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John T. Horan, M.D., M.P.H.

John T. Horan, M.D., M.P.H.

Pediatrics

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UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
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Contact

Appointment (585) 275-2981

About Me

Dr. Horan earned a BA in psychology from Colgate University, an MD from Rutgers New Jersey Medical School and a Masters in Public Health with a concentration in clinical investigation from the University of Rochester. He completed his Pediatrics residency at the University of Rochester and his fell...
Dr. Horan earned a BA in psychology from Colgate University, an MD from Rutgers New Jersey Medical School and a Masters in Public Health with a concentration in clinical investigation from the University of Rochester. He completed his Pediatrics residency at the University of Rochester and his fellowship training in Pediatric hematology-oncology at Children’s National Health Center and the University of Rochester. He completed his fellowship training in Blood and Marrow Transplantation at the University of Rochester.
Dr. Horan joined the URMC Golisano Children’s Hospital Pediatric Hematology-Oncology team in February 2023, where he also held his first faculty appointment.

In his clinics he evaluates patients for blood and marrow transplantation for leukemia, sickle cell disease, bone marrow failure syndromes and other serious diseases and provides post-transplant care. He also follows patients with anemias, bleeding problems and other blood disorders.

Dr. Horan is active nationally in the Sickle Cell Transplant Advocacy and Research Alliance (STAR), an organization he helped found, and the Children’s Oncology Group. He is committed to improving outcomes in blood and marrow transplantation for acute myeloid leukemia, sickle cell disease and bone marrow failure disorders. He leads and helps lead a number of multicenter trials in these areas.

Prior to returning to URMC Golisano Children’s Hospital, he was part of the pediatric hematology-oncology programs at Children’s Healthcare of Atlanta/Emory University, Columbia University Medical Center and Boston Children’s Hospital/Dana-Farber Cancer Institute.

His clinical interests include:

Acute Myeloid Leukemia in children, adolescents and young adults
Mixed Phenotype acute leukemia
Blood and Marrow Transplant and Gene Therapy for Sickle Cell Disease
Bone marrow failure disorders
General Hematology

Certified Specialties

Pediatric Hematology-Oncology - American Board of Pediatrics

Pediatrics - American Board of Pediatrics

Faculty Appointments

Professor - Department of Pediatrics, Hematology and Oncology (SMD)

Credentials

Residency & Fellowship

Fellowship, Pediatric Hematology-Oncology, University of Rochester Medical Center. 1998 - 2000

Fellowship, Pediatric Hematology-Oncology, Children's National Medical Center. 1997 - 1998

Fellowship, Stem Cell Transplant, University of Rochester Medical Center. 1996 - 1997

Residency, Pediatrics, University of Rochester Medical Center. 1993 - 1996

Education

MSPH | University of Rochester School of Medicine/Dentistry (USA). 2003

MD | New Jersey Medical School. 1993

Publications

Journal Articles

Overlap chronic GVHD is associated with adverse survival outcomes compared to classic chronic GVHD.

Gorfinkel L, Raghunandan S, Watkins B, Hebert K, Neuberg DS, Bratrude B, Betz K, Yu A, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Blazar BR, Horan JT, Langston A, Kean LS, Qayed M

Bone marrow transplantation.. 2024 May 59 (5):680-687. Epub 02/21/2024.

Abatacept for the prevention of graft versus host disease in pediatric patients receiving 7/8 HLA-mismatched unrelated transplant for hematologic malignancies: a real-world analysis.

Raghunandan S, Gorfinkel L, Bratrude B, Suessmuth Y, Hebert K, Neuberg D, Williams KM, Schoettler ML, Langston AA, Kean LS, Qayed M, Horan J, Watkins BK

Bone marrow transplantation.. 2023 November 58 (11):1260-1263. Epub 08/14/2023.

Abatacept for graft versus host disease prophylaxis in patients 60 years and older receiving mismatched unrelated donor transplantation for hematologic malignancies.

Raghunandan S, Qayed M, Watkins BK, Graiser M, Gorfinkel L, Westbrook A, Gillespie S, Bratrude B, Petrovic A, Suessmuth Y, Horan J, Kean LS, Langston AA

Bone marrow transplantation.. 2023 November 58 (11):1264-1266. Epub 08/14/2023.

