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Neil Blumberg, M.D.

Neil Blumberg, M.D.

UR Medicine Labs

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About Me

Director of the Transfusion Medicine Unit, Blood Bank, and Stem Cell Storage Facility since 1980. An expert in the field of blood transfusion immunology, Dr. Blumberg has worked to enhance the quality, safety, and efficiency of transfusion services at Strong Memorial Hospital and across the broader ...
Director of the Transfusion Medicine Unit, Blood Bank, and Stem Cell Storage Facility since 1980. An expert in the field of blood transfusion immunology, Dr. Blumberg has worked to enhance the quality, safety, and efficiency of transfusion services at Strong Memorial Hospital and across the broader medical community. His long-standing clinical and research foci are immune cytopenias, supportive care for patients with hematologic malignancies, and the immunologic sequela of transfusion therapy.

Certified Specialties

Pathology, Clinical Pathology/Laboratory Medicine - American Board of Pathology

Faculty Appointments

Professor - Department of Pathology and Laboratory Medicine (SMD)

Credentials

Residency & Fellowship

Residency, Yale New Haven Hospital Temple Medical Center. 1976 - 1978

Internship, Yale New Haven Hospital Temple Medical Center. 1975 - 1976

Education

MD | Yale University School of Medicine. 1975

Awards

Editorial Board Member. 2008 - 2012

Co-Chair REDS III and Chair REDS II Data Monitoring Committee. 2005 - 2018

Editorial Board Member. 1990

NIH Medical Scientist Training Grant
Fellowship
1971 - 1974

BS, Yale, Magna cum laude 1970

Phi Beta Kappa 1969

National Merit Scholarship Program. 1966 - 1970

Research

Blood transfusions are known to be broadly immunomodulatory and are associated with substantially poorer clinical outcomes in surgical and cancer patients, and better outcomes in solid organ allograft recipients. Our laboratory and clinical group has been interested for the last twenty years in the ...
Blood transfusions are known to be broadly immunomodulatory and are associated with substantially poorer clinical outcomes in surgical and cancer patients, and better outcomes in solid organ allograft recipients. Our laboratory and clinical group has been interested for the last twenty years in the disparate effects of autologous and allogeneic transfusions on immune function, as well as the potential benefits of removing allogeneic white cells and stored supernatant plasma from blood components before transfusions.

Our studies demonstrated that patients receiving leukocyte-reduced allogeneic blood transfusions for leukemia, and those receiving leukocyte-reduced allogeneic or autologous transfusions during surgical procedures, experienced reduced morbidity and mortality compared with patients receiving unmodified allogeneic transfusions. We were the first to document that one likely mechanism for these benefits is that allogeneic transfusions promote type 2 (Th2) cellular immunity and down regulate type 1 (Th1) immunity. Leukoreduction or use of autologous transfusions reduces these immunologic effects. We also have pioneered clinical outcomes and cost-effectiveness analyses in the study of transfusion immunomodulation.

Transfusions, however, can also promote inflammatory processes. Platelet transfusions are associated with a dose dependent increase in multi-organ failure syndrome in surgical patients. Work done in collaboration with Dr. Rick Phipps's laboratory has shown that stored platelet transfusion supernatant promotes cellular secretion of PGE2 , IL6 and IL8 in vitro through a soluble CD40L dependent mechanism. Current investigations include clinical and laboratory studies of the effects of stored platelet supernatant CD40L on clinical outcomes and in vitro immunologic function. We are also exploring the possible use of autologous stored platelet supernatant for immunotherapeutic use.

Publications

Journal Articles

Platelet Transfusions, Mortality, and ABO Identicality in Premature Newborns.

Asante A, Nguyen P, Henrichs K, Masel D, Refaai M, Blumberg N

American journal of perinatology.. 2024 August 41 (11):1592-1593. Epub 10/20/2023.

Platelet Transfusions: The Good, the Bad, and the Ugly.

Blumberg N, Asante AA, Nguyen PT, Heal JM

Anesthesia and analgesia.. 2024 May 1138 (5):921-924. Epub 04/15/2024.

In response: ABO nonidentical platelet transfusions and mortality.

Blumberg N, Nguyen PL, Asante A, Masel D, Henrichs K, Refaai M, Heal J, Love T

Transfusion.. 2024 May 64 (5):954-956. Epub 1900 01 01.

ABO blood group, ABO mismatched transfusions and leukoreduction of transfusions in hemostatic resuscitation studies.

Nguyen PL, Asante A, Refaai M, Blumberg N

Frontiers in bioengineering and biotechnology.. 2024 12 :1437471. Epub 09/16/2024.

A commentary on the optimal red blood cell transfusion threshold in acute leukemia patients.

Asante A, Nguyen PL, Blumberg N

Blood transfusion = Trasfusione del sangue.. 2023 November 421 (6):461-462. Epub 1900 01 01.

Patient blood management: Myths and facts about red blood cell transfusions.

Gammon RR, Blumberg N, Gilstad C, Mandal S, Nair AR, Bocquet C

Vox sanguinis.. 2023 July 118 (7):509-516. Epub 05/22/2023.

Association of crystalloid fluid infusion with intravascular hemolysis and organ dysfunction in hematopoietic stem cell transplant patients.

Holloway MR, Fountaine T, Henrichs K, Feeney T, Andolina J, O'Dwyer K, Liesveld J, Blumberg N, Huselton E

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.. 2023 June 62 (3):103641. Epub 01/13/2023.

Reduction of anti-A and anti-B isoagglutinin titers of group O whole blood units employing an ABO antibody immune adsorption column.

Gupta GK, Henrichs K, Nilsson K, Wagner S, Brown B, Masel D, Gestring ML, Vella MA, Refaai MA, Blumberg N

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.. 2023 June 62 (3):103686. Epub 03/05/2023.

How do we forecast tomorrow's transfusion? - Next generation transfusion practices to improve recipient safety.

Blumberg N, Mary Heal J

Transfusion clinique et biologique : journal de la Société française de transfusion sanguine.. 2023 February 30 (1):31-34. Epub 09/09/2022.

National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies.

Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL

Transfusion.. 2022 November 62 (11):2391-2404. Epub 09/28/2022.

Patient Blood Management: Improving Outcomes for Millions While Saving Billions. What Is Holding It Up?

Hofmann A, Shander A, Blumberg N, Hamdorf JM, Isbister JP, Gross I

Anesthesia and analgesia.. 2022 September 1135 (3):511-523. Epub 08/17/2022.

Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption.

McRae HL, Millar MW, Slavin SA, Blumberg N, Rahman A, Refaai MA

Biomedicines.. 2021 December 79 (12)Epub 12/07/2021.

Preoperative anemia management program reduces blood transfusion in elective cardiac surgical patients, improving outcomes and decreasing hospital length of stay.

Cahill CM, Alhasson B, Blumberg N, Melvin A, Knight P, Gloff M, Robinson R, Akwaa F, Refaai MA

Transfusion.. 2021 September 61 (9):2629-2636. Epub 07/15/2021.

Reducing the Need for HLA-Matched Platelet Transfusion.

Cardillo A, Heal JM, Henrichs K, Masel D, Fountaine T, Liesveld J, Noronha S, Cahill C, Ngo A, Gupta GK, Refaai MA, Blumberg N

The New England journal of medicine.. 2021 June 24384 (25):2451-2452. Epub 1900 01 01.

Impact of RBC Transfusion on Peripheral Capillary Oxygen Saturation and Partial Pressure of Arterial Oxygen.

Turgeman A, McRae HL, Cahill C, Blumberg N, Refaai MA

American journal of clinical pathology.. 2021 June 17156 (1):149-154. Epub 1900 01 01.

Whole blood haemostatic function throughout a 28-day cold storage period: an in vitro study.

McRae HL, Kara F, Milito C, Cahill C, Blumberg N, Refaai MA

Vox sanguinis.. 2021 February 116 (2):190-196. Epub 09/23/2020.

Blood Banking and Transfusion Medicine Challenges During the COVID-19 Pandemic.

Ngo A, Masel D, Cahill C, Blumberg N, Refaai MA

Clinics in laboratory medicine.. 2020 December 40 (4):587-601. Epub 08/08/2020.

Evaluation of the procoagulant properties of a newly developed platelet modified lysate product.

Refaai MA, Conley GW, Hudson CA, Spinelli SL, Phipps RP, Morrell CN, Blumberg N, McRae HL

Transfusion.. 2020 July 60 (7):1579-1589. Epub 05/15/2020.

Allogeneic Leukocyte-Reduced Red Blood Cell Transfusion Is Associated with Postoperative Infectious Complications and Cancer Recurrence after Colon Cancer Resection.

Deeb AP, Aquina CT, Monson JRT, Blumberg N, Becerra AZ, Fleming FJ

Digestive surgery.. 2020 37 (2):163-170. Epub 03/05/2019.

Post-Transfusion Purpura Mimicking Idiopathic Thrombocytopenic Purpura: A Case Report.

Milito C, Masel D, Henrichs K, Schmidt AE, Kirkley S, Aljitawi O, Becker M, Blumberg N, Refaai MA

Laboratory medicine.. 2019 October 1050 (4):396-400. Epub 1900 01 01.

Transfusion medicine: A research agenda for the coming years.

Blumberg N, Cholette JM, Cahill C, Pietropaoli AP, Winters S, Phipps R, Noronha SA, Heal JM, Kirkley SA, Fountaine TJ, Henrichs K, Masel D, Refaai MA

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.. 2019 October 58 (5):698-700. Epub 08/06/2019.

Transfusing fresh red blood cells might be dangerous.

Blumberg N

BMJ : British medical journal. 2019 August 5366 :l4968. Epub 08/05/2019.

