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Bruce I. Goldman, M.D.

Bruce I. Goldman, M.D.

UR Medicine Labs

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UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
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Contact

Office (585) 275-8181
Fax (585) 273-1027
Administrative (585) 275-3202

About Me

Dr. Goldman is Director of Renal Pathology and the Electron Microscopy Laboratory and lead pathologist for the cardiac transplant service.
Dr. Goldman is Director of Renal Pathology and the Electron Microscopy Laboratory and lead pathologist for the cardiac transplant service.

Certified Specialties

Pathology, Anatomic Pathology & Clinical Pathology - American Board of Pathology

Faculty Appointments

Professor (Part-Time) - Department of Pathology and Laboratory Medicine (SMD)

Credentials

Residency & Fellowship

Residency, Pathology, Anatomic Pathology & Clinical Pathology, Mount Sinai Hospital. 1981 - 1984

Internship, Pathology, Anatomic Pathology & Clinical Pathology, Mount Sinai Hospital. 1980 - 1981

Education

MD | Northwestern University Feinberg School of Medicine. 1980

Awards

University Teaching Academy Temple University 2004

Academy of Distinguished Educators in Medicine,Temple University ,Schl of Med 2004

Golden Apple Award Temple University Schl of Med. 2003

Lindback Award for Temple University
Distinguished Teaching 2002

Golden Apple Award Temple University Schl of Med 2001

Golden Apple Award Temple University Schl of Med 1998

Alpha Omega Alpha Northwestern U Med Schl 1977

Winton Award in Northwestern U Med Schl
Biochemistry 1977

Phi Beta Kappa Univ. of IL 1974

Research

Most recently, Dr. Goldman completed a study of the resuscitation and transplantation of non-beating donor hearts for the American Heart Association. He is working with Dr. C. Platsoucas in investigating the role of T cell receptor expression in Systemic Sclerosis. They have also studied the role of...
Most recently, Dr. Goldman completed a study of the resuscitation and transplantation of non-beating donor hearts for the American Heart Association. He is working with Dr. C. Platsoucas in investigating the role of T cell receptor expression in Systemic Sclerosis. They have also studied the role of T cells in Abdominal aortic aneurysm, an antigen driven autoimmune disease, and the immunopathogenesis of chronic cardiac graft rejection. Dr. Goldman's AHA grants have involved the growth and proliferation of human fetal cardiac myocytes, and the role of Insulin-like Growth Factor I in human cardiac cells.

Publications

Journal Articles

Caseous Calcification of the Mitral Annulus: Calcified Toothpaste of the Heart.

Jorgenson KM, McMullen PD, Goldman BI, Jacob-Leonce M

The American journal of forensic medicine and pathology.. 2025 March 146 (1):59-63. Epub 07/18/2024.

Error codes at autopsy to study potential biases in diagnostic error.

Goldman BI, Bharadraj R, Fuller M, Love T, Metlay L, Dignan C

Diagnosis.. 2023 November 110 (4):375-382. Epub 10/05/2023.

The Clinicopathologic Spectrum of Membranous Nephropathy with Lupus-Like Features.

Choung HYG, Moore C, Le TH, Guirguis P, McKeown JM, Jean-Gilles J, Goldman B

Nephron.. 2023 147 (7):424-433. Epub 02/06/2023.

The spectrum of renal diseases with lupus-like features: a single-center study.

Ahmed M, Love T, Moore C, Le TH, Jean-Gilles J, Goldman B, Choung HYG

Renal failure.. 2022 December 44 (1):581-593. Epub 1900 01 01.

Light chain deposition disease masquerading as smoking-associated nodular glomerulosclerosis with deposits identified by electron microscopy only.

Alom MS, Grewal R, Passero FC, Goldman B, Choung HYG

CEN case reports.. 2022 November 11 (4):448-452. Epub 03/22/2022.

