Alissa Huston is a Rochester native who received her medical degree at the University of Buffalo, and went on to complete an Internal Medicine residency at Strong Memorial Hospital. She then attended the University of Pittsburgh for her Hematology/Oncology fellowship, during which time she was involved in research involving bone metastasis in cancer. Currently, she is an Associate Professor of Medicine at the Wilmot Cancer Institute at the University of Rochester, where her clinical efforts are focused on breast cancer. She is also the Co-Medical Director of the Pluta Integrative Oncology & Wellness Center. Her research efforts focus on understanding the effects of treatment for breast cancer upon bone health and how integrative modalities can help mitigate symptoms for cancer patients as they undergo treatment. She is a member of the American Society of Clinical Oncology and the Society for Integrative Oncology. Her philosophy is that there is no singular approach to patient care. Even though many patients may carry the same diagnosis, each individual is affected by that illness in a different way. Patients are not perceived as just a number, but instead approached and treated as the unique individuals they represent.

Faculty Appointments

Associate Professor - Department of Medicine, Hematology/Oncology (SMD)

Credentials

Residency & Fellowship

Fellowship, Hematology & Oncology, University of Pittsburgh School of Medicine. 2003 - 2006

Residency, Internal Medicine, University of Rochester Medical Center. 2001 - 2003

Internship, Internal Medicine, University of Rochester Medical Center. 2000 - 2001

Education

MD | SUNY at Buffalo-School of Medicine & Biomedical Sciences (USA). 2000

Awards

Jacob Gitelman Award. 2014

Lawrence A. Kohn Senior Teaching Fellowship Award. 2009 - 2011

ASH Clinical Research Training Institute (ASH-CRTI) Award. Phase I Trial of Perifosine and 17-DMAG in Patients with Relapsed/Ref. 2005

ASCO/AACR Workshop Methods in Clinical Cancer Research Award. A Phase II Study Evaluating the Effects of COX-2 Inhibition on Lev. 2005

Cancer Education Consortium Workshop Award: Clinical Pharmacology of Anticancer Agents. 2004

AMWA Janet M. Glasgow Memorial Achievement Citation. 2000

Induction into Alpha Omega Alpha Society. 1999

James A. Gibson Anatomical Society Award. 1997

Research

Clinical Trials

A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 as Adjuvant therapy for Triple Receptor-Negative Breast Cancer or Positive Lymph Nodes After Neoadjuvant Chemotherapy

Lead Researcher: Alissa Huston

The purpose of this study is to compare treated subjects' invasive disease-free survival of patients with triple-negative breast cancer after neoadjuvant chemotherapy.

Publications

Journal Articles

A whole food, plant-based randomized controlled trial in metastatic breast cancer: feasibility, nutrient, and patient-reported outcomes.

Campbell EK, Campbell TM, Culakova E, Blanchard L, Wixom N, Guido JJ, Fetten J, Huston A, Shayne M, Janelsins MC, Mustian KM, Moore RG, Peppone LJ

Breast cancer research and treatment.. 2024 July 206 (2):273-283. Epub 03/30/2024.

A whole-food, plant-based randomized controlled trial in metastatic breast cancer: weight, cardiometabolic, and hormonal outcomes.

Campbell TM, Campbell EK, Culakova E, Blanchard LM, Wixom N, Guido JJ, Fetten J, Huston A, Shayne M, Janelsins MC, Mustian KM, Moore RG, Peppone LJ

Breast cancer research and treatment.. 2024 June 205 (2):257-266. Epub 03/06/2024.

Establishing an Integrative Oncology Service: Essential Aspects of Program Development.

Lacey J, Huston A, Lopez G, Vozmediano JR, Lam CS, Narayanan S, Lu W, Wolf U, Subbiah IM, Richard P, Lopez AM, Rao S, Frenkel M

Current oncology reports.. 2024 March 26 (3):200-211. Epub 02/15/2024.

Editor's Note: Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment.

