
6. Perkins AS
Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.; Experimental hematology; Vol 85, pp. 20-32.e3. 2020 May 11.
1. Christodoulou C
2. Spencer JA
3. Yeh SA
4. Turcotte R
5. Kokkaliaris KD
6. Panero R
7. Ramos A
8. Guo G
9. Seyedhassantehrani N
10. Esipova TV
11. Vinogradov SA
12. Rudzinskas S
13. Zhang Y
14. Perkins AS
15. Orkin SH
16. Calogero RA
17. Schroeder T
18. Lin CP
19. Camargo FD
Live-animal imaging of native haematopoietic stem and progenitor cells.; Nature; Vol 578(7794). 2020 Feb.
1. Frisch BJ
2. Hoffman CM
3. Latchney SE
4. LaMere MW
5. Myers J
6. Ashton J
7. Li AJ
8. Saunders J
9. Palis J
10. Perkins AS
11. McCabe A
12. Smith JN
13. McGrath KE
14. Rivera-Escalera F
15. McDavid A
16. Liesveld JL
17. Korshunov VA
18. Elliott MR
19. MacNamara KC
20. Becker MW
21. Calvi LM
Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.; JCI insight; Vol 5. 2019 Apr 18.
1. Ayoub E
2. Wilson MP
3. McGrath KE
4. Li AJ
5. Frisch BJ
6. Palis J
7. Calvi LM
8. Zhang Y
9. Perkins AS
EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription.; Nature communications; Vol 9(1). 2018 Oct 12.
1. Mateo F
2. Arenas EJ
3. Aguilar H
4. Serra-Musach J
5. de Garibay GR
6. Boni J
7. Maicas M
8. Du S
9. Iorio F
10. Herranz-Ors C
11. Islam A
12. Prado X
13. Llorente A
14. Petit A
15. Vidal A
16. Català I
17. Soler T
18. Venturas G
19. Rojo-Sebastian A
20. Serra H
21. Cuadras D
22. Blanco I
23. Lozano J
24. Canals F
25. Sieuwerts AM
26. de Weerd V
27. Look MP
28. Puertas S
29. García N
30. Perkins AS
31. Bonifaci N
32. Skowron M
33. Gómez-Baldó L
34. Hernández V
35. Martínez-Aranda A
36. Martínez-Iniesta M
37. Serrat X
38. Cerón J
39. Brunet J
40. Barretina MP
41. Gil M
42. Falo C
43. Fernández A
44. Morilla I
45. Pernas S
46. Plà MJ
47. Andreu X
48. Seguí MA
49. Ballester R
50. Castellà E
51. Nellist M
52. Morales S
53. Valls J
54. Velasco A
55. Matias-Guiu X
56. Figueras A
57. Sánchez-Mut JV
58. Sánchez-Céspedes M
59. Cordero A
60. Gómez-Miragaya J
61. Palomero L
62. Gómez A
63. Gajewski TF
64. Cohen EEW
65. Jesiotr M
66. Bodnar L
67. Quintela-Fandino M
68. López-Bigas N
69. Valdés-Mas R
70. Puente XS
71. Viñals F
72. Casanovas O
73. Graupera M
74. Hernández-Losa J
75. Ramón Y Cajal S
76. García-Alonso L
77. Saez-Rodriguez J
78. Esteller M
79. Sierra A
80. Martín-Martín N
81. Matheu A
82. Carracedo A
83. González-Suárez E
84. Nanjundan M
85. Cortés J
86. Lázaro C
87. Odero MD
88. Martens JWM
89. Moreno-Bueno G
90. Barcellos-Hoff MH
91. Villanueva A
92. Gomis RR
93. Pujana MA
Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.; Oncogene; Vol 36(19). 2017 May 11.
1. Fenouille N
2. Bassil CF
3. Ben-Sahra I
4. Benajiba L
5. Alexe G
6. Ramos A
7. Pikman Y
8. Conway AS
9. Burgess MR
10. Li Q
11. Luciano F
12. Auberger P
13. Galinsky I
14. DeAngelo DJ
15. Stone RM
16. Zhang Y
17. Perkins AS
18. Shannon K
19. Hemann MT
20. Puissant A
21. Stegmaier K
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.; Nature medicine; Vol 23(3). 2017 Mar.
