URMC / Labs / Yarovinsky Lab / Publications

Publications

1. Martin AT
2. Giri S
3. Safronova A
4. Eliseeva SI
5. Kwok SF
6. Yarovinsky F
Parasite-induced IFN-γ regulates host defense via CD115 and mTOR-dependent mechanism of tissue-resident macrophage death.; PLoS pathogens; Vol 20(2), pp. e1011502. 2024 Feb 20.
1. Araujo A
2. Safronova A
3. Burger E
4. López-Yglesias A
5. Giri S
6. Camanzo ET
7. Martin AT
8. Grivennikov S
9. Yarovinsky F
IFN-γ mediates Paneth cell death via suppression of mTOR.; eLife; Vol 10. 2021 Oct 11.
1. López-Yglesias AH
2. Burger E
3. Camanzo E
4. Martin AT
5. Araujo AM
6. Kwok SF
7. Yarovinsky F
T-bet-dependent ILC1- and NK cell-derived IFN-γ mediates cDC1-dependent host resistance against Toxoplasma gondii.; PLoS pathogens; Vol 17(1). 2021 Jan 19.
1. Coombs RS
2. Blank ML
3. English ED
4. Adomako-Ankomah Y
5. Urama IS
6. Martin AT
7. Yarovinsky F
8. Boyle JP
Immediate interferon gamma induction determines murine host compatibility differences between Toxoplasma gondii and Neospora caninum.; Infection and immunity. 2020 Feb 03.
1. López-Yglesias AH
2. Camanzo E
3. Martin AT
4. Araujo AM
5. Yarovinsky F
TLR11-independent inflammasome activation is critical for CD4+ T cell-derived IFN-γ production and host resistance to Toxoplasma gondii.; PLoS pathogens; Vol 15(6). 2019 Jun 13.
1. Safronova A
2. Araujo A
3. Camanzo ET
4. Moon TJ
5. Elliott MR
6. Beiting DP
7. Yarovinsky F
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii.; Nature immunology. 2018 Nov 19.
1. Burger E
2. Araujo A
3. López-Yglesias A
4. Rajala MW
5. Geng L
6. Levine B
7. Hooper LV
8. Burstein E
9. Yarovinsky F
Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation.; Cell host & microbe; Vol 23(2). 2018 Feb 14.
1. López-Yglesias AH
2. Burger E
3. Araujo A
4. Martin AT
5. Yarovinsky F
T-bet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection.; Mucosal immunology. 2018 Jan 03.
1. Burger E
2. Araujo A
3. López-Yglesias A
4. Rajala MW
5. Geng L
6. Levine B
7. Hooper LV
8. Burstein E
9. Yarovinsky F
Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation; Cell Host & Microbe. 2018 Jan 01.
1. Song J
2. Wilhelm CL
3. Wangdi T
4. Maira-Litran T
5. Lee SJ
6. Raetz M
7. Sturge CR
8. Mirpuri J
9. Pei J
10. Grishin NV
11. McSorley SJ
12. Gewirtz AT
13. Bäumler AJ
14. Pier GB
15. Galán JE
16. Yarovinsky F
Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi.; Cell; Vol 164(5). 2016 Feb 25.
1. Sturge CR
2. Burger E
3. Raetz M
4. Hooper LV
5. Yarovinsky F
Cutting Edge: Developmental Regulation of IFN-γ Production by Mouse Neutrophil Precursor Cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 195(1). 2015 Jul 01.
1. Oh JZ
2. Ravindran R
3. Chassaing B
4. Carvalho FA
5. Maddur MS
6. Bower M
7. Hakimpour P
8. Gill KP
9. Nakaya HI
10. Yarovinsky F
11. Sartor RB
12. Gewirtz AT
13. Pulendran B
TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination.; Immunity; Vol 41(3). 2014 Sep 18.
1. Wilhelm CL
2. Yarovinsky F
Apicomplexan infections in the gut.; Parasite immunology; Vol 36(9). 2014 Sep.
1. Sturge CR
2. Yarovinsky F
Complex immune cell interplay in the gamma interferon response during Toxoplasma gondii infection.; Infection and immunity; Vol 82(8). 2014 Aug.
1. Li H
2. Chan L
3. Bartuzi P
4. Melton SD
5. Weber A
6. Ben-Shlomo S
7. Varol C
8. Raetz M
9. Mao X
10. Starokadomskyy P
11. van Sommeren S
12. Mokadem M
13. Schneider H
14. Weisberg R
15. Westra HJ
16. Esko T
17. Metspalu A
18. Kumar V
19. Faubion WA
20. Yarovinsky F
21. Hofker M
22. Wijmenga C
23. Kracht M
24. Franke L
25. Aguirre V
26. Weersma RK
27. Gluck N
28. van de Sluis B
29. Burstein E
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.; Gastroenterology; Vol 147(1). 2014 Jul.
1. Yarovinsky F
Innate immunity to Toxoplasma gondii infection.; Nature reviews. Immunology; Vol 14(2). 2014 Feb.
