Recent Publications

• 1. McKee C
  2. Foley K
  3. Andersh KM
  4. Marola OJ
  5. Wadzinski B
  6. Libby RT
  7. Shrager P
  8. Xia H
  Neuronal protein phosphatase 1β regulates glutamate release, cortical myelination, node of Ranvier formation, and action potential propagation in the optic nerve.; bioRxiv : the preprint server for biology. 2024 May 10.
• 1. Schmitd LB
  2. Hafner H
  3. Ward A
  4. Adib EA
  5. Biscola NP
  6. Kohen R
  7. Patel M
  8. Williamson RE
  9. Desai E
  10. Bennett J
  11. Saxman G
  12. Athaiya M
  13. Wilborn D
  14. Shumpert J
  15. Zhao XF
  16. Kawaguchi R
  17. Geschwind DH
  18. Hoke A
  19. Shrager P
  20. Collins CA
  21. Havton LA
  22. Kalinski AL
  23. Giger RJ
  Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration.; bioRxiv : the preprint server for biology. 2024 Mar 08.
• 1. McKee C
  2. Shrager P
  3. Mazumder AG
  4. Ganguly A
  5. Mayer A
  6. Foley K
  7. Ward N
  8. Youngman M
  9. Hou H
  10. Xia H
  Nuclear Inhibitor of Protein Phosphatase 1 (NIPP1) Regulates CNS Tau Phosphorylation and Myelination During Development.; Molecular neurobiology. 2022 Jan 06.
• 1. Fernandes KA
  2. Mitchell KL
  3. Patel A
  4. Marola OJ
  5. Shrager P
  6. Zack DJ
  7. Libby RT
  8. Welsbie DS
  Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.; Experimental eye research. 2018 Mar 08.
• 1. Lin JP
  2. Mironova YA
  3. Shrager P
  4. Giger RJ
  LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.; eLife; Vol 6. 2017 Dec 18.
• 1. Syc-Mazurek SB
  2. Fernandes KA
  3. Wilson MP
  4. Shrager P
  5. Libby RT
  Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury.; Molecular neurodegeneration; Vol 12(1). 2017 Oct 02.
• 1. Shrager P
  2. Youngman M
  Preferential conduction block of myelinated axons by nitric oxide.; Journal of neuroscience research; Vol 95(7). 2017 Jul.
• 1. Mironova YA
  2. Lenk GM
  3. Lin JP
  4. Lee SJ
  5. Twiss JL
  6. Vaccari I
  7. Bolino A
  8. Havton LA
  9. Min SH
  10. Abrams CS
  11. Shrager P
  12. Meisler MH
  13. Giger RJ
  PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms.; eLife; Vol 5. 2016 Mar 23.
• 1. Jones JM
  2. Dionne L
  3. Dell'Orco J
  4. Parent R
  5. Krueger JN
  6. Cheng X
  7. Dib-Hajj SD
  8. Bunton-Stasyshyn RK
  9. Sharkey LM
  10. Dowling JJ
  11. Murphy GG
  12. Shakkottai VG
  13. Shrager P
  14. Meisler MH
  Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder.; Neurobiology of disease. 2016 Jan 22.
• 1. Carbajal KS
  2. Mironova Y
  3. Ulrich-Lewis JT
  4. Kulkarni D
  5. Grifka-Walk HM
  6. Huber AK
  7. Shrager P
  8. Giger RJ
  9. Segal BM
  Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.; Journal of immunology (Baltimore, Md. : 1950). 2015 Aug 3.
• 1. Fernandes KA
  2. Harder JM
  3. John SW
  4. Shrager P
  5. Libby RT
  DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury.; Neurobiology of disease; Vol 69. 2014 Sep.
• 1. Greminger AR
  2. Lee DL
  3. Shrager P
  4. Mayer-Pröschel M
  Gestational Iron Deficiency Differentially Alters the Structure and Function of White and Gray Matter Brain Regions of Developing Rats.; The Journal of nutrition. 2014 Apr 17.