Huston A, Leleu X, Jia X, Moreau AS, Ngo HT, Runnels J, Anderson J, Alsayed Y, Roccaro A, Vallet S, Hatjiharissi E, Tai YT, Sportelli P, Munshi N, Richardson P, Hideshima T, Roodman DG, Anderson KC, Ghobrial IM

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2024 February 1630 (4):922. Epub 1900 01 01.

A Whole Food, Plant-Based Randomized Controlled Trial in Metastatic Breast Cancer: Feasibility, Nutrient, and Patient-Reported Outcomes.

Campbell , Campbell TM, Culakova E, Blanchard BLM, Wixom RBN, Guido MJ, Fetten J, Huston A, Shayne M, Janelsins M, Mustian PK, Moore RG, Peppone LJ

Research square.. 2023 November 21 Epub 11/21/2023.

A Whole-Food, Plant-Based Randomized Controlled Trial in Metastatic Breast Cancer: Weight, Cardiometabolic, and Hormonal Outcome.

Campbell TM, Campbell EK, Culakova E, Blanchard L, Wixom N, Guido J, Fetten J, Huston A, Shayne M, Janelsins MC, Mustian KM, Moore RG, Peppone LJ

Research square.. 2023 November 8 Epub 11/08/2023.

Integrative Oncology Care of Symptoms of Anxiety and Depression in Adults With Cancer: Society for Integrative Oncology-ASCO Guideline.

Carlson LE, Ismaila N, Addington EL, Asher GN, Atreya C, Balneaves LG, Bradt J, Fuller-Shavel N, Goodman J, Hoffman CJ, Huston A, Mehta A, Paller CJ, Richardson K, Seely D, Siwik CJ, Temel JS, Rowland JH

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2023 October 141 (28):4562-4591. Epub 08/15/2023.

Problem-solving skills training in adult cancer survivors: Bright IDEAS-AC pilot study.

Noyes K, Zapf AL, Depner RM, Flores T, Huston A, Rashid HH, McNeal D, Constine LS, Fleming FJ, Wilding GE, Sahler OJZ

Cancer treatment and research communications.. 2022 31 :100552. Epub 03/25/2022.

An Atypical Presentation of Hemophagocytic Lymphohistiocytosis (HLH) Secondary to Occult Hodgkin Lymphoma.

Komisarof J, McGann K, Huston A, Katerji H, Morgan MA

Case reports in hematology.. 2021 2021 :6672257. Epub 07/24/2021.

The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice.

Lei W, Duan R, Li J, Liu X, Huston A, Boyce BF, Yao Z

Scientific reports.. 2020 April 2410 (1):7004. Epub 04/24/2020.

Information and Emotional Support Needs of Families Whose Infant Was Diagnosed With SCID Through Newborn Screening.

Raspa M, Lynch M, Squiers L, Gwaltney A, Porter K, Peay H, Huston A, Fitzek B, Boyle JG

Frontiers in immunology.. 2020 11 :885. Epub 05/06/2020.

The Landscape of Severe Combined Immunodeficiency Newborn Screening in the United States in 2020: A Review of Screening Methodologies and Targets, Communication Pathways, and Long-Term Follow-Up Practices.

Sheller R, Ojodu J, Griffin E, Edelman S, Yusuf C, Pigg T, Huston A, Fitzek B, Boyle JG, Singh S

Frontiers in immunology.. 2020 11 :577853. Epub 10/28/2020.

The effects of high-dose calcitriol and individualized exercise on bone metabolism in breast cancer survivors on hormonal therapy: a phase II feasibility trial.

Peppone LJ, Ling M, Huston AJ, Reid ME, Janelsins MC, Puzas JE, Kamen C, Del Giglio A, Asare M, Peoples AR, Mustian KM

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.. 2018 August 26 (8):2675-2683. Epub 02/22/2018.

Associations between inflammatory markers and cognitive function in breast cancer patients receiving chemotherapy.