1. Mirpuri J
2. Raetz M
3. Sturge CR
4. Wilhelm CL
5. Benson A
6. Savani RC
7. Hooper LV
8. Yarovinsky F
Proteobacteria-specific IgA regulates maturation of the intestinal microbiota.; Gut microbes; Vol 5(1). 2014 Jan.
1. Raetz M
2. Kibardin A
3. Sturge CR
4. Pifer R
5. Li H
6. Burstein E
7. Ozato K
8. Larin S
9. Yarovinsky F
Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin.; Journal of immunology (Baltimore, Md. : 1950); Vol 191(9). 2013 Nov 01.
1. Sturge CR
2. Benson A
3. Raetz M
4. Wilhelm CL
5. Mirpuri J
6. Vitetta ES
7. Yarovinsky F
TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens.; Proceedings of the National Academy of Sciences of the United States of America; Vol 110(26). 2013 Jun 25.
1. Raetz M
2. Hwang SH
3. Wilhelm CL
4. Kirkland D
5. Benson A
6. Sturge CR
7. Mirpuri J
8. Vaishnava S
9. Hou B
10. Defranco AL
11. Gilpin CJ
12. Hooper LV
13. Yarovinsky F
Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells.; Nature immunology; Vol 14(2). 2013 Feb.
1. Hwang SH
2. Lee H
3. Yamamoto M
4. Jones LA
5. Dayalan J
6. Hopkins R
7. Zhou XJ
8. Yarovinsky F
9. Connolly JE
10. Curotto de Lafaille MA
11. Wakeland EK
12. Fairhurst AM
B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice.; Journal of immunology (Baltimore, Md. : 1950); Vol 189(12). 2012 Dec 15.
1. Grivennikov SI
2. Wang K
3. Mucida D
4. Stewart CA
5. Schnabl B
6. Jauch D
7. Taniguchi K
8. Yu GY
9. Osterreicher CH
10. Hung KE
11. Datz C
12. Feng Y
13. Fearon ER
14. Oukka M
15. Tessarollo L
16. Coppola V
17. Yarovinsky F
18. Cheroutre H
19. Eckmann L
20. Trinchieri G
21. Karin M
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.; Nature; Vol 491(7423). 2012 Nov 08.
1. Kirkland D
2. Benson A
3. Mirpuri J
4. Pifer R
5. Hou B
6. DeFranco AL
7. Yarovinsky F
B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.; Immunity; Vol 36(2). 2012 Feb 24.
1. Benson A
2. Murray S
3. Divakar P
4. Burnaevskiy N
5. Pifer R
6. Forman J
7. Yarovinsky F
Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism.; Journal of immunology (Baltimore, Md. : 1950); Vol 188(2). 2012 Jan 15.
1. Mirpuri J
2. Yarovinsky F
IL-6 signaling SOCS critical for IL-12 host response to Toxoplasma gondii.; Future microbiology; Vol 7(1). 2012 Jan.
1. Mirpuri J
2. Sotnikov I
3. Myers L
4. Denning TL
5. Yarovinsky F
6. Parkos CA
7. Denning PW
8. Louis NA
Lactobacillus rhamnosus (LGG) regulates IL-10 signaling in the developing murine colon through upregulation of the IL-10R2 receptor subunit.; PloS one; Vol 7(12). 2012.
1. Broadhurst MJ
2. Ardeshir A
3. Kanwar B
4. Mirpuri J
5. Gundra UM
6. Leung JM
7. Wiens KE
8. Vujkovic-Cvijin I
9. Kim CC
10. Yarovinsky F
11. Lerche NW
12. McCune JM
13. Loke P
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.; PLoS pathogens; Vol 8(11). 2012.
1. McFadden N
2. Bailey D
3. Carrara G
4. Benson A
5. Chaudhry Y
6. Shortland A
7. Heeney J
8. Yarovinsky F
9. Simmonds P
10. Macdonald A
11. Goodfellow I
Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4.; PLoS pathogens; Vol 7(12). 2011 Dec.
1. Butcher BA
2. Fox BA
3. Rommereim LM
4. Kim SG
5. Maurer KJ
6. Yarovinsky F
7. Herbert DR
8. Bzik DJ
9. Denkers EY
Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.; PLoS pathogens; Vol 7(9). 2011 Sep.
1. Pifer R
2. Yarovinsky F
Innate responses to Toxoplasma gondii in mice and humans.; Trends in parasitology; Vol 27(9). 2011 Sep.
1. Ismail AS
2. Severson KM
3. Vaishnava S
4. Behrendt CL
5. Yu X
6. Benjamin JL
7. Ruhn KA
8. Hou B
9. DeFranco AL
10. Yarovinsky F
11. Hooper LV
Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface.; Proceedings of the National Academy of Sciences of the United States of America; Vol 108(21). 2011 May 24.
1. Pifer R
2. Benson A
3. Sturge CR
4. Yarovinsky F
UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii.; The Journal of biological chemistry; Vol 286(5). 2011 Feb 04.
