URMC / Labs / Xing Lab / Publications

Publications

1. Zhang D
2. Xu H
3. Qin C
4. Cai K
5. Zhang J
6. Xia X
7. Bi J
8. Zhang L
9. Xing L
10. Liang Q
11. Wang W
Reduced expression of semaphorin 3A in osteoclasts causes lymphatic expansion in a Gorham-Stout disease (GSD) mouse model.; Journal of Zhejiang University. Science. B; Vol 25(1), pp. 38-50. 2024 Jan 15.
1. Wang YJ
2. Zheng Y
3. Cong L
4. Wang P
5. Zhao L
6. Xing L
7. Liu J
8. Xu H
9. Li N
10. Zhao Y
11. Shi Q
12. Liang Q
Lymphatic platelet thrombosis limits bone repair by precluding lymphatic transporting DAMPs.; Research square. 2023 Jan 14.
1. Peng Y
2. Kenney HM
3. de Mesy Bentley KL
4. Xing L
5. Ritchlin CT
6. Schwarz EM
Distinct mast cell subpopulations within and around lymphatic vessels regulate lymph flow and progression of inflammatory-erosive arthritis in TNF-transgenic mice.; Frontiers in immunology; Vol 14, pp. 1275871. 2023 Jan 14.
1. Lin X
2. Zhang H
3. Liu J
4. Wu CL
5. McDavid A
6. Boyce BF
7. Xing L
Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential.; Frontiers in molecular biosciences; Vol 9. 2022.
1. Sun S
2. Tao J
3. Sedghizadeh PP
4. Cherian P
5. Junka AF
6. Sodagar E
7. Xing L
8. Boeckman RK
9. Srinivasan V
10. Yao Z
11. Boyce BF
12. Lipe B
13. Neighbors JD
14. Russell G
15. McKenna CE
16. Ebetino FH
Bisphosphonates for delivering drugs to bone.; British journal of pharmacology. 2020 Sep 02.
1. Wang H
2. Chen Y
3. Li W
4. Sun L
5. Chen H
6. Yang Q
7. Zhang H
8. Zhang W
9. Yuan H
10. Zhang H
11. Xing L
12. Sun W
Effect of VEGFC on lymph flow and inflammation-induced alveolar bone loss.; The Journal of pathology; Vol 251(3). 2020 Jul.
1. Yuan G
2. Yang S
3. Ng A
4. Fu C
5. Oursler MJ
6. Xing L
7. Yang S
RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis.; iScience; Vol 23(6). 2020 Jun 26.
1. Lin X
2. Zhang H
3. Boyce BF
4. Xing L
Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH.; The Journal of biological chemistry. 2020 Jun 25.
1. Xing L
2. Ebetino FH
3. Boeckman RK
4. Srinivasan V
5. Tao J
6. Sawyer TK
7. Li J
8. Yao Z
9. Boyce BF
Targeting anti-cancer agents to bone using bisphosphonates.; Bone. 2020 Jun 22.
1. Chen J
2. Wang L
3. Xu H
4. Xing L
5. Zhuang Z
6. Zheng Y
7. Li X
8. Wang C
9. Chen S
10. Guo Z
11. Liang Q
12. Wang Y
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.; Nature communications; Vol 11(1). 2020 Jun 22.
1. Li J
2. Yi X
3. Yao Z
4. Chakkalakal JV
5. Xing L
6. Boyce BF
TNF receptor-associated factor 6 mediates TNFα-induced skeletal muscle atrophy in mice during aging.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020 Apr 08.
1. Bell RD
2. Slattery PN
3. Wu EK
4. Xing L
5. Ritchlin CT
6. Schwarz EM
iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis.; Arthritis research & therapy; Vol 21(1). 2019 Nov 14.