Met-Hemoglobin Is a Biomarker for Poor Oxygen Delivery in Infants Following Surgical Palliation.

Swartz MF, Makhija P, Rubenstein J, Henrichs KF, Powers KS, Wang HY, Simon BV, Alfieris GM, Blumberg N, Cholette JM

World journal for pediatric & congenital heart surgery.. 2019 July 10 (4):485-491. Epub 05/29/2019.

Total plasma heme concentration increases after red blood cell transfusion and predicts mortality in critically ill medical patients.

Pietropaoli AP, Henrichs KF, Cholette JM, Spinelli SL, Phipps RP, Refaai MA, Blumberg N

Transfusion.. 2019 June 59 (6):2007-2015. Epub 02/27/2019.

Sickle red blood cells are more susceptible to in vitro haemolysis when exposed to normal saline versus Plasma-Lyte A.

Blumberg N, Henrichs K, Cholette J, Pietropaoli A, Spinelli S, Noronha S, Phipps R, Refaai MA

Vox sanguinis.. 2019 May 114 (4):325-329. Epub 04/02/2019.

A Randomized Trial of Neonatal Platelet Transfusion Thresholds.

Blumberg N

The New England journal of medicine.. 2019 April 18380 (16):1584. Epub 1900 01 01.

The effect of red blood cell transfusion on iron metabolism in critically ill patients.

Boshuizen M, van Hezel, van Manen, Straat M, Somsen YBO, Spoelstra-de Man, Blumberg N, van Bruggen, Juffermans NP

Transfusion.. 2019 April 59 (4):1196-1201. Epub 12/31/2018.

Clinical lessons learned from a case of suspected transfusion-transmitted malaria.

Noronha S, Weinberg GA, Sorensen B, Evans AG, Blumberg N

Transfusion.. 2019 March 59 (3):1159. Epub 1900 01 01.

Placental Chorionic Cyst Fluid Has Prothrombotic Properties and Differs From Amniotic Fluid.

Stolla M, Refaai MA, Conley G, Spinelli S, Casey A, Katerji H, McRae HL, Blumberg N, Phipps R, Metlay LA, Katzman PJ

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.. 2019 22 (4):304-314. Epub 01/02/2019.

The HIV protease inhibitor, ritonavir, dysregulates human platelet function in vitro.

Loelius SG, Lannan KL, Blumberg N, Phipps RP, Spinelli SL

Thrombosis research.. 2018 September 169 :96-104. Epub 07/06/2018.

Decreased Hemolysis and Improved Platelet Function in Blood Components Washed With Plasma-Lyte A Compared to 0.9% Sodium Chloride.

Refaai MA, Conley GW, Henrichs KF, McRae H, Schmidt AE, Phipps RP, Spinelli SL, Masel D, Cholette JM, Pietropaoli A, Eaton MP, Blumberg N

American journal of clinical pathology.. 2018 July 3150 (2):146-153. Epub 1900 01 01.

Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures, and altered inflammatory markers in pediatric cardiac surgery patients.

Cholette JM, Pietropaoli AP, Henrichs KF, Alfieris GM, Powers KS, Gensini F, Rubenstein JS, Sweeney D, Phipps R, Spinelli SL, Refaai MA, Eaton MP, Blumberg N

Transfusion.. 2018 July 58 (7):1631-1639. Epub 03/30/2018.

Is It Time to Reconsider the Concepts of "Universal Donor" and "ABO Compatible" Transfusions?

Refaai MA, Cahill C, Masel D, Schmidt AE, Heal JM, Kirkley SA, Blumberg N

Anesthesia and analgesia.. 2018 June 126 (6):2135-2138. Epub 1900 01 01.

Indications for red cell transfusions in pediatric patients.

Cholette JM, Noronha SA, Seghatchian J, Blumberg N

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.. 2018 June 57 (3):342-346. Epub 05/10/2018.

Implementation of a Standardized Transfusion Protocol for Cardiac Patients Treated With Venoarterial Extracorporeal Membrane Oxygenation Is Associated With Decreased Blood Component Utilization and May Improve Clinical Outcome.

Cahill CM, Blumberg N, Schmidt AE, Knight PA, Melvin AL, Massey HT, Delehanty JM, Zebrak SB, Refaai MA

Anesthesia and analgesia.. 2018 April 126 (4):1262-1267. Epub 1900 01 01.

Mechanisms of red blood cell transfusion-related immunomodulation.

Remy KE, Hall MW, Cholette J, Juffermans NP, Nicol K, Doctor A, Blumberg N, Spinella PC, Norris PJ, Dahmer MK, Muszynski JA,

Transfusion.. 2018 March 58 (3):804-815. Epub 01/30/2018.

The precautionary principle and use of Group A plasma in recipients of unknown ABO blood group.

Blumberg N, Heal JM, Masel D, Refaai MA

Transfusion.. 2018 March 58 (3):829-831. Epub 1900 01 01.

Oxidation Reduction Potential (ORP) is Predictive of Complications Following Pediatric Cardiac Surgery.

Schmidt AE, Gore E, Henrichs KF, Conley G, Dorsey C, Bjugstad KB, Refaai MA, Blumberg N, Cholette JM

Pediatric cardiology.. 2018 February 39 (2):299-306. Epub 10/31/2017.

0.9% NaCl (Normal Saline) - Perhaps not so normal after all?

Blumberg N, Cholette JM, Pietropaoli AP, Phipps R, Spinelli SL, Eaton MP, Noronha SA, Seghatchian J, Heal JM, Refaai MA

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.. 2018 February 57 (1):127-131. Epub 02/21/2018.

Haem is associated with thrombosis in neonates and infants undergoing cardiac surgery for congenital heart disease.

Stolla M, Henrichs K, Cholette JM, Pietropaoli AP, Phipps RP, Spinelli SL, Blumberg N

Vox sanguinis.. 2018 January 113 (1):72-75. Epub 10/16/2017.

Prophylactic Preprocedure Platelet Transfusion Is Associated With Increased Risk of Thrombosis and Mortality.

Schmidt AE, Henrichs KF, Kirkley SA, Refaai MA, Blumberg N

American journal of clinical pathology.. 2017 December 20149 (1):87-94. Epub 1900 01 01.

ABO identical and washed blood transfusions as candidate strategies to reduce early mortality in acute promyelocytic leukemia.

Sahai T, Henrichs K, Refaai M, Heal JM, Kirkley SA, Schmidt AE, Mendler JH, Masel D, Liesveld J, Aquina C, Blumberg N

Leukemia research.. 2017 November 62 :1-3. Epub 09/23/2017.

Management of Platelet Disorders and Platelet Transfusions in ICU Patients.

Blumberg N, Cholette JM, Schmidt AE, Phipps RP, Spinelli SL, Heal JM, Pietropaoli AP, Refaai MA, Sime PJ

Transfusion medicine reviews.. 2017 October 31 (4):252-257. Epub 05/04/2017.

Association Among Blood Transfusion, Sepsis, and Decreased Long-term Survival After Colon Cancer Resection.

Aquina CT, Blumberg N, Becerra AZ, Boscoe FP, Schymura MJ, Noyes K, Monson JR, Fleming FJ

Annals of surgery.. 2017 August 266 (2):311-317. Epub 1900 01 01.

Maresin 1 induces a novel pro-resolving phenotype in human platelets.

Lannan KL, Spinelli SL, Blumberg N, Phipps RP

Journal of thrombosis and haemostasis : JTH.. 2017 April 15 (4):802-813. Epub 02/25/2017.

Outcomes Using a Conservative Versus Liberal Red Blood Cell Transfusion Strategy in Infants Requiring Cardiac Operation.

Cholette JM, Swartz MF, Rubenstein J, Henrichs KF, Wang H, Powers KS, Daugherty LE, Alfieris GM, Gensini F, Blumberg N

The Annals of thoracic surgery.. 2017 January 103 (1):206-214. Epub 08/03/2016.

Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness.

Muszynski JA, Spinella PC, Cholette JM, Acker JP, Hall MW, Juffermans NP, Kelly DP, Blumberg N, Nicol K, Liedel J, Doctor A, Remy KE, Tucci M, Lacroix J, Norris PJ,

Transfusion.. 2017 January 57 (1):195-206. Epub 10/02/2016.

Improved outcomes in acute myeloid leukemia patients treated with washed transfusions.

Greener D, Henrichs KF, Liesveld JL, Heal JM, Aquina CT, Phillips GL, Kirkley SA, Milner LA, Refaai MA, Mendler JH, Szydlowski J, Masel D, Schmidt A, Boscoe FP, Schymura MJ, Blumberg N

American journal of hematology.. 2017 January 92 (1):E8-E9. Epub 1900 01 01.

NF-?B Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets.

Damien P, Cognasse F, Payrastre B, Spinelli SL, Blumberg N, Arthaud CA, Eyraud MA, Phipps RP, McNicol A, Pozzetto B, Garraud O, Hamzeh-Cognasse H

Frontiers in immunology.. 2017 8 :85. Epub 02/06/2017.

Association between delivery methods for red blood cell transfusion and the risk of venous thromboembolism: a longitudinal study.

Rogers MA, Blumberg N, Bernstein SJ, Flanders SA, Chopra V

The Lancet. Haematology.. 2016 December 3 (12):e563-e571. Epub 11/03/2016.

Large Variation in Blood Transfusion Use After Colorectal Resection: A Call to Action.

Aquina CT, Blumberg N, Probst CP, Becerra AZ, Hensley BJ, Noyes K, Monson JR, Fleming FJ

Diseases of the colon and rectum.. 2016 May 59 (5):411-8. Epub 1900 01 01.

