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Augusto A. Litonjua, M.D., M.P.H.

Augusto A. Litonjua, M.D., M.P.H.

Pediatrics , Pediatric Cystic Fibrosis Center , Pediatric Pulmonology

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UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
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Contact

Office (585) 275-2464
Fax (585) 275-8706

About Me

Dr. Litonjua is interested in the management of asthma patients and how to better prevent asthma exacerbations. As part of this, the use of biologics and specific nutrients hold promise in the treatment of these patients.
Dr. Litonjua is interested in the management of asthma patients and how to better prevent asthma exacerbations. As part of this, the use of biologics and specific nutrients hold promise in the treatment of these patients.

Certified Specialties

Critical Care Medicine

Pulmonary Disease - American Board of Internal Medicine

Faculty Appointments

Professor - Department of Pediatrics, Pulmonology (SMD)

Professor - Department of Medicine, Pulmonary Diseases and Critical Care (SMD) - Joint

Credentials

Residency & Fellowship

Fellowship, Epidemiology, Brigham & Womens Hospital. 1995 - 1997

Fellowship, Pulmonary and Critical Care Medicine, West Virginia University Hospitals. 1992 - 1995

Residency, Internal Medicine, Brooklyn Hospital Center-Downtown Campus. 1989 - 1992

Internship, Internal Medicine, Brooklyn Hospital Center-Downtown Campus. 1988 - 1989

Internship, Philippine General Hospital (Philippines). 1986 - 1987

Education

MPH | Harvard School of Public Health. 1997

MD | University of the Philippines College of Medicine (Philippines). 1986

Awards

American Thoracic Society Fellow. 2018

Elected to membership of the American Pediatric Society. 2015

Outstanding Achievement in Research – University of the Philippines Medical Alumni Society in America, Annual Grand Convention,. 2011

Outstanding Researcher – University of the Philippines Medical Alumni Society, Annual Homecoming,. 2011

Fellow of the American College of Chest Physicians. 1999

Research

Dr. Litonjua's research primarily deals with investigating factors that both increase and decrease the risk of developing asthma, wheezing, and allergic disorders in childhood. As part of this, he has investigated a broad range of prenatal and early life exposures including maternal diet, exposure t...
Dr. Litonjua's research primarily deals with investigating factors that both increase and decrease the risk of developing asthma, wheezing, and allergic disorders in childhood. As part of this, he has investigated a broad range of prenatal and early life exposures including maternal diet, exposure to allergens, exposure to early life environment (e.g. pets, daycare attendance, air pollution, etc). He co-led a clinical trial of vitamin D supplementation in pregnancy to prevent asthma in the offspring.

He has an interest in identifying genetic and epigenetic marks that affect asthma development and is also working on the interaction between these genetic and epigenetic factors and environmental exposures on the development of asthma and allergies.

Dr. Litonjua has begun to examine the role of the gut microbiome and the environmental microbiome in early life on the development of asthma and allergies in children.

Publications

Journal Articles

Comparison of Race-neutral Versus Race-specific Spirometry Equations for Evaluation of Child Asthma.

Non AL, Li X, Jones MR, Oken E, Hartert T, Schoettler N, Gold DR, Ramratnam S, Schauberger EM, Tantisira K, Bacharier LB, Conrad DJ, Carroll KN, Nkoy FL, Luttmann-Gibson H, Gilliland FD, Breton CV, Kattan M, Lemanske RF, Litonjua AA, McEvoy CT, Rivera-Spoljaric K, Rosas-Salazar C, Joseph CLM, Palmore M, Ryan PH, Wegienka G, Sitarik AR, Singh AM, Miller RL, Zoratti EM, Ownby D, Camargo CA, Aschner JL, Stroustrup A, Farzan SF, Karagas MR, Jackson DJ, Gern JE,

American journal of respiratory and critical care medicine.. 2024 December 6 Epub 12/06/2024.

Prenatal Diet and Infant Growth From Birth to Age 24 Months.

Hedderson MM, Schuh HB, Knapp EA, Bekelman TA, Catellier DJ, Westlake M, Lyall K, Schmidt RJ, Dunlop AL, Comstock SS, Chatzi L, Sauder KA, Dabelea D, Switkowski KM, Lin PD, Avalos LA, Zhu Y, Ferrara A,

JAMA network open.. 2024 November 47 (11):e2445771. Epub 11/04/2024.

Immunomodulatory metabolites in IgE-mediated food allergy and oral immunotherapy outcomes based on metabolomic profiling.

Virkud YV, Styles JN, Kelly RS, Patil SU, Ruiter B, Smith NP, Clish C, Wheelock CE, Celedón JC, Litonjua AA, Bunyavanich S, Weiss ST, Baker ES, Lasky-Su JA, Shreffler WG

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.. 2024 November 35 (11):e14267. Epub 1900 01 01.

Pregnancy complications and birth outcomes following low-level exposure to per- and polyfluoroalkyl substances in the vitamin D antenatal asthma reduction trial.

Begum S, Prince N, Mínguez-Alarcón L, Chen Y, Soeteman DI, Fangal V, Huang M, Wheelock C, Mendez K, Litonjua AA, Weiss ST, Lasky-Su J, Kelly RS

Environmental science. Advances.. 2024 October 23 (10):1426-1437. Epub 08/12/2024.

Do small effects matter more in vulnerable populations? an investigation using Environmental influences on Child Health Outcomes (ECHO) cohorts.

Peacock JL, Coto SD, Rees JR, Sauzet O, Jensen ET, Fichorova R, Dunlop AL, Paneth N, Padula A, Woodruff T, Morello-Frosch R, Trowbridge J, Goin D, Maldonado LE, Niu Z, Ghassabian A, Transande L, Ferrara A, Croen LA, Alexeeff S, Breton C, Litonjua A, O'Connor TG, Lyall K, Volk H, Alshawabkeh A, Manjourides J, Camargo CA, Dabelea D, Hockett CW, Bendixsen CG, Hertz-Picciotto I, Schmidt RJ, Hipwell AE, Keenan K, Karr C, LeWinn KZ, Lester B, Camerota M, Ganiban J, McEvoy C, Elliott MR, Sathyanarayana S, Ji N, Braun JM, Karagas MR,

BMC public health.. 2024 September 2824 (1):2655. Epub 09/28/2024.

Neighborhood Food Access in Early Life and Trajectories of Child Body Mass Index and Obesity.

Aris IM, Wu AJ, Lin PD, Zhang M, Farid H, Hedderson MM, Zhu Y, Ferrara A, Chehab RF, Barrett ES, Carnell S, Camargo CA, Chu SH, Mirzakhani H, Kelly RS, Comstock SS, Strakovsky RS, O'Connor TG, Ganiban JM, Dunlop AL, Dabelea D, Breton CV, Bastain TM, Farzan SF, Call CC, Hartert T, Snyder B, Santarossa S, Cassidy-Bushrow AE, O'Shea TM, McCormack LA, Karagas MR, McEvoy CT, Alshawabkeh A, Zimmerman E, Wright RJ, McCann M, Wright RO, Coull B, Amutah-Onukagha N, Hacker MR, James-Todd T, Oken E,

JAMA pediatrics.. 2024 September 16 Epub 09/16/2024.

Urinary eicosanoid levels in early life and risk of atopic disease in childhood.

Chen L, Brustad N, Kim M, Luo Y, Wang T, Ali M, Prince N, Chen Y, Chu S, Begum S, Mendez K, Kelly RS, Schoos AM, Rasmussen MA, Zurita J, Kolmert J, Stokholm J, Litonjua A, Weiss ST, Bønnelykke K, Wheelock CE, Lasky-Su J, Chawes B

The Journal of allergy and clinical immunology.. 2024 September 154 (3):670-678. Epub 06/01/2024.

Association of maternal fish consumption and ?-3 supplement use during pregnancy with child autism-related outcomes: results from a cohort consortium analysis.

Lyall K, Westlake M, Musci R, Gachigi K, Barrett ES, Bastain TM, Bush NR, Buss C, Camargo CA, Croen LA, Dabelea D, Dunlop AL, Elliott AJ, Ferrara A, Ghassabian A, Gern JE, Hare ME, Hertz-Picciotto I, Hipwell AE, Hockett CW, Karagas MR, Lugo-Candelas C, O'Connor TG, Schmidt RJ, Stanford JB, Straughen JK, Shuster CL, Wright RO, Wright RJ, Zhao Q, Oken E, , , , ,

The American journal of clinical nutrition.. 2024 September 120 (3):583-592. Epub 07/01/2024.

Bilirubin metabolism in early life and respiratory health during preschool age: A combined analysis of two independent birth cohorts.

Kim M, Brustad N, Eliasen AU, Ali M, Wang T, Rasmussen MA, Ernst M, Hougaard D, Litonjua AA, Wheelock CE, Kelly RS, Chen Y, Prince N, Townsend PA, Stokholm J, Weiss ST, Bønnelykke K, Lasky-Su J, Chawes B

Med.. 2024 August 13 Epub 08/13/2024.

Sociodemographic Correlates of High Cardiovascular Health Across Childhood and Adolescence: A Prospective Study Among 2 Cohorts in the ECHO Consortium.

Perng W, Galai N, Zhao Q, Litonjua A, Geiger S, Sauder KA, O'Shea TM, Hivert MF, Oken E, Dabelea D, Aris IM,

Journal of the American Heart Association.. 2024 August 613 (15):e036279. Epub 07/31/2024.

The metabolic role of vitamin D in children's neurodevelopment: a network study.

De Marzio M, Lasky-Su J, Chu SH, Prince N, Litonjua AA, Weiss ST, Kelly RS, Glass KR

Scientific reports.. 2024 July 2314 (1):16929. Epub 07/23/2024.

Preschool impulse oscillometry predicts active asthma and impaired lung function at school age.

Knihtilä HM, Stubbs BJ, Carey VJ, Laranjo N, Zeiger RS, Bacharier LB, O'Connor GT, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2024 July 154 (1):94-100.e13. Epub 01/18/2024.

Network Analysis Reveals Protein Modules Associated with Childhood Respiratory Diseases.

Prince N, Begum S, Mendez KM, Ramirez LG, Chen Y, Chen Q, Chu SH, Kachroo P, Levy O, Diray-Arce J, Palma P, Litonjua AA, Weiss ST, Kelly RS, Lasky-Su JA

bioRxiv : the preprint server for biology.. 2024 June 17 Epub 06/17/2024.

Metabolomics of IgE-Mediated Food Allergy and Oral Immunotherapy Outcomes based on Metabolomic Profiling.

Virkud YV, Styles JN, Kelly RS, Patil SU, Ruiter B, Smith NP, Clish C, Wheelock CE, Celedón JC, Litonjua AA, Bunyavanich S, Weiss ST, Baker ES, Lasky-Su JA, Shreffler WG

medRxiv : the preprint server for health sciences.. 2024 June 1 Epub 06/01/2024.

Host factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort Consortium.

McKee K, Bassis CM, Golob J, Palazzolo B, Sen A, Comstock SS, Rosas-Salazar C, Stanford JB, O'Connor T, Gern JE, Paneth N, Dunlop AL,

Scientific reports.. 2024 May 2314 (1):11798. Epub 05/23/2024.

The Association of Prenatal C-Reactive Protein and Interleukin-8 Levels with Maternal Characteristics and Preterm Birth.

Chen YS, Mirzakhani H, Knihtila H, Fichorova R, Luu N, Laranjo N, Kelly R, Weiss ST, Litonjua AA, Lee-Sarwar K

American journal of perinatology.. 2024 May 41 (S 01):e843-e852. Epub 10/14/2022.

Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study.