• 1. Einheber S
  2. Meng X
  3. Rubin M
  4. Lam I
  5. Mohandas N
  6. An X
  7. Shrager P
  8. Kissil J
  9. Maurel P
  10. Salzer JL
  The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.; Glia; Vol 61(2). 2013 Feb.
• 1. Einheber S
  2. Maurel P
  3. Meng X
  4. Rubin M
  5. Lam I
  6. Mohandas N
  7. An X
  8. Shrager P
  9. Kissil JA
  10. Salzer J
  The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.; Glia. 2012 Jan 01.
• 1. Winters JJ
  2. Ferguson CJ
  3. Lenk GM
  4. Giger-Mateeva VI
  5. Shrager P
  6. Meisler MH
  7. Giger RJ
  Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 31(48). 2011 Nov 30.
• 1. Winters J
  2. Lenk G
  3. Giger-Mateeva V
  4. Shrager P
  5. Meisler MA
  6. Giger RJ
  Congenital CNS hypomyelination and reduced number of mature oligodendrocytes in the Fig4 null mouse.; Journal of Neuroscience. 2011 Jan 01.
• 1. Raiker SJ
  2. Lee H
  3. Baldwin KT
  4. Duan Y
  5. Shrager P
  6. Giger RJ
  Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 30(37). 2010 Sep 15.
• 1. Feinberg K
  2. Eshed-Eisenbach Y
  3. Frechter S
  4. Amor V
  5. Salomon D
  6. Sabanay H
  7. Dupree JL
  8. Grumet M
  9. Brophy PJ
  10. Shrager P
  11. Peles E
  A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier.; Neuron; Vol 65(4). 2010 Feb 25.
• 1. Feinberg K
  2. Eshed-Eisenbach Y
  3. Frechter S
  4. Amor V
  5. Salomon D
  6. Sabanay H
  7. Dupree JL
  8. Grumet M
  9. Brophy PJ
  10. Shrager P
  11. Peles E
  A glial signal consisting of Gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier.; Neuron. 2010 Jan 01.
• 1. Raiker SJ
  2. Lee H
  3. Duan Y
  4. Koelzer KT
  5. Shrager PA
  6. Giger RJ
  Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.; Journal of Neuroscience; Vol 30, pp. 12432-12445. 2010 Jan 01.
• 1. Lee H
  2. Raiker SJ
  3. Venkatesh K
  4. Geary R
  5. Robak LA
  6. Zhang Y
  7. Yeh HH
  8. Shrager P
  9. Giger RJ
  Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 28(11). 2008 Mar 12.
• 1. Lee H
  2. Raiker S
  3. Venkatesh K
  4. Geary R
  5. Robak LA
  6. Zhang Y
  7. Yeh HH
  8. Shrager PA
  9. Giger RJ
  Synaptic function for the Nogo-66 receptor NgR1: Regulation of dendritic spine morphology and activity-dependent synaptic strength.; Journal of Neuroscience. 2008 Jan 01.
• 1. Hedstrom KL
  2. Xu X
  3. Ogawa Y
  4. Frischknecht R
  5. Seidenbecher CI
  6. Shrager P
  7. Rasband MN
  Neurofascin assembles a specialized extracellular matrix at the axon initial segment.; The Journal of cell biology; Vol 178(5). 2007 Aug 27.
• 1. Hedstrom KL
  2. Xu X
  3. Ogawa Y
  4. Frishnecht R
  5. Seidenbecher CI
  6. Shrager PA
  7. Rasband MN
  Neurofascin assembles a specialized extracellular matrix at the axon initial segment.; Journal of Cell Biology; Vol 178, pp. 875-886. 2007 Jan 01.
• 1. Schafer DP
  2. Custer AW
  3. Shrager P
  4. Rasband MN
  Early events in node of Ranvier formation during myelination and remyelination in the PNS.; Neuron glia biology; Vol 2(2). 2006 May.