ABO-immune complex formation and impact on platelet function, red cell structural integrity and haemostasis: an in vitro model of ABO non-identical transfusion.

Zaffuto BJ, Conley GW, Connolly GC, Henrichs KF, Francis CW, Heal JM, Blumberg N, Refaai MA

Vox sanguinis.. 2016 April 110 (3):219-26. Epub 11/03/2015.

Haemovigilance of reactions associated with red blood cell transfusion: comparison across 17 Countries.

Rogers MA, Rohde JM, Blumberg N

Vox sanguinis.. 2016 April 110 (3):266-77. Epub 12/21/2015.

Improving platelet transfusion safety: biomedical and technical considerations.

Garraud O, Cognasse F, Tissot JD, Chavarin P, Laperche S, Morel P, Lefrère JJ, Pozzetto B, Lozano M, Blumberg N, Osselaer JC

Blood transfusion = Trasfusione del sangue.. 2016 March 14 (2):109-22. Epub 11/16/2015.

Resveratrol preserves the function of human platelets stored for transfusion.

Lannan KL, Refaai MA, Ture SK, Morrell CN, Blumberg N, Phipps RP, Spinelli SL

British journal of haematology.. 2016 March 172 (5):794-806. Epub 12/18/2015.

Platelet Transfusion and Thrombosis: More Questions than Answers.

Schmidt AE, Refaai MA, Blumberg N

Seminars in thrombosis and hemostasis.. 2016 March 42 (2):118-24. Epub 12/30/2015.

Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis.

Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH

Blood.. 2016 January 28127 (4):400-10. Epub 12/01/2015.

Past, present and forecast of transfusion medicine: What has changed and what is expected to change?

Schmidt AE, Refaai MA, Blumberg N

La Presse me?dicale.. 2016 45 (7-8 Pt 2):e253-72. Epub 07/26/2016.

Significant Variation in Blood Transfusion Practice Persists following Upper GI Cancer Resection.

Aquina CT, Blumberg N, Probst CP, Becerra AZ, Hensley BJ, Iannuzzi JC, Gonzalez MG, Deeb AP, Noyes K, Monson JR, Fleming FJ

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2015 November 19 (11):1927-37. Epub 08/12/2015.

The rise, fall and future of red blood cell transfusions.

Blumberg N

MLO: medical laboratory observer.. 2015 October 47 (10):24. Epub 1900 01 01.

2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.

Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S,

Transfusion.. 2015 September 55 (9):2282-90. Epub 08/10/2015.

An alternative method to dithiothreitol treatment for antibody screening in patients receiving daratumumab.

Schmidt AE, Kirkley S, Patel N, Masel D, Bowen R, Blumberg N, Refaai MA

Transfusion.. 2015 September 55 (9):2292-3. Epub 1900 01 01.

ABO matching of platelet transfusions - "Start Making Sense". "As we get older, and stop making sense…" - The Talking Heads (1984).

Blumberg N, Refaai M, Heal J

Blood transfusion = Trasfusione del sangue.. 2015 July 13 (3):347-50. Epub 02/02/2015.

Longer RBC storage duration is associated with increased postoperative infections in pediatric cardiac surgery.

Cholette JM, Pietropaoli AP, Henrichs KF, Alfieris GM, Powers KS, Phipps R, Spineli SL, Swartz M, Gensini F, Daugherty LE, Nazarian E, Rubenstein JS, Sweeney D, Eaton M, Blumberg N

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2015 March 16 (3):227-35. Epub 1900 01 01.

Platelet transfusion - the new immunology of an old therapy.

Stolla M, Refaai MA, Heal JM, Spinelli SL, Garraud O, Phipps RP, Blumberg N

Frontiers in immunology.. 2015 6 :28. Epub 02/02/2015.

Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles.

Lannan KL, Sahler J, Kim N, Spinelli SL, Maggirwar SB, Garraud O, Cognasse F, Blumberg N, Phipps RP

Frontiers in immunology.. 2015 6 :48. Epub 02/13/2015.

Removal of biologic response modifiers associated with platelet transfusion reactions: strategies worth considering?

Garraud O, Cognasse F, Hamzeh-Cognasse H, Spinelli S, Phipps RP, Blumberg N

Transfusion.. 2014 October 54 (10):2583. Epub 1900 01 01.

Isoprostane and isofuran lipid mediators accumulate in stored red blood cells and influence platelet function in vitro.

Spinelli SL, Lannan KL, Casey AE, Croasdell A, Curran TM, Henrichs KF, Pollock SJ, Milne GA, Refaai MA, Francis CW, Phipps RP, Blumberg N

Transfusion.. 2014 June 54 (6):1569-79. Epub 11/05/2013.

Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis.

Rohde JM, Dimcheff DE, Blumberg N, Saint S, Langa KM, Kuhn L, Hickner A, Rogers MA

JAMA.. 2014 April 2311 (13):1317-26. Epub 1900 01 01.

Association between surgical resident involvement and blood use in noncardiac surgery.

Glance LG, Mukamel DB, Blumberg N, Fleming FJ, Hohmann SF, Dick AW

Transfusion.. 2014 March 54 (3):691-700. Epub 07/25/2013.

ABO mismatched platelet transfusions in trauma patients.

Blumberg N

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.. 2014 January 7186 (1):63. Epub 1900 01 01.

Preoperative thrombocytopenia and postoperative outcomes after noncardiac surgery.

Glance LG, Blumberg N, Eaton MP, Lustik SJ, Osler TM, Wissler R, Zollo R, Karcz M, Feng C, Dick AW

Anesthesiology.. 2014 January 120 (1):62-75. Epub 1900 01 01.

Storage duration of red blood cell transfusion and Clostridium difficile infection: a within person comparison.

Rogers MA, Micic D, Blumberg N, Young VB, Aronoff DM

PloS one.. 2014 9 (2):e89332. Epub 02/21/2014.

Transfusion immunomodulation from a clinical perspective: an update.

Refaai MA, Blumberg N

Expert review of hematology.. 2013 December 6 (6):653-63. Epub 10/30/2013.

The transfusion dilemma--weighing the known and newly proposed risks of blood transfusions against the uncertain benefits.

Refaai MA, Blumberg N

Best practice & research. Clinical anaesthesiology.. 2013 March 27 (1):17-35. Epub 1900 01 01.

Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -B.

Refaai MA, Carter J, Henrichs KF, Davidson DC, Pollock SJ, Casey AE, Spinelli SL, Phipps RP, Francis CW, Blumberg N

Transfusion.. 2013 February 53 (2):382-93. Epub 05/25/2012.

Transfusion of cell saver salvaged blood in neonates and infants undergoing open heart surgery significantly reduces RBC and coagulant product transfusions and donor exposures: results of a prospective, randomized, clinical trial.

Cholette JM, Powers KS, Alfieris GM, Angona R, Henrichs KF, Masel D, Swartz MF, Daugherty LE, Belmont K, Blumberg N

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2013 February 14 (2):137-47. Epub 1900 01 01.

Transfusion immunomodulation--the case for leukoreduced and (perhaps) washed transfusions.

Lannan KL, Sahler J, Spinelli SL, Phipps RP, Blumberg N

Blood cells, molecules & diseases.. 2013 January 50 (1):61-8. Epub 09/13/2012.

A novel method for overexpression of peroxisome proliferator-activated receptor-? in megakaryocyte and platelet microparticles achieves transcellular signaling.

Sahler J, Woeller C, Spinelli S, Blumberg N, Phipps R

Journal of thrombosis and haemostasis : JTH.. 2012 December 10 (12):2563-72. Epub 1900 01 01.

Measures to prevent transfusion-related acute lung injury (TRALI).

Reesink HW, Lee J, Keller A, Dennington P, Pink J, Holdsworth R, Schennach H, Goldman M, Petraszko T, Sun J, Meng Y, Qian K, Rehacek V, Turek P, Krusius T, Juvonen E, Tiberghien P, Legrand D, Semana G, Muller JY, Bux J, Reil A, Lin CK, Daly H, McSweeney E, Porretti L, Greppi N, Rebulla P, Okazaki H, Sánchez-Guerrero SA, Baptista-González HA, Martínez-Murillo C, Guerra-Márquez A, Rodriguez-Moyado H, Middelburg RA, Wiersum-Osselton JC, Brand A, van Tilburg C, Dinesh D, Dagger J, Dunn P, Brojer E, Letowska M, Maslanka K, Lachert E, Uhrynowska M, Zhiburt E, Palfi M, Berlin G, Frey BM, Puig Rovira L, Muñiz-Diaz E, Castro E, Chapman C, Green A, Massey E, Win N, Williamson L, Silliman CC, Chaffin DJ, Ambruso DR, Blumberg N, Tomasulo P, Land KJ, Norris PJ, Illoh OC, Davey RJ, Benjamin RJ, Eder AF, McLaughlin L, Kleinman S, Panzer S

Vox sanguinis.. 2012 October 103 (3):231-59. Epub 04/20/2012.

CD40 ligand (CD154) involvement in platelet transfusion reactions.

Sahler J, Spinelli S, Phipps R, Blumberg N

Transfusion clinique et biologique : journal de la Société française de transfusion sanguine.. 2012 June 19 (3):98-103. Epub 06/14/2012.

Triggers of hospitalization for venous thromboembolism.

Rogers MA, Levine DA, Blumberg N, Flanders SA, Chopra V, Langa KM

Circulation.. 2012 May 1125 (17):2092-9. Epub 04/03/2012.

Antigenic challenge in the etiology of autoimmune disease in women.

Rogers MA, Levine DA, Blumberg N, Fisher GG, Kabeto M, Langa KM

Journal of autoimmunity.. 2012 May 38 (2-3):J97-J102. Epub 08/30/2011.