Williams AM, Shah R, Shayne M, Huston AJ, Krebs M, Murray N, Thompson BD, Doyle K, Korotkin J, van Wijngaarden E, Hyland S, Moynihan JA, Cory-Slechta DA, Janelsins MC

Journal of neuroimmunology.. 2018 January 15314 :17-23. Epub 10/18/2017.

Use of modified Magee equations and histologic criteria to predict the Oncotype DX recurrence score.

Turner BM, Skinner KA, Tang P, Jackson MC, Soukiazian N, Shayne M, Huston A, Ling M, Hicks DG

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2015 July 28 (7):921-31. Epub 05/01/2015.

Cost effectiveness analysis of genetic testing for breast and ovarian cancer susceptibility genes: BRCA1 and BRCA2.

Kaldate R, Huston A, McCoy H, Cardeiro D, Noyes K

The breast journal.. 2014 20 (3):325-6. Epub 04/08/2014.

Dedicated Breast CT: Feasibility for Monitoring Neoadjuvant Chemotherapy Treatment.

Vedantham S, O'Connell AM, Shi L, Karellas A, Huston AJ, Skinner KA

Journal of clinical imaging science.. 2014 4 :64. Epub 11/29/2014.

Axillary recurrence (AR) after negative sentinel node biopsy (SNB): Who is at risk?

Hicks DG, Tang P, Shayne M, Huston A, Ling MN, Skinner KA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2012 September 2030 (27_suppl):180. Epub 1900 01 01.

Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease.

D'Souza S, del Prete D, Jin S, Sun Q, Huston AJ, Kostov FE, Sammut B, Hong CS, Anderson JL, Patrene KD, Yu S, Velu CS, Xiao G, Grimes HL, Roodman GD, Galson DL

Blood.. 2011 December 22118 (26):6871-80. Epub 10/31/2011.

Few changes observed in polysomnographic-assessed sleep before and after completion of chemotherapy.

Roscoe JA, Perlis ML, Pigeon WR, O'Neill KH, Heckler CE, Matteson-Rusby SE, Palesh OG, Shayne M, Huston A

Journal of psychosomatic research.. 2011 December 71 (6):423-8. Epub 09/22/2011.

The effect of various vitamin D supplementation regimens in breast cancer patients.

Peppone LJ, Huston AJ, Reid ME, Rosier RN, Zakharia Y, Trump DL, Mustian KM, Janelsins MC, Purnell JQ, Morrow GR

Breast cancer research and treatment.. 2011 May 127 (1):171-7. Epub 03/08/2011.

An exploratory study on the effects of an expectancy manipulation on chemotherapy-related nausea.

Roscoe JA, O'Neill M, Jean-Pierre P, Heckler CE, Kaptchuk TJ, Bushunow P, Shayne M, Huston A, Qazi R, Smith B

Journal of pain and symptom management.. 2010 September 40 (3):379-90. Epub 06/25/2010.

The efficacy of calcitriol therapy in the management of bone loss and fractures: a qualitative review.

Peppone LJ, Hebl S, Purnell JQ, Reid ME, Rosier RN, Mustian KM, Palesh OG, Huston AJ, Ling MN, Morrow GR

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.. 2010 July 21 (7):1133-49. Epub 12/04/2009.

Cost-effectiveness of testing for breast cancer susceptibility genes.

Holland ML, Huston A, Noyes K

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.. 2009 12 (2):207-16. Epub 07/18/2008.

Involvement of hepcidin in the anemia of multiple myeloma.

Sharma S, Nemeth E, Chen YH, Goodnough J, Huston A, Roodman GD, Ganz T, Lichtenstein A

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2008 June 114 (11):3262-7. Epub 1900 01 01.

Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment.

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2008 February 114 (3):865-74. Epub 1900 01 01.

Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.

Francis LK, Alsayed Y, Leleu X, Jia X, Singha UK, Anderson J, Timm M, Ngo H, Lu G, Huston A, Ehrlich LA, Dimmock E, Lentzsch S, Hideshima T, Roodman GD, Anderson KC, Ghobrial IM

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2006 November 1512 (22):6826-35. Epub 1900 01 01.