1. Crane GM
2. Perkins AS
Leukemic presentation of diffuse large B-cell lymphoma: an unusual pattern associated with splenic involvement.; Blood; Vol 130(20). 2017 Jan 16.
1. Wilson M
2. Tsakraklides V
3. Tran M
4. Xiao YY
5. Zhang Y
6. Perkins AS
EVI1 Interferes with Myeloid Maturation via Transcriptional Repression of Cebpa, via Binding to Two Far Downstream Regulatory Elements.; The Journal of biological chemistry; Vol 291(26). 2016 Jun 24.
1. Glass C
2. Wilson M
3. Gonzalez R
4. Zhang Y
5. Perkins AS
The role of EVI1 in myeloid malignancies.; Blood cells, molecules & diseases; Vol 53(1-2). 2014 Jun.
1. Juneja SC
2. Vonica A
3. Zeiss C
4. Lezon-Geyda K
5. Yatsula B
6. Sell DR
7. Monnier VM
8. Lin S
9. Ardito T
10. Eyre D
11. Reynolds D
12. Yao Z
13. Awad HA
14. Yu H
15. Wilson M
16. Honnons S
17. Boyce BF
18. Xing L
19. Zhang Y
20. Perkins AS
Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.; Bone; Vol 60. 2014 Mar.
1. Bard-Chapeau EA
2. Szumska D
3. Jacob B
4. Chua BQ
5. Chatterjee GC
6. Zhang Y
7. Ward JM
8. Urun F
9. Kinameri E
10. Vincent SD
11. Ahmed S
12. Bhattacharya S
13. Osato M
14. Perkins AS
15. Moore AW
16. Jenkins NA
17. Copeland NG
Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.; PloS one; Vol 9(2). 2014.
1. Zhang Y
2. Owens K
3. Hatem L
4. Glass CH
5. Karuppaiah K
6. Camargo F
7. Perkins AS
Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.; Blood; Vol 122(16). 2013 Oct 17.
1. Deng X
2. Cao Y
3. Liu Y
4. Li F
5. Sambandam K
6. Rajaraman S
7. Perkins AS
8. Fields AP
9. Hellmich MR
10. Townsend CM
11. Thompson EA
12. Ko TC
Overexpression of Evi-1 oncoprotein represses TGF-β signaling in colorectal cancer.; Molecular carcinogenesis; Vol 52(4). 2013 Apr.
1. Arshad M
2. Ye Z
3. Gu X
4. Wong CK
5. Liu Y
6. Li D
7. Zhou L
8. Zhang Y
9. Bay WP
10. Yu VC
11. Li P
RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.; The Journal of biological chemistry; Vol 288(12). 2013 Mar 22.
1. Glass C
2. Wuertzer C
3. Cui X
4. Bi Y
5. Davuluri R
6. Xiao YY
7. Wilson M
8. Owens K
9. Zhang Y
10. Perkins A
Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.; PloS one; Vol 8(6). 2013.
1. Bresnick EH
2. Katsumura KR
3. Lee HY
4. Johnson KD
5. Perkins AS
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies.; Nucleic acids research; Vol 40(13). 2012 Jul.
1. Zhang Y
2. Sicot G
3. Cui X
4. Vogel M
5. Wuertzer CA
6. Lezon-Geyda K
7. Wheeler J
8. Harki DA
9. Muzikar KA
10. Stolper DA
11. Dervan PB
12. Perkins AS
Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.; Biochemistry; Vol 50(48). 2011 Dec 06.
1. Zhang Y
2. Stehling-Sun S
3. Lezon-Geyda K
4. Juneja SC
5. Coillard L
6. Chatterjee G
7. Wuertzer CA
8. Camargo F
9. Perkins AS
PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.; Blood; Vol 118(14). 2011 Oct 06.