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events.

Takahashi T, Al-Kofahi M, Jaber M, Bratrude B, Betz KM, Suessmuth Y, Yu A, Neuberg DS, Choi SW, Davis JH, Duncan C, Giller RH, Grimley M, Harris AC, Jacobsohn DA, Lalefar NR, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Blazar BR, Horan JT, Watkins B, Langston A, Qayed M, Kean LS

Blood.. 2023 August 24142 (8):700-710. Epub 1900 01 01.

Abatacept for the prevention of GVHD in patients receiving mismatched unrelated transplants: a real-world analysis.

Raghunandan S, Gorfinkel L, Graiser M, Bratrude B, Suessmuth Y, Gillespie S, Westbrook AL, Williams KM, Schoettler ML, Kean LS, Horan JT, Langston AA, Qayed M, Watkins B

Blood advances.. 2023 August 227 (16):4395-4399. Epub 1900 01 01.

Abatacept GVHD prophylaxis in unrelated hematopoietic cell transplantation for pediatric bone marrow failure.

Stenger EO, Watkins B, Rogowski K, Chiang KY, Haight A, Leung K, Qayed M, Raghunandan S, Suessmuth Y, Kean L, Horan J

Blood advances.. 2023 May 237 (10):2196-2205. Epub 1900 01 01.

Long-Term Organ Function After HCT for SCD: A Report From the Sickle Cell Transplant Advocacy and Research Alliance.

Stenger E, Xiang Y, Wetzel M, Gillespie S, Chellapandian D, Shah R, Arnold SD, Bhatia M, Chaudhury S, Eckrich MJ, Kanter J, Kasow KA, Krajewski J, Nickel RS, Ngwube AI, Olson TS, Rangarajan HG, Wobma H, Guilcher GMT, Horan JT, Krishnamurti L, Shenoy S, Abraham A

Transplantation and cellular therapy.. 2023 January 29 (1):47.e1-47.e10. Epub 10/20/2022.

Hematopoietic Cell Transplantation in the Treatment of Pediatric Acute Myelogenous Leukemia and Myelodysplastic Syndromes: Guidelines from the American Society of Transplantation and Cellular Therapy.

Tarlock K, Sulis ML, Chewning JH, Pollard JA, Cooper T, Gamis A, Shenoy S, Kutny M, Horan J, Meshinchi S, Boelens JJ, Bleakley M, Carpenter PA, Kolb EA

Transplantation and cellular therapy.. 2022 September 28 (9):530-545. Epub 06/16/2022.

Abatacept for GVHD prophylaxis can reduce racial disparities by abrogating the impact of mismatching in unrelated donor stem cell transplantation.

Qayed M, Watkins B, Gillespie S, Bratrude B, Betz K, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Norkin M, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Waller EK, Langston A, Kean LS, Horan JT

Blood advances.. 2022 February 86 (3):746-749. Epub 1900 01 01.

Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD.

Watkins B, Qayed M, McCracken C, Bratrude B, Betz K, Suessmuth Y, Yu A, Sinclair S, Furlan S, Bosinger S, Tkachev V, Rhodes J, Tumlin AG, Narayan A, Cribbin K, Gillespie S, Gooley TA, Pasquini MC, Hebert K, Kapoor U, Rogatko A, Tighiouart M, Kim S, Bresee C, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Norkin M, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Waller EK, Levine JE, Ferrara JL, Blazar BR, Langston A, Horan JT, Kean LS

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2021 June 1039 (17):1865-1877. Epub 01/15/2021.

Hematopoietic stem cell transplant referral patterns for children with sickle cell disease vary among pediatric hematologist/oncologists' practice focus: A Sickle Cell Transplant Advocacy and Research Alliance (STAR) study.

Meier ER, Abraham AA, Ngwube A, Janson IA, Guilcher GMT, Horan J, Kasow KA

Pediatric blood & cancer.. 2021 March 68 (3):e28861. Epub 01/06/2021.

Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8 T cells drive gastrointestinal acute graft-versus-host disease.