• 1. Taveggia C
  2. Zanazzi G
  3. Petrylak A
  4. Yano H
  5. Rosenbluth J
  6. Einheber S
  7. Xu X
  8. Esper RM
  9. Loeb JA
  10. Shrager P
  11. Chao MV
  12. Falls DL
  13. Role L
  14. Salzer JL
  Neuregulin-1 type III determines the ensheathment fate of axons.; Neuron; Vol 47(5). 2005 Sep 1.
• 1. Xu X
  2. Shrager P
  Dependence of axon initial segment formation on Na+ channel expression.; Journal of neuroscience research; Vol 79(4). 2005 Feb 15.
• 1. Chen C
  2. Westenbroek RE
  3. Xu X
  4. Edwards CA
  5. Sorenson DR
  6. Chen Y
  7. McEwen DP
  8. O'Malley HA
  9. Bharucha V
  10. Meadows LS
  11. Knudsen GA
  12. Vilaythong A
  13. Noebels JL
  14. Saunders TL
  15. Scheuer T
  16. Shrager P
  17. Catterall WA
  18. Isom LL
  Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 24(16). 2004 Apr 21.
• 1. Custer AW
  2. Kazarinova-Noyes K
  3. Sakurai T
  4. Xu X
  5. Simon W
  6. Grumet M
  7. Shrager P
  The role of the ankyrin-binding protein NrCAM in node of Ranvier formation.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 23(31). 2003 Nov 5.
• 1. Poliak S
  2. Salomon D
  3. Elhanany H
  4. Sabanay H
  5. Kiernan B
  6. Pevny L
  7. Stewart CL
  8. Xu X
  9. Chiu SY
  10. Shrager P
  11. Furley AJ
  12. Peles E
  Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1.; The Journal of cell biology; Vol 162(6). 2003 Sep 15.
• 1. Chen C
  2. Bharucha V
  3. Chen Y
  4. Westenbroek RE
  5. Brown A
  6. Malhotra JD
  7. Jones D
  8. Avery C
  9. Gillespie PJ
  10. Kazen-Gillespie KA
  11. Kazarinova-Noyes K
  12. Shrager P
  13. Saunders TL
  14. Macdonald RL
  15. Ransom BR
  16. Scheuer T
  17. Catterall WA
  18. Isom LL
  Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits.; Proceedings of the National Academy of Sciences of the United States of America; Vol 99(26). 2002 Dec 24.
• 1. Kazarinova-Noyes K
  2. Shrager P
  Molecular constituents of the node of Ranvier.; Molecular neurobiology; Vol 26(2-3). 2002 Oct.
• 1. Chen C
  2. Bharucha V
  3. Chen Y
  4. Westenbroek RE
  5. Brown A
  6. Malhotra JD
  7. Jones D
  8. Avery C
  9. Gillespie PJ
  10. Kazen-Gillespie KA
  11. Kazarinova-Noyes K
  12. Shrager P
  13. Saunders TL
  14. Macdonald RL
  15. Ransom BR
  16. Scheuer T
  17. Catterall WA
  18. Isom LL
  Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta2-subunits.; Proceedings of the National Academy of Sciences; Vol 99, pp. 17072-17077. 2002 Jan 01.
• 1. Kazarinova-Noyes K
  2. Malhotra JD
  3. McEwen DP
  4. Mattei LN
  5. Berglund EO
  6. Ranscht B
  7. Levinson SR
  8. Schachner M
  9. Shrager P
  10. Isom LL
  11. Xiao ZC
  Contactin associates with Na+ channels and increases their functional expression.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 21(19). 2001 Oct 1.
• 1. Harroch S
  2. Palmeri M
  3. Rosenbluth J
  4. Custer A
  5. Okigaki M
  6. Shrager P
  7. Blum M
  8. Buxbaum JD
  9. Schlessinger J
  No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase beta.; Molecular and cellular biology; Vol 20(20). 2000 Oct.