Small Molecule Inhibitors of Nuclear Export and the Amelioration of Lupus by Modulation of Plasma Cell Generation and Survival.

Rangel-Moreno J, Garcia-Hernandez ML, Owen T, Barnard J, Becerril-Villanueva E, Kashyap T, Argueta C, Gamboa-Dominguez A, Tamir S, Landesman Y, Goldman BI, Ritchlin CT, Anolik JH

Arthritis & rheumatology.. 2022 August 74 (8):1363-1375. Epub 06/28/2022.

Subepithelial deposits with microspherular structures in membranous glomerulonephritis.

Choung HYG, Jean-Gilles J, Goldman B

Ultrastructural pathology.. 2022 July 446 (4):377-387. Epub 06/16/2022.

Myeloid bodies is not an uncommon ultrastructural finding.

Choung HYG, Jean-Gilles J, Goldman B

Ultrastructural pathology.. 2022 January 246 (1):130-138. Epub 02/01/2022.

A rare case of diffuse crescents in fibrillary glomerulonephritis?.

Choung HYG, Grewal R, Goldman B

Clinical nephrology.. 2022 January 97 (1):53-56. Epub 1900 01 01.

The spectrum of macrophage-predominant inflammatory myocardial disease presenting as fulminant heart failure.

Goldman BI, Choung HY, Sainvil M, Miller CW

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.. 2022 57 :107393. Epub 10/23/2021.

Prednisone-induced sustained remission in a patient with familial fibronectin glomerulopathy (GFND).

Goldman BI, Panner BJ, Welle SL, Gross MD, Gray DA

CEN case reports.. 2021 November 10 (4):510-514. Epub 04/10/2021.

Segmental membranous nephropathy.

Choung HYG, Goldman B

Clinical and experimental nephrology.. 2021 July 25 (7):700-707. Epub 03/23/2021.

Segmental membranous nephropathy

Choung, H. Y. G.; Goldman, B.

Clin Exp Nephrol. 2021; 25(7): 700-707.

Potassium conservation is impaired in mice with reduced renal expression of Kir4.1.

Malik S, Lambert E, Zhang J, Wang T, Clark HL, Cypress M, Goldman BI, Porter GA, Pena S, Nino W, Gray DA

American journal of physiology. Renal physiology.. 2018 November 1315 (5):F1271-F1282. Epub 08/15/2018.

Conduction Dysfunction and Near Expunction: Giant Cell Myocarditis.

Gleber C, Yoruk A, Eastburg L, Goldman BI, Cameron SJ

The American journal of medicine.. 2018 November 131 (11):1317-1320. Epub 05/03/2018.

Neutrophils Slow Disease Progression in Murine Lupus via Modulation of Autoreactive Germinal Centers.

Bird AK, Chang M, Barnard J, Goldman BI, Meednu N, Rangel-Moreno J, Anolik JH

The Journal of immunology : official journal of the American Association of Immunologists.. 2017 July 15199 (2):458-466. Epub 06/05/2017.

Green Inclusions in Neutrophils and Monocytes Are an Indicator of Acute Liver Injury and High Mortality.

Patel N, Hoffman CM, Goldman BI, Bentley K, Burack WR, Evans AG

Acta haematologica.. 2017 138 (2):85-90. Epub 08/17/2017.

Inhibition of G Protein ?? Subunit Signaling Abrogates Nephritis in Lupus-Prone Mice.

Rangel-Moreno J, To JY, Owen T, Goldman BI, Smrcka AV, Anolik JH

Arthritis & rheumatology.. 2016 September 68 (9):2244-56. Epub 1900 01 01.

Reviving the Hospital Autopsy.

Goldman BI

Archives of pathology & laboratory medicine.. 2016 June 140 (6):503-4. Epub 1900 01 01.

Beneficial effect of novel proteasome inhibitors in murine lupus via dual inhibition of type I interferon and autoantibody-secreting cells.