Tkachev V, Kaminski J, Potter EL, Furlan SN, Yu A, Hunt DJ, McGuckin C, Zheng H, Colonna L, Gerdemann U, Carlson J, Hoffman M, Olvera J, English C, Baldessari A, Panoskaltsis-Mortari A, Watkins B, Qayed M, Suessmuth Y, Betz K, Bratrude B, Langston A, Horan JT, Ordovas-Montanes J, Shalek AK, Blazar BR, Roederer M, Kean LS

Science translational medicine.. 2021 January 1313 (576)Epub 1900 01 01.

Human leukocyte antigen (HLA) class I antibodies and transfusion support in paediatric HLA-matched haematopoietic cell transplant for sickle cell disease.

Nickel RS, Horan JT, Abraham A, Qayed M, Haight A, Ngwube A, Liang H, Luban NLC, Hendrickson JE

British journal of haematology.. 2020 April 189 (1):162-170. Epub 11/01/2019.

Mixed-phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force.

Orgel E, Alexander TB, Wood BL, Kahwash SB, Devidas M, Dai Y, Alonzo TA, Mullighan CG, Inaba H, Hunger SP, Raetz EA, Gamis AS, Rabin KR, Carroll AJ, Heerema NA, Berman JN, Woods WG, Loh ML, Zweidler-McKay PA, Horan JT,

Cancer.. 2020 February 1126 (3):593-601. Epub 10/29/2019.

Donor-specific anti-HLA antibodies in unrelated hematopoietic cell transplantation for non-malignant disorders.

Woolfrey A, Wang T, Lee SJ, Haagenson MD, Chen G, Fleischhauer K, Horan J, Hsu K, Verneris M, Spellman SR, Fernandez-Vina M

Bone marrow transplantation.. 2019 March 54 (3):494-496. Epub 09/19/2018.

The genetic basis and cell of origin of mixed phenotype acute leukaemia.

Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, Yeoh A, Reinhardt D, Tomizawa D, Kiyokawa N, Lammens T, De Moerloose B, Catchpoole D, Hori H, Moorman A, Moore AS, Hrusak O, Meshinchi S, Orgel E, Devidas M, Borowitz M, Wood B, Heerema NA, Carrol A, Yang YL, Smith MA, Davidsen TM, Hermida LC, Gesuwan P, Marra MA, Ma Y, Mungall AJ, Moore RA, Jones SJM, Valentine M, Janke LJ, Rubnitz JE, Pui CH, Ding L, Liu Y, Zhang J, Nichols KE, Downing JR, Cao X, Shi L, Pounds S, Newman S, Pei D, Guidry Auvil JM, Gerhard DS, Hunger SP, Inaba H, Mullighan CG

Nature.. 2018 October 562 (7727):373-379. Epub 09/12/2018.

Treatment strategies for adolescent and young adult patients with acute myeloid leukemia.

O'Dwyer K, Freyer DR, Horan JT

Blood.. 2018 July 26132 (4):362-368. Epub 06/12/2018.

Influence of Age on Acute and Chronic GVHD in Children Undergoing HLA-Identical Sibling Bone Marrow Transplantation for Acute Leukemia: Implications for Prophylaxis.

Qayed M, Wang T, Hemmer MT, Spellman S, Arora M, Couriel D, Alousi A, Pidala J, Abdel-Azim H, Aljurf M, Ayas M, Bitan M, Cairo M, Choi SW, Dandoy C, Delgado D, Gale RP, Hale G, Frangoul H, Kamble RT, Kharfan-Dabaja M, Lehman L, Levine J, MacMillan M, Marks DI, Nishihori T, Olsson RF, Hematti P, Ringden O, Saad A, Satwani P, Savani BN, Schultz KR, Seo S, Shenoy S, Waller EK, Yu L, Horowitz MM, Horan J

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2018 March 24 (3):521-528. Epub 11/16/2017.

Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival.

Raikar SS, Park SI, Leong T, Jaye DL, Keller FG, Horan JT, Woods WG

Blood.. 2018 February 1131 (5):573-577. Epub 12/09/2017.

Early blood stream infection following allogeneic hematopoietic stem cell transplantation is a risk factor for acute grade III-IV GVHD in children and adolescents.