Washing red blood cells and platelets transfused in cardiac surgery reduces postoperative inflammation and number of transfusions: results of a prospective, randomized, controlled clinical trial.

Cholette JM, Henrichs KF, Alfieris GM, Powers KS, Phipps R, Spinelli SL, Swartz M, Gensini F, Daugherty LE, Nazarian E, Rubenstein JS, Sweeney D, Eaton M, Lerner NB, Blumberg N

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2012 May 13 (3):290-9. Epub 1900 01 01.

Providing ABO-identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidence.

Henrichs KF, Howk N, Masel DS, Thayer M, Refaai MA, Kirkley SA, Heal JM, Blumberg N

Transfusion.. 2012 March 52 (3):635-40. Epub 09/02/2011.

ABO-mismatched transfusions are not over-represented in febrile non-haemolytic transfusion reactions to platelets.

Yazer MH, Raval JS, Triulzi DJ, Blumberg N

Vox sanguinis.. 2012 February 102 (2):175-7. Epub 07/22/2011.

The mystery of transfusion-related acute lung injury.

Blumberg N, Sime PJ, Phipps RP

Transfusion.. 2011 October 51 (10):2054-7. Epub 1900 01 01.

Role of transfusion in the development of urinary tract-related bloodstream infection.

Rogers MA, Blumberg N, Heal JM, Kuhn L, Greene MT, Shuman E, Chenoweth CE, Chang R, Saint S

Archives of internal medicine.. 2011 September 26171 (17):1587-9. Epub 1900 01 01.

Does the storage duration of blood products affect outcomes in critically ill patients?

Spinella PC, Doctor A, Blumberg N, Holcomb JB

Transfusion.. 2011 August 51 (8):1644-50. Epub 1900 01 01.

An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients.

Refaai MA, Fialkow LB, Heal JM, Henrichs KF, Spinelli SL, Phipps RP, Masel E, Smith BH, Corsetti JP, Francis CW, Bankey PE, Blumberg N

Vox sanguinis.. 2011 July 101 (1):55-60. Epub 03/18/2011.

The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-?B inhibition.

Sahler J, Bernard JJ, Spinelli SL, Blumberg N, Phipps RP

Thrombosis research.. 2011 May 127 (5):426-34. Epub 01/26/2011.

Utilization of blood transfusion among older adults in the United States.

Rogers MA, Blumberg N, Heal JM, Langa KM

Transfusion.. 2011 April 51 (4):710-8. Epub 11/18/2010.

Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomes.

Refaai MA, Phipps RP, Spinelli SL, Blumberg N

Thrombosis research.. 2011 April 127 (4):287-91. Epub 11/19/2010.

New frontiers in transfusion biology: identification and significance of mediators of morbidity and mortality in stored red blood cells.

Grimshaw K, Sahler J, Spinelli SL, Phipps RP, Blumberg N

Transfusion.. 2011 April 51 (4):874-80. Epub 1900 01 01.

Platelet Activation Following Exposure to Anti-ABO Antibodies-An In Vitro Study.

Refaai MA, Henrichs KF, Spinelli SL, Phipps RP, Masel E, Smith BH, Francis CW, Blumberg N

US oncology & hematology.. 2011 January 17 (1):72-74. Epub 1900 01 01.

Platelet storage and transfusions: new concerns associated with an old therapy.

Sahler J, Grimshaw K, Spinelli SL, Refaai MA, Phipps RP, Blumberg N

Drug discovery today. Disease mechanisms. 2011 8 (1-2):e9-e14. Epub 07/20/2011.

An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusions.

Blumberg N, Heal JM, Gettings KF, Phipps RP, Masel D, Refaai MA, Kirkley SA, Fialkow LB

Transfusion.. 2010 December 50 (12):2738-44. Epub 1900 01 01.

Nuclear emancipation: a platelet tour de force.

Spinelli SL, Maggirwar SB, Blumberg N, Phipps RP

Science signaling.. 2010 October 193 (144):pe37. Epub 10/19/2010.

Aspirin resistance following pediatric cardiac surgery.

Cholette JM, Mamikonian L, Alfieris GM, Blumberg N, Lerner NB

Thrombosis research.. 2010 September 126 (3):200-6. Epub 06/13/2010.

Outcomes after platelet transfusion in patients with heparin-induced thrombocytopenia.

Refaai MA, Chuang C, Menegus M, Blumberg N, Francis CW

Journal of thrombosis and haemostasis : JTH.. 2010 June 8 (6):1419-21. Epub 03/19/2010.

Platelets and megakaryocytes contain functional nuclear factor-kappaB.

Spinelli SL, Casey AE, Pollock SJ, Gertz JM, McMillan DH, Narasipura SD, Mody NA, King MR, Maggirwar SB, Francis CW, Taubman MB, Blumberg N, Phipps RP

Arteriosclerosis, thrombosis, and vascular biology.. 2010 March 30 (3):591-8. Epub 12/30/2009.

Leukoreduction of blood transfusions--there is such a thing as a free lunch.

Blumberg N, Sime PJ, Phipps RP

Critical care medicine.. 2010 February 38 (2):720-1. Epub 1900 01 01.

Platelet transfusions: trigger, dose, benefits, and risks.

Blumberg N, Heal JM, Phillips GL

F1000 medicine reports. 2010 January 272 :5. Epub 01/27/2010.

The platelet as an immune cell-CD40 ligand and transfusion immunomodulation.

Blumberg N, Spinelli SL, Francis CW, Taubman MB, Phipps RP

Immunologic research.. 2009 December 45 (2-3):251-60. Epub 01/29/2009.

Foxp3 regulates megakaryopoiesis and platelet function.

Bernard JJ, Seweryniak KE, Koniski AD, Spinelli SL, Blumberg N, Francis CW, Taubman MB, Palis J, Phipps RP

Arteriosclerosis, thrombosis, and vascular biology.. 2009 November 29 (11):1874-82. Epub 08/06/2009.

Hospital variation in transfusion and infection after cardiac surgery: a cohort study.

Rogers MA, Blumberg N, Saint S, Langa KM, Nallamothu BK

BMC medicine.. 2009 July 317 :37. Epub 07/31/2009.

Lack of significant de novo HLA allosensitization in ventricular assist device recipients transfused with leukoreduced, ABO identical blood products.

Coppage M, Baker M, Fialkow L, Meehan D, Gettings K, Chen L, Massey HT, Blumberg N

Human immunology.. 2009 June 70 (6):413-6. Epub 03/09/2009.

One big unhappy family: transfusion alloimmunization, thrombosis, and immune modulation/inflammation.

Heal JM, Phipps RP, Blumberg N

Transfusion.. 2009 June 49 (6):1032-6. Epub 1900 01 01.

Platelet proteome changes associated with diabetes and during platelet storage for transfusion.

Springer D, Miller J, Spinelli S, Pasa-Tolic L, Purvine S, Daly D, Zangar R, Jin S, Blumberg N, Francis C, Taubman M, Casey A, Wittlin S, Phipps R

Journal of proteome research.. 2009 May 8 (5):2261-72. Epub 1900 01 01.

Statin islands and PPAR ligands in platelets.

Phipps RP, Blumberg N

Arteriosclerosis, thrombosis, and vascular biology.. 2009 May 29 (5):620-1. Epub 1900 01 01.

Impact of ABO mismatching on the outcomes of allogeneic related and unrelated blood and marrow stem cell transplantations for hematologic malignancies: IPD-based meta-analysis of cohort studies.

Kanda J, Ichinohe T, Matsuo K, Benjamin RJ, Klumpp TR, Rozman P, Blumberg N, Mehta J, Sohn SK, Uchiyama T

Transfusion.. 2009 April 49 (4):624-35. Epub 01/02/2009.

15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis.

O'Brien JJ, Baglole CJ, Garcia-Bates TM, Blumberg N, Francis CW, Phipps RP

Journal of thrombosis and haemostasis : JTH.. 2009 January 7 (1):182-9. Epub 10/10/2008.

Blood transfusions, thrombosis, and mortality in hospitalized patients with cancer.

Khorana AA, Francis CW, Blumberg N, Culakova E, Refaai MA, Lyman GH

Archives of internal medicine.. 2008 November 24168 (21):2377-81. Epub 1900 01 01.

15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes.

O'Brien JJ, Spinelli SL, Tober J, Blumberg N, Francis CW, Taubman MB, Palis J, Seweryniak KE, Gertz JM, Phipps RP

Blood.. 2008 November 15112 (10):4051-60. Epub 08/28/2008.

Transfusion recipient epidemiology and outcomes research: possibilities for the future.

Hillyer CD, Blumberg N, Glynn SA, Ness PM,

Transfusion.. 2008 August 48 (8):1530-7. Epub 06/28/2008.

Platelet transfusion and survival in adults with acute leukemia.

Blumberg N, Heal JM, Liesveld JL, Phillips GL, Rowe JM

Leukemia.. 2008 March 22 (3):631-5. Epub 09/06/2007.

Developmental changes in soluble CD40 ligand.

Cholette JM, Blumberg N, Phipps RP, McDermott MP, Gettings KF, Lerner NB

The Journal of pediatrics.. 2008 January 152 (1):50-4, 54.e1. Epub 10/24/2007.

Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.

Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP

Thrombosis and haemostasis.. 2008 January 99 (1):86-95. Epub 1900 01 01.

The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects.

Spinelli SL, O'Brien JJ, Bancos S, Lehmann GM, Springer DL, Blumberg N, Francis CW, Taubman MB, Phipps RP

PPAR research. 2008 2008 :328172. Epub 1900 01 01.

Increased risk of infection and mortality in women after cardiac surgery related to allogeneic blood transfusion.