Ichikawa HT, Conley T, Muchamuel T, Jiang J, Lee S, Owen T, Barnard J, Nevarez S, Goldman BI, Kirk CJ, Looney RJ, Anolik JH

Arthritis and rheumatism.. 2012 February 64 (2):493-503. Epub 1900 01 01.

Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus.

Bekar KW, Owen T, Dunn R, Ichikawa T, Wang W, Wang R, Barnard J, Brady S, Nevarez S, Goldman BI, Kehry M, Anolik JH

Arthritis and rheumatism.. 2010 August 62 (8):2443-57. Epub 1900 01 01.

Unusual features of malignant pleural mesothelioma metastatic to the mediastinal lymph nodes.

Wagner D, Bourne PA, Yang Q, Goldman BI, Lewis JS, Xu H

Applied immunohistochemistry & molecular morphology : AIMM. 2008 May 16 (3):301-7. Epub 1900 01 01.

Long-term intermittent compression increases arteriographic collaterals in a rabbit model of femoral artery occlusion.

van Bemmelen PS, Choudry RG, Salvatore MD, Goldenberg M, Goldman BI, Blebea J

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.. 2007 September 34 (3):340-6. Epub 06/19/2007.

Lethal vertebral artery dissection in pregnancy: a case report and review of the literature.

Tuluc M, Brown D, Goldman B

Archives of pathology & laboratory medicine.. 2006 April 130 (4):533-5. Epub 1900 01 01.

Human myocardial cell lines generated with SV40 temperature-sensitive mutant tsA58.

Goldman BI, Amin KM, Kubo H, Singhal A, Wurzel J

In vitro cellular & developmental biology. Animal.. 2006 42 (10):324-31. Epub 1900 01 01.

Regionally heterogeneous tissue mechanics in cardiac amyloidosis.

Petre RE, Quaile MP, Wendt K, Houser SR, Wald J, Goldman BI, Margulies KB

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.. 2005 December 12 (4):246-50. Epub 1900 01 01.

Potential suitability for transplantation of hearts from human non-heart-beating donors: data review from the Gift of Life Donor Program.

Singhal AK, Abrams JD, Mohara J, Hasz RD, Nathan HM, Fisher CA, Furukawa S, Goldman BI

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.. 2005 October 24 (10):1657-64. Epub 1900 01 01.

Singhal AK, Abrams JD, Mohara J, Hasz RD, Nathan HM, Fisher CA, Furukawa S, Goldman BI.

Potential suitability for transplantation of hearts from human

Effects of nutrient and hemoglobin enriched cell free perfusates upon ex vivo isolated rat heart preparation.

Mohara J, Aguilera I, Goldman BI, Fisher CA, Gaughan JP, Libonati JR, Furukawa S, Singhal AK

ASAIO journal : a peer-reviewed journal of the American Society for Artificial Internal Organs.. 2005 51 (3):288-95. Epub 1900 01 01.

Effect of older donor age on risk for mortality after heart transplantation.

Gupta D, Piacentino V, Macha M, Singhal AK, Gaughan JP, McClurken JB, Goldman BI, Fisher CA, Beltramo D, Monacchio J, Eisen HJ, Furukawa S

The Annals of thoracic surgery.. 2004 September 78 (3):890-9. Epub 1900 01 01.

Premature coronary disease in systemic lupus.

Wurzel J, Goldman BI

The New England journal of medicine.. 2004 April 8350 (15):1571-5; author reply 1571-5. Epub 1900 01 01.

Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus.

Roman MJ, Shanker BA, Davis A, Lockshin MD, Sammaritano L, Simantov R, Crow MK, Schwartz JE, Paget SA, Devereux RB, Salmon JE

The New England journal of medicine.. 2003 December 18349 (25):2399-406. Epub 1900 01 01.

Pharmacologic pre-conditioning and controlled reperfusion prevent ischemia-reperfusion injury after 30 minutes of hypoxia/ischemia in porcine hearts.