1. Qiu Y
2. Lynch J
3. Guo L
4. Yatsula B
5. Perkins AS
6. Michalak M
Regulation of the calreticulin gene by GATA6 and Evi-1 transcription factors.; Biochemistry; Vol 47(12). 2008 Mar 25.
1. Cirone P
2. Lin S
3. Griesbach HL
4. Zhang Y
5. Slusarski DC
6. Crews CM
A role for planar cell polarity signaling in angiogenesis.; Angiogenesis; Vol 11(4). 2008.
1. Perkins AS
2. Friedberg JW
Burkitt lymphoma in adults.; Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2008.
1. Jackson-Fisher AJ
2. Bellinger G
3. Shum E
4. Duong JK
5. Perkins AS
6. Gassmann M
7. Muller W
8. Kent Lloyd KC
9. Stern DF
Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4.; Oncogene; Vol 25(41). 2006 Sep 14.
1. Zhang Y
2. Yeh JR
3. Mara A
4. Ju R
5. Hines JF
6. Cirone P
7. Griesbach HL
8. Schneider I
9. Slusarski DC
10. Holley SA
11. Crews CM
A chemical and genetic approach to the mode of action of fumagillin.; Chemistry & biology; Vol 13(9). 2006 Sep.
1. Yeh JJ
2. Ju R
3. Brdlik CM
4. Zhang W
5. Zhang Y
6. Matyskiela ME
7. Shotwell JD
8. Crews CM
Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest.; Proceedings of the National Academy of Sciences of the United States of America; Vol 103(27). 2006 Jul 05.
1. Boyd KE
2. Xiao YY
3. Fan K
4. Poholek A
5. Copeland NG
6. Jenkins NA
7. Perkins AS
Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR.; Blood; Vol 107(2). 2006 Jan 15.
1. Yatsula B
2. Galvao C
3. McCrann M
4. Perkins AS
Assessment of F-MuLV-induced tumorigenesis reveals new candidate tumor genes including Pecam1, St7, and Prim2.; Leukemia; Vol 20(1). 2006 Jan.
1. Yatsula B
2. Lin S
3. Read AJ
4. Poholek A
5. Yates K
6. Yue D
7. Hui P
8. Perkins AS
Identification of binding sites of EVI1 in mammalian cells.; The Journal of biological chemistry; Vol 280(35). 2005 Sep 2.
1. Cheung PY
2. Zhang Y
3. Long J
4. Lin S
5. Zhang M
6. Jiang Y
7. Wu Z
p150(Glued), Dynein, and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs.; The Journal of biological chemistry; Vol 279(44). 2004 Oct 29.
1. Kluger HM
2. Kluger Y
3. Gilmore-Hebert M
4. DiVito K
5. Chang JT
6. Rodov S
7. Mironenko O
8. Kacinski BM
9. Perkins AS
10. Sapi E
cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model.; Laboratory investigation; a journal of technical methods and pathology; Vol 84(3). 2004 Mar.
1. Amin DN
2. Perkins AS
3. Stern DF
Gene expression profiling of ErbB receptor and ligand-dependent transcription.; Oncogene; Vol 23(7). 2004 Feb 19.
1. Chatterjee G
2. Rosner A
3. Han Y
4. Zelazny ET
5. Li B
6. Cardiff RD
7. Perkins AS
Acceleration of mouse mammary tumor virus-induced murine mammary tumorigenesis by a p53 172H transgene: influence of FVB background on tumor latency and identification of novel sites of proviral insertion.; The American journal of pathology; Vol 161(6). 2002 Dec.
1. Rui HL
2. Fan E
3. Zhou HM
4. Xu Z
5. Zhang Y
6. Lin SC
SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling.; The Journal of biological chemistry; Vol 277(45). 2002 Nov 08.
1. Kone J
2. Arroyo J
3. Savinelli T
4. Lin S
5. Boyd K
6. Wu Y
7. Nimmakayalu M
8. Copeland NG
9. Jenkins NA
10. Qumsiyeh M
11. Hu P
12. Prescott A
13. Wu H
14. Yang L
15. Roe B
16. Perkins AS
F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4.; Leukemia; Vol 16(9). 2002 Sep.