1. Wang H
2. Zhang H
3. Srinivasan V
4. Tao J
5. Sun W
6. Lin X
7. Wu T
8. Boyce BF
9. Ebetino FH
10. Boeckman RK
11. Xing L
Targeting Bortezomib to Bone Increases its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2019 Oct 14.
1. Liang Q
2. Zhang L
3. Wood RW
4. Ji RC
5. Boyce BF
6. Schwarz EM
7. Wang Y
8. Xing L
RelB regulates lymphatic endothelial cells during vessel maturation and is required for lymphatic vessel function in adult mice.; The American journal of pathology. 2019 Sep 17.
1. Li J
2. Ayoub A
3. Xiu Y
4. Yin X
5. Sanders JO
6. Mesfin A
7. Xing L
8. Yao Z
9. Boyce BF
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.; Nature communications; Vol 10(1). 2019 Jun 26.
1. Sun W
2. Meednu N
3. Rosenberg A
4. Rangel-Moreno J
5. Wang V
6. Glanzman J
7. Owen T
8. Zhou X
9. Zhang H
10. Boyce BF
11. Anolik JH
12. Xing L
B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.; Nature communications; Vol 9(1). 2018 Dec 03.
1. Ye H
2. Adane B
3. Khan N
4. Alexeev E
5. Nusbacher N
6. Minhajuddin M
7. Stevens BM
8. Winters AC
9. Lin X
10. Ashton JM
11. Purev E
12. Xing L
13. Pollyea DA
14. Lozupone CA
15. Serkova NJ
16. Colgan SP
17. Jordan CT
Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells.; Cancer cell. 2018 Sep 18.
1. Wang H
2. Xiao L
3. Tao J
4. Srinivasan V
5. Boyce BF
6. Ebetino FH
7. Oyajobi BO
8. Boeckman RK
9. Xing L
Synthesis of a Bone-Targeted Bortezomib with In Vivo Anti-Myeloma Effects in Mice.; Pharmaceutics; Vol 10(3). 2018 Sep 10.
1. Wang W
2. Lin X
3. Xu H
4. Sun W
5. Bouta EM
6. Zuscik MJ
7. Chen D
8. Schwarz EM
9. Xing L
Bortezomib Attenuates Joint Tissue Damage in a Mouse Model of Experimental Post-Traumatic Osteoarthritis, which is Associated with Improved Synovial Lymphatic Function.; Arthritis & rheumatology (Hoboken, N.J.). 2018 Aug 25.
1. Paine A
2. Woeller CF
3. Zhang H
4. de la Luz Garcia-Hernandez M
5. Huertas N
6. Xing L
7. Phipps RP
8. Ritchlin CT
Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 32(6). 2018 Jun.
1. Bouta EM
2. Bell RD
3. Rahimi H
4. Xing L
5. Wood RW
6. Bingham CO
7. Ritchlin CT
8. Schwarz EM
Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis.; Nature reviews. Rheumatology; Vol 14(2). 2018 Feb.
1. Boyce BF
2. Li J
3. Xing L
4. Yao Z
Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption.; Frontiers in immunology; Vol 9. 2018.
1. Zhang L
2. Chang J
3. Zhao Y
4. Xu H
5. Wang T
6. Li Q
7. Xing L
8. Huang J
9. Wang Y
10. Liang Q
Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis.; International journal of nanomedicine; Vol 13. 2018.
1. Sun W
2. Zhang H
3. Wang H
4. Chiu YG
5. Wang M
6. Ritchlin CT
7. Kiernan A
8. Boyce BF
9. Xing L
Targeting Notch-Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(7). 2017 Jul.
1. Lawal RA
2. Zhou X
3. Batey K
4. Hoffman CM
5. Georger MA
6. Radtke F
7. Hilton MJ
8. Xing L
9. Frisch BJ
10. Calvi LM
The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(6). 2017 Jun.