Fedalen PA, Piacentino V, Jeevanandam V, Fisher C, Greene J, Margulies KB, Houser SR, Furukawa S, Singhal AK, Goldman BI

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.. 2003 November 22 (11):1234-44. Epub 1900 01 01.

Reduction of atherosclerosis in low-density lipoprotein receptor-deficient mice by passive administration of antiphospholipid antibody.

Nicolo D, Goldman BI, Monestier M

Arthritis and rheumatism.. 2003 October 48 (10):2974-8. Epub 1900 01 01.

Identical alpha-chain T-cell receptor transcripts are present on T cells infiltrating coronary arteries of human cardiac allografts with chronic rejection.

Xu B, Sakkas LI, Goldman BI, Jeevanandam V, Gaughan J, Oleszak EL, Platsoucas CD

Cellular immunology.. 2003 October 225 (2):75-90. Epub 1900 01 01.

Early and late results of left ventricular reshaping by passive cardiac-support device in canine heart failure.

Kashem A, Kashem S, Santamore WP, Crabbe DL, Margulies KB, Melvin DB, Goldman BI

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.. 2003 September 22 (9):1046-53. Epub 1900 01 01.

Reduction of atherosclerosis in low-density lipoprotein receptor-deficient mice by passive administration of antiphospholipid antibody.

Nicolo D, Goldman BI, Monestier M.

Arthritis Rheum. 2003; 48(10): 4-8.

CardioClasp changes left ventricular shape acutely in enlarged canine heart.

Kashem A, Santamore WP, Hassan S, Melvin DB, Crabbe DL, Margulies KB, Goldman BI, Llort F, Krieger C, Lesniak J.

J Card Surg. 2003 Jul-Aug;18 Suppl 2:S49-60. 2003; 18(Suppl. 2): S49-60.

Prevention of ischemia-reperfusion injury in non-beating porcine hearts with pharmacological preconditioning and controlled reperfusion

Fedalen PA, Fisher C, Furukawa S, Houser S, Jeevanandam V, Margulies K, Piacentino III V, Goldman B.

J Heart Lung Transpl. 2003; 22: 1234-1244.

Cardiac transplantation across a positive prospective lymphocyte cross-match in sensitized recipients.

Leech SH, Rubin S, Eisen HJ, Mather PJ, Goldman BI, McClurken JB, Furukawa S

Clinical transplantation.. 2003 17 Suppl 9 :17-26. Epub 1900 01 01.

CardioClasp changes left ventricular shape acutely in enlarged canine heart.

Kashem A, Santamore WP, Hassan S, Melvin DB, Crabbe DL, Margulies KB, Goldman BI, Llort F, Krieger C, Lesniak J

Journal of cardiac surgery.. 2003 18 Suppl 2 :S49-60. Epub 1900 01 01.

Allograft inflammatory factor-1 expression correlates with cardiac rejection and development of cardiac allograft vasculopathy.

Autieri MV, Kelemen S, Thomas BA, Feller ED, Goldman BI, Eisen HJ

Circulation.. 2002 October 22106 (17):2218-23. Epub 1900 01 01.

L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices.

Chen X, Piacentino V, Furukawa S, Goldman B, Margulies KB, Houser SR

Circulation research.. 2002 September 2091 (6):517-24. Epub 1900 01 01.

Allograft inflammatory factor-1 expression correlates with cardiac rejection and development of cardiac allograft vasculopathy.

Circulation. 2002 Oct 22;106(17):2218-23. 2002; 106(17): 2218-23.

Evidence that human cardiac myocytes divide after myocardial infarction.

Goldman BI, Wurzel J

The New England journal of medicine.. 2001 October 11345 (15):1131. Epub 1900 01 01.

Hematopoiesis/erythropoiesis in myocardial infarcts.

Goldman BI, Wurzel J

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2001 June 14 (6):589-94. Epub 1900 01 01.