Sano H, Hilinski JA, Qayed M, Applegate K, Newton JG, Watkins B, Chiang KY, Horan J

Pediatric blood & cancer.. 2018 February 65 (2)Epub 09/17/2017.

CD36-positive B-lymphoblasts Predict Poor Outcome in Children With B-lymphoblastic Leukemia.

Newton JG, Horan JT, Newman S, Rossi MR, Ketterling RP, Park SI

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.. 2017 June 20 (3):224-231. Epub 02/08/2017.

Recipient and donor age impact the risk of developing chronic GvHD in children after allogeneic hematopoietic transplant.

Watkins BK, Horan J, Storer B, Martin PJ, Carpenter PA, Flowers ME

Bone marrow transplantation.. 2017 April 52 (4):625-626. Epub 12/19/2016.

African American Race Is a Newly Identified Risk Factor for Postengraftment Blood Stream Infections in Pediatric Allogeneic Blood and Marrow Transplantation.

Sano H, Hilinski JA, Applegate K, Chiang KY, Haight A, Qayed M, Horan J

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2017 February 23 (2):357-360. Epub 11/10/2016.

Leukoreduced red blood cell transfusions do not induce platelet glycoprotein antibodies in patients with sickle cell disease.

Nickel RS, Winkler AM, Horan JT, Hendrickson JE

Transfusion.. 2016 September 56 (9):2267-73. Epub 07/06/2016.

Haematopoietic stem cell transplantation for sickle cell disease - current practice and new approaches.

Arnold SD, Bhatia M, Horan J, Krishnamurti L

British journal of haematology.. 2016 August 174 (4):515-25. Epub 06/02/2016.

Improved Splenic Function After Hematopoietic Stem Cell Transplant for Sickle Cell Disease.

Nickel RS, Seashore E, Lane PA, Alazraki AL, Horan JT, Bhatia M, Haight AE

Pediatric blood & cancer.. 2016 May 63 (5):908-13. Epub 01/12/2016.

Immunophenotypic parameters and RBC alloimmunization in children with sickle cell disease on chronic transfusion.

Nickel RS, Horan JT, Fasano RM, Meyer E, Josephson CD, Winkler AM, Yee ME, Kean LS, Hendrickson JE

American journal of hematology.. 2015 December 90 (12):1135-41. Epub 10/06/2015.

Use of Alefacept for Preconditioning in Multiply Transfused Pediatric Patients with Nonmalignant Diseases.

Stenger EO, Chiang KY, Haight A, Qayed M, Kean L, Horan J

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2015 October 21 (10):1845-52. Epub 06/19/2015.

Red blood cell transfusions are associated with HLA class I but not H-Y alloantibodies in children with sickle cell disease.

Nickel RS, Hendrickson JE, Yee MM, Bray RA, Gebel HM, Kean LS, Miklos DB, Horan JT

British journal of haematology.. 2015 July 170 (2):247-56. Epub 04/19/2015.

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCR? repertoire.

Suessmuth Y, Mukherjee R, Watkins B, Koura DT, Finstermeier K, Desmarais C, Stempora L, Horan JT, Langston A, Qayed M, Khoury HJ, Grizzle A, Cheeseman JA, Conger JA, Robertson J, Garrett A, Kirk AD, Waller EK, Blazar BR, Mehta AK, Robins HS, Kean LS

Blood.. 2015 June 18125 (25):3835-50. Epub 04/07/2015.

Using fludarabine to reduce exposure to alkylating agents in children with sickle cell disease receiving busulfan, cyclophosphamide, and antithymocyte globulin transplant conditioning: results of a dose de-escalation trial.

Horan JT, Haight A, Dioguardi JL, Brown C, Grizzle A, Shelman C, Kanter J, Hale G, Nieder M, Benton M, Kasow KA, Abraham A, Chiang KY

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2015 May 21 (5):900-5. Epub 01/21/2015.

Immune parameter analysis of children with sickle cell disease on hydroxycarbamide or chronic transfusion therapy.

Nickel RS, Osunkwo I, Garrett A, Robertson J, Archer DR, Promislow DE, Horan JT, Hendrickson JE, Kean LS

British journal of haematology.. 2015 May 169 (4):574-83. Epub 03/05/2015.