Aris IM, Lin PD, Wu AJ, Dabelea D, Lester BM, Wright RJ, Karagas MR, Kerver JM, Dunlop AL, Joseph CLM, Camargo CA, Ganiban JM, Schmidt RJ, Strakovsky RS, McEvoy CT, Hipwell AE, O'Shea TM, McCormack LA, Maldonado LE, Niu Z, Ferrara A, Zhu Y, Chehab RF, Kinsey EW, Bush NR, Nguyen RHN, Carroll KN, Barrett ES, Lyall K, Sims-Taylor LM, Trasande L, Biagini JM, Breton CV, Patti MA, Coull B, Amutah-Onukagha N, Hacker MR, James-Todd T, Oken E, , , Pb S, Lk N, Lp J, Dj C, G F, R G, D C,

The American journal of clinical nutrition.. 2024 May 119 (5):1216-1226. Epub 03/01/2024.

Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1.

Kilic A, Halu A, De Marzio M, Maiorino E, Duvall MG, Brueggemann T, Rojas Quintero JJ, Chase R, Mirzakhani H, Sungur AÖ, Koepke J, Nakano T, Peh HY, Krishnamoorthy N, Abdulnour RE, Georgopoulos K, Litonjua AA, Demay M, Renz H, Levy BD, Weiss ST

eLife.. 2024 April 312 Epub 04/03/2024.

Prenatal vitamin D supplementation to prevent childhood asthma: 15-year results from the Vitamin D Antenatal Asthma Reduction Trial (VDAART).

Weiss ST, Mirzakhani H, Carey VJ, O'Connor GT, Zeiger RS, Bacharier LB, Stokes J, Litonjua AA

The Journal of allergy and clinical immunology.. 2024 February 153 (2):378-388. Epub 10/16/2023.

Sphingolipid classes and the interrelationship with pediatric asthma and asthma risk factors.

Chen Y, Checa A, Zhang P, Huang M, Kelly RS, Kim M, Chen YS, Lee-Sarwar KA, Prince N, Mendez KM, Begum S, Kachroo P, Chu SH, Stokholm J, Bønnelykke K, Litonjua AA, Bisgaard H, Weiss ST, Chawes BL, Wheelock CE, Lasky-Su JA

Allergy.. 2024 February 79 (2):404-418. Epub 11/28/2023.

Association of Prenatal Maternal and Infant Vitamin D Supplementation with Offspring Asthma.

Ramirez LG, Lee-Sarwar K, Kelly RS, Weiss ST, Litonjua AA

Annals of the American Thoracic Society.. 2024 February 21 (2):279-286. Epub 1900 01 01.

Metabolomic data presents challenges for epidemiological meta-analysis: a case study of childhood body mass index from the ECHO consortium.

Prince N, Liang D, Tan Y, Alshawabkeh A, Angel EE, Busgang SA, Chu SH, Cordero JF, Curtin P, Dunlop AL, Gilbert-Diamond D, Giulivi C, Hoen AG, Karagas MR, Kirchner D, Litonjua AA, Manjourides J, McRitchie S, Meeker JD, Pathmasiri W, Perng W, Schmidt RJ, Watkins DJ, Weiss ST, Zens MS, Zhu Y, Lasky-Su JA, Kelly RS

Metabolomics : Official journal of the Metabolomic Society.. 2024 January 2420 (1):16. Epub 01/24/2024.

Bik promotes proteasomal degradation to control low-grade inflammation.

Mebratu YA, Jones JT, Liu C, Negasi ZH, Rahman M, Rojas-Quintero J, O'Connor GT, Gao W, Dupuis J, Cho MH, Litonjua AA, Randell S, Tesfaigzi Y

The Journal of clinical investigation.. 2023 December 19134 (4)Epub 12/19/2023.

Early life gut microbiome in children following spontaneous preterm birth and maternal preeclampsia.

Shadid ILC, Lee-Sarwar K, Lu Z, Yadama A, Laranjo N, Carey V, O'Connor GT, Zeiger RS, Bacharier L, Guchelaar HJ, Liu YY, Litonjua AA, Weiss ST, Mirzakhani H

iScience.. 2023 December 1526 (12):108311. Epub 10/28/2023.

Maternal vitamin D-related metabolome and offspring risk of asthma outcomes.

Kim M, Brustad N, Ali M, Gürdeniz G, Arendt M, Litonjua AA, Wheelock CE, Kelly RS, Chen Y, Prince N, Guo F, Zhou X, Stokholm J, Bønnelykke K, Weiss ST, Bisgaard H, Lasky-Su J, Chawes B

The Journal of allergy and clinical immunology.. 2023 December 152 (6):1646-1657.e11. Epub 08/08/2023.

Prenatal and perinatal influences on the microbiome: Clinical implications.

Lee-Sarwar KA, Liu YY, Litonjua AA, Weiss ST

The Journal of allergy and clinical immunology.. 2023 December 152 (6):1414-1416. Epub 09/29/2023.

Cord blood DNA methylation signatures associated with preeclampsia are enriched for cardiovascular pathways: insights from the VDAART trial.

Knihtilä HM, Kachroo P, Shadid I, Raissadati A, Peng C, McElrath TF, Litonjua AA, Demeo DL, Loscalzo J, Weiss ST, Mirzakhani H

EBioMedicine.. 2023 December 98 :104890. Epub 11/22/2023.

Genotype-microbiome-metabolome associations in early childhood, and their link to BMI and childhood obesity.

Aparicio A, Sun Z, Gold DR, Litonjua AA, Weiss ST, Lee-Sarwar K, Liu YY

medRxiv : the preprint server for health sciences.. 2023 November 13 Epub 11/13/2023.

Integration of circulating microRNAs and transcriptome signatures identifies early-pregnancy biomarkers of preeclampsia.

Mirzakhani H, Handy DE, Lu Z, Oppenheimer B, Litonjua AA, Loscalzo J, Weiss ST

Clinical and translational medicine.. 2023 November 13 (11):e1446. Epub 1900 01 01.

The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort.

Knapp EA, Kress AM, Parker CB, Page GP, McArthur K, Gachigi KK, Alshawabkeh AN, Aschner JL, Bastain TM, Breton CV, Bendixsen CG, Brennan PA, Bush NR, Buss C, Camargo CA, Catellier D, Cordero JF, Croen L, Dabelea D, Deoni S, D'Sa V, Duarte CS, Dunlop AL, Elliott AJ, Farzan SF, Ferrara A, Ganiban JM, Gern JE, Giardino AP, Towe-Goodman NR, Gold DR, Habre R, Hamra GB, Hartert T, Herbstman JB, Hertz-Picciotto I, Hipwell AE, Karagas MR, Karr CJ, Keenan K, Kerver JM, Koinis-Mitchell D, Lau B, Lester BM, Leve LD, Leventhal B, LeWinn KZ, Lewis J, Litonjua AA, Lyall K, Madan JC, McEvoy CT, McGrath M, Meeker JD, Miller RL, Morello-Frosch R, Neiderhiser JM, O'Connor TG, Oken E, O'Shea M, Paneth N, Porucznik CA, Sathyanarayana S, Schantz SL, Spindel ER, Stanford JB, Stroustrup A, Teitelbaum SL, Trasande L, Volk H, Wadhwa PD, Weiss ST, Woodruff TJ, Wright RJ, Zhao Q, Jacobson LP, Environmental Influences On Child Health Outcomes OBOPCF

American journal of epidemiology.. 2023 August 4192 (8):1249-1263. Epub 1900 01 01.

Sociodemographic Differences in COVID-19 Pandemic Experiences Among Families in the United States.

LeWinn KZ, Trasande L, Law A, Blackwell CK, Bekelman TA, Arizaga JA, Sullivan AA, Bastain TM, Breton CV, Karagas MR, Elliott AJ, Karr CJ, Carroll KN, Dunlop AL, Croen LA, Margolis AE, Alshawabkeh AN, Cordero JF, Singh AM, Seroogy CM, Jackson DJ, Wood RA, Hartert TV, Kim YS, Duarte CS, Schweitzer JB, Lester BM, McEvoy CT, O'Connor TG, Oken E, Bornkamp N, Brown ED, Porucznik CA, Ferrara A, Camargo CA, Zhao Q, Ganiban JM, Jacobson LP,

JAMA network open.. 2023 August 16 (8):e2330495. Epub 08/01/2023.

The relationship of fetal sex and maternal race and ethnicity with early and late pregnancy C-reactive protein and interleukin-8.

Jha A, Baumann N, Shadid I, Shah J, Chen YS, Lee-Sarwar KA, Zeiger RS, O'Connor GT, Bacharier LB, Carey VJ, Laranjo N, Fichorova RN, Litonjua AA, Weiss ST, Mirzakhani H

American journal of reproductive immunology : AJRI.. 2023 August 90 (2):e13746. Epub 1900 01 01.

Do You Inquire About Hormonal Treatment in Female Patients Consulting for New Onset Asthma or Asthma Exacerbation?

Leynaert B, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2023 August 11 (8):2491-2492. Epub 1900 01 01.

The metabolic role of vitamin D in children's neurodevelopment: a network study.

De Marzio M, Lasky-Su J, Chu SH, Prince N, Litonjua AA, Weiss ST, Kelly RS, Glass KR

bioRxiv : the preprint server for biology.. 2023 July 15 Epub 07/15/2023.

Metabolomics and Self-Reported Depression, Anxiety, and Phobic Symptoms in the VA Normative Aging Study.

Prince N, Stav M, Cote M, Chu SH, Vyas CM, Okereke OI, Palacios N, Litonjua AA, Vokonas P, Sparrow D, Spiro A, Lasky-Su JA, Kelly RS

Metabolites.. 2023 July 1513 (7)Epub 07/15/2023.

Incidence rates of childhood asthma with recurrent exacerbations in the US Environmental influences on Child Health Outcomes (ECHO) program.

Miller RL, Schuh H, Chandran A, Aris IM, Bendixsen C, Blossom J, Breton C, Camargo CA, Canino G, Carroll KN, Commodore S, Cordero JF, Dabelea DM, Ferrara A, Fry RC, Ganiban JM, Gern JE, Gilliland FD, Gold DR, Habre R, Hare ME, Harte RN, Hartert T, Hasegawa K, Khurana Hershey GK, Jackson DJ, Joseph C, Kerver JM, Kim H, Litonjua AA, Marsit CJ, McEvoy C, Mendonça EA, Moore PE, Nkoy FL, O'Connor TG, Oken E, Ownby D, Perzanowski M, Rivera-Spoljaric K, Ryan PH, Singh AM, Stanford JB, Wright RJ, Wright RO, Zanobetti A, Zoratti E, Johnson CC,

The Journal of allergy and clinical immunology.. 2023 July 152 (1):84-93. Epub 03/25/2023.

Early-Life Weight Status and Risk of Childhood Asthma or Recurrent Wheeze in Preterm and Term Offspring.

Shah J, Shadid ILC, Carey VJ, Laranjo N, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST, Mirzakhani H

The journal of allergy and clinical immunology. In practice.. 2023 July 11 (7):2125-2132.e1. Epub 04/23/2023.

Elevated third trimester corticosteroid levels are associated with fewer offspring infections.

Prince N, Kelly RS, Chu SH, Kachroo P, Chen Y, Mendez KM, Begum S, Bisgaard H, Bønnelykke K, Kim M, Levy O, Litonjua AA, Wheelock CE, Weiss ST, Chawes BL, Lasky-Su JA

Scientific reports.. 2023 June 2813 (1):10461. Epub 06/28/2023.

Sociodemographic Variation in Children's Health Behaviors During the COVID-19 Pandemic.