Apoptosis in chronic rejection of human cardiac allografts.

Xu B, Sakkas LI, Slachta CA, Goldman BI, Jeevanandam V, Oleszak EL, Platsoucas CD

Transplantation.. 2001 April 2771 (8):1137-46. Epub 1900 01 01.

Coronary arteries with chronic rejection contain oligoclonal T cells: persistence of clonally expanded T cell receptor transcripts from the early posttransplantation period through chronic rejection.

Slachta CA, Jeevanandam V, Goldman B, Lin WL, Platsoucas CD

Transplantation proceedings.. 2001 33 (1-2):452-5. Epub 1900 01 01.

Gamma-chain T-cell receptor transcripts are clonally expanded in the coronary arteries of cardiac allografts from patients with chronic rejection.

Jung W, Lu S, Qin P, Afolabi A, Slachta C, Jeevanandam V, Goldman B, Platsoucas CD

Transplantation proceedings.. 2001 33 (1-2):456-8. Epub 1900 01 01.

Coronary arteries from human cardiac allografts with chronic rejection contain oligoclonal T cells: persistence of identical clonally expanded TCR transcripts from the early post-transplantation period (endomyocardial biopsies) to chronic rejection (coronary arteries).

Slachta CA, Jeevanandam V, Goldman B, Lin WL, Platsoucas CD

The Journal of immunology : official journal of the American Association of Immunologists.. 2000 September 15165 (6):3469-83. Epub 1900 01 01.

Angiogenesis factors in acute myocardial ischemia and infarction.

Wurzel J, Goldman BI

The New England journal of medicine.. 2000 July 13343 (2):148-9. Epub 1900 01 01.

EC3, a heterodimeric disintegrin from Echis carinatus, inhibits human and murine alpha4 integrin and attenuates lymphocyte infiltration of Langerhans islets in pancreas and salivary glands in nonobese diabetic mice.

Brando C, Marcinkiewicz C, Goldman B, McLane MA, Niewiarowski S

Biochemical and biophysical research communications.. 2000 January 7267 (1):413-7. Epub 1900 01 01.

T cells infiltrating coronary arteries of cardiac allografts with chronic rejection contain clonally expanded T lymphocytes.

Slachta CA, Jeevanandam V, Goldman B, Platsoucas CD

Transplantation proceedings.. 1998 June 30 (4):1002-4. Epub 1900 01 01.

Altered myocardial phenotype after mechanical support in human beings with advanced cardiomyopathy.

Altemose GT, Gritsus V, Jeevanandam V, Goldman B, Margulies KB

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.. 1997 July 16 (7):765-73. Epub 1900 01 01.

Differential expression of c-jun and jun-D in end-stage human cardiomyopathy

Pollack PS, Pasquarello LM, Budjak R, Fernandez E, Soprano KJ, Redfern BJ, Goldman B.

J Cellular Biochem. 1997; 65(2): 245-253.

Expression of very low density lipoprotein receptor in the vascular wall. Analysis of human tissues by in situ hybridization and immunohistochemistry.

Multhaupt HA, Gåfvels ME, Kariko K, Jin H, Arenas-Elliot C, Goldman BI, Strauss JF, Angelin B, Warhol MJ, McCrae KR

The American journal of pathology.. 1996 June 148 (6):1985-97. Epub 1900 01 01.

Expression of VLDL receptor in the vascular wall: analysis of human tissues by in situ hybridization and immunohistochemistry

Hanks AB, Gafvels ME, Kariko K, Jin H, Arenas-Elliott C, Goldman BI, Strauss J, Angelin B, Warhol M, McCrae K.

Am J Pathol. 1996; 148(188-197).

Epidermal growth factor promotes a cardiomyoblastic phenotype in human fetal cardiac myocytes

Goldman B, Mach A, Wurzel J.

Exp Cell Res. 1996; 238: 237-245.