Risk for CMV reactivation in children undergoing allogeneic hematopoietic stem cell transplantation.

Qayed M, Khurana M, Hilinski J, Gillespie S, McCracken C, Applegate K, Chiang KY, Horan J

Pediatric blood & cancer.. 2015 February 62 (2):364-366. Epub 09/27/2014.

The Role of Intestinal Microbiota in Graft versus Host Disease.

Qayed M, Horan JT

Mini reviews in medicinal chemistry.. 2015 16 (3):193-9. Epub 1900 01 01.

Relative defects in mucosal immunity predict acute graft-versus-host disease.

August KJ, Chiang KY, Qayed M, Dulson A, Worthington-White D, Cole CR, Horan JT

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2014 July 20 (7):1056-9. Epub 03/15/2014.

Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome.

Hitzler JK, He W, Doyle J, Cairo M, Camitta BM, Chan KW, Diaz Perez MA, Fraser C, Gross TG, Horan JT, Kennedy-Nasser AA, Kitko C, Kurtzberg J, Lehmann L, O'Brien T, Pulsipher MA, Smith FO, Zhang MJ, Eapen M, Carpenter PA,

Pediatric blood & cancer.. 2014 June 61 (6):1126-8. Epub 01/04/2014.

Transplantation for children with acute myeloid leukemia: a comparison of outcomes with reduced intensity and myeloablative regimens.

Bitan M, He W, Zhang MJ, Abdel-Azim H, Ayas MF, Bielorai B, Carpenter PA, Cairo MS, Diaz MA, Horan JT, Jodele S, Kitko CL, Schultz KR, Kletzel M, Kasow KA, Lehmann LE, Mehta PA, Shah N, Pulsipher MA, Prestidge T, Seber A, Shenoy S, Woolfrey AE, Yu LC, Davies SM

Blood.. 2014 March 6123 (10):1615-20. Epub 01/16/2014.

Comparable survival for pediatric acute myeloid leukemia with poor-risk cytogenetics following chemotherapy, matched related donor, or unrelated donor transplantation.

Kelly MJ, Horan JT, Alonzo TA, Eapen M, Gerbing RB, He W, Lange BJ, Parsons SK, Woods WG

Pediatric blood & cancer.. 2014 February 61 (2):269-75. Epub 08/19/2013.

Effect of race on outcomes after allogeneic hematopoietic cell transplantation for severe aplastic anemia.

Eckrich MJ, Ahn KW, Champlin RE, Coccia P, Godder K, Horan J, Margolis D, Deeg HJ, Eapen M

American journal of hematology.. 2014 February 89 (2):125-9. Epub 11/15/2013.

Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients: a report from the Children's Oncology Group.

Canner J, Alonzo TA, Franklin J, Freyer DR, Gamis A, Gerbing RB, Lange BJ, Meshinchi S, Woods WG, Perentesis J, Horan J

Cancer.. 2013 December 1119 (23):4162-9. Epub 09/19/2013.

Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials.

Woods WG, Franklin AR, Alonzo TA, Gerbing RB, Donohue KA, Othus M, Horan J, Appelbaum FR, Estey EH, Bloomfield CD, Larson RA

Cancer.. 2013 December 1119 (23):4170-9. Epub 09/19/2013.

In vivo T cell costimulation blockade with abatacept for acute graft-versus-host disease prevention: a first-in-disease trial.

Koura DT, Horan JT, Langston AA, Qayed M, Mehta A, Khoury HJ, Harvey RD, Suessmuth Y, Couture C, Carr J, Grizzle A, Johnson HR, Cheeseman JA, Conger JA, Robertson J, Stempora L, Johnson BE, Garrett A, Kirk AD, Larsen CP, Waller EK, Kean LS

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2013 November 19 (11):1638-49. Epub 09/15/2013.

The impact of HLA unidirectional mismatches on the outcome of myeloablative hematopoietic stem cell transplantation with unrelated donors.

Hurley CK, Woolfrey A, Wang T, Haagenson M, Umejiego J, Aljurf M, Askar M, Battiwalla M, Dehn J, Horan J, Oudshoorn M, Pidala J, Saber W, Turner V, Lee SJ, Spellman SR

Blood.. 2013 June 6121 (23):4800-6. Epub 05/01/2013.

