Ritchlin Lab
Pathologic Bone Resorption and New Bone Formation in Inflammatory Arthritis
Bone remodeling is a dynamic and complex process finely orchestrated by cell interactions among bone-degrading osteoclasts, bone-synthesizing osteoblastosteoblasts, T cells, B cells, and natural killer cells. An imbalance between osteoclast and osteoblast activity results in skeletal and joint diseases including osteoporosis, arthritis, and non-union bone repair. These diseases impact the quality of life of patients.

Christopher T. Ritchlin, M.D., M.P.H.
Principal Investigator
Publications
- Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials.; Rheumatology and therapy. 2024 Dec 05.
- Are There Disease Endotypes in Axial Spondyloarthritis and How Would We Define Them?; The Journal of rheumatology. 2024 Oct 24.
- Safety and Efficacy of Bimekizumab in Patients with Psoriatic Arthritis: 2-Year Results from Two Phase 3 Studies.; Rheumatology and therapy. 2024 Aug 31.
- Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue.; Nature communications; Vol 15(1), pp. 7503. 2024 Aug 29.
Affiliations
News
January 15, 2025
ROChester Stimulating Access to Research during Residency (ROC StARR) Health and Immune Function Across the Lifespan to Begin July 1st
January 6, 2025
Jennifer Anolik Named Chief of Allergy, Immunology and Rheumatology Division
December 13, 2024
Ilana Abeles Receives Clinical Trial Investigator Award
December 11, 2024
AIR Faculty Shine at ACR Meeting
October 4, 2024
Dr. Jennifer Anolik Delivers Keynote Address
Contact Us
Ritchlin Lab
601 Elmwood Ave/Box 695
Rochester, NY 14642
(585) 442-3214