1. Xing L
2. Higuma T
3. Wang Z
4. Aguirre AD
5. Mizuno K
6. Takano M
7. Dauerman HL
8. Park SJ
9. Jang Y
10. Kim CJ
11. Kim SJ
12. Choi SY
13. Itoh T
14. Uemura S
15. Lowe H
16. Walters DL
17. Barlis P
18. Lee S
19. Lerman A
20. Toma C
21. Tan JWC
22. Yamamoto E
23. Bryniarski K
24. Dai J
25. Zanchin T
26. Zhang S
27. Yu B
28. Lee H
29. Fujimoto J
30. Fuster V
31. Jang IK
Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.; Journal of the American College of Cardiology; Vol 69(20). 2017 May 23.
1. Huang QQ
2. Birkett R
3. Doyle RE
4. Haines GK
5. Perlman H
6. Shi B
7. Homan P
8. Xing L
9. Pope RM
Association of Increased F4/80(high) Macrophages With Suppression of Serum-Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells.; Arthritis & rheumatology (Hoboken, N.J.). 2017 May 16.
1. Wang W
2. Wang H
3. Zhou X
4. Li X
5. Sun W
6. Dellinger M
7. Boyce BF
8. Xing L
Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(5). 2017 May.
1. Liu J
2. Li X
3. Zhang H
4. Gu R
5. Wang Z
6. Gao Z
7. Xing L
Ubiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteins.; Bone & joint research; Vol 6(3). 2017 Mar.
1. Li X
2. Sun W
3. Li J
4. Wang M
5. Zhang H
6. Pei L
7. Boyce BF
8. Wang Z
9. Xing L
Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid.; Scientific reports; Vol 7. 2017 Feb 01.
1. Bouta EM
2. Kuzin I
3. de Mesy Bentley K
4. Wood RW
5. Rahimi H
6. Ji RC
7. Ritchlin CT
8. Bottaro A
9. Xing L
10. Schwarz EM
Treatment of Tumor Necrosis Factor-Transgenic Mice With Anti-Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress.; Arthritis & rheumatology (Hoboken, N.J.). 2017 Jan 24.
1. Xu H
2. Bouta EM
3. Wood RW
4. Schwarz EM
5. Wang Y
6. Xing L
Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis.; Bone research; Vol 5. 2017.
1. Li J
2. Chen Y
3. Zhang L
4. Xing L
5. Xu H
6. Wang Y
7. Shi Q
8. Liang Q
Total saponins of panaxnotoginseng promotes lymphangiogenesis by activation VEGF-C expression of lymphatic endothelial cells.; Journal of ethnopharmacology; Vol 193. 2016 Dec 04.
1. Huang QQ
2. Hossain MM
3. Sun W
4. Xing L
5. Pope RM
6. Jin JP
Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice.; American journal of physiology. Cell physiology; Vol 311(4). 2016 Oct 01.
1. Rahimi H
2. Bell R
3. Bouta EM
4. Wood RW
5. Xing L
6. Ritchlin CT
7. Schwarz EM
Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential.; Arthritis research & therapy; Vol 18. 2016 Sep 01.
1. Zhang H
2. Sun W
3. Li X
4. Wang M
5. Boyce BF
6. Hilton MJ
7. Xing L
Use of Hes1-GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation.; Bone; Vol 90. 2016 Sep.
1. Meednu N
2. Zhang H
3. Owen T
4. Sun W
5. Wang V
6. Cistrone C
7. Rangel-Moreno J
8. Xing L
9. Anolik JH
Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis.; Arthritis & rheumatology (Hoboken, N.J.); Vol 68(4). 2016 Apr.
1. Liang Q
2. Ju Y
3. Chen Y
4. Wang W
5. Li J
6. Zhang L
7. Xu H
8. Wood RW
9. Schwarz EM
10. Boyce BF
11. Wang Y
12. Xing L
Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice.; Arthritis research & therapy; Vol 18. 2016 Mar 12.