Outcome of transplantation for acute myelogenous leukemia in children with Down syndrome.

Hitzler JK, He W, Doyle J, Cairo M, Camitta BM, Chan KW, Diaz Perez MA, Fraser C, Gross TG, Horan JT, Kennedy-Nasser AA, Kitko C, Kurtzberg J, Lehmann L, O'Brien T, Pulsipher MA, Smith FO, Zhang MJ, Eapen M, Carpenter PA,

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2013 June 19 (6):893-7. Epub 03/01/2013.

Rifaximin for preventing acute graft-versus-host disease: impact on plasma markers of inflammation and T-cell activation.

Qayed M, Langston A, Chiang KY, August K, Hilinski JA, Cole CR, Rogatko A, Bostick RM, Horan JT

Journal of pediatric hematology/oncology.. 2013 May 35 (4):e149-52. Epub 1900 01 01.

Evaluation of HLA matching in unrelated hematopoietic stem cell transplantation for nonmalignant disorders.

Horan J, Wang T, Haagenson M, Spellman SR, Dehn J, Eapen M, Frangoul H, Gupta V, Hale GA, Hurley CK, Marino S, Oudshoorn M, Reddy V, Shaw P, Lee SJ, Woolfrey A

Blood.. 2012 October 4120 (14):2918-24. Epub 07/24/2012.

HLA-C antigen mismatch is associated with worse outcome in unrelated donor peripheral blood stem cell transplantation.

Woolfrey A, Klein JP, Haagenson M, Spellman S, Petersdorf E, Oudshoorn M, Gajewski J, Hale GA, Horan J, Battiwalla M, Marino SR, Setterholm M, Ringden O, Hurley C, Flomenberg N, Anasetti C, Fernandez-Vina M, Lee SJ

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2011 June 17 (6):885-92. Epub 09/24/2010.

Biomarkers of immune activation to screen for severe, acute GVHD.

August KJ, Chiang KY, Bostick RM, Flanders WD, Waller EK, Langston A, Worthington-White D, Rowland P, Moore KF, Khoury HJ, Horan JT

Bone marrow transplantation.. 2011 April 46 (4):601-4. Epub 07/12/2010.

Reducing the risk for transplantation-related mortality after allogeneic hematopoietic cell transplantation: how much progress has been made?

Horan JT, Logan BR, Agovi-Johnson MA, Lazarus HM, Bacigalupo AA, Ballen KK, Bredeson CN, Carabasi MH, Gupta V, Hale GA, Khoury HJ, Juckett MB, Litzow MR, Martino R, McCarthy PL, Smith FO, Rizzo JD, Pasquini MC

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2011 March 129 (7):805-13. Epub 01/10/2011.

HLA-matched sibling bone marrow transplantation for ?-thalassemia major.

Sabloff M, Chandy M, Wang Z, Logan BR, Ghavamzadeh A, Li CK, Irfan SM, Bredeson CN, Cowan MJ, Gale RP, Hale GA, Horan J, Hongeng S, Eapen M, Walters MC

Blood.. 2011 February 3117 (5):1745-50. Epub 11/30/2010.

Safety and efficacy of targeted busulfan therapy in children undergoing myeloablative matched sibling donor BMT for sickle cell disease.

McPherson ME, Hutcherson D, Olson E, Haight AE, Horan J, Chiang KY

Bone marrow transplantation.. 2011 January 46 (1):27-33. Epub 03/22/2010.

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression.

Miller WP, Srinivasan S, Panoskaltsis-Mortari A, Singh K, Sen S, Hamby K, Deane T, Stempora L, Beus J, Turner A, Wheeler C, Anderson DC, Sharma P, Garcia A, Strobert E, Elder E, Crocker I, Crenshaw T, Penedo MC, Ward T, Song M, Horan J, Larsen CP, Blazar BR, Kean LS

Blood.. 2010 December 9116 (24):5403-18. Epub 09/10/2010.

Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related, or matched unrelated donors.

