Ritchlin Lab
Pathologic Bone Resorption and New Bone Formation in Inflammatory Arthritis
Bone remodeling is a dynamic and complex process finely orchestrated by cell interactions among bone-degrading osteoclasts, bone-synthesizing osteoblastosteoblasts, T cells, B cells, and natural killer cells. An imbalance between osteoclast and osteoblast activity results in skeletal and joint diseases including osteoporosis, arthritis, and non-union bone repair. These diseases impact the quality of life of patients.
Christopher T. Ritchlin, M.D., M.P.H.
Principal Investigator
Publications
View All Publications- Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials.; Rheumatology and therapy. 2024 Dec 05.
- Are There Disease Endotypes in Axial Spondyloarthritis and How Would We Define Them?; The Journal of rheumatology. 2024 Oct 24.
- Safety and Efficacy of Bimekizumab in Patients with Psoriatic Arthritis: 2-Year Results from Two Phase 3 Studies.; Rheumatology and therapy. 2024 Aug 31.
- Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue.; Nature communications; Vol 15(1), pp. 7503. 2024 Aug 29.
Affiliations
News
December 11, 2024
AIR Faculty Shine at ACR Meeting
October 4, 2024
Dr. Jennifer Anolik Delivers Keynote Address
August 5, 2024
Katherine Escalera-Rivera Receives Awards
June 13, 2024
Drs. Korman and Garcia-Henandez Receive University Research Award
December 30, 2023
Jennifer Anolik Awarded RO1 to Study Role of T-bet B Cells in Rheumatoid Arthritis
Contact Us
Ritchlin Lab
601 Elmwood Ave/Box 695
Rochester, NY 14642
(585) 442-3214