Rogers MA, Blumberg N, Heal JM, Hicks GL

Journal of women's health.. 2007 December 16 (10):1412-20. Epub 1900 01 01.

Universal leukocyte reduction of blood transfusions.

Blumberg N, Heal JM

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2007 October 1545 (8):1014-5. Epub 09/06/2007.

The intention-to-treat principle in clinical trials and meta-analyses of leukoreduced blood transfusions in surgical patients.

Blumberg N, Zhao H, Wang H, Messing S, Heal JM, Lyman GH

Transfusion.. 2007 April 47 (4):573-81. Epub 1900 01 01.

Release of biologically active CD154 during collection and storage of platelet concentrates prepared for transfusion.

Kaufman J, Spinelli SL, Schultz E, Blumberg N, Phipps RP

Journal of thrombosis and haemostasis : JTH.. 2007 April 5 (4):788-96. Epub 1900 01 01.

The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARgamma ligands.

O'Brien JJ, Ray DM, Spinelli SL, Blumberg N, Taubman MB, Francis CW, Wittlin SD, Phipps RP

Prostaglandins & other lipid mediators.. 2007 January 82 (1-4):68-76. Epub 07/10/2006.

Rogers MAM.; Blumberg N.; Saint S.; Kim C.; Nallamothu BK.; Langa, KM.

Allogeneic

Allogeneic blood transfusions explain increased mortality in women after coronary artery bypass graft surgery.

Rogers MA, Blumberg N, Saint SK, Kim C, Nallamothu BK, Langa KM

American heart journal.. 2006 December 152 (6):1028-34. Epub 1900 01 01.

Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.

Khan SY, Kelher MR, Heal JM, Blumberg N, Boshkov LK, Phipps R, Gettings KF, McLaughlin NJ, Silliman CC

Blood.. 2006 October 1108 (7):2455-62. Epub 06/13/2006.

An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions.

Blumberg N, Gettings KF, Turner C, Heal JM, Phipps RP

Transfusion.. 2006 October 46 (10):1813-21. Epub 1900 01 01.

Soluble CD40 ligand accumulates in stored blood

International Forum: Haemovigilance.

Blumberg N.

Vox Sanguinis. 2006; 90: 237-39.

Platelets as a novel target for PPARgamma ligands : implications for inflammation, diabetes, and cardiovascular disease.

Ray DM, Spinelli SL, O'Brien JJ, Blumberg N, Phipps RP

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.. 2006 20 (4):231-41. Epub 1900 01 01.

What would Karl Landsteiner do? The ABO blood group and stem cell transplantation.

Heal JM, Liesveld JL, Phillips GL, Blumberg N

Bone marrow transplantation.. 2005 November 36 (9):747-55. Epub 1900 01 01.

Decreased sepsis related to indwelling venous access devices coincident with implementation of universal leukoreduction of blood transfusions.

Blumberg N, Fine L, Gettings KF, Heal JM

Transfusion.. 2005 October 45 (10):1632-9. Epub 1900 01 01.

Deleterious clinical effects of transfusion immunomodulation: proven beyond a reasonable doubt.

Blumberg N

Transfusion.. 2005 August 45 (2 Suppl):33S-39S; discussion 39S-40S. Epub 1900 01 01.

International Forum, Transfusion of apheresis platelets and ABO blood groups.

Heal JM.; Blumberg N.

Vox Sanguinis. 2005; 88: 220-221.

Deleterious clinical effects of transfusion immunomodulationproven beyond a reasonable doubt.

Blumberg N.

Transfusion. 2005; 45: [Supplement]: 33S-40S.

A randomized trial of washed red blood cell and platelet transfusions in adult acute leukemia [ISRCTN76536440].

Blumberg N, Heal JM, Rowe JM

BMC blood disorders. 2004 December 104 (1):6. Epub 12/10/2004.

Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes.

Akbiyik F, Ray DM, Gettings KF, Blumberg N, Francis CW, Phipps RP

Blood.. 2004 September 1104 (5):1361-8. Epub 05/06/2004.

Optimizing platelet transfusion therapy.

Heal JM, Blumberg N

Blood reviews.. 2004 September 18 (3):149-65. Epub 1900 01 01.

Erythropoietin to treat anaemia in patients with head and neck cancer.

Blumberg N, Heal JM

Lancet.. 2004 January 3363 (9402):80-1; author reply 81-2. Epub 1900 01 01.

Blumberg N.; Heal JM and Rowe JM.

A randomized trial of washed red blood cells and

Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes.

Koumas L, Smith TJ, Feldon S, Blumberg N, Phipps RP

The American journal of pathology.. 2003 October 163 (4):1291-300. Epub 1900 01 01.

WBC reduction of RBC transfusions is associated with a decreased incidence of RBC alloimmunization.

Blumberg N, Heal JM, Gettings KF

Transfusion.. 2003 July 43 (7):945-52. Epub 1900 01 01.

ABO incompatibility between donor and recipient and clinical outcomes in allogeneic stem cell transplantation.

Goldman J, Liesveld J, Nichols D, Heal J, Blumberg N

Leukemia research.. 2003 June 27 (6):489-91. Epub 1900 01 01.

The causes and treatment of reactions to platelet transfusions.

Blumberg N, Phipps RP, Kaufman J, Heal JM

Transfusion.. 2003 February 43 (2):291-2; author reply 292. Epub 1900 01 01.

Koumas L.; Smith TJ.; Feldon S.; Blumberg N.; Phipps RP.

Thy-1 expression in human

ABO-mismatched platelet transfusions and clinical outcomes after cardiac surgery.

Blumberg N, Heal JM

Transfusion.. 2002 November 42 (11):1527-8; author reply 1528-9. Epub 1900 01 01.

Leukocyte-reduced transfusions in cardiac surgery results of an implementation trial.

Blumberg N, Heal JM, Cowles JW, Hicks GL, Risher WH, Samuel PK, Kirkley SA

American journal of clinical pathology.. 2002 September 118 (3):376-81. Epub 1900 01 01.

Autologous transfusion.

Vanderlinde ES, Heal JM, Blumberg N

BMJ : British medical journal. 2002 March 30324 (7340):772-5. Epub 1900 01 01.

Autologous transfusion.

Vanderlinde E.; Heal JM.; Blumberg N.

British Medical

WBC-reduced blood transfusions and clinical outcome in children with acute lymphoid leukemia.

Rios JA, Korones DN, Heal JM, Blumberg N

Transfusion.. 2001 July 41 (7):873-7. Epub 1900 01 01.

Platelet derived CD154 (CD40 ligand) and febrile responses to transfusion.

Phipps RP, Kaufman J, Blumberg N

Lancet.. 2001 June 23357 (9273):2023-4. Epub 1900 01 01.

Association of ABO-mismatched platelet transfusions with morbidity and mortality in cardiac surgery.

Blumberg N, Heal JM, Hicks GL, Risher WH

Transfusion.. 2001 June 41 (6):790-3. Epub 1900 01 01.

Posttransfusion purpura secondary to an alloantibody reactive with HPA-5a (Br(b)).

Anolik JH, Blumberg N, Snider J, Francis CW

Transfusion.. 2001 May 41 (5):633-6. Epub 1900 01 01.

Platelet washing to prevent recurrent febrile reactions to leucocyte-reduced transfusions.

Vo TD, Cowles J, Heal JM, Blumberg N

Transfusion medicine.. 2001 February 11 (1):45-7. Epub 1900 01 01.

Transfusion-induced immunomodulation: an overview.

Blumberg, N.

Transfusion Medicine Reviews. 2001; 15: 110-112.

Mortality risks, costs and decision making in transfusion medicine.

Blumberg N.; Heal JM.

Amer J Clin Path. 2001; 115: 935-36.

Universal WBC reduction and patient advocacy.

Goldfinger D, Klapper E, Pepkowitz SH, Millar SI, Heal JM, Blumberg N, Wuest D, Reich L, Mayer K

Transfusion.. 2000 December 40 (12):1545-6. Epub 1900 01 01.

Mortality risks, costs, and decision making in transfusion medicine.

Blumberg N, Heal JM

American journal of clinical pathology.. 2000 December 114 (6):934-7. Epub 1900 01 01.

The costs and consequences of management fads and politically driven regulatory oversight.

Blumberg N

Archives of pathology & laboratory medicine.. 1999 July 123 (7):580-4. Epub 1900 01 01.

The second century of ABO: and now for something completely different.

Heal JM, Blumberg N

Transfusion.. 1999 39 (11-12):1155-9. Epub 1900 01 01.

Recombinant erythropoietin and blood transfusions in cancer chemotherapy-induced anemia.

Griggs JJ, Blumberg N

Anti-cancer drugs.. 1998 November 9 (10):925-32. Epub 1900 01 01.

Blood transfusion and total joint replacement surgery: T helper 2 (TH2) cytokine secretion and clinical outcome.

Kirkley SA, Cowles J, Pellegrini VD, Harris CM, Boyd AD, Blumberg N

Transfusion medicine.. 1998 September 8 (3):195-204. Epub 1900 01 01.

Anesthesiology.

Blumberg N

The New England journal of medicine.. 1998 March 5338 (10):686; author reply 686-7. Epub 1900 01 01.

Blood transfusion immunomodulation: the silent epidemic.

Blumberg N, Heal JM

Archives of pathology & laboratory medicine.. 1998 February 122 (2):117-9. Epub 1900 01 01.

Allogeneic transfusion and infection: economic and clinical implications.

Blumberg N

Seminars in hematology.. 1997 July 34 (3 Suppl 2):34-40. Epub 1900 01 01.

The transfusion immunomodulation theory: the Th1/Th2 paradigm and an analogy with pregnancy as a unifying mechanism.