Bekelman TA, Knapp EA, Dong Y, Dabelea D, Bastain TM, Breton CV, Carroll KN, Camargo CA, Davis AM, Dunlop AL, Elliott AJ, Ferrara A, Fry RC, Ganiban JM, Gilbert-Diamond D, Gilliland FD, Hedderson MM, Hipwell AE, Hockett CW, Huddleston KC, Karagas MR, Kelly N, Lai JS, Lester BM, Lucchini M, Melough MM, Mihalopoulos NL, O'Shea TM, Rundle AG, Stanford JB, VanBronkhorst S, Wright RJ, Zhao Q, Sauder KA,

Childhood obesity.. 2023 June 19 (4):226-238. Epub 07/19/2022.

Environmental and genetic associations with aberrant early-life gut microbial maturation in childhood asthma.

Chen YC, Chen Y, Lasky-Su J, Kelly RS, Stokholm J, Bisgaard H, Bønnelykke K, Pedersen CT, Chawes B, Laranjo N, Weiss ST, Litonjua AA, Lee-Sarwar K

The Journal of allergy and clinical immunology.. 2023 June 151 (6):1494-1502.e14. Epub 01/14/2023.

Corrigendum to "Plasma concentrations of per- and polyfluoroalkyl substances are associated with perturbations in lipid and amino acid metabolism" [Chemosphere 324 (2023)138228].

Prince N, Begum S, Mínguez-Alarcón L, Génard-Walton M, Huang M, Soeteman DI, Wheelock C, Litonjua AA, Weiss ST, Kelly RS, Lasky-Su J

Chemosphere.. 2023 June 327 :138420. Epub 03/28/2023.

The Impact of Baseline 25-Hydroxyvitamin D Level and Gestational Age on Prenatal Vitamin D Supplementation to Prevent Offspring Asthma or Recurrent Wheezing.

Shadid ILC, Brustad N, Lu M, Chawes BL, Bisgaard H, Zeiger RS, O'Connor GT, Bacharier LB, Guchelaar HJ, Litonjua AA, Weiss ST, Mirzakhani H

The American journal of clinical nutrition.. 2023 June 117 (6):1342-1352. Epub 04/17/2023.

Omega-3 Fatty Acids Interact with Region Genotype in Association with Childhood Atopy.

Lee-Sarwar KA, Fischer-Rasmussen K, Bønnelykke K, Bisgaard H, Chawes B, Kelly RS, Lasky-Su J, Zeiger RS, O'Connor GT, Bacharier LB, Carey VJ, Laranjo N, Litonjua AA, Weiss ST

Nutrients.. 2023 May 2215 (10)Epub 05/22/2023.

Plasma concentrations of per- and polyfluoroalkyl substances are associated with perturbations in lipid and amino acid metabolism.

Prince N, Begum S, Mínguez-Alarcón L, Génard-Walton M, Huang M, Soeteman DI, Wheelock C, Litonjua AA, Weiss ST, Kelly RS, Lasky-Su J

Chemosphere.. 2023 May 324 :138228. Epub 03/04/2023.

Association of Vitamin D Level and Maternal Gut Microbiome during Pregnancy: Findings from a Randomized Controlled Trial of Antenatal Vitamin D Supplementation.

Aparicio A, Gold DR, Weiss ST, Litonjua AA, Lee-Sarwar K, Liu YY

Nutrients.. 2023 April 2515 (9)Epub 04/25/2023.

Association of vitamin D level and maternal gut microbiome during pregnancy: Findings from a randomized controlled trial of antenatal vitamin D supplementation.

Aparicio A, Gold DR, Weiss ST, Litonjua AA, Lee-Sarwar K, Liu YY

medRxiv : the preprint server for health sciences.. 2023 April 5 Epub 04/05/2023.

Changes in Body Mass Index Among School-Aged Youths Following Implementation of the Healthy, Hunger-Free Kids Act of 2010.

Chandran A, Burjak M, Petimar J, Hamra G, Melough MM, Dunlop AL, Snyder BM, Litonjua AA, Hartert T, Gern J, Alshawabkeh AN, Aschner J, Camargo CA, Dabelea D, Duarte CS, Ferrara A, Ganiban JM, Gilliland F, Gold DR, Hedderson M, Herbstman JB, Hockett C, Karagas MR, Kerver JM, Lee-Sarwar KA, Lester B, McEvoy CT, Niu Z, Stanford JB, Wright R, Zimmerman E, Farzan S, Zhang Z, Knapp E

JAMA pediatrics.. 2023 April 1177 (4):401-409. Epub 1900 01 01.

Revealing the importance of prenatal gut microbiome in offspring neurodevelopment in humans.

Sun Z, Lee-Sarwar K, Kelly RS, Lasky-Su JA, Litonjua AA, Weiss ST, Liu YY

EBioMedicine.. 2023 April 90 :104491. Epub 03/01/2023.

Predicting metabolomic profiles from microbial composition through neural ordinary differential equations.

Wang T, Wang XW, Lee-Sarwar KA, Litonjua AA, Weiss ST, Sun Y, Maslov S, Liu YY

Nature machine intelligence.. 2023 March 5 (3):284-293. Epub 03/13/2023.

Benchmarking omics-based prediction of asthma development in children.

Wang XW, Wang T, Schaub DP, Chen C, Sun Z, Ke S, Hecker J, Maaser-Hecker A, Zeleznik OA, Zeleznik R, Litonjua AA, DeMeo DL, Lasky-Su J, Silverman EK, Liu YY, Weiss ST

Respiratory research.. 2023 February 2624 (1):63. Epub 02/26/2023.

The maternal prenatal and offspring early-life gut microbiome of childhood asthma phenotypes.

Lee-Sarwar KA, Chen YC, Chen YY, Kozyrskyj AL, Mandhane PJ, Turvey SE, Subbarao P, Bisgaard H, Stokholm J, Chawes B, Sørensen SJ, Kelly RS, Lasky-Su J, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Carey VJ, Harshfield BJ, Laranjo N, Gold DR, Weiss ST, Litonjua AA

Allergy.. 2023 February 78 (2):418-428. Epub 09/24/2022.

Maternal vitamin D status modifies the effects of early life tobacco exposure on child lung function.

Knihtilä HM, Huang M, Prince N, Stubbs BJ, Carey VJ, Laranjo N, Mirzakhani H, Zeiger RS, Bacharier LB, O'Connor GT, Litonjua AA, Weiss ST, Lasky-Su J

The Journal of allergy and clinical immunology.. 2023 February 151 (2):556-564. Epub 11/16/2022.

Early-life fecal metabolomics of food allergy.

Lee-Sarwar KA, Chen YC, Lasky-Su J, Kelly RS, Zeiger RS, O'Connor GT, Bacharier LB, Jia X, Beigelman A, Gold DR, Laranjo N, Bunyavanich S, Weiss ST, Litonjua AA, Brennan PJ

Allergy.. 2023 February 78 (2):512-521. Epub 12/07/2022.

Extracellular Vesicle-Encapsulated microRNAs as Novel Biomarkers of Lung Health.

Eckhardt CM, Gambazza S, Bloomquist TR, De Hoff P, Vuppala A, Vokonas PS, Litonjua AA, Sparrow D, Parvez F, Laurent LC, Schwartz J, Baccarelli AA, Wu H

American journal of respiratory and critical care medicine.. 2023 January 1207 (1):50-59. Epub 1900 01 01.

Association of Severe Bronchiolitis during Infancy with Childhood Asthma Development: An Analysis of the ECHO Consortium.

Nanishi M, Chandran A, Li X, Stanford JB, Alshawabkeh AN, Aschner JL, Dabelea D, Dunlop AL, Elliott AJ, Gern JE, Hartert T, Herbstman J, Hershey GKK, Hipwell AE, Karagas MR, Karr CJ, Leve LD, Litonjua AA, McEvoy CT, Miller RL, Oken E, O'Shea TM, Paneth N, Weiss ST, Wright RO, Wright RJ, Carroll KN, Zhang X, Zhao Q, Zoratti E, Camargo CA, Hasegawa K,

Biomedicines.. 2022 December 2211 (1)Epub 12/22/2022.

Maternal Inflammatory Biomarkers during Pregnancy and Early Life Neurodevelopment in Offspring: Results from the VDAART Study.

Kelly RS, Lee-Sarwar K, Chen YC, Laranjo N, Fichorova R, Chu SH, Prince N, Lasky-Su J, Weiss ST, Litonjua AA

International journal of molecular sciences.. 2022 December 323 (23)Epub 12/03/2022.

The Association of Prenatal C-Reactive Protein Levels With Childhood Asthma and Atopy.

Chen YS, Lee-Sarwar KA, Mirzakhani H, O'Connor GT, Bacharier LB, Zeiger RS, Knihtilä HM, Jha A, Kelly RS, Laranjo N, Fichorova RN, Luu N, Weiss ST, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2022 December 10 (12):3213-3219.e11. Epub 09/13/2022.

Reduced Steroid Metabolites Identify Infection-Prone Children in Two Independent Pre-Birth Cohorts.

Prince N, Kim M, Kelly RS, Diray-Arce J, Bønnelykke K, Chawes BL, Huang M, Levy O, Litonjua AA, Stokholm J, Wheelock CE, Bisgaard H, Weiss ST, Lasky-Su JA

Metabolites.. 2022 November 1312 (11)Epub 11/13/2022.

Metabolomic differences in lung function metrics: evidence from two cohorts.

Kelly RS, Stewart ID, Bayne H, Kachroo P, Spiro Iii A, Vokonas P, Sparrow D, Weiss ST, Knihtilä HM, Litonjua AA, Wareham NJ, Langenberg C, Lasky-Su JA

Thorax.. 2022 September 77 (9):919-928. Epub 10/14/2021.

Association of the gut microbiome and metabolome with wheeze frequency in childhood asthma.

Lee-Sarwar K, Dedrick S, Momeni B, Kelly RS, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Lasky-Su J, Litonjua AA, Liu YY, Weiss ST

The Journal of allergy and clinical immunology.. 2022 August 150 (2):325-336. Epub 02/20/2022.

Circulating levels of maternal vitamin D and risk of ADHD in offspring: results from the Vitamin D Antenatal Asthma Reduction Trial.

Chu SH, Huang M, Kelly RS, Kachroo P, Litonjua AA, Weiss ST, Lasky-Su J

International journal of epidemiology.. 2022 June 1351 (3):910-918. Epub 1900 01 01.

The Role of Childhood Asthma in Obesity Development: A Nationwide US Multicohort Study.

Stratakis N, Garcia E, Chandran A, Hsu T, Alshawabkeh A, Aris IM, Aschner JL, Breton C, Burbank A, Camargo CA, Carroll KN, Chen Z, Claud EC, Dabelea D, Dunlop AL, Elliott AJ, Ferrara A, Ganiban JM, Gern JE, Gold DR, Gower WA, Hertz-Picciotto I, Karagas MR, Karr CJ, Lester B, Leve LD, Litonjua AA, Ludena Y, McEvoy CT, Miller RL, Mueller NT, O'Connor TG, Oken E, O'Shea TM, Perera F, Stanford JB, Rivera-Spoljaric K, Rundle A, Trasande L, Wright RJ, Zhang Y, Zhu Y, Berhane K, Gilliland F, Chatzi L,

Epidemiology.. 2022 January 133 (1):131-140. Epub 1900 01 01.

Correction: Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: Findings from the ECHO cohorts.

Dunlop AL, Essalmi AG, Avalos L, Breton C, Camargo CA, Cowell WJ, Dabelea D, Dager SR, Duarte C, Elliott A, Fichorova R, Gern J, Hedderson MM, Thepaksorn EH, Huddleston K, Karagas MR, Kleinman K, Leve L, Li X, Li Y, Litonjua A, Ludena-Rodriguez Y, Madan JC, Nino JM, McEvoy C, O'Connor TG, Padula AM, Paneth N, Perera F, Sathyanarayana S, Schmidt RJ, Schultz RT, Snowden J, Stanford JB, Trasande L, Volk HE, Wheaton W, Wright RJ, McGrath M,

PloS one.. 2022 17 (5):e0268423. Epub 05/06/2022.

Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation.

Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, Reese SE, Page CM, Gruzieva O, Rzehak P, Gao L, Bakulski KM, Novoloaca A, Allard C, Pappa I, Llambrich M, Vives M, Jima DD, Kvist T, Baccarelli A, White C, Rezwan FI, Sharp GC, Tindula G, Bergström A, Grote V, Dou JF, Isaevska E, Magnus MC, Corpeleijn E, Perron P, Jaddoe VWV, Nohr EA, Maitre L, Foraster M, Hoyo C, Håberg SE, Lahti J, DeMeo DL, Zhang H, Karmaus W, Kull I, Koletzko B, Feinberg JI, Gagliardi L, Bouchard L, Ramlau-Hansen CH, Tiemeier H, Santorelli G, Maguire RL, Czamara D, Litonjua AA, Langhendries JP, Plusquin M, Lepeule J, Binder EB, Verduci E, Dwyer T, Carracedo Á, Ferre N, Eskenazi B, Kogevinas M, Nawrot TS, Munthe-Kaas MC, Herceg Z, Relton C, Melén E, Gruszfeld D, Breton C, Fallin MD, Ghantous A, Nystad W, Heude B, Snieder H, Hivert MF, Felix JF, Sørensen TIA, Bustamante M, Murphy SK, Raikkönen K, Oken E, Holloway JW, Arshad SH, London SJ, Holland N

Mutation research. Reviews in mutation research.. 2022 789 :108415. Epub 03/14/2022.

The Association of Prenatal Vitamin D Sufficiency With Aeroallergen Sensitization and Allergic Rhinitis in Early Childhood.

Chen YS, Mirzakhani H, Lu M, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Carey VJ, Harshfield BJ, Laranjo N, Litonjua AA, Weiss ST, Lee-Sarwar KA

The journal of allergy and clinical immunology. In practice.. 2021 October 9 (10):3788-3796.e3. Epub 06/21/2021.

The effect of air pollution on the transcriptomics of the immune response to respiratory infection.

Croft DP, Burton DS, Nagel DJ, Bhattacharya S, Falsey AR, Georas SN, Hopke PK, Johnston CJ, Kottmann RM, Litonjua AA, Mariani TJ, Rich DQ, Thevenet-Morrison K, Thurston SW, Utell MJ, McCall MN

Scientific reports.. 2021 September 3011 (1):19436. Epub 09/30/2021.

US Childhood Asthma Incidence Rate Patterns From the ECHO Consortium to Identify High-risk Groups for Primary Prevention.

Johnson CC, Chandran A, Havstad S, Li X, McEvoy CT, Ownby DR, Litonjua AA, Karagas MR, Camargo CA, Gern JE, Gilliland F, Togias A,

JAMA pediatrics.. 2021 September 1175 (9):919-927. Epub 1900 01 01.

Maternal 17q21 genotype influences prenatal vitamin D effects on offspring asthma/recurrent wheeze.

Knihtilä HM, Kelly RS, Brustad N, Huang M, Kachroo P, Chawes BL, Stokholm J, Bønnelykke K, Pedersen CT, Bisgaard H, Litonjua AA, Lasky-Su JA, Weiss ST

The European respiratory journal.. 2021 September 58 (3)Epub 09/23/2021.

Diet and asthma: Is the sum more important than the parts?

Reyes-Angel J, Han YY, Litonjua AA, Celedón JC

The Journal of allergy and clinical immunology.. 2021 September 148 (3):706-707. Epub 05/06/2021.

Beyond obesity: The complex relationship between early growth trajectories and later lung function.

Krol KA, Litonjua AA

The Journal of allergy and clinical immunology.. 2021 September 148 (3):713-715. Epub 07/24/2021.

Low gestational vitamin D level and childhood asthma are related to impaired lung function in high-risk children.

Knihtilä HM, Stubbs BJ, Carey VJ, Laranjo N, Chu SH, Kelly RS, Zeiger RS, Bacharier LB, O'Connor GT, Lasky-Su J, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2021 July 148 (1):110-119.e9. Epub 01/22/2021.

High-dose vitamin D during pregnancy and pathway gene polymorphisms in prevention of offspring persistent wheeze.

Brustad N, Greve JH, Mirzakhani H, Pedersen CT, Eliasen AU, Stokholm J, Lasky-Su J, Bønnelykke K, Litonjua AA, Weiss ST, Bisgaard H, Chawes BL

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.. 2021 May 32 (4):679-689. Epub 02/20/2021.

Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification.

Li J, Tiwari A, Mirzakhani H, Wang AL, Kho AT, McGeachie MJ, Litonjua AA, Weiss ST, Tantisira KG

Journal of personalized medicine.. 2021 April 1611 (4)Epub 04/16/2021.

Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype.

Rago D, Pedersen CT, Huang M, Kelly RS, Gürdeniz G, Brustad N, Knihtil H, Lee-Sarwar KA, Morin A, Rasmussen MA, Stokholm J, Bønnelykke K, Litonjua AA, Wheelock CE, Weiss ST, Lasky-Su J, Bisgaard H, Chawes BL

American journal of respiratory and critical care medicine.. 2021 April 1203 (7):853-863. Epub 1900 01 01.

Effect of early and late prenatal vitamin D and maternal asthma status on offspring asthma or recurrent wheeze.

Lu M, Litonjua AA, O'Connor GT, Zeiger RS, Bacharier L, Schatz M, Carey VJ, Weiss ST, Mirzakhani H

The Journal of allergy and clinical immunology.. 2021 April 147 (4):1234-1241.e3. Epub 08/19/2020.

Contributions of asthma, rhinitis and IgE to exhaled nitric oxide in adolescents.

Flashner BM, Rifas-Shiman SL, Oken E, Camargo CA, Platts-Mills TAE, Workman L, Litonjua AA, Gold DR, Rice MB

ERJ open research.. 2021 April 7 (2)Epub 04/19/2021.

Perinatal granulopoiesis and risk of pediatric asthma.

Turturice BA, Theorell J, Koenig MD, Tussing-Humphreys L, Gold DR, Litonjua AA, Oken E, Rifas-Shiman SL, Perkins DL, Finn PW

eLife.. 2021 February 1010 Epub 02/10/2021.

Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: Findings from the ECHO cohorts.

Dunlop AL, Essalmi AG, Alvalos L, Breton C, Camargo CA, Cowell WJ, Dabelea D, Dager SR, Duarte C, Elliott A, Fichorova R, Gern J, Hedderson MM, Thepaksorn EH, Huddleston K, Karagas MR, Kleinman K, Leve L, Li X, Li Y, Litonjua A, Ludena-Rodriguez Y, Madan JC, Nino JM, McEvoy C, O'Connor TG, Padula AM, Paneth N, Perera F, Sathyanarayana S, Schmidt RJ, Schultz RT, Snowden J, Stanford JB, Trasande L, Volk HE, Wheaton W, Wright RJ, McGrath M,

PloS one.. 2021 16 (1):e0245064. Epub 01/08/2021.

Associations of ?- and ?-tocopherol during early life with lung function in childhood.

Kumar R, Ferrie R, Balmert L, Kienzl M, Rifas-Shiman SL, Gold DR, Sordillo JE, Kleinman K, Camargo CA, Litonjua AA, Oken E, Cook-Mills J

The Journal of allergy and clinical immunology.. 2020 December 146 (6):1349-1357.e3. Epub 04/25/2020.

Metabolomic signatures of lead exposure in the VA Normative Aging Study.

Kelly RS, Bayne H, Spiro A, Vokonas P, Sparrow D, Weiss ST, Schwartz J, Nassan FL, Lee-Sarwar K, Huang M, Kachroo P, Chu SH, Litonjua AA, Lasky-Su JA

Environmental research.. 2020 November 190 :110022. Epub 08/11/2020.

Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta.

Yadama AP, Maiorino E, Carey VJ, McElrath TF, Litonjua AA, Loscalzo J, Weiss ST, Mirzakhani H

Scientific reports.. 2020 October 1210 (1):17029. Epub 10/12/2020.

Delayed Motor Milestones Achievement in Infancy Associates with Perturbations of Amino Acids and Lipid Metabolic Pathways.

Vinding RK, Rago D, Kelly RS, Gürdeniz G, Rasmussen MA, Stokholm J, Bønnelykke K, Litonjua AA, Weiss ST, Lasky-Su J, Bisgaard H, Chawes BL

Metabolites.. 2020 August 1910 (9)Epub 08/19/2020.

Stability of developmental status and risk of impairment at 24 and 36 months in late preterm infants.

Mirzakhani H, Kelly RS, Yadama AP, Chu SH, Lasky-Su JA, Litonjua AA, Weiss ST

Infant behavior & development.. 2020 August 60 :101462. Epub 06/26/2020.

Association of Neutrophil to Lymphocyte Ratio With Pulmonary Function in a 30-Year Longitudinal Study of US Veterans.

Gao X, Coull B, Lin X, Vokonas P, Sparrow D, Hou L, DeMeo DL, Litonjua AA, Schwartz J, Baccarelli AA

JAMA network open.. 2020 July 13 (7):e2010350. Epub 07/01/2020.

Vitamin D Sufficiency Has a Limited Effect on Placental Structure and Pathology: Placental Phenotypes in the VDAART Trial.

He M, Mirzakhani H, Chen L, Wu R, Litonjua AA, Bacharier L, Weiss ST, Nelson DM

Endocrinology.. 2020 June 1161 (6)Epub 1900 01 01.

Metabolome-Microbiome Crosstalk and Human Disease.

Lee-Sarwar KA, Lasky-Su J, Kelly RS, Litonjua AA, Weiss ST

Metabolites.. 2020 May 110 (5)Epub 05/01/2020.

Plasma 25-Hydroxyvitamin D Concentrations are Associated with Polyunsaturated Fatty Acid Metabolites in Young Children: Results from the Vitamin D Antenatal Asthma Reduction Trial.

Huang M, Kelly RS, Kachroo P, Chu SH, Lee-Sarwar K, Chawes BL, Bisgaard H, Litonjua AA, Weiss ST, Lasky-Su J

Metabolites.. 2020 April 1410 (4)Epub 04/14/2020.

Determinants and Measurement of Neonatal Vitamin D: Overestimation of 25(OH)D in Cord Blood Using CLIA Assay Technology.

Lu M, Hollis BW, Carey VJ, Laranjo N, Singh RJ, Weiss ST, Litonjua AA

The Journal of clinical endocrinology and metabolism.. 2020 April 1105 (4):e1085-92. Epub 1900 01 01.

Gut Microbial-Derived Metabolomics of Asthma.

Lee-Sarwar KA, Lasky-Su J, Kelly RS, Litonjua AA, Weiss ST

Metabolites.. 2020 March 610 (3)Epub 03/06/2020.

Fecal short-chain fatty acids in pregnancy and offspring asthma and allergic outcomes.

Lee-Sarwar KA, Kelly RS, Lasky-Su J, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Rifas-Shiman SL, Carey VJ, Harshfield BJ, Laranjo N, Gold DR, Weiss ST, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2020 March 8 (3):1100-1102.e13. Epub 09/05/2019.

Associations of Prenatal Dietary Inflammatory Potential with Childhood Respiratory Outcomes in Project Viva.

Hanson C, Rifas-Shiman SL, Shivappa N, Wirth MD, Hebert JR, Gold D, Camargo CA, Sen S, Sordillo JE, Oken E, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2020 March 8 (3):945-952.e4. Epub 10/31/2019.

Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction.