Consistencies and controversies in the application of teh ISHLT working formulation for heart transplant biopsy specimens

Winter GL, McManus BM et al (for the Rapamycin Cardiac Rejection Treatment Trial Pathologists) (B Goldman/Temple University included among 17 collaborating pathologists at 16 participating transplant centers).

J Heart Lung Transpl. 1996; 15: 728-735.

Human fetal cardiocytes in enriched culture.

Goldman BI, Wurzel J

In vitro cellular & developmental biology. Animal.. 1995 November 31 (10):731-4. Epub 1900 01 01.

C-myc expression in the pressure overloaded feline ventricle

Pollack PS, Houser SR, Hillerman S, Bujak R, Goldman B.

J Cellular Biochem. 1994; 54: 78-84.

Post-partum multi-vessel coronary dissection

Mather PJ, Hansen CL, Goldman BI, Pina I, Jeevanandam V, Bove AA.

J Heart Lung Transpl. 1994; 13: 533-537.

Popliteal venous aneurysm: report of two cases and review of the world literature.

Aldridge SC, Comerota AJ, Katz ML, Wolk JH, Goldman BI, White JV

Journal of vascular surgery.. 1993 October 18 (4):708-15. Epub 1900 01 01.

Aortic dissection in cardiac allograft recipients

Coppola D, Alpern J, Brozena S, Goldman B.

Arch Pathol Lab Med. 1993; 117: 11-14.

Effects of subcultivation and culture medium on differentiation of human fetal cardiac myocytes.

Goldman BI, Wurzel J

In vitro cellular & developmental biology : journal of the Tissue Culture Association.. 1992 February 28A (2):109-19. Epub 1900 01 01.

Growth and partial differentiation of presumptive human cardiac myoblasts in culture.

Kohtz DS, Dische NR, Inagami T, Goldman B

The Journal of cell biology.. 1989 March 108 (3):1067-78. Epub 1900 01 01.

Pathology of aortic valvuloplasty: findings after postmortem, successful, and failed dilatations.

Berdoff R, Strain J, Crandall C, Ghali V, Goldman B.

Am Heart Jour. 1989; 117: 688-690.

Atherosclerotic plaque at the carotid artery bifurcation. Correlation of ultrasonographic imaging with morphology.

Weinberger J, Marks SJ, Gaul JJ, Goldman B, Schanzer H, Jacobson J, Dikman S

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.. 1987 July 6 (7):363-6. Epub 1900 01 01.

Influence of pressure on permeability of normal and diseased muscular arteries to horseradish peroxidase. A new catheter approach.

Goldman B, Blanke H, Wolinsky H

Atherosclerosis.. 1987 June 65 (3):215-25. Epub 1900 01 01.

Glandular cardiac myxomas. Histologic, immunohistochemical, and ultrastructural evidence of epithelial differentiation.

Goldman BI, Frydman C, Harpaz N, Ryan SF, Loiterman D

Cancer.. 1987 May 1559 (10):1767-75. Epub 1900 01 01.

Restrictive type hemodynamics following valve surgery for rheumatic heart disease.

Sherman W, Lazar E, Goldman B, AMbrose J.

Internl J Cardiol. 1987; 17: 257-266.

Sudden hemodynamic collapse following cardiac tamponade

Coplan N, Goldman B, Mechanic G, Mazzucchi F, Halperin J.

Am Heart J. 1986; 111(2).

Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid.

Carone FA, Nakamura S, Goldman B

Laboratory investigation; a journal of technical methods and pathology.. 1985 June 52 (6):605-10. Epub 1900 01 01.

Books

Growth Factors and the Cardiovascular System (1993)

Chapter: Effects of growth factors on human cardiac myocytes

Heart Transplantation in Children (1990)

Chapter: Monitoring and treatment of rejection

Cellular and Molecular Biology of Muscle Development (1989)

Chapter: Induction of ANF expression is an early event marking the differentiation of human cardiac myoblasts in culture

Ratings & Comments

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