Keith Nehrke
Keith Nehrke
| Grant No./PI | Description |
|---|---|
| NSF IOS-1352836 K. Nehrke PI |
Mitochondrial Regulation of Calcium Signaling in C. elegans 05/01/14-04/30/18 |
| NIH R01-GM087483 K. Nehrke and P. Brookes, co-PIs |
C. Elegans and Mitochondrial K+ Channels 01/01/10-12/31/17 |
| NIH R01-HL127891 K. Nehrke and P. Brookes, co-PIs |
The Role of the Mitochondrial UPR in Ischemic Protection 04/01/15-02/29/19 |
Our laboratory studies mechanisms by which external cues regulate systems functions. Integrative approaches in the nematode C. elegans and mammalian cardiac models focus on how membrane electrolyte flux and pH regulation exhibit environmental responses to inform metabolism, physiology, and ultimately survival. Funded projects center around the role of mitochondria in oscillatory calcium signaling, metabolic plasticity, and sensitivity to ischemia-reperfusion injury.
