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UR Medicine Faculty
The University of Rochester Medical Faculty Group
(URMFG) consists of over 900 specialist and primary care providers spanning 19
departments.
URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner
Accountable Health Partners (AHP) is a network of
over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the
region. AHP offers a full range of care.
As a neonatologist, Dr. Scheible's first and foremost goal is to provide excellent clinical care to her patients. She believes it is critical to work collaboratively with parents and bedside care providers to achieve the best outcomes for our babies, even in highly complex clinical situations. Sh...
As a neonatologist, Dr. Scheible's first and foremost goal is to provide excellent clinical care to her patients. She believes it is critical to work collaboratively with parents and bedside care providers to achieve the best outcomes for our babies, even in highly complex clinical situations. She encourages her care team to incorporate parental concerns into their daily assessment. By doing so, they can have a complete understanding of the patient's condition not just based on objective data available to us, but also the more subtle, and difficult to gather, "intuition" that only a parent can provide.
As part of the extracorporeal membrane oxygenation team (ECMO) team, Dr. Scheible has a special interest in caring for babies with persistent pulmonary hypertension, who struggle with adapting their circulation to an ex-utero environment. The complex, labile physiology and individual variability that such babies experience is exceptionally challenging, and requires an intensive, interdisciplinary approach to help them transition.
She feels that as neonatologists her job is not to just address the immediate problem, but also understand the long-term risks and benefits of each of our treatments. For her, balancing these short and long term goals, in cooperation with the parents and care team, is the most difficult and rewarding aspect of being a Neonatologist.
Dr. Scheible has received the "Patient and Family Centered Care Award" and holds "Bronze Star" level which is direct recognition from the families and patients in which she serves.
Faculty Appointments
Associate Professor
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Department of Pediatrics, Neonatology (SMD)
Dean's Associate Professorship
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Department of Pediatrics (SMD)
Associate Professor
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Department of Microbiology and Immunology (SMD) - Joint
Credentials
Residency & Fellowship
Fellowship, Neonatology, University of Rochester Medical Center. 2007 - 2010
Residency, Pediatrics, University of Rochester Medical Center. 2005 - 2007
Internship, Pediatrics, University of Rochester Medical Center. 2004 - 2005
Education
MD | University of Rochester School of Medicine/Dentistry (USA).2004
Awards
American Thoracic Society Abstract Award.2017
University of Rochester Bronze Star.2014
Patient-and Family-Centered Care Award.2013
Patient-and Family-Centered Care Award.2012
University of Rochester Strong Star.2011 - 2016
Pediatric Research Society, Young Investigator.2011
Ruth L. Kirschstein National Research Service Award, (T32, Francis Gigliotti).2008 - 2011
Janet M. Glascow Memorial Achievement Award.2004
Summer Fellowship in Anesthesiology.2000
Outstanding Graduate in the Faculty of Arts and Letters.1993
Lucia Maria Haupt Award in Anthropology.1993
Kreyer Prize for Excellence in German.1991
Research
Advanced NICU care has improved survival of very premature infants, but their improved survival is accompanied by long-term complications such as impaired lung function. Infants born prematurely are highly susceptible to recurrent, severe respiratory viruses, suggesting a state of immune deficiency,...
Advanced NICU care has improved survival of very premature infants, but their improved survival is accompanied by long-term complications such as impaired lung function. Infants born prematurely are highly susceptible to recurrent, severe respiratory viruses, suggesting a state of immune deficiency, specifically T cell immunity. They also suffer from diseases characterized by chronic inflammation associated with T cell activation, including bronchopulmonary dysplasia. This clinical paradox (T cells able to activate but not protect) is not well explained.
Our lab is interested in understanding the specific ways in which premature birth disrupts normal T cell development, and the impact of abnormal T cell development on a premature infant's clinical outcomes. Our lab primarily uses high parameter flow cytometric and high-throughput sequencing approaches to interrogate T cell receptor, cytokine signaling and functional differences that are intrinsic to T cells in various stages of fetal development. We work closely with investigators in Neonatology, Obstetrics, Infectious Diseases, Microbiology, Immunology, Genetics, Biostatistics and Computational Biology to understand in vitro T cell behavior in the context of longitudinal, translational human studies, including the Prematurity and Respiratory Outcomes Program and Respiratory Pathogens Research Center.