Shaw PJ, Kan F, Woo Ahn K, Spellman SR, Aljurf M, Ayas M, Burke M, Cairo MS, Chen AR, Davies SM, Frangoul H, Gajewski J, Gale RP, Godder K, Hale GA, Heemskerk MB, Horan J, Kamani N, Kasow KA, Chan KW, Lee SJ, Leung WH, Lewis VA, Miklos D, Oudshoorn M, Petersdorf EW, Ringdén O, Sanders J, Schultz KR, Seber A, Setterholm M, Wall DA, Yu L, Pulsipher MA

Blood.. 2010 November 11116 (19):4007-15. Epub 07/29/2010.

Leukocyte adhesion deficiency-III in an African-American patient.

Sabnis H, Kirpalani A, Horan J, McDowall A, Svensson L, Cooley A, Merck T, Jobe S, Hogg N, Briones M

Pediatric blood & cancer.. 2010 July 1555 (1):180-2. Epub 1900 01 01.

Is the updated Schwartz formula appropriate for assessing renal function prior to hematopoietic stem cell transplantation?

Qayed M, Thompson A, Applegate K, Haight A, Rogatko A, Chiang KY, Horan J

Pediatric blood & cancer.. 2010 July 1555 (1):199-201. Epub 1900 01 01.

Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease.

Walters MC, Hardy K, Edwards S, Adamkiewicz T, Barkovich J, Bernaudin F, Buchanan GR, Bunin N, Dickerhoff R, Giller R, Haut PR, Horan J, Hsu LL, Kamani N, Levine JE, Margolis D, Ohene-Frempong K, Patience M, Redding-Lallinger R, Roberts IA, Rogers ZR, Sanders JE, Scott JP, Sullivan KM,

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2010 February 16 (2):263-72. Epub 10/12/2009.

Risk factors affecting outcome of second HLA-matched sibling donor transplantations for graft failure in severe acquired aplastic anemia.

Horan JT, Carreras J, Tarima S, Camitta BM, Gale RP, Hale GA, Hinterberger W, Marsh J, Passweg JR, Walters MC, Eapen M

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2009 May 15 (5):626-31. Epub 1900 01 01.

Impact of disease risk on efficacy of matched related bone marrow transplantation for pediatric acute myeloid leukemia: the Children's Oncology Group.

Horan JT, Alonzo TA, Lyman GH, Gerbing RB, Lange BJ, Ravindranath Y, Becton D, Smith FO, Woods WG,

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2008 December 1026 (35):5797-801. Epub 10/27/2008.

Risk factors for acute graft-versus-host disease after human leukocyte antigen-identical sibling transplants for adults with leukemia.

Hahn T, McCarthy PL, Zhang MJ, Wang D, Arora M, Frangoul H, Gale RP, Hale GA, Horan J, Isola L, Maziarz RT, van Rood JJ, Gupta V, Halter J, Reddy V, Tiberghien P, Litzow M, Anasetti C, Pavletic S, Ringdén O

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2008 December 1026 (35):5728-34. Epub 11/03/2008.

Matched-related donor transplantation for sickle cell disease: report from the Center for International Blood and Transplant Research.

Panepinto JA, Walters MC, Carreras J, Marsh J, Bredeson CN, Gale RP, Hale GA, Horan J, Hows JM, Klein JP, Pasquini R, Roberts I, Sullivan K, Eapen M, Ferster A,

British journal of haematology.. 2007 June 137 (5):479-85. Epub 04/24/2007.

Clinical outcomes and graft characteristics in pediatric matched sibling donor transplants using granulocyte colony-stimulating factor-primed bone marrow and steady-state bone marrow.

Chiang KY, Haight A, Horan J, Olson E, Gartner A, Hartman D, Youssef S, Worthington-White D

Pediatric transplantation.. 2007 May 11 (3):279-85. Epub 1900 01 01.

Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia.

Eggleston B, Patience M, Edwards S, Adamkiewicz T, Buchanan GR, Davies SC, Dickerhoff R, Donfield S, Feig SA, Giller RH, Haight A, Horan J, Hsu LL, Kamani N, Lane P, Levine JE, Margolis D, Moore TB, Ohene-Frempong K, Redding-Lallinger R, Roberts IA, Rogers ZR, Sanders JE, Scott JP, Sleight B, Thompson AA, Sullivan KM, Walters MC,

British journal of haematology.. 2007 February 136 (4):673-6. Epub 1900 01 01.