1. Ma X
2. Husain T
3. Peng H
4. Lin S
5. Mironenko O
6. Maun N
7. Johnson S
8. Tuck D
9. Berliner N
10. Krause DS
11. Perkins AS
Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library.; Blood; Vol 100(3). 2002 Aug 1.
1. Hui P
2. Glusac EJ
3. Sinard JH
4. Perkins AS
Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma).; Journal of cutaneous pathology; Vol 29(7). 2002 Aug.
1. Perkins AS
Functional genomics in the mouse.; Functional & integrative genomics; Vol 2(3). 2002 Aug.
1. Kogan SC
2. Ward JM
3. Anver MR
4. Berman JJ
5. Brayton C
6. Cardiff RD
7. Carter JS
8. de Coronado S
9. Downing JR
10. Fredrickson TN
11. Haines DC
12. Harris AW
13. Harris NL
14. Hiai H
15. Jaffe ES
16. MacLennan IC
17. Pandolfi PP
18. Pattengale PK
19. Perkins AS
20. Simpson RM
21. Tuttle MS
22. Wong JF
23. Morse HC
Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice.; Blood; Vol 100(1). 2002 Jul 1.
1. Wysolmerski JJ
2. Dann PR
3. Zelazny E
4. Dunbar ME
5. Insogna KL
6. Guise TA
7. Perkins AS
Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 17(7). 2002 Jul.
1. Zhang Y
2. Qiu WJ
3. Chan SC
4. Han J
5. He X
6. Lin SC
Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways.; The Journal of biological chemistry; Vol 277(20). 2002 May 17.
1. Zhang Y
2. Qiu WJ
3. Liu DX
4. Neo SY
5. He X
6. Lin SC
Differential molecular assemblies underlie the dual function of Axin in modulating the WNT and JNK pathways.; The Journal of biological chemistry; Vol 276(34). 2001 Aug 24.
1. Zelazny E
2. Li B
3. Anagnostopoulos AM
4. Coleman A
5. Perkins AS
Cooperating oncogenic events in murine mammary tumorigenesis: assessment of ErbB2, mutant p53, and mouse mammary tumor virus.; Experimental and molecular pathology; Vol 70(3). 2001 Jun.
1. Fong CW
2. Zhang Y
3. Neo SY
4. Lin SC
Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner.; The Biochemical journal; Vol 352 Pt 3. 2000 Dec 15.
1. Zhang Y
2. Neo SY
3. Han J
4. Lin SC
Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase.; The Journal of biological chemistry; Vol 275(32). 2000 Aug 11.
1. Hui P
2. Parkash V
3. Perkins AS
4. Carcangiu ML
Pathogenesis of placental site trophoblastic tumor may require the presence of a paternally derived X chromosome.; Laboratory investigation; a journal of technical methods and pathology; Vol 80(6). 2000 Jun.
1. Neo SY
2. Zhang Y
3. Yaw LP
4. Li P
5. Lin SC
Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate beta-catenin levels.; Biochemical and biophysical research communications; Vol 272(1). 2000 May 27.
1. Zhang Y
2. Neo SY
3. Wang X
4. Han J
5. Lin SC
Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling.; The Journal of biological chemistry; Vol 274(49). 1999 Dec 03.
1. Zhang Y
2. Neo SY
3. Han J
4. Yaw LP
5. Lin SC
RGS16 attenuates galphaq-dependent p38 mitogen-activated protein kinase activation by platelet-activating factor.; The Journal of biological chemistry; Vol 274(5). 1999 Jan 29.
1. Kim JH
2. Hui P
3. Yue D
4. Aycock J
5. Leclerc C
6. Bjoring AR
7. Perkins AS
Identification of candidate target genes for EVI-1, a zinc finger oncoprotein, using a novel selection strategy.; Oncogene; Vol 17(12). 1998 Sep 24.