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Carol Fries Simpson, M.D.

Carol Fries Simpson, M.D.

Pediatrics

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UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
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Contact

Appointment (585) 275-2981
Fax (585) 273-1039

About Me

Dr. Fries’ clinical interests include the evaluation, management, and surveillance of children and adolescents affected by pediatric cancers and blood disorders. She is also an early-career physician/scientist studying the genetic and molecular mechanisms of the most common childhood malignancy, acu...
Dr. Fries’ clinical interests include the evaluation, management, and surveillance of children and adolescents affected by pediatric cancers and blood disorders. She is also an early-career physician/scientist studying the genetic and molecular mechanisms of the most common childhood malignancy, acute lymphoblastic leukemia (ALL). Her ultimate career goal is to improve the personalization of therapy and minimize unnecessary treatment-related toxicity for children and adolescents affected by cancer.

Certified Specialties

Pediatric Hematology-Oncology

Pediatrics - American Board of Pediatrics

Faculty Appointments

Assistant Professor - Department of Pediatrics, Hematology and Oncology (SMD)

Assistant Professor - Department of Pathology and Laboratory Medicine (SMD) - Joint

Credentials

Residency & Fellowship

Fellowship, Pediatric Hematology-Oncology, University of Rochester Medical Center. 2016 - 2019

Residency, Pediatrics, University of Rochester Medical Center. 2015 - 2016

Residency, Pediatrics, University of Rochester Medical Center. 2013 - 2015

Internship, Pediatrics, University of Rochester Medical Center. 2012 - 2013

Internship, General Pediatrics, Golisano Children's Hospital-University of Rochester. 2012 - 2013

Education

MD | SUNY Upstate Medical University College of Medicine. 2012

Awards

Clinical and Translational Science Institute (CTSI) Pilot Studies Trainee Award. 2018 - 2019

Department of Pediatrics Dean's Fellowship. 2017 - 2019

Fellow Teaching Award. 2017 - 2017

House Staff Teaching Award. 2015 - 2015

Rochester General Hospital Chief Roundtable Honor. 2014 - 2015

Excellence in Neonatology Award. 2014 - 2014

Gold Humanism Honor Society. 2012 - 2012

Herbert Lourie, MD Award. 2012 - 2012

John T. Lowry Jr. Prize for the Outstanding Graduate in Biology. 2008 - 2008

Phi Beta Kappa. 2008 - 2008

Phi Sigma Biological Sciences Honor Society. 2008 - 2008

Research

Dr. Fries is an early-career physician/scientist with an interest in translational research efforts to improve the care of children with lymphoid malignancies, particularly acute lymphoblastic leukemia (ALL) and lymphoma. Her ultimate goal is to construct a career niche focused on improving patient ...
Dr. Fries is an early-career physician/scientist with an interest in translational research efforts to improve the care of children with lymphoid malignancies, particularly acute lymphoblastic leukemia (ALL) and lymphoma. Her ultimate goal is to construct a career niche focused on improving patient risk stratification to prevent relapse while minimizing unnecessary treatment toxicity. She has been trained in deep sequencing methods for evaluating genetic variation in lymphoid malignancies, with a particular interest in immunoglobulin sequencing techniques for the study of diverse clonal composition in B cell ALL.

Publications

Journal Articles

High-throughput sequencing of archival cerebrospinal fluid specimens defines B-lymphoblastic leukemia clonal composition.

Foley K, Adlowitz DG, Baker C, Rock PJ, Burack R, Fries C

Pediatric blood & cancer.. 2024 November 71 (11):e31281. Epub 08/21/2024.

How I approach B-lymphoblastic lymphoma in children.

Devine KJ, Fries C, Hermiston M, Wistinghausen B

Pediatric blood & cancer.. 2023 August 70 (8):e30401. Epub 05/09/2023.

Challenging T-ALL to IL-7Rp dual inhibition.

Fries C, Hermiston ML

Blood.. 2023 July 13142 (2):124-126. Epub 1900 01 01.

Prognostic impact of pretreatment immunoglobulin clonal composition in pediatric B-lymphoblastic leukemia.

Fries C, Lee LW, Devidas M, Dai Y, Rabin KR, Gupta S, Loh ML, Kirsch IR, Wood B, Rau RE

Haematologica.. 2023 March 1108 (3):900-904. Epub 03/01/2023.

Allogeneic Bone Marrow Transplant as a Cure for Refractory T-Cell Large Granular Lymphocytic Leukemia in an Adolescent.

Fries C, Evans AG, Cheon H, Korones DN, Loughran TP, Andolina JR

Journal of pediatric hematology/oncology.. 2022 August 144 (6):e960-e963. Epub 12/29/2021.

Successful Bone Marrow Transplantation With Intensive Post-transplant Intrathecal Chemotherapy for CNS Relapsed AML in 2 Infants.

Andolina JR, Fries C, Boulware R, Vargas A, Fraint E, Barth M, Abrusko S, Comito M, Monteleone P

Journal of pediatric hematology/oncology.. 2022 January 144 (1):e264-e267. Epub 1900 01 01.

Migratory Arthralgia in a 3-year-old Girl.

Fries C, Long AM, Marston BA, Andolina JR

Pediatrics in review. 2022 January 143 (1):41-44. Epub 1900 01 01.

Myeloablative Carboplatin and Thiotepa With Autologous Stem Cell Rescue for Nonmedulloblastoma High-risk CNS Tumors in Young Children.

Fries C, Girvin AR, Korones DN, Weintraub L, Fitzpatrick L, Andolina JR

Journal of pediatric hematology/oncology.. 2021 November 143 (8):e1223-e1227. Epub 1900 01 01.

Transplacental transfer of congenital B-cell acute lymphoblastic leukemia to the maternal vasculature.

Fries C, Noronha SA, Metlay L, Zhang B

Pediatric blood & cancer.. 2021 September 68 (9):e29142. Epub 06/14/2021.

Acute lymphoblastic leukemia clonal distribution between bone marrow and peripheral blood.

Fries C, Adlowitz DG, Spence JM, Spence JP, Rock PJ, Burack WR

Pediatric blood & cancer.. 2020 June 67 (6):e28280. Epub 04/11/2020.

An evolving technology for an evolving disease: A commentary on NGS-based MRD evaluation in B-ALL.

Fries C, Burack R

Leukemia research.. 2019 January 76 :105-106. Epub 11/16/2018.

"On the road to a better CAR: Identifying the variables associated with a durable response to CAR-T cell therapy in relapsed/refractory B-ALL."

O'Dwyer K, Fries C.

The Hematologist. 2019; 16(4).

A clinical perspective on immunoglobulin heavy chain clonal heterogeneity in B cell acute lymphoblastic leukemia.

Fries C, Burack WR

Leukemia research.. 2018 December 75 :15-22. Epub 11/03/2018.

Ratings & Comments

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