Role of the microenvironment in multiple myeloma bone disease.

Huston A, Roodman GD

Future oncology.. 2006 June 2 (3):371-8. Epub 1900 01 01.

Books

Translational Therapeutic Strategies in Multiple Myeloma (2007)

Chapter: Myeloma Bone Disease

Authors: A. Huston and G. D. Roodman

Publisher: Informa Healthcare, Inc. 2007

Cancer Supportive Care: Advances in Therapeutic Strategies (2007)

Chapter: Skeletal Complications: Bone Metabolism and Novel Targeted Agents

Authors: A. Huston

Publisher: Informa healthcare, Inc. 2007

Ratings & Comments

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Ratings

During this visit, did this provider spend enough time with you?

4.9

During this visit, did this provider show respect for what you had to say?

4.9

During this visit did this provider give you easy to understand information about these health questions or concerns?

4.9

During this visit, did this provider listen carefully to you?

4.9

During this visit, did this provider explain things in a way that was easy to understand?

4.9

Patient Comments

She is wonderful Dr. Huston

Jul 31, 2024

I always feel cared and protected as well as informed

Jul 20, 2024

5.0

Appears to be guiding me to the standard treatment. We'll see what happens.

Jun 19, 2024

5.0

[...] I hope I never have to refer a friend for cancer care, but if I sadly do I would definitely recommend Dr. Huston.

May 13, 2024

5.0

Dr. Huston always treats me like I am the only patient she has. She answers all of my questions and listens to my concerns. She has been my oncologist for over 9 years and I trust her to always make good decisions for my treatment plan.

Apr 15, 2024

Dr Huston is very detail and you can tell she really cares by the way she handles herself. She is saving my life.

Mar 01, 2024

5.0

Love Dr. Huston!

Dec 29, 2023

5.0

Amazing care given. Doctor even completed my medical connection.

Oct 19, 2023

5.0

Dr Huston made me feel confident

Mar 25, 2023

5.0

Dr Huston was very informative, compassionate and explained my diagnosis in terms that were helpful to understand

Mar 22, 2023

5.0

This was an exploratory and information gathering session for me and it met my high expectations.

Mar 22, 2023

The visit with Dr. Huston was extremely helpful, she listened to my concerns, asked questions, provided answers to my questions and worked with me to determine the best plan of care.

Mar 07, 2023

5.0

Dr. Huston is THE BEST!

Feb 16, 2023

Extremely satisfied with my doctor

Jan 21, 2023

5.0

Dr. Huston was great. [...]

Dec 27, 2022

5.0

The dr reached out to me after 5pm to give me an update which was very nice.

Oct 29, 2022

5.0

Dr Huston was excellent

Oct 20, 2022

5.0

She was thorough and had reviewed my chart and had clarifying questions about my history and treatment. She seems very forward thinking interms of future treatments and I was happy with how she listened and tge tine she spent.

Sep 26, 2022

5.0

Great!

Sep 20, 2022

5.0

Dr Huston listens & gives well-informed guidance. She is upbeat and has a great, encouraging tone.

Jun 25, 2022

5.0

Dr. Huston and her team are great!!!!

Jun 05, 2022

5.0

Dr Huston was very caring and professional. She thoroughly reviewed my current health issues and medical history. We had a complete discussion of treatment options and next steps. She also made me aware of several resources to help support my treatment plan such as massage, acupuncture, nutrition consult,yoga etc

May 21, 2022

5.0

Dr. Huston is absolutely amazing! As busy as a provider she is, she NEVER rushes you or makes you feel rushed. Beyond grateful for the care she provides.

Apr 11, 2022

I felt the sincerity and care of Dr. Huston

Apr 09, 2022

5.0

Continually provide excellent follow up for any extraordinary issues along with providing additional specialty providers in a timely manner.

Mar 28, 2022

5.0

Dr. Huston is caring, and thorough, and a great listener.

Mar 26, 2022