Blumberg N, Heal JM

Seminars in hematology.. 1996 October 33 (4):329-40. Epub 1900 01 01.

Immunomodulation by blood transfusion: an evolving scientific and clinical challenge.

Blumberg N, Heal JM

The American journal of medicine.. 1996 September 101 (3):299-308. Epub 1900 01 01.

Immunological tolerance.

Blumberg N, Heal JM

Science.. 1996 June 7272 (5267):1408. Epub 1900 01 01.

Immunological tolerance.

Blumberg N, Heal JM

Science.. 1996 June 7272 (5267):1408b. Epub 1900 01 01.

A cost analysis of autologous and allogeneic transfusions in hip-replacement surgery.

Blumberg N, Kirkley SA, Heal JM

American journal of surgery.. 1996 March 171 (3):324-30. Epub 1900 01 01.

The transfusion immunomodulation theory--the Th1/Th2 paradigm and an analogy with pregnancy as a unifying mechanism.

Blumberg N.; Heal JM.

Sem Hematology. 1996; 33: 329-340.

Interaction of platelet fc and complement receptors with circulating immune complexes involving the AB0 system.

Heal JM, Masel D, Blumberg N

Vox sanguinis.. 1996 71 (4):205-11. Epub 1900 01 01.

Current research on the immunomodulatory effect of allogeneic blood transfusion.

Dzik S, Blajchman MA, Blumberg N, Kirkley SA, Heal JM, Wood K

Vox sanguinis.. 1996 70 (4):187-94. Epub 1900 01 01.

Noncausal relationship between cancer recurrence and perioperative blood transfusions.

Blumberg N, Heal JM

Annals of surgery.. 1995 December 222 (6):757-8. Epub 1900 01 01.

Transfusion and the immune system: a paradigm shift in progress?

Blumberg N, Heal JM

Transfusion.. 1995 October 35 (10):879-83. Epub 1900 01 01.

Cytokine secretion after allogeneic or autologous blood transfusion.

Kirkley SA, Cowles J, Pellegrini VD, Harris CM, Boyd AD, Blumberg N

Lancet.. 1995 February 25345 (8948):527. Epub 1900 01 01.

Leukodepleted-ABO-identical blood components in the treatment of hematologic malignancies: a cost analysis.

Blumberg N, Heal JM, Kirkley SA, DiPersio JF, Rapoport AP, Rowe JM

American journal of hematology.. 1995 February 48 (2):108-15. Epub 1900 01 01.

FilteredABOidentical blood components in the treatment of haematologic malignanciesa cost analysis.

Blumberg N.; Heal JM.; Kirkley SA.; DiPersio JF.; Rapoport.; AP.; Rowe JM.

Amer J Hematol. 1995; 48: 108-115.

Cytokine secretion after allogeneic or autologous blood transfusions.

Kirkley SA.; Cowles J.; Pellegrini, VD, Jr.; Harris CM.; Boyd AD.; Blumberg N.

The Lancet. 1995; 345: 527.

Leukocyte-reduced transfusions of ABO-identical platelets and clinical outcome in autologous bone marrow transplantation for lymphoma.

Heal JM, Blumberg N, Kirkley SA, DiPersio JF, Rapoport AP, Rowe JM

Bone marrow transplantation.. 1994 December 14 (6):943-8. Epub 1900 01 01.

Use of single donor platelets.

Kirkley SA, Blumberg N

Blood reviews.. 1994 September 8 (3):142-7. Epub 1900 01 01.

Perioperative blood transfusion and colorectal cancer recurrence.

Blumberg N, Heal JM

Transfusion.. 1994 May 34 (5):450-2. Epub 1900 01 01.

Effects of transfusion on immune function. Cancer recurrence and infection.

Blumberg N, Heal JM

Archives of pathology & laboratory medicine.. 1994 April 118 (4):371-9. Epub 1900 01 01.

A possible survival advantage in adults with acute leukemia receiving ABO-identical platelet transfusions.

Heal JM, Kenmotsu N, Rowe JM, Blumberg N

American journal of hematology.. 1994 February 45 (2):189-90. Epub 1900 01 01.

Heal JM.; Kenmotsu N.; Rowe JM.; Blumberg N.

A possible survival advantage in

Circulating immune complexes involving the ABO system after platelet transfusion.

Heal JM, Masel D, Rowe JM, Blumberg N

British journal of haematology.. 1993 November 85 (3):566-72. Epub 1900 01 01.

Blood transfusions and prognosis in colorectal cancer.

Blumberg N, Heal JM

The New England journal of medicine.. 1993 October 28329 (18):1355; author reply 1355-6. Epub 1900 01 01.

ABO and platelet transfusion revisited.

Heal JM, Rowe JM, Blumberg N

Annals of hematology.. 1993 June 66 (6):309-14. Epub 1900 01 01.

Pathologists are doctors.

Blumberg N, Albert M, Krabill K

Annals of internal medicine.. 1993 April 1118 (7):575. Epub 1900 01 01.

The role of ABO matching in platelet transfusion.

Heal JM, Rowe JM, McMican A, Masel D, Finke C, Blumberg N

European journal of haematology.. 1993 February 50 (2):110-7. Epub 1900 01 01.

The role of ABO matching in platelet transfusion.

Heal JM.; Rowe JM.; McMican A.; Masel D.; Finke C.; Blumberg N.

Eur. J. Haemat. 1993; 50: 110-117.

Circulating immune complexes involving the ABO system in patients refractory to platelet transfusion.

Heal JM.; Masel D.; Rowe JM.; Blumberg N.

Brit J Haematol. 1993; 85: 566-572.

Homologous blood transfusion as a risk factor for postoperative infection after coronary artery bypass graft operations.

Murphy PJ, Connery C, Hicks GL, Blumberg N

The Journal of thoracic and cardiovascular surgery.. 1992 October 104 (4):1092-9. Epub 1900 01 01.

White cell reduction, ultraviolet irradiation, and platelet refractoriness in acute myeloid leukemia.

Blumberg N, Heal JM

Transfusion.. 1992 September 32 (7):688-9. Epub 1900 01 01.

Antibodies to plasma proteins: an association with platelet transfusion refractoriness.

Heal JM, Cowles J, Masel D, Rowe JM, Blumberg N

British journal of haematology.. 1992 January 80 (1):83-90. Epub 1900 01 01.

Heal JM.; Cowles J.; Masel D.; Rowe JM.; Blumberg N.

Antibodies to plasma

Murphy P.; Connery C.; Hicks GL.; Blumberg N.

Homologous blood transfusion as a risk factor for postoperative infection after coronary artery

An apparent primary immune response involving anti-Jka and anti-P1 detected 10 days after transfusion.

Cox MT, Roberts M, LaJoie J, Enfonde M, Kress D, Blumberg N

Transfusion.. 1992 32 (9):874. Epub 1900 01 01.

A clinical and immunologic study of blood transfusion and postoperative bacterial infection in spinal surgery.

Triulzi DJ, Vanek K, Ryan DH, Blumberg N

Transfusion.. 1992 32 (6):517-24. Epub 1900 01 01.

Malignant melanoma: primary presentation in bone marrow and lymph node.

Basile M, Moskowitz B, Harris J, Blumberg N, Bennett JM

Medical and pediatric oncology.. 1992 20 (1):75-7. Epub 1900 01 01.

Severe fetal hydrops resulting from ABO incompatibility.

Sherer DM, Abramowicz JS, Ryan RM, Sheils LA, Blumberg N, Woods JR

Obstetrics and gynecology.. 1991 November 78 (5 Pt 2):897-9. Epub 1900 01 01.

Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions.

Murphy P, Heal JM, Blumberg N

Transfusion.. 1991 31 (3):212-7. Epub 1900 01 01.

Transfusion-induced immunomodulation and its clinical consequences.

Blumberg N, Triulzi DJ, Heal JM

Transfusion medicine reviews.. 1990 October 4 (4 Suppl 1):24-35. Epub 1900 01 01.

The relationship of blood transfusion, tumor staging, and cancer recurrence.

Blumberg N, Chuang-Stein C, Heal JM

Transfusion.. 1990 May 30 (4):291-4. Epub 1900 01 01.

Variability in response to cryoprecipitate therapy in uremia.

Triulzi D.; Blumberg N.

Yale J Biology Med. 1990; 63: 1-7.

Transfusion as a predisposing factor for cancer recurrence and perioperative bacterial infection.

Blumberg N.; Heal JM.

Yale J Biology Med. 1990; 63: 429-434.

Association of transfusion with postoperative bacterial infection.

Triulzi DJ, Blumberg N, Heal JM

Critical reviews in clinical laboratory sciences.. 1990 28 (2):95-107. Epub 1900 01 01.

Variability in response to cryoprecipitate treatment for hemostatic defects in uremia.

Triulzi DJ, Blumberg N

The Yale journal of biology and medicine.. 1990 63 (1):1-7. Epub 1900 01 01.

Beyond ABO and D antigen matching: how far and for whom?

Blumberg N

Transfusion.. 1990 30 (6):482-4. Epub 1900 01 01.

Transfusion-induced immunomodulation and its possible role in cancer recurrence and perioperative bacterial infection.

Blumberg N, Heal JM

The Yale journal of biology and medicine.. 1990 63 (5):429-33. Epub 1900 01 01.

Transfusion and recipient immune function.

Blumberg N, Heal JM

Archives of pathology & laboratory medicine.. 1989 March 113 (3):246-53. Epub 1900 01 01.

Transfusion and host defenses against cancer recurrence and infection.

Blumberg N, Heal JM

Transfusion.. 1989 29 (3):236-45. Epub 1900 01 01.

The fine specificity of Lewis blood group antibodies. Evidence for maturation of the immune response.