Prophylactic colony-stimulating factors in children receiving myelosuppressive chemotherapy: a meta-analysis of randomized controlled trials.

Wittman B, Horan J, Lyman GH

Cancer treatment reviews.. 2006 June 32 (4):289-303. Epub 05/05/2006.

A comparison of cyclophosphamide and total body irradiation with etoposide and total body irradiation as conditioning regimens for patients undergoing sibling allografting for acute lymphoblastic leukemia in first or second complete remission.

Marks DI, Forman SJ, Blume KG, Pérez WS, Weisdorf DJ, Keating A, Gale RP, Cairo MS, Copelan EA, Horan JT, Lazarus HM, Litzow MR, McCarthy PL, Schultz KR, Smith DD, Trigg ME, Zhang MJ, Horowitz MM

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2006 April 12 (4):438-53. Epub 1900 01 01.

Immunization to minor histocompatibility antigens on transfused RBCs through crosspriming into recipient MHC class I pathways.

Zimring JC, Hair GA, Deshpande SS, Horan JT

Blood.. 2006 January 1107 (1):187-9. Epub 08/25/2005.

Busulfan/melphalan/antithymocyte globulin followed by unrelated donor cord blood transplantation for treatment of infant leukemia and leukemia in young children: the Cord Blood Transplantation study (COBLT) experience.

Wall DA, Carter SL, Kernan NA, Kapoor N, Kamani NR, Brochstein JA, Frangoul H, Goyal RK, Horan JT, Pietryga D, Wagner JE, Kurtzberg J,

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2005 August 11 (8):637-46. Epub 1900 01 01.

Hematopoietic stem cell transplantation for multiply transfused patients with sickle cell disease and thalassemia after low-dose total body irradiation, fludarabine, and rabbit anti-thymocyte globulin.

Horan JT, Liesveld JL, Fenton P, Blumberg N, Walters MC

Bone marrow transplantation.. 2005 January 35 (2):171-7. Epub 1900 01 01.

A 2-year-old with atypical CML with a t(5;12)(q33;p13) treated successfully with imatinib mesylate.

Wittman B, Horan J, Baxter J, Goldberg J, Felgar R, Baylor E, Cromwell B, Cross N, Bennett JM

Leukemia research.. 2004 May 28 Suppl 1 :S65-9. Epub 1900 01 01.

Survival after HLA-identical allogeneic peripheral blood stem cell and bone marrow transplantation for hematologic malignancies: meta-analysis of randomized controlled trials.

Horan JT, Liesveld JL, Fernandez ID, Lyman GH, Phillips GL, Lerner NB, Fisher SG

Bone marrow transplantation.. 2003 August 32 (3):293-8. Epub 1900 01 01.

Fibrin degradation products, fibrin monomer and soluble fibrin in disseminated intravascular coagulation.

Horan JT, Francis CW

Seminars in thrombosis and hemostasis.. 2001 December 27 (6):657-66. Epub 1900 01 01.

Prothrombotic changes in hemostatic parameters and C-reactive protein in the elderly with winter acute respiratory tract infections.

Horan JT, Francis CW, Falsey AR, Kolassa J, Smith BH, Hall WJ

Thrombosis and haemostasis.. 2001 February 85 (2):245-9. Epub 1900 01 01.

Allogeneic bone marrow transplantation for children with acute leukemia: cytoreduction with fractionated total body irradiation, high-dose etoposide and cyclophosphamide.

Duerst RE, Horan JT, Liesveld JL, Abboud CN, Zwetsch LM, Senf ES, Constine LS, Raubertas RF, Passarell JA, DiPersio JF

Bone marrow transplantation.. 2000 March 25 (5):489-94. Epub 1900 01 01.

Automated latex agglutination and ELISA testing yield equivalent D-dimer results in patients with recent myocardial infarction. THROMBO Research Investigators.

Marder VJ, Zareba W, Horan JT, Moss AJ, Kanouse JJ

Thrombosis and haemostasis.. 1999 November 82 (5):1412-6. Epub 1900 01 01.

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