1. Chen Y
2. Li J
3. Li Q
4. Wang T
5. Xing L
6. Xu H
7. Wang Y
8. Shi Q
9. Zhou Q
10. Liang Q
Du-Huo-Ji-Sheng-Tang Attenuates Inflammation of TNF-Tg Mice Related to Promoting Lymphatic Drainage Function.; Evidence-based complementary and alternative medicine : eCAM; Vol 2016. 2016.
1. Liang QQ
2. Shi Q
3. Wood RW
4. Xing LP
5. Wang YJ
Peri-articular lymphatic system and "Bi" theory of Chinese medicine in the pathogenesis and treatment of arthritis.; Chinese journal of integrative medicine; Vol 21(9). 2015 Sep.
1. Shu L
2. Beier E
3. Sheu T
4. Zhang H
5. Zuscik MJ
6. Puzas EJ
7. Boyce BF
8. Mooney RA
9. Xing L
High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment.; Calcified tissue international; Vol 96(4). 2015 Apr.
1. Boyce BF
2. Xiu Y
3. Li J
4. Xing L
5. Yao Z
NF-κB-Mediated Regulation of Osteoclastogenesis.; Endocrinology and metabolism (Seoul, Korea); Vol 30(1). 2015 Mar 27.
1. Bouta EM
2. Li J
3. Ju Y
4. Brown EB
5. Ritchlin CT
6. Xing L
7. Schwarz EM
The Role of the Lymphatic System in Inflammatory-Erosive Arthritis.; Seminars in cell & developmental biology. 2015 Jan 15.
1. Wang Z
2. Wang J
3. Li X
4. Xing L
5. Ding Y
6. Shi P
7. Zhang Y
8. Guo S
9. Shu X
10. Shan B
Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2.; International journal of oncology; Vol 45(4). 2014 Oct.
1. Cui HB
2. Ge HE
3. Bai XY
4. Zhang W
5. Zhang YY
6. Wang J
7. Li X
8. Xing LP
9. Guo SH
10. Wang ZY
Effect of neoadjuvant chemotherapy combined with hyperthermic intraperitoneal perfusion chemotherapy on advanced gastric cancer.; Experimental and therapeutic medicine; Vol 7(5). 2014 May.
1. Yao Z
2. Li Y
3. Yin X
4. Dong Y
5. Xing L
6. Boyce BF
NF-κB RelB negatively regulates osteoblast differentiation and bone formation.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 29(4). 2014 Apr.
1. Juneja SC
2. Vonica A
3. Zeiss C
4. Lezon-Geyda K
5. Yatsula B
6. Sell DR
7. Monnier VM
8. Lin S
9. Ardito T
10. Eyre D
11. Reynolds D
12. Yao Z
13. Awad HA
14. Yu H
15. Wilson M
16. Honnons S
17. Boyce BF
18. Xing L
19. Zhang Y
20. Perkins AS
Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.; Bone; Vol 60. 2014 Mar.
1. Shi J
2. Liang Q
3. Zuscik M
4. Shen J
5. Chen D
6. Xu H
7. Wang YJ
8. Chen Y
9. Wood RW
10. Li J
11. Boyce BF
12. Xing L
Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice.; Arthritis & rheumatology (Hoboken, N.J.); Vol 66(3). 2014 Mar.
1. Wang B
2. Jin H
3. Zhu M
4. Li J
5. Zhao L
6. Zhang Y
7. Tang D
8. Xiao G
9. Xing L
10. Boyce BF
11. Chen D
Chondrocyte β-catenin signaling regulates postnatal bone remodeling through modulation of osteoclast formation in a murine model.; Arthritis & rheumatology (Hoboken, N.J.); Vol 66(1). 2014 Jan.
1. Brown ML
2. Yukata K
3. Farnsworth CW
4. Chen DG
5. Awad H
6. Hilton MJ
7. O'Keefe RJ
8. Xing L
9. Mooney RA
10. Zuscik MJ
Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.; PloS one; Vol 9(6). 2014.