Cowles JW, Spitalnik SL, Blumberg N

Vox sanguinis.. 1989 56 (2):107-11. Epub 1900 01 01.

The importance of ABH antigens in platelet crossmatching.

Heal JM, Mullin A, Blumberg N

Transfusion.. 1989 29 (6):514-20. Epub 1900 01 01.

Perioperative blood transfusions and prostate cancer recurrence and survival.

Heal JM, Chuang C, Blumberg N

American journal of surgery.. 1988 November 156 (5):374-80. Epub 1900 01 01.

Renal allograft survival in transfused and non-transfused patients.

Blumberg N, Heal J

Lancet.. 1988 April 231 (8591):946. Epub 1900 01 01.

Further evidence supporting a cause and effect relationship between blood transfusion and earlier cancer recurrence.

Blumberg N, Heal J, Chuang C, Murphy P, Agarwal M

Annals of surgery.. 1988 April 207 (4):410-5. Epub 1900 01 01.

Blumberg N.; Heal JM.

Evidence for plasma-mediated immunomodulation--transfusions of red cells are associated with a lower risk of

Corsetti JP.; Sotirchos SV.; Cox C.; Cowles JW.; Leary JF.; Blumberg N.

The correction of cellular autofluorescence in flow cytometry by mathematical

Blumberg N.

The fate of cells of the immune system during blood storage

A possible association between survival time and transfusion in cervical cancer.

Blumberg N, Agarwal MM, Chuang C

The Yale journal of biology and medicine.. 1988 61 (6):493-500. Epub 1900 01 01.

A rapid and accurate single-drop modification of the acid-elution technique for detecting fetomaternal hemorrhage.

Corsetti JP, Cowles JW, Cox MT, Blumberg N

Vox sanguinis.. 1988 54 (1):39-42. Epub 1900 01 01.

A chloroquine elution technique for platelet serology.

Masel DS, Blumberg N, Heal JM

Transfusion.. 1988 28 (2):132-6. Epub 1900 01 01.

Clinical correlates in patients with elevated platelet-associated immunoglobulins.

Szal M, Blumberg N

Annals of clinical and laboratory science.. 1988 18 (1):24-33. Epub 1900 01 01.

Perioperative blood transfusion and solid tumour recurrence.

Blumberg N, Heal JM

Blood reviews.. 1987 December 1 (4):219-29. Epub 1900 01 01.

An evaluation of crossmatching, HLA, and ABO matching for platelet transfusions to refractory patients.

Heal JM, Blumberg N, Masel D

Blood.. 1987 July 70 (1):23-30. Epub 1900 01 01.

Single-unit blood transfusion: doubtful dogma defeated.

Cass RM, Blumberg N

JAMA.. 1987 February 6257 (5):628-9. Epub 1900 01 01.

Comparison of quantitative acid-elution technique and flow cytometry for detecting fetomaternal hemorrhage.

Corsetti JP, Cox C, Leary JF, Cox MT, Blumberg N, Doherty RA

Annals of clinical and laboratory science.. 1987 17 (3):197-206. Epub 1900 01 01.

Neutralization of P blood group antibodies by synthetic solid-phase antigens.

Cowles JW, Blumberg N

Transfusion.. 1987 27 (3):272-5. Epub 1900 01 01.

Perioperative blood transfusion and solid tumor recurrence--a review.

Blumberg N, Heal JM

Cancer investigation.. 1987 5 (6):615-25. Epub 1900 01 01.

Comparison of monoclonal antisera with conventional antisera for Lewis blood group antigen determination.

Cowles JW, Cox MT, McMican A, Blumberg N

Vox sanguinis.. 1987 52 (1-2):83-4. Epub 1900 01 01.

Association between transfusion of whole blood and recurrence of cancer.

Blumberg N, Heal JM, Murphy P, Agarwal MM, Chuang C

British medical journal.. 1986 August 30293 (6546):530-3. Epub 1900 01 01.

Disparities in estimates of IgG bound to normal platelets.

Blumberg N, Masel D, Stoler M

Blood.. 1986 January 67 (1):200-2. Epub 1900 01 01.

Association between transfusion of whole blood and cancer recurrence.

Blumberg N.; Heal J.; Murphy P.; Agarwal M.; Chuang C.

British Medical J. 1986; 293: 530-533.

Detection of anti-Lea in Le(a-b+) individuals by kinetic ELISA.

Cowles JW, Spitalnik SL, Blumberg N

Vox sanguinis.. 1986 50 (3):164-8. Epub 1900 01 01.

A critical survey of fresh-frozen plasma use.

Blumberg N, Laczin J, McMican A, Heal J, Arvan D

Transfusion.. 1986 26 (6):511-3. Epub 1900 01 01.

Relation between recurrence of cancer of the colon and blood transfusion.

Blumberg N, Agarwal MM, Chuang C

British medical journal.. 1985 April 6290 (6474):1037-9. Epub 1900 01 01.

Relation between recurrence of cancer of the colon and blood transfusion.

Blumberg N.; Agarwal M.; Chuang C.

British Medical J. 1985; 290: 1037-1039.

Detection of IgG anti-Lewis (a) antibodies in cord sera by kinetic Elisa.

Spitalnik S, Cowles J, Cox MT, Blumberg N

Vox sanguinis.. 1985 48 (4):235-8. Epub 1900 01 01.

Correlation of humoral immunity to Lewis blood group antigens with renal transplant rejection.

Spitalnik S, Pfaff W, Cowles J, Ireland JE, Scornik JC, Blumberg N

Transplantation.. 1984 March 37 (3):265-8. Epub 1900 01 01.

Removal of HLA-A,B antigens from platelets.

Blumberg N, Masel D, Mayer T, Horan P, Heal J

Blood.. 1984 February 63 (2):448-50. Epub 1900 01 01.

A case report of a neonate with an unexpected second antibody, anti-Jk(b).

Cox MT.; McMican A.; Blumberg N.

J. Med. Technology. 1984; 1: 225-226.

Should chronic transfusions be matched for antigens other than ABO and Rho(D)?

Blumberg N, Ross K, Avila E, Peck K

Vox sanguinis.. 1984 47 (3):205-8. Epub 1900 01 01.

Red-cell alloantibody response in AIDS.

Ramsey G, Stoler M, Blumberg N

Lancet.. 1983 September 32 (8349):575. Epub 1900 01 01.

Neutralization of Lewis blood group antibodies by synthetic immunoadsorbents.

Spitalnik SL, Cowles JW, Cox MT, Blumberg N

American journal of clinical pathology.. 1983 July 80 (1):63-5. Epub 1900 01 01.

Rh sensitization.

Blumberg N, McMican A, Heal J

Obstetrics and gynecology.. 1983 July 62 (1):135-6. Epub 1900 01 01.

Do preoperative laboratory tests predict blood transfusion needs in cardiac operations?

Ramsey G, Arvan DA, Stewart S, Blumberg N

The Journal of thoracic and cardiovascular surgery.. 1983 April 85 (4):564-9. Epub 1900 01 01.

Do preoperative laboratory tests predict blood transfusion needs in cardiac surgery?

Ramsey G.; Arvan DA.; Stewart S.; Blumberg N.

J. Thoracic Cardiovas. Surg. 1983; 85: 564-569.

The type and screen--are patient charges a valid measure of cost reduction?

Ramsey G.; Desley C.; Ross K.; Peck K.; Spennachio J.; Blumberg N.

Ann. Clin. Lab. Science. 1983; 13: 55-58.

Neutralization of Lewis blood group antibodies by synthetic immunoadsorbents.

Spitalnik S.; Cowles J.; Cox MT.; Blumberg N.

Amer. J. Clin. Path. 1983; 80: 63-65.

Red cell alloantibody response in AIDS.

Ramsey G.; Stoler M.; Blumberg N.

Lancet ii:. 1983; : 575.

A technetium-99m red cell survival technique for in vivo compatibility testing.

Holt JT, Spitalnik SL, McMican AE, Wilson G, Blumberg N

Transfusion.. 1983 23 (2):148-51. Epub 1900 01 01.

A new technique in quantitative immunohematology: solid-phase kinetic enzyme-linked immunosorbent assay.

Spitalnik S, Cowles J, Cox MT, Baker D, Holt J, Blumberg N

Vox sanguinis.. 1983 45 (6):440-8. Epub 1900 01 01.

The type and screen: are patient charges a valid measure of cost reduction?

Ramsey G, Desley C, Ross K, Peck K, Spennachio J, Blumberg N

Annals of clinical and laboratory science.. 1983 13 (1):55-8. Epub 1900 01 01.

Immune response to chronic red blood cell transfusion.

Blumberg N, Peck K, Ross K, Avila E

Vox sanguinis.. 1983 44 (4):212-7. Epub 1900 01 01.

Successful cardiac bypass surgery in the presence of a potent cold agglutinin without plasma exchange.

Blumberg N, Hicks G, Woll J, Nusbacher J, Cox MT, Wilbur D, Schwedfeger D, McMican A

Transfusion.. 1983 23 (4):363. Epub 1900 01 01.

Treatment of thrombotic thrombocytopenic purpura. Evaluation of plasma exchange and review of the literature.

Pisciotto P, Rosen D, Silver H, Genco P, Blumberg N, Katz AJ, Morse EE

Vox sanguinis.. 1983 45 (3):185-96. Epub 1900 01 01.

Case report of an anti-Jk b persisting for sixteen years.

Cox MT, McMican A, Blumberg N

Transfusion.. 1983 23 (4):362. Epub 1900 01 01.

Passive acquisition of new HLA phenotypes by human platelets incubated in plasma.

Blumberg N, Masel D, Mayer T, Horan P, Heal J

Blood.. 1982 July 60 (1):276. Epub 1900 01 01.