1. Hou B
2. Benson A
3. Kuzmich L
4. DeFranco AL
5. Yarovinsky F
Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors.; Proceedings of the National Academy of Sciences of the United States of America; Vol 108(1). 2011 Jan 04.
1. Becker AM
2. Blevins JS
3. Tomson FL
4. Eitson JL
5. Medeiros JJ
6. Yarovinsky F
7. Norgard MV
8. van Oers NS
Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifs.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(12). 2010 Jun 15.
1. Wilson MS
2. Feng CG
3. Barber DL
4. Yarovinsky F
5. Cheever AW
6. Sher A
7. Grigg M
8. Collins M
9. Fouser L
10. Wynn TA
Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(8). 2010 Apr 15.
1. Bailey D
2. Karakasiliotis I
3. Vashist S
4. Chung LM
5. Rees J
6. Reese J
7. McFadden N
8. Benson A
9. Yarovinsky F
10. Simmonds P
11. Goodfellow I
Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.; Journal of virology; Vol 84(6). 2010 Mar.
1. Sassi A
2. Brichacek B
3. Hieny S
4. Yarovinsky F
5. Golding H
6. Grivel JC
7. Sher A
8. Margolis L
Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo.; Microbes and infection; Vol 11(14-15). 2009 Dec.
1. Benson A
2. Pifer R
3. Behrendt CL
4. Hooper LV
5. Yarovinsky F
Gut commensal bacteria direct a protective immune response against Toxoplasma gondii.; Cell host & microbe; Vol 6(2). 2009 Aug 20.
1. Sanders CJ
2. Franchi L
3. Yarovinsky F
4. Uematsu S
5. Akira S
6. Núñez G
7. Gewirtz AT
Induction of adaptive immunity by flagellin does not require robust activation of innate immunity.; European journal of immunology; Vol 39(2). 2009 Feb.
1. Yarovinsky F
2. Hieny S
3. Sher A
Recognition of Toxoplasma gondii by TLR11 prevents parasite-induced immunopathology.; Journal of immunology (Baltimore, Md. : 1950); Vol 181(12). 2008 Dec 15.
1. Yarovinsky F
Toll-like receptors and their role in host resistance to Toxoplasma gondii.; Immunology letters; Vol 119(1-2). 2008 Aug 15.
1. Pepper M
2. Dzierszinski F
3. Wilson E
4. Tait E
5. Fang Q
6. Yarovinsky F
7. Laufer TM
8. Roos D
9. Hunter CA
Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines.; Journal of immunology (Baltimore, Md. : 1950); Vol 180(9). 2008 May 01.
1. Plattner F
2. Yarovinsky F
3. Romero S
4. Didry D
5. Carlier MF
6. Sher A
7. Soldati-Favre D
Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.; Cell host & microbe; Vol 3(2). 2008 Feb 14.
1. Yarovinsky F
2. Kanzler H
3. Hieny S
4. Coffman RL
5. Sher A
Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response.; Immunity; Vol 25(4). 2006 Oct.
1. Yarovinsky F
2. Sher A
Toll-like receptor recognition of Toxoplasma gondii.; International journal for parasitology; Vol 36(3). 2006 Mar.
1. Golding H
2. Khurana S
3. Yarovinsky F
4. King LR
5. Abdoulaeva G
6. Antonsson L
7. Owman C
8. Platt EJ
9. Kabat D
10. Andersen JF
11. Sher A
CCR5 N-terminal region plays a critical role in HIV-1 inhibition by Toxoplasma gondii-derived cyclophilin-18.; The Journal of biological chemistry; Vol 280(33). 2005 Aug 19.
1. Yarovinsky F
2. Zhang D
3. Andersen JF
4. Bannenberg GL
5. Serhan CN
6. Hayden MS
7. Hieny S
8. Sutterwala FS
9. Flavell RA
10. Ghosh S
11. Sher A
TLR11 activation of dendritic cells by a protozoan profilin-like protein.; Science (New York, N.Y.); Vol 308(5728). 2005 Jun 10.
1. Kurosaka K
2. Chen Q
3. Yarovinsky F
4. Oppenheim JJ
5. Yang D
Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.; Journal of immunology (Baltimore, Md. : 1950); Vol 174(10). 2005 May 15.
1. Yarovinsky F
2. Andersen JF
3. King LR
4. Caspar P
5. Aliberti J
6. Golding H
7. Sher A
Structural determinants of the anti-HIV activity of a CCR5 antagonist derived from Toxoplasma gondii.; The Journal of biological chemistry; Vol 279(51). 2004 Dec 17.
1. Abe K
2. Yarovinsky FO
3. Murakami T
4. Shakhov AN
5. Tumanov AV
6. Ito D
7. Drutskaya LN
8. Pfeffer K
9. Kuprash DV
10. Komschlies KL
11. Nedospasov SA
Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo.; Blood; Vol 101(4). 2003 Feb 15.