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URMC / Labs / Refaai Lab / Projects / Platelet Lysate (PL) Product As a New Means For Topical Application in Wounds

 

Platelet Lysate (PL) Product As a New Means For Topical Application in Wounds

We obtained a patent for developing a new, procoagulable, platelet lysate product to be potentially administered topically for bleeds in both trauma and surgical settings. We are using thromboelastography (TEG), platelet and whole blood aggregation studies, thrombin generation assay (TGA), as well as flow cytometry to evaluate our product’s effectiveness compared to standard platelet products.

Below is a plot of TGA tracings of platelet lysate compared to stored platelets and normal donor platelet rich plasma (PRP).

control plasmas

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