Dr. Scheible is a member of the Society for Pediatric Research and fellow, of the American Academy of Pediatrics.
Meléndez DC, Laniewski N, Jusko TA, Qiu X, Paige Lawrence B, Rivera-Núñez Z, Brunner J, Best M, Macomber A, Leger A, Kannan K, Miller RK, Barrett ES, O'Connor TG, Scheible K
medRxiv : the preprint server for health sciences.. 2024 November 18 Epub 11/18/2024.
O'Connor T, Best M, Brunner J, Ciesla AA, Cunning A, Kapula N, Kautz A, Khoury L, Macomber A, Meng Y, Miller RK, Murphy H, Salafia CM, Vallejo Sefair A, Serrano J, Barrett E,
BMJ open.. 2021 April 111 (4):e044798. Epub 04/01/2021.
Steiner LA, Getman M, Schiralli Lester GM, Iqbal MA, Katzman P, Szafranski P, Stankiewicz P, Bhattacharya S, Mariani T, Pryhuber G, Lin X, Young JL, Dean DA, Scheible K
Journal of medical genetics.. 2020 May 57 (5):296-300. Epub 10/29/2019.
Grier A, McDavid A, Wang B, Qiu X, Java J, Bandyopadhyay S, Yang H, Holden-Wiltse J, Kessler HA, Gill AL, Huyck H, Falsey AR, Topham DJ, Scheible KM, Caserta MT, Pryhuber GS, Gill SR
Microbiome.. 2018 October 266 (1):193. Epub 10/26/2018.
Grier A, Qiu X, Bandyopadhyay S, Holden-Wiltse J, Kessler HA, Gill AL, Hamilton B, Huyck H, Misra S, Mariani TJ, Ryan RM, Scholer L, Scheible KM, Lee YH, Caserta MT, Pryhuber GS, Gill SR
Microbiome.. 2017 December 115 (1):158. Epub 12/11/2017.
Szafranski P, Gambin T, Dharmadhikari AV, Akdemir KC, Jhangiani SN, Schuette J, Godiwala N, Yatsenko SA, Sebastian J, Madan-Khetarpal S, Surti U, Abellar RG, Bateman DA, Wilson AL, Markham MH, Slamon J, Santos-Simarro F, Palomares M, Nevado J, Lapunzina P, Chung BH, Wong WL, Chu YW, Mok GT, Kerem E, Reiter J, Ambalavanan N, Anderson SA, Kelly DR, Shieh J, Rosenthal TC, Scheible K, Steiner L, Iqbal MA, McKinnon ML, Hamilton SJ, Schlade-Bartusiak K, English D, Hendson G, Roeder ER, DeNapoli TS, Littlejohn RO, Wolff DJ, Wagner CL, Yeung A, Francis D, Fiorino EK, Edelman M, Fox J, Hayes DA, Janssens S, De Baere E, Menten B, Loccufier A, Vanwalleghem L, Moerman P, Sznajer Y, Lay AS, Kussmann JL, Chawla J, Payton DJ, Phillips GE, Brosens E, Tibboel D, de Klein A, Maystadt I, Fisher R, Sebire N, Male A, Chopra M, Pinner J, Malcolm G, Peters G, Arbuckle S, Lees M, Mead Z, Quarrell O, Sayers R, Owens M, Shaw-Smith C, Lioy J, McKay E, de Leeuw N, Feenstra I, Spruijt L, Elmslie F, Thiruchelvam T, Bacino CA, Langston C, Lupski JR, Sen P, Popek E, Stankiewicz P
Human genetics.. 2016 May 135 (5):569-586. Epub 04/12/2016.
Scheible K, Zhang G, Baer J, Azadniv M, Lambert K, Pryhuber G, Treanor JJ, Topham DJ
Vaccine.. 2011 March 329 (11):2159-68. Epub 01/04/2011.
T-Lymphocytes in human infants with bronchopulmonary dysplasia (in revision).
Scheible K, Ryan R, Ahmed Q, D'Angelis C, Kumar V, Lakshinrishimha S, Metlay L, Nickerson P, Wang H, Huycke H, Rangel-Moreno J, Misra R, Pryhuber G.
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