Litonjua AA, Carey VJ, Laranjo N, Stubbs BJ, Mirzakhani H, O'Connor GT, Sandel M, Beigelman A, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST

The New England journal of medicine.. 2020 February 6382 (6):525-533. Epub 1900 01 01.

Obesity, sedentary lifestyle, and exhaled nitric oxide in an early adolescent cohort.

Flashner BM, Rifas-Shiman SL, Oken E, Camargo CA, Platts-Mills TJ, Workman L, Litonjua AA, Gold DR, Rice MB

Pediatric pulmonology.. 2020 February 55 (2):503-509. Epub 12/05/2019.

Asthma epidemiology and risk factors.

Stern J, Pier J, Litonjua AA

Seminars in immunopathology.. 2020 February 42 (1):5-15. Epub 02/04/2020.

Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring.

Kachroo P, Kelly RS, Mirzakhani H, Lee-Sarwar K, Chawes BL, Blighe K, Davaasambuu G, Bisgaard H, Litonjua AA, Weiss ST, Lasky-Su J

The journal of allergy and clinical immunology. In practice.. 2020 January 8 (1):388-391.e2. Epub 06/19/2019.

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium.

Howe CG, Cox B, Fore R, Jungius J, Kvist T, Lent S, Miles HE, Salas LA, Rifas-Shiman S, Starling AP, Yousefi P, Ladd-Acosta C, Baccarelli A, Binder EB, Chatzi VL, Czamara D, Dabelea D, DeMeo DL, Ghantous A, Herceg Z, Kajantie E, Lahti JMT, Lawlor DA, Litonjua A, Nawrot TS, Nohr EA, Oken E, Pizzi C, Plusquin M, Räikkönen K, Relton CL, Sharp GC, Sørensen TIA, Sunyer J, Vrijheid M, Zhang W, Hivert MF, Breton CV

Diabetes care.. 2020 January 43 (1):98-105. Epub 10/10/2019.

Allergic disease and low ASQ communication score in children.

Yadama AP, Kelly RS, Lee-Sarwar K, Mirzakhani H, Chu SH, Kachroo P, Litonjua AA, Lasky-Su J, Weiss ST

Brain, behavior, and immunity.. 2020 January 83 :293-297. Epub 10/10/2019.

Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth.

Yadama AP, Mirzakhani H, McElrath TF, Litonjua AA, Weiss ST

PloS one.. 2020 15 (1):e0227193. Epub 01/29/2020.

Prenatal oxidative balance and risk of asthma and allergic disease in adolescence.

Sordillo JE, Rifas-Shiman SL, Switkowski K, Coull B, Gibson H, Rice M, Platts-Mills TAE, Kloog I, Litonjua AA, Gold DR, Oken E

The Journal of allergy and clinical immunology.. 2019 December 144 (6):1534-1541.e5. Epub 08/19/2019.

The role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D.

Kelly RS, Chawes BL, Guo F, Zhang L, Blighe K, Litonjua AA, Raby BA, Levy BD, Rago D, Stokholm J, Bønnelykke K, Bisgaard H, Zhou X, Lasky-Su JA, Weiss ST

The European respiratory journal.. 2019 October 54 (4)Epub 10/24/2019.

Maternal Asthma, Preeclampsia, and Risk for Childhood Asthma at Age Six.

Mirzakhani H, Carey VJ, McElrath TF, Hollis BW, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST

American journal of respiratory and critical care medicine.. 2019 September 1200 (5):638-642. Epub 1900 01 01.

Socioeconomic status and DNA methylation from birth through mid-childhood: a prospective study in Project Viva.

Laubach ZM, Perng W, Cardenas A, Rifas-Shiman SL, Oken E, DeMeo D, Litonjua AA, Duca RC, Godderis L, Baccarelli A, Hivert MF

Epigenomics.. 2019 September 11 (12):1413-1427. Epub 09/11/2019.

Integrative analysis of the intestinal metabolome of childhood asthma.

Lee-Sarwar KA, Kelly RS, Lasky-Su J, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2019 August 144 (2):442-454. Epub 03/23/2019.

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns.

Kazmi N, Sharp GC, Reese SE, Vehmeijer FO, Lahti J, Page CM, Zhang W, Rifas-Shiman SL, Rezwan FI, Simpkin AJ, Burrows K, Richardson TG, Santos Ferreira DL, Fraser A, Harmon QE, Zhao S, Jaddoe VWV, Czamara D, Binder EB, Magnus MC, Håberg SE, Nystad W, Nohr EA, Starling AP, Kechris KJ, Yang IV, DeMeo DL, Litonjua AA, Baccarelli A, Oken E, Holloway JW, Karmaus W, Arshad SH, Dabelea D, Sørensen TIA, Laivuori H, Raikkonen K, Felix JF, London SJ, Hivert MF, Gaunt TR, Lawlor DA, Relton CL

Hypertension.. 2019 August 74 (2):375-383. Epub 06/24/2019.

The nasal methylome as a biomarker of asthma and airway inflammation in children.

Cardenas A, Sordillo JE, Rifas-Shiman SL, Chung W, Liang L, Coull BA, Hivert MF, Lai PS, Forno E, Celedón JC, Litonjua AA, Brennan KJ, DeMeo DL, Baccarelli AA, Oken E, Gold DR

Nature communications.. 2019 July 1210 (1):3095. Epub 07/12/2019.

Maternal corticotropin-releasing hormone is associated with LEP DNA methylation at birth and in childhood: an epigenome-wide study in Project Viva.

Tian FY, Rifas-Shiman SL, Cardenas A, Baccarelli AA, DeMeo DL, Litonjua AA, Rich-Edwards JW, Gillman MW, Oken E, Hivert MF

International journal of obesity : journal of the International Association for the Study of Obesity.. 2019 June 43 (6):1244-1255. Epub 11/21/2018.

Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva.

Peng C, Cardenas A, Rifas-Shiman SL, Hivert MF, Gold DR, Platts-Mills TA, Lin X, Oken E, Avila L, Celedón JC, Weiss ST, Baccarelli AA, Litonjua AA, DeMeo DL

The Journal of allergy and clinical immunology.. 2019 June 143 (6):2263-2270.e14. Epub 02/06/2019.

Epigenome-wide association study reveals methylation pathways associated with childhood allergic sensitization.

Peng C, Van Meel ER, Cardenas A, Rifas-Shiman SL, Sonawane AR, Glass KR, Gold DR, Platts-Mills TA, Lin X, Oken E, Hivert MF, Baccarelli AA, De Jong NW, Felix JF, Jaddoe VW, Duijts L, Litonjua AA, DeMeo DL

Epigenetics.. 2019 May 14 (5):445-466. Epub 03/28/2019.

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAS, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin MR, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Gong YY, Richiardi L, Kogevinas M, Litonjua AA, Eskenazi B, Huen K, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli AA, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert MF, Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder EB, Davey Smith G, Jaddoe VWV, Lie RT, Nystad W, London SJ, Lawlor DA, Relton CL, Snieder H, Felix JF

Nature communications.. 2019 April 2310 (1):1893. Epub 04/23/2019.

Racial/Ethnic Differences in Incidence and Persistence of Childhood Atopic Dermatitis.

Kim Y, Blomberg M, Rifas-Shiman SL, Camargo CA, Gold DR, Thyssen JP, Litonjua AA, Oken E, Asgari MM

The Journal of investigative dermatology.. 2019 April 139 (4):827-834. Epub 11/08/2018.

Impact of parental asthma, prenatal maternal asthma control, and vitamin D status on risk of asthma and recurrent wheeze in 3-year-old children.

Mirzakhani H, Carey VJ, Zeiger R, Bacharier LB, O'Connor GT, Schatz MX, Laranjo N, Weiss ST, Litonjua AA

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.. 2019 April 49 (4):419-429. Epub 01/03/2019.

Gut microbiota and overweight in 3-year old children.

Karvonen AM, Sordillo JE, Gold DR, Bacharier LB, O'Connor GT, Zeiger RS, Beigelman A, Weiss ST, Litonjua AA

International journal of obesity : journal of the International Association for the Study of Obesity.. 2019 April 43 (4):713-723. Epub 12/19/2018.

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course.

den Dekker HT, Burrows K, Felix JF, Salas LA, Nedeljkovic I, Yao J, Rifas-Shiman SL, Ruiz-Arenas C, Amin N, Bustamante M, DeMeo DL, John Henderson A, Howe CG, Hivert MF, Arfan Ikram M, de Jongste JC, Lahousse L, Mandaviya PR, van Meurs JB, Pinart M, Sharp GC, Stolk L, Uitterlinden AG, Anto JM, Litonjua AA, Breton CV, Brusselle GG, Sunyer J, Smith GD, Relton CL, Jaddoe VWV, Duijts L

The European respiratory journal.. 2019 April 53 (4)Epub 04/04/2019.

Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood.

Cardenas A, Faleschini S, Cortes Hidalgo A, Rifas-Shiman SL, Baccarelli AA, DeMeo DL, Litonjua AA, Neumann A, Felix JF, Jaddoe VWV, El Marroun H, Tiemeier H, Oken E, Hivert MF, Burris HH

Clinical epigenetics.. 2019 March 2911 (1):56. Epub 03/29/2019.

Metabolomics and Communication Skills Development in Children; Evidence from the Ages and Stages Questionnaire.

Kelly RS, Boulin A, Laranjo N, Lee-Sarwar K, Chu SH, Yadama AP, Carey V, Litonjua AA, Lasky-Su J, Weiss ST

Metabolites.. 2019 March 59 (3)Epub 03/05/2019.

Association of the Infant Gut Microbiome With Early Childhood Neurodevelopmental Outcomes: An Ancillary Study to the VDAART Randomized Clinical Trial.

Sordillo JE, Korrick S, Laranjo N, Carey V, Weinstock GM, Gold DR, O'Connor G, Sandel M, Bacharier LB, Beigelman A, Zeiger R, Litonjua AA, Weiss ST

JAMA network open.. 2019 March 12 (3):e190905. Epub 03/01/2019.

Expression network analysis reveals cord blood vitamin D-associated genes affecting risk of early life wheeze.

Mirzakhani H, Al-Garawi AA, Carey VJ, Qiu W, Litonjua AA, Weiss ST

Thorax.. 2019 February 74 (2):200-202. Epub 07/18/2018.

Dietary and Plasma Polyunsaturated Fatty Acids Are Inversely Associated with Asthma and Atopy in Early Childhood.

Lee-Sarwar K, Kelly RS, Lasky-Su J, Kachroo P, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Weiss ST, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2019 February 7 (2):529-538.e8. Epub 08/24/2018.

Impact of Preeclampsia on the Relationship between Maternal Asthma and Offspring Asthma. An Observation from the VDAART Clinical Trial.

Mirzakhani H, Carey VJ, McElrath TF, Qiu W, Hollis BW, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST

American journal of respiratory and critical care medicine.. 2019 January 1199 (1):32-42. Epub 1900 01 01.

Lower perinatal exposure to Proteobacteria is an independent predictor of early childhood wheezing.

Turturice BA, Gold DR, Litonjua AA, Oken E, Rifas-Shiman S, Perkins DL, Finn PW

The Journal of allergy and clinical immunology.. 2019 January 143 (1):419-421.e5. Epub 09/08/2018.

Pollution, Obesity, Vitamin D, or Why Is Asthma So Complicated-and Interesting.

Forno E, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2019 7 (6):1823-1824. Epub 1900 01 01.

Diet during Pregnancy and Infancy and the Infant Intestinal Microbiome.

Savage JH, Lee-Sarwar KA, Sordillo JE, Lange NE, Zhou Y, O'Connor GT, Sandel M, Bacharier LB, Zeiger R, Sodergren E, Weinstock GM, Gold DR, Weiss ST, Litonjua AA

The Journal of pediatrics.. 2018 December 203 :47-54.e4. Epub 08/30/2018.

Partial Least Squares Discriminant Analysis and Bayesian Networks for Metabolomic Prediction of Childhood Asthma.

Kelly RS, McGeachie MJ, Lee-Sarwar KA, Kachroo P, Chu SH, Virkud YV, Huang M, Litonjua AA, Weiss ST, Lasky-Su J

Metabolites.. 2018 October 238 (4)Epub 10/23/2018.

Longitudinal Modeling of Lung Function Trajectories in Smokers with and without Chronic Obstructive Pulmonary Disease.

Ross JC, Castaldi PJ, Cho MH, Hersh CP, Rahaghi FN, Sánchez-Ferrero GV, Parker MM, Litonjua AA, Sparrow D, Dy JG, Silverman EK, Washko GR, San José Estépar R

American journal of respiratory and critical care medicine.. 2018 October 15198 (8):1033-1042. Epub 1900 01 01.

Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations.

Ho NT, Li F, Lee-Sarwar KA, Tun HM, Brown BP, Pannaraj PS, Bender JM, Azad MB, Thompson AL, Weiss ST, Azcarate-Peril MA, Litonjua AA, Kozyrskyj AL, Jaspan HB, Aldrovandi GM, Kuhn L

Nature communications.. 2018 October 99 (1):4169. Epub 10/09/2018.

Plasma metabolite profiles in children with current asthma.

Kelly RS, Sordillo JE, Lasky-Su J, Dahlin A, Perng W, Rifas-Shiman SL, Weiss ST, Gold DR, Litonjua AA, Hivert MF, Oken E, Wu AC

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.. 2018 October 48 (10):1297-1304. Epub 07/03/2018.

Observational studies of vitamin D associations with asthma: Problems and pitfalls.

Bashir A, Litonjua AA

Pediatric pulmonology.. 2018 October 53 (10):1338-1339. Epub 07/12/2018.

The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma.

Dahlin A, Qiu W, Litonjua AA, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Wu AC, Weiss ST, Tantisira KG

The pharmacogenomics journal.. 2018 September 18 (5):665-677. Epub 01/03/2018.

Residential Proximity to Major Roadways at Birth, DNA Methylation at Birth and Midchildhood, and Childhood Cognitive Test Scores: Project Viva(Massachusetts, USA).

Peng C, den Dekker M, Cardenas A, Rifas-Shiman SL, Gibson H, Agha G, Harris MH, Coull BA, Schwartz J, Litonjua AA, DeMeo DL, Hivert MF, Gilman MW, Sagiv SK, de Kluizenaar Y, Felix JF, Jaddoe VW, Oken E, Duijts L, Gold DR, Baccarelli AA

Environmental health perspectives.. 2018 September 126 (9):97006. Epub 1900 01 01.

Lung function association with outdoor temperature and relative humidity and its interaction with air pollution in the elderly.

Lepeule J, Litonjua AA, Gasparrini A, Koutrakis P, Sparrow D, Vokonas PS, Schwartz J

Environmental research.. 2018 August 165 :110-117. Epub 04/21/2018.

Relation of Prenatal Air Pollutant and Nutritional Exposures with Biomarkers of Allergic Disease in Adolescence.

Sordillo JE, Switkowski KM, Coull BA, Schwartz J, Kloog I, Gibson H, Litonjua AA, Bobb J, Koutrakis P, Rifas-Shiman SL, Oken E, Gold DR

Scientific reports.. 2018 July 128 (1):10578. Epub 07/12/2018.

Prenatal and early-life triclosan and paraben exposure and allergic outcomes.

Lee-Sarwar K, Hauser R, Calafat AM, Ye X, O'Connor GT, Sandel M, Bacharier LB, Zeiger RS, Laranjo N, Gold DR, Weiss ST, Litonjua AA, Savage JH

The Journal of allergy and clinical immunology.. 2018 July 142 (1):269-278.e15. Epub 10/27/2017.

Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy.

Lee-Sarwar K, Kelly RS, Lasky-Su J, Moody DB, Mola AR, Cheng TY, Comstock LE, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Bunyavanich S, Savage JH, Weiss ST, Brennan PJ, Litonjua AA

The Journal of allergy and clinical immunology.. 2018 July 142 (1):335-338.e9. Epub 05/02/2018.

Lifetime air pollution exposure and asthma in a pediatric birth cohort.

Rice MB, Rifas-Shiman SL, Litonjua AA, Gillman MW, Liebman N, Kloog I, Luttmann-Gibson H, Coull BA, Schwartz J, Koutrakis P, Oken E, Mittleman MA, Gold DR

The Journal of allergy and clinical immunology.. 2018 May 141 (5):1932-1934.e7. Epub 02/02/2018.

Folic Acid in Pregnancy and Childhood Asthma: A US Cohort.

Trivedi MK, Sharma S, Rifas-Shiman SL, Camargo CA, Weiss ST, Oken E, Gillman MW, Gold DR, DeMeo DL, Litonjua AA

Clinical pediatrics.. 2018 April 57 (4):421-427. Epub 09/08/2017.

Prenatal and Early Life Fructose, Fructose-Containing Beverages, and Midchildhood Asthma.

Wright LS, Rifas-Shiman SL, Oken E, Litonjua AA, Gold DR

Annals of the American Thoracic Society.. 2018 February 15 (2):217-224. Epub 1900 01 01.

Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial.

Hornsby E, Pfeffer PE, Laranjo N, Cruikshank W, Tuzova M, Litonjua AA, Weiss ST, Carey VJ, O'Connor G, Hawrylowicz C

The Journal of allergy and clinical immunology.. 2018 January 141 (1):269-278.e1. Epub 05/26/2017.

A prospective microbiome-wide association study of food sensitization and food allergy in early childhood.

Savage JH, Lee-Sarwar KA, Sordillo J, Bunyavanich S, Zhou Y, O'Connor G, Sandel M, Bacharier LB, Zeiger R, Sodergren E, Weinstock GM, Gold DR, Weiss ST, Litonjua AA

Allergy.. 2018 January 73 (1):145-152. Epub 08/02/2017.

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts.

Sharp GC, Arathimos R, Reese SE, Page CM, Felix J, Küpers LK, Rifas-Shiman SL, Liu C, , Burrows K, Zhao S, Magnus MC, Duijts L, Corpeleijn E, DeMeo DL, Litonjua A, Baccarelli A, Hivert MF, Oken E, Snieder H, Jaddoe V, Nystad W, London SJ, Relton CL, Zuccolo L

Epigenomics.. 2018 January 10 (1):27-42. Epub 11/27/2017.

The Association of Maternal Asthma and Early Pregnancy Vitamin D with Risk of Preeclampsia: An Observation From Vitamin D Antenatal Asthma Reduction Trial (VDAART).

Mirzakhani H, Carey VJ, McElrath TF, Laranjo N, O'Connor G, Iverson RE, Lee-Parritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Litonjua AA, Weiss ST

The journal of allergy and clinical immunology. In practice.. 2018 6 (2):600-608.e2. Epub 09/08/2017.

As You Eat It: Effects of Prenatal Nutrition on Asthma.

Lee-Sarwar K, Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2018 6 (3):711-718. Epub 02/02/2018.

Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach.

Peng C, Cardenas A, Rifas-Shiman SL, Hivert MF, Gold DR, Platts-Mills TA, Lin X, Oken E, Baccarelli AA, Litonjua AA, DeMeo DL

Clinical epigenetics.. 2018 10 :55. Epub 04/17/2018.

Can a Diet with Low Proinflammatory Potential Help with Asthma?

Litonjua AA

The journal of allergy and clinical immunology. In practice.. 2018 6 (3):842-843. Epub 1900 01 01.

Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts.

Carmona JJ, Barfield RT, Panni T, Nwanaji-Enwerem JC, Just AC, Hutchinson JN, Colicino E, Karrasch S, Wahl S, Kunze S, Jafari N, Zheng Y, Hou L, DeMeo DL, Litonjua AA, Vokonas PS, Peters A, Lin X, Schwartz J, Schulz H, Baccarelli AA

Epigenetics.. 2018 13 (10-11):1039-1055. Epub 10/21/2018.

DNA methylation in blood as a mediator of the association of mid-childhood body mass index with cardio-metabolic risk score in early adolescence.

Huang JV, Cardenas A, Colicino E, Schooling CM, Rifas-Shiman SL, Agha G, Zheng Y, Hou L, Just AC, Litonjua AA, DeMeo DL, Lin X, Oken E, Hivert MF, Baccarelli AA

Epigenetics.. 2018 13 (10-11):1072-1087. Epub 11/13/2018.

Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from the Vitamin D Antenatal Asthma Reduction Trial.

Wolsk HM, Harshfield BJ, Laranjo N, Carey VJ, O'Connor G, Sandel M, Strunk RC, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2017 November 140 (5):1423-1429.e5. Epub 03/09/2017.

Asthma control status in pregnancy, body mass index, and maternal vitamin D levels.

Mirzakhani H, O'Connor G, Bacharier LB, Zeiger RS, Schatz MX, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2017 November 140 (5):1453-1456.e7. Epub 06/09/2017.

Genome-wide interaction study of dust mite allergen on lung function in children with asthma.

Forno E, Sordillo J, Brehm J, Chen W, Benos T, Yan Q, Avila L, Soto-Quirós M, Cloutier MM, Colón-Semidey A, Alvarez M, Acosta-Pérez E, Weiss ST, Litonjua AA, Canino G, Celedón JC

The Journal of allergy and clinical immunology.. 2017 October 140 (4):996-1003.e7. Epub 02/04/2017.

Perinatal Bacterial Exposure Contributes to IL-13 Aeroallergen Response.

Turturice BA, Ranjan R, Nguyen B, Hughes LM, Andropolis KE, Gold DR, Litonjua AA, Oken E, Perkins DL, Finn PW

American journal of respiratory cell and molecular biology.. 2017 October 57 (4):419-427. Epub 1900 01 01.

Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y.

Blighe K, Chawes BL, Kelly RS, Mirzakhani H, McGeachie M, Litonjua AA, Weiss ST, Lasky-Su JA

The American journal of clinical nutrition.. 2017 October 106 (4):1092-1099. Epub 08/23/2017.

Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility.

Radder JE, Gregory AD, Leme AS, Cho MH, Chu Y, Kelly NJ, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Beaty TH, Crapo JD, Silverman EK, Zhang Y, Berndt A, Shapiro SD

American journal of respiratory cell and molecular biology.. 2017 September 57 (3):367-375. Epub 1900 01 01.

Prenatal Exposure to Mercury: Associations with Global DNA Methylation and Hydroxymethylation in Cord Blood and in Childhood.

Cardenas A, Rifas-Shiman SL, Godderis L, Duca RC, Navas-Acien A, Litonjua AA, DeMeo DL, Brennan KJ, Amarasiriwardena CJ, Hivert MF, Gillman MW, Oken E, Baccarelli AA

Environmental health perspectives.. 2017 August 29125 (8):087022. Epub 08/29/2017.

Exposure to Low Levels of Lead and Umbilical Cord Blood DNA Methylation in Project Viva: An Epigenome-Wide Association Study.

Wu S, Hivert MF, Cardenas A, Zhong J, Rifas-Shiman SL, Agha G, Colicino E, Just AC, Amarasiriwardena C, Lin X, Litonjua AA, DeMeo DL, Gillman MW, Wright RO, Oken E, Baccarelli AA

Environmental health perspectives.. 2017 August 25125 (8):087019. Epub 08/25/2017.

Metabolome alterations in severe critical illness and vitamin D status.

Lasky-Su J, Dahlin A, Litonjua AA, Rogers AJ, McGeachie MJ, Baron RM, Gazourian L, Barragan-Bradford D, Fredenburgh LE, Choi AMK, Mogensen KM, Quraishi SA, Amrein K, Christopher KB

Critical care : the official journal of the Critical Care Forum.. 2017 July 2821 (1):193. Epub 07/28/2017.

Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.

Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Tal-Singer R, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Paré PD, Levy RD, Rennard SI, Beaty TH, Hokanson J, Silverman EK, Cho MH, , , , ,

American journal of respiratory cell and molecular biology.. 2017 July 57 (1):35-46. Epub 1900 01 01.

Low Maternal Prenatal 25-Hydroxyvitamin D Blood Levels Are Associated with Childhood Atopic Dermatitis.

Blomberg M, Rifas-Shiman SL, Camargo CA, Gold DR, Asgari MM, Thyssen JP, Litonjua AA, Gillman MW, Oken E

The Journal of investigative dermatology.. 2017 June 137 (6):1380-1384. Epub 02/12/2017.

Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma.

Farahi N, Paige E, Balla J, Prudence E, Ferreira RC, Southwood M, Appleby SL, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Silverman EK, Cho MH, Danesh J, Paul DS, Freitag DF, Chilvers ER

Human molecular genetics.. 2017 April 1526 (8):1584-1596. Epub 1900 01 01.

Persistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood.

Cardenas A, Rifas-Shiman SL, Agha G, Hivert MF, Litonjua AA, DeMeo DL, Lin X, Amarasiriwardena CJ, Oken E, Gillman MW, Baccarelli AA

Scientific reports.. 2017 March 217 (1):288. Epub 03/21/2017.

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP, , Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL, , Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho MH, Silverman EK, Sayers I, Trynka G, Morris AP, Strachan DP, Hall IP, Tobin MD

Nature genetics.. 2017 March 49 (3):416-425. Epub 02/06/2017.

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH, , , , , , ,

Nature genetics.. 2017 March 49 (3):426-432. Epub 02/06/2017.

Obesity and Airway Dysanapsis in Children with and without Asthma.

Forno E, Weiner DJ, Mullen J, Sawicki G, Kurland G, Han YY, Cloutier MM, Canino G, Weiss ST, Litonjua AA, Celedón JC

American journal of respiratory and critical care medicine.. 2017 February 1195 (3):314-323. Epub 1900 01 01.

Factors influencing the infant gut microbiome at age 3-6 months: Findings from the ethnically diverse Vitamin D Antenatal Asthma Reduction Trial (VDAART).

Sordillo JE, Zhou Y, McGeachie MJ, Ziniti J, Lange N, Laranjo N, Savage JR, Carey V, O'Connor G, Sandel M, Strunk R, Bacharier L, Zeiger R, Weiss ST, Weinstock G, Gold DR, Litonjua AA

The Journal of allergy and clinical immunology.. 2017 February 139 (2):482-491.e14. Epub 10/13/2016.

Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia.

Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA

Metabolomics : Official journal of the Metabolomic Society.. 2017 January 13 (1)Epub 12/12/2016.

Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials.

Wolsk HM, Chawes BL, Litonjua AA, Hollis BW, Waage J, Stokholm J, Bønnelykke K, Bisgaard H, Weiss ST

PloS one.. 2017 12 (10):e0186657. Epub 10/27/2017.

Early pregnancy vitamin D status and risk of preeclampsia.

Mirzakhani H, Litonjua AA, McElrath TF, O'Connor G, Lee-Parritz A, Iverson R, Macones G, Strunk RC, Bacharier LB, Zeiger R, Hollis BW, Handy DE, Sharma A, Laranjo N, Carey V, Qiu W, Santolini M, Liu S, Chhabra D, Enquobahrie DA, Williams MA, Loscalzo J, Weiss ST

The Journal of clinical investigation.. 2016 December 1126 (12):4702-4715. Epub 11/14/2016.

Sex-specific risk factors for childhood wheeze and longitudinal phenotypes of wheeze.

Tse SM, Rifas-Shiman SL, Coull BA, Litonjua AA, Oken E, Gold DR

The Journal of allergy and clinical immunology.. 2016 December 138 (6):1561-1568.e6. Epub 04/27/2016.

Vitamin D and bronchopulmonary dysplasia in preterm infants.

Joung KE, Burris HH, Van Marter LJ, McElrath TF, Michael Z, Tabatabai P, Litonjua AA, Weiss ST, Christou H

Journal of perinatology : official journal of the California Perinatal Association.. 2016 October 36 (10):878-82. Epub 07/28/2016.

Lifetime Exposure to Ambient Pollution and Lung Function in Children.

Rice MB, Rifas-Shiman SL, Litonjua AA, Oken E, Gillman MW, Kloog I, Luttmann-Gibson H, Zanobetti A, Coull BA, Schwartz J, Koutrakis P, Mittleman MA, Gold DR

American journal of respiratory and critical care medicine.. 2016 April 15193 (8):881-8. Epub 1900 01 01.

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Håberg SE, Xu Z, van Meurs JB, Gaunt TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergström A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles MA, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert MF, Eskenazi B, Vrijheid M, Arshad H, Antó JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VW, Wilcox A, Melén E, London SJ

American journal of human genetics.. 2016 April 798 (4):680-96. Epub 03/31/2016.

Increases in pre-hospitalization serum 25(OH)D concentrations are associated with improved 30-day mortality after hospital admission: A cohort study.

Amrein K, Litonjua AA, Moromizato T, Quraishi SA, Gibbons FK, Pieber TR, Camargo CA, Giovannucci E, Christopher KB

Clinical nutrition : official journal of the European Society of Parenteral and Enteral Nutrition.. 2016 April 35 (2):514-521. Epub 04/14/2015.

Genome-wide association study of leukotriene modifier response in asthma.

Dahlin A, Litonjua A, Irvin CG, Peters SP, Lima JJ, Kubo M, Tamari M, Tantisira KG

The pharmacogenomics journal.. 2016 April 16 (2):151-7. Epub 06/02/2015.

Prenatal, perinatal, and childhood vitamin D exposure and their association with childhood allergic rhinitis and allergic sensitization.

Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Camargo CA, Gillman MW, Gold DR, Litonjua AA

The Journal of allergy and clinical immunology.. 2016 April 137 (4):1063-1070.e2. Epub 02/10/2016.

Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults.

Gold DR, Litonjua AA, Carey VJ, Manson JE, Buring JE, Lee IM, Gordon D, Walter J, Friedenberg G, Hankinson JL, Copeland T, Luttmann-Gibson H

Contemporary clinical trials.. 2016 March 47 :185-95. Epub 01/16/2016.

Longitudinal Prediction of the Infant Gut Microbiome with Dynamic Bayesian Networks.

McGeachie MJ, Sordillo JE, Gibson T, Weinstock GM, Liu YY, Gold DR, Weiss ST, Litonjua A

Scientific reports.. 2016 February 86 :20359. Epub 02/08/2016.

Serum tocopherol levels and vitamin E intake are associated with lung function in the normative aging study.

Hanson C, Lyden E, Furtado J, Campos H, Sparrow D, Vokonas P, Litonjua AA

Clinical nutrition : official journal of the European Society of Parenteral and Enteral Nutrition.. 2016 February 35 (1):169-174. Epub 02/07/2015.

Folate Deficiency, Atopy, and Severe Asthma Exacerbations in Puerto Rican Children.

Blatter J, Brehm JM, Sordillo J, Forno E, Boutaoui N, Acosta-Pérez E, Alvarez M, Colón-Semidey A, Weiss ST, Litonjua AA, Canino G, Celedón JC

Annals of the American Thoracic Society.. 2016 February 13 (2):223-30. Epub 1900 01 01.

Dietary anthocyanin intake and age-related decline in lung function: longitudinal findings from the VA Normative Aging Study.

Mehta AJ, Cassidy A, Litonjua AA, Sparrow D, Vokonas P, Schwartz J

The American journal of clinical nutrition.. 2016 February 103 (2):542-50. Epub 01/20/2016.

Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial.

Litonjua AA, Carey VJ, Laranjo N, Harshfield BJ, McElrath TF, O'Connor GT, Sandel M, Iverson RE, Lee-Paritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Hornsby E, Hawrylowicz C, Wu AC, Weiss ST

JAMA.. 2016 January 26315 (4):362-70. Epub 1900 01 01.

The Role of Vitamin D in the Transcriptional Program of Human Pregnancy.

Al-Garawi A, Carey VJ, Chhabra D, Mirzakhani H, Morrow J, Lasky-Su J, Qiu W, Laranjo N, Litonjua AA, Weiss ST

PloS one.. 2016 11 (10):e0163832. Epub 10/06/2016.

Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood.

Agha G, Hajj H, Rifas-Shiman SL, Just AC, Hivert MF, Burris HH, Lin X, Litonjua AA, Oken E, DeMeo DL, Gillman MW, Baccarelli AA

Clinical epigenetics.. 2016 8 :118. Epub 11/16/2016.

Genome-wide expression profiles identify potential targets for gene-environment interactions in asthma severity.

Sordillo JE, Kelly R, Bunyavanich S, McGeachie M, Qiu W, Croteau-Chonka DC, Soto-Quiros M, Avila L, Celedón JC, Brehm JM, Weiss ST, Gold DR, Litonjua AA

The Journal of allergy and clinical immunology.. 2015 October 136 (4):885-92.e2. Epub 04/24/2015.

Diet, interleukin-17, and childhood asthma in Puerto Ricans.

Han YY, Forno E, Brehm JM, Acosta-Pérez E, Alvarez M, Colón-Semidey A, Rivera-Soto W, Campos H, Litonjua AA, Alcorn JF, Canino G, Celedón JC

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.. 2015 October 115 (4):288-293.e1. Epub 08/28/2015.

A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma.

Brehm JM, Man Tse S, Croteau-Chonka DC, Forno E, Litonjua AA, Raby BA, Chen W, Yan Q, Boutaoui N, Acosta-Pérez E, Avila L, Weiss ST, Soto-Quiros M, Cloutier MM, Hu D, Pino-Yanes M, Wenzel SE, Spear ML, Kolls JK, Burchard EG, Canino G, Celedón JC

American journal of respiratory and critical care medicine.. 2015 September 1192 (5):634-7. Epub 1900 01 01.

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease.

Hansel NN, Paré PD, Rafaels N, Sin DD, Sandford A, Daley D, Vergara C, Huang L, Elliott WM, Pascoe CD, Arsenault BA, Postma DS, Boezen HM, Bossé Y, van den Berge M, Hiemstra PS, Cho MH, Litonjua AA, Sparrow D, Ober C, Wise RA, Connett J, Neptune ER, Beaty TH, Ruczinski I, Mathias RA, Barnes KC,

American journal of respiratory cell and molecular biology.. 2015 August 53 (2):226-34. Epub 1900 01 01.

Measuring the corticosteroid responsiveness endophenotype in asthmatic patients.

Clemmer GL, Wu AC, Rosner B, McGeachie MJ, Litonjua AA, Tantisira KG, Weiss ST

The Journal of allergy and clinical immunology.. 2015 August 136 (2):274-81.e8. Epub 05/05/2015.

Stress and Bronchodilator Response in Children with Asthma.

Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, Colón-Semidey A, Alvarez M, Acosta-Pérez E, Spear ML, Martinez FD, Avila L, Weiss ST, Soto-Quiros M, Ober C, Nicolae DL, Barnes KC, Lemanske RF, Strunk RC, Liu A, London SJ, Gilliland F, Sleiman P, March M, Hakonarson H, Duan QL, Kolls JK, Fritz GK, Hu D, Fani N, Stevens JS, Almli LM, Burchard EG, Shin J, McQuaid EL, Ressler K, Canino G, Celedón JC

American journal of respiratory and critical care medicine.. 2015 July 1192 (1):47-56. Epub 1900 01 01.

Association between pre-hospital vitamin D status and hospital-acquired new-onset delirium.

Quraishi SA, Litonjua AA, Elias KM, Gibbons FK, Giovannucci E, Camargo CA, Christopher KB

The British journal of nutrition.. 2015 June 14113 (11):1753-60. Epub 1900 01 01.

Exposure to traffic and early life respiratory infection: A cohort study.

Rice MB, Rifas-Shiman SL, Oken E, Gillman MW, Ljungman PL, Litonjua AA, Schwartz J, Coull BA, Zanobetti A, Koutrakis P, Melly SJ, Mittleman MA, Gold DR

Pediatric pulmonology.. 2015 March 50 (3):252-259. Epub 03/27/2014.

Cohort profile: project viva.

Oken E, Baccarelli AA, Gold DR, Kleinman KP, Litonjua AA, De Meo D, Rich-Edwards JW, Rifas-Shiman SL, Sagiv S, Taveras EM, Weiss ST, Belfort MB, Burris HH, Camargo CA, Huh SY, Mantzoros C, Parker MG, Gillman MW

International journal of epidemiology.. 2015 February 44 (1):37-48. Epub 03/16/2014.

Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children.

Sordillo JE, Scirica CV, Rifas-Shiman SL, Gillman MW, Bunyavanich S, Camargo CA, Weiss ST, Gold DR, Litonjua AA

The Journal of allergy and clinical immunology.. 2015 February 135 (2):441-8. Epub 10/28/2014.

Association between prehospital vitamin D status and hospital-acquired Clostridium difficile infections.

Quraishi SA, Litonjua AA, Moromizato T, Gibbons FK, Camargo CA, Giovannucci E, Christopher KB

JPEN. Journal of parenteral and enteral nutrition.. 2015 January 39 (1):47-55. Epub 02/03/2014.

Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma.

Dahlin A, Litonjua A, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Tantisira KG

PloS one.. 2015 10 (6):e0129385. Epub 06/17/2015.

Association between prehospital vitamin D status and incident acute respiratory failure in critically ill patients: a retrospective cohort study.

Thickett DR, Moromizato T, Litonjua AA, Amrein K, Quraishi SA, Lee-Sarwar KA, Mogensen KM, Purtle SW, Gibbons FK, Camargo CA, Giovannucci E, Christopher KB

BMJ open respiratory research.. 2015 2 (1):e000074. Epub 06/13/2015.

Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma.

Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA, Weiss ST

PloS one.. 2015 10 (7):e0134057. Epub 07/24/2015.

Long-term effects of traffic particles on lung function decline in the elderly.

Lepeule J, Litonjua AA, Coull B, Koutrakis P, Sparrow D, Vokonas PS, Schwartz J

American journal of respiratory and critical care medicine.. 2014 September 1190 (5):542-8. Epub 1900 01 01.

Peanut allergy prevalence among school-age children in a US cohort not selected for any disease.

Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Gillman MW, Gold DR, Litonjua AA

The Journal of allergy and clinical immunology.. 2014 September 134 (3):753-5. Epub 07/30/2014.

Variants of asthma and chronic obstructive pulmonary disease genes and lung function decline in aging.

Poon AH, Houseman EA, Ryan L, Sparrow D, Vokonas PS, Litonjua AA

The journals of gerontology. Series A, Biological sciences and medical sciences.. 2014 July 69 (7):907-13. Epub 11/19/2013.

Epigenetic influences on associations between air pollutants and lung function in elderly men: the normative aging study.

Lepeule J, Bind MA, Baccarelli AA, Koutrakis P, Tarantini L, Litonjua A, Sparrow D, Vokonas P, Schwartz JD

Environmental health perspectives.. 2014 June 122 (6):566-72. Epub 03/06/2014.

Peanut, milk, and wheat intake during pregnancy is associated with reduced allergy and asthma in children.

Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Camargo CA, Gillman MW, Gold DR, Litonjua AA

The Journal of allergy and clinical immunology.. 2014 May 133 (5):1373-82. Epub 02/09/2014.

The Vitamin D Antenatal Asthma Reduction Trial (VDAART): rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for the primary prevention of asthma and allergies in children.

Litonjua AA, Lange NE, Carey VJ, Brown S, Laranjo N, Harshfield BJ, O'Connor GT, Sandel M, Strunk RC, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST

Contemporary clinical trials.. 2014 May 38 (1):37-50. Epub 03/12/2014.

Vitamin D status and hypertensive disorders in pregnancy.

Burris HH, Rifas-Shiman SL, Huh SY, Kleinman K, Litonjua AA, Oken E, Rich-Edwards JW, Camargo CA, Gillman MW

Annals of epidemiology.. 2014 May 24 (5):399-403.e1. Epub 02/15/2014.

The association between asthma and allergic disease and mortality: a 30-year follow-up study.

Savage JH, Matsui EC, McCormack M, Litonjua AA, Wood RA, Keet CA

The Journal of allergy and clinical immunology.. 2014 May 133 (5):1484-7, 1487.e1-5. Epub 03/14/2014.

Statin use in asthmatics on inhaled corticosteroids is associated with decreased risk of emergency department visits.

Tse SM, Charland SL, Stanek E, Herrera V, Goldfarb S, Litonjua AA, Weiss ST, Wu AC

Current medical research and opinion.. 2014 April 30 (4):685-93. Epub 12/18/2013.

Evidence for a U-shaped relationship between prehospital vitamin D status and mortality: a cohort study.

Amrein K, Quraishi SA, Litonjua AA, Gibbons FK, Pieber TR, Camargo CA, Giovannucci E, Christopher KB

The Journal of clinical endocrinology and metabolism.. 2014 April 99 (4):1461-9. Epub 01/13/2014.

Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.

Wu AC, Himes BE, Lasky-Su J, Litonjua A, Peters SP, Lima J, Kubo M, Tamari M, Nakamura Y, Qiu W, Weiss ST, Tantisira K

The Journal of allergy and clinical immunology.. 2014 March 133 (3):723-8.e3. Epub 11/23/2013.

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.

Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH,

The Lancet. Respiratory medicine.. 2014 March 2 (3):214-25. Epub 02/07/2014.

A genome-wide association study of bronchodilator response in asthmatics.

Duan QL, Lasky-Su J, Himes BE, Qiu W, Litonjua AA, Damask A, Lazarus R, Klanderman B, Irvin CG, Peters SP, Hanrahan JP, Lima JJ, Martinez FD, Mauger D, Chinchilli VM, Soto-Quiros M, Avila L, Celedón JC, Lange C, Weiss ST, Tantisira KG

The pharmacogenomics journal.. 2014 February 14 (1):41-7. Epub 03/19/2013.

Urinary triclosan levels and recent asthma exacerbations.

Savage JH, Johns CB, Hauser R, Litonjua AA

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.. 2014 February 112 (2):179-181.e2. Epub 12/15/2013.

Association of low serum 25-hydroxyvitamin D levels and sepsis in the critically ill.

Moromizato T, Litonjua AA, Braun AB, Gibbons FK, Giovannucci E, Christopher KB

Critical care medicine.. 2014 January 42 (1):97-107. Epub 1900 01 01.

Vitamin D status among preterm and full-term infants at birth.

Burris HH, Van Marter LJ, McElrath TF, Tabatabai P, Litonjua AA, Weiss ST, Christou H

Pediatric research.. 2014 January 75 (1-1):75-80. Epub 10/11/2013.

Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease.

Aminuddin F, Hackett TL, Stefanowicz D, Saferali A, Paré PD, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Silverman EK, Sandford AJ

BMC pulmonary medicine.. 2013 November 613 :64. Epub 11/06/2013.

Association between prehospital vitamin D status and hospital-acquired bloodstream infections.

Quraishi SA, Litonjua AA, Moromizato T, Gibbons FK, Camargo CA, Giovannucci E, Christopher KB

The American journal of clinical nutrition.. 2013 October 98 (4):952-9. Epub 08/14/2013.

Diagnostic accuracy of the bronchodilator response in children.

Tse SM, Gold DR, Sordillo JE, Hoffman EB, Gillman MW, Rifas-Shiman SL, Fuhlbrigge AL, Tantisira KG, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2013 September 132 (3):554-559.e5. Epub 05/14/2013.

Pre-hospital vitamin D concentration, mortality, and bloodstream infection in a hospitalized patient population.

Lange N, Litonjua AA, Gibbons FK, Giovannucci E, Christopher KB

The American journal of medicine.. 2013 July 126 (7):640.e19-27. Epub 1900 01 01.

Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells.

Zhou X, Qiu W, Sathirapongsasuti JF, Cho MH, Mancini JD, Lao T, Thibault DM, Litonjua AA, Bakke PS, Gulsvik A, Lomas DA, Beaty TH, Hersh CP, Anderson C, Geigenmuller U, Raby BA, Rennard SI, Perrella MA, Choi AM, Quackenbush J, Silverman EK

Genomics.. 2013 May 101 (5):263-72. Epub 03/01/2013.

A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics.

Duan QL, Du R, Lasky-Su J, Klanderman BJ, Partch AB, Peters SP, Irvin CG, Hanrahan JP, Lima JJ, Blake KV, Liggett SB, Litonjua AA, Tantisira KG

The pharmacogenomics journal.. 2013 April 13 (2):130-6. Epub 01/03/2012.

Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.

Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Lange C, Silverman EK,

Human genetics.. 2013 April 132 (4):431-41. Epub 01/09/2013.

Allergen sensitization is associated with increased DNA methylation in older men.

Sordillo JE, Lange NE, Tarantini L, Bollati V, Zanobetti A, Sparrow D, Vokonas P, Schwartz J, Baccarelli A, Demeo D, Litonjua AA

International archives of allergy and immunology.. 2013 161 (1):37-43. Epub 12/14/2012.

Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.

Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST

PloS one.. 2013 8 (2):e56179. Epub 02/14/2013.

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.

Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustí A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, Rennard S, Litonjua A, Qiu W, Beaty TH, Crapo JD, Riley JH, Tal-Singer R, Silverman EK,

American journal of respiratory and critical care medicine.. 2012 December 15186 (12):1238-47. Epub 11/09/2012.

Association of low serum 25-hydroxyvitamin D levels and acute kidney injury in the critically ill.

Braun AB, Litonjua AA, Moromizato T, Gibbons FK, Giovannucci E, Christopher KB

Critical care medicine.. 2012 December 40 (12):3170-9. Epub 1900 01 01.

Vitamin D deficiency, smoking, and lung function in the Normative Aging Study.

Lange NE, Sparrow D, Vokonas P, Litonjua AA

American journal of respiratory and critical care medicine.. 2012 October 1186 (7):616-21. Epub 07/19/2012.

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, Henry AP, Aldrich M, Bakke P, Beaty TH, Bentley AR, Borecki IB, Brusselle GG, Burkart KM, Chen TH, Couper D, Crapo JD, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock DB, Harris TB, Hofman A, Imboden M, James AL, Khaw KT, Lahousse L, Launer LJ, Litonjua A, Liu Y, Lohman KK, Lomas DA, Lumley T, Marciante KD, McArdle WL, Meibohm B, Morrison AC, Musk AW, Myers RH, North KE, Postma DS, Psaty BM, Rich SS, Rivadeneira F, Rochat T, Rotter JI, Soler Artigas M, Starr JM, Uitterlinden AG, Wareham NJ, Wijmenga C, Zanen P, Province MA, Silverman EK, Deary IJ, Palmer LJ, Cassano PA, Gudnason V, Barr RG, Loos RJ, Strachan DP, London SJ, Boezen HM, Probst-Hensch N, Gharib SA, Hall IP