Evaluation of individuals deferred from blood donation for medical reasons.

Blumberg N, Shah I, Hoagland J, Shirer L, Katz AJ

Vox sanguinis.. 1982 January 42 (1):1-7. Epub 1900 01 01.

An analysis of two types of granulocyte transfusions in patients with acute leukemia and septicemia. :

Morse EE.; Snyder E.; Blumberg N.; Katz AJ.

Ann. Clin. Lab. Science. 1982; 12: 106-110.

Acquisition by human platelets of new HLA-A,B phenotypes from plasma.

Blumberg N.; Masel D.; Mayer T.; Horan P.; Heal J.

Blood. 1982; 60:: 275.

Analysis of two types of granulocyte transfusions in patients with acute leukemia and septicemia.

Morse EE, Synder E, Blumberg N, Katz AJ

Annals of clinical and laboratory science.. 1982 12 (2):106-10. Epub 1900 01 01.

Granulocyte yields using the Haemonetics 30. Effects of variations in corticosteroid regimen and donor selection.

Blumberg N, Shah I, Katz AJ, Morse EE

Vox sanguinis.. 1982 42 (5):225-32. Epub 1900 01 01.

Incidence of adverse reactions in blood donors taking antihypertensive medications.

Pisciotto P, Sataro P, Blumberg N

Transfusion.. 1982 22 (6):530-1. Epub 1900 01 01.

A new approach to washing red blood cells frozen with a high concentration of glycerol in a special freezing container.

Kurtz SR, Valeri DA, Gray A, Lindberg JR, McMican A, Blumberg N, Valeri CR

Vox sanguinis.. 1982 43 (3):132-7. Epub 1900 01 01.

The serology of Sda effects of transfusion and pregnancy.

Spitalnik S, Cox MT, Spennacchio J, Guenther R, Blumberg N

Vox sanguinis.. 1982 42 (6):308-12. Epub 1900 01 01.

Therapeutic plasmapheresis and cytapheresis. A review.

Blumberg N, Katz AJ

Connecticut medicine.. 1981 February 45 (2):85-90. Epub 1900 01 01.

Platelet collection and transfusion using the fenwal CS-3000 cell separator.

Katz AJ, Genco PV, Blumberg N, Snyder EL, Camp B, Morse EE

Transfusion.. 1981 21 (5):560-3. Epub 1900 01 01.

Long-term granulocyte transfusion in patients with malignant neoplasms.

Buchholz DH, Blumberg N, Bove JR

Archives of internal medicine.. 1979 March 139 (3):317-20. Epub 1900 01 01.

Meeting therapeutic pheresis needs in the region.

Katz AJ.; Blumberg N.; King C.

Proceedings of the First Annual Apheresis Symposium: Current Concepts and Future Trends. 1979; : 176-191.

Un-cross-matched blood for emergency transfusion. One year's experience in a civilian setting.

Blumberg N, Bove JR

JAMA.. 1978 November 3240 (19):2057-9. Epub 1900 01 01.

Collection of granulocytes for transfusion--effect of collection methods on cell enzyme release. Vox

Blumberg N.; Genco PV.; Katz AJ.; Bove JR.

Sanguinis. 1978; 35: 207-214.

Collection of granulocytes for transfusion. The effect of collection methods on cell enzyme release.

Blumberg N, Genco P, Katz A, Bove J

Vox sanguinis.. 1978 35 (4):207-14. Epub 1900 01 01.

Tumor angiogenesis factor. Speculations on an approach to cancer chemotherapy.

Blumberg N

The Yale journal of biology and medicine.. 1974 47 (2):71-81. Epub 1900 01 01.

Release of biologically active CD154 during collection and storage of platelet concentrates prepared for transfusion.

Kaufman J.; Spinelli SL.; Schultz L.; Blumberg N.; Phipps RP.

(submitted, Journal of Thrombosis and Haemostasis).

Peroxisome Proliferator-Activated Receptor g and the Retinoid X Receptor are released from activated human platelets and are shed in platelet microparticles.

Ray DM.; Spinelli SL.; Murant T.; Blumberg N.; Francis CW.; Phipps RP.

submitted. .

Rogers MAM.; Blumberg N.; Heal JM.; Hicks, GL, Jr.

Increased mortality in women after

Developmental changes in soluble CD40 ligand

Chollette JM.; Blumberg N.; Phipps RP.; McDermott MP.; Gettings KF.; Lerner NB.;.

J. Pediatrics. .

Books

Best Practice and Research in Clinical Haematology (2006)

Chapter: Clinical Use of Plasma and Plasma Fractions

Authors: Blumberg, N.; Francis CW.; Heal JM.;

Publisher: Elsevier, UK 2006

Blood Banking and Transfusion Medicine: Basic Principles and Practice (2006)

Chapter: Transfusion immunomodulation

Authors: Blumberg N.; Heal JM.

Publisher: Churchill-Livingstone 2006

Perioperative Transfusion Medicine (2005)

Chapter: Immunomodulation by Transfusion

Authors: Blumberg, N.; Heal JM.

Publisher: Lippincott 2005

The Scientific Basis of Transfusion Medicine (2000)

Chapter: Transfusion Immunomodulation

Authors: Blumberg, N.; Heal JM.

Publisher: WB Saunders 2000

Transfusion Medicine & Alternatives to Blood Transfusion (2000)

Chapter: Immunomodulation and allogeneic transfusion

Authors: Blumberg, N.; Heal JM.; Triulzi DJ.

Publisher: NATA, R&J Editions Medicales, Paris 2000

Transfusion Medicine & Alternatives to Blood Transfusion (2000)

Chapter: Cost effectiveness of allogeneic versus autologous blood use

Authors: Blumberg N.; Heal JM.

Publisher: NATA, R&J Editions Medicales, Paris 2000

Leukemia and Lymphoma Society (2000)

Chapter: Blood Transfusion-a booklet for patients.

Authors: Heal, JM.; Blumberg, N.

Publisher: New York NY 2000

Orthopaedic Knowledge Update (1999)

Chapter: Blood Transfusion

Authors: Blumberg N.; Kirkley SA.

Publisher: American Academy of Orthopaedic Surgeons, Rosemont, IL 1999

Immunomodulatory Effects of Blood Transfusion (1999)

Chapter: History of the Transfusion Immunomodulatory Theory

Authors: Blumberg N.; Heal JM.

Publisher: AABB Press, Bethesda MD 1999

Autotransfusion: Therapeutic Principles and Trends (1997)

Chapter: Increased postoperative infections after allogeneic transfusions.

Authors: Kirkley, SA.; Blumberg N.

Publisher: Appleton, Detroit, MI 1997

Clinical Benefits of Leukodepleted Blood Products (1995)

Chapter: Leukocyte depletion and tranfusion induced immunomodulation.

Authors: Triulzi D.; Blumberg, N.

Publisher: RG Landes, Austin, TX. 1995

The Scientific Basis of Transfusion Medicine (1994)

Chapter: Transfusion associated immunomodulation.

Authors: Blumberg, N.; Heal JM.

Publisher: WB Saunders 1994

Transfusion Medicine (1990)

Chapter: Transfusion induced immunomodulation and its clinical consequences.

Authors: Triulzi DJ.; Heal JM.; Blumberg, N.

Publisher: American Association of Blood Banks, Arlington, VA 1990

Therapeutic Hemapheresis (1990)

Chapter: Partial plasma exchange: diseases in which it is of reported efficacy. A Technical Workshop

Authors: Blumberg, N.; Katz AJ.

Publisher: AABB 1990

Limiting Homologous Exposure: Alternative Strategies (1989)

Chapter: The rationale for limiting recipient exposure to homologous transfusions, and overview.

Authors: Heal JM.; Blumberg N.

Publisher: American Association of Blood Banks, Arlington, VA 1989

Adverse Transfusion Reactions (1986)

Chapter: Professional self-assessment program, immunohematology series.

Authors: Snyder, E.

Publisher: American Ass. of Blood Banks & American Ass. of Clinical Pathologists, Chicago, IL. 1986

Blood Transfusion Therapy-An Audiovisual Program (71 slides/cassette (1985)

Authors: Snyder, E.; Kennedy M.; Blumberg N.

Publisher: American Association of Blood Banks, Arlington, VA 1985

Blood Transfusion Therapy- A Self Assessment Program (1984)

Authors: Snyder e.; Kennedy M.; Blumberg N.

Publisher: American Association of Blood Banks, Arlington, VA 1984

Blood Transfusion Therapy- Patient Management Problems (1984)

Authors: Snyder E.; Kennedy M.; Blumberg N.

Publisher: American Association of Blood Banks, Arlington, VA. 1984

Blood Transfusion Therapy-A Physician's Handbook (1983)

Authors: Snyder E.; Kennedy M.; Blumberg N.

Publisher: American Association of Blood Banks, Arlington, VA. 1983

Blood Component Therapy (1980)

Chapter: Med-Ed Series in Clinical Teachings, MEDCOM Audiovisual program of 66 slides and audiocassette

Authors: Snyder, E.; Blumberg N.

Publisher: MEDCOM, Garden Grove, CA. 1980

Blood transfusion reactions and complications. Clinical Teachings, MEDCOM (1979)

Chapter: Audiovisual program of 52 slides and audiocassette.

Authors: Snyder, E.; Blumberg, N.

Publisher: MEDCOM, Garden Grove, CA. 1979

Actinomycin D- (1975)

Chapter: -a review of its biology and chemotherapeutic properties with a re-evaluation of its use as an antineoplastic agent.

Authors: Blumberg, N.

Publisher: Yale University School of Medicine, Thesis for M.D. degree 1975

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