• 1. Rasband MN
  2. Shrager P
  Ion channel sequestration in central nervous system axons.; The Journal of physiology; Vol 525 Pt 1. 2000 May 15.
• 1. Rasband MN
  2. Trimmer JS
  3. Peles E
  4. Levinson SR
  5. Shrager P
  K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve.; Journal of Neurocytology; Vol 28, pp. 319-331. 2000 Jan 01.
• 1. Poliak S
  2. Gollan L
  3. Martinez R
  4. Custer A
  5. Einheber S
  6. Salzer JL
  7. Trimmer JS
  8. Shrager P
  9. Peles E
  Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels.; Neuron; Vol 24(4). 1999 Dec.
• 1. Rasband MN
  2. Peles E
  3. Trimmer JS
  4. Levinson SR
  5. Lux SE
  6. Shrager P
  Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 19(17). 1999 Sep 1.
• 1. Weber P
  2. Bartsch U
  3. Rasband MN
  4. Czaniera R
  5. Lang Y
  6. Bluethmann H
  7. Margolis RU
  8. Levinson SR
  9. Shrager P
  10. Montag D
  11. Schachner M
  Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 19(11). 1999 Jun 1.
• 1. Rasband MN
  2. Trimmer JS
  3. Peles E
  4. Levinson SR
  5. Shrager P
  K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve.; Journal of neurocytology; Vol 28(4-5). 1999 Apr.
• 1. Vabnick I
  2. Trimmer JS
  3. Schwarz TL
  4. Levinson SR
  5. Risal D
  6. Shrager P
  Dynamic potassium channel distributions during axonal development prevent aberrant firing patterns.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 19(2). 1999 Jan 15.
• 1. Vabnick I
  2. Shrager P
  Ion channel redistribution and function during development of the myelinated axon.; Journal of neurobiology; Vol 37(1). 1998 Oct.
• 1. Novakovic SD
  2. Levinson SR
  3. Schachner M
  4. Shrager P
  Disruption and reorganization of sodium channels in experimental allergic neuritis.; Muscle & nerve; Vol 21(8). 1998 Aug.
• 1. Shrager P
  2. Custer AW
  3. Kazarinova K
  4. Rasband MN
  5. Mattson D
  Nerve conduction block by nitric oxide that is mediated by the axonal environment.; Journal of neurophysiology; Vol 79(2). 1998 Feb.
• 1. Rasband MN
  2. Trimmer JS
  3. Schwarz TL
  4. Levinson SR
  5. Ellisman MH
  6. Schachner M
  7. Shrager P
  Potassium channel distribution, clustering, and function in remyelinating rat axons.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 18(1). 1998 Jan 1.
• 1. Vabnick I
  2. Messing A
  3. Chiu SY
  4. Levinson SR
  5. Schachner M
  6. Roder J
  7. Li C
  8. Novakovic S
  9. Shrager P
  Sodium channel distribution in axons of hypomyelinated and MAG null mutant mice.; Journal of neuroscience research; Vol 50(2). 1997 Oct 15.
• 1. Vabnick I
  2. Novaković SD
  3. Levinson SR
  4. Schachner M
  5. Shrager P
  The clustering of axonal sodium channels during development of the peripheral nervous system.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 16(16). 1996 Aug 15.
• 1. England JD
  2. Levinson SR
  3. Shrager P
  Immunocytochemical investigations of sodium channels along nodal and internodal portions of demyelinated axons.; Microscopy research and technique; Vol 34(5). 1996 Aug 1.
• 1. Novakovic SD
  2. Deerinck TJ
  3. Levinson SR
  4. Shrager P
  5. Ellisman MH
  Clusters of axonal Na+ channels adjacent to remyelinating Schwann cells.; Journal of neurocytology; Vol 25(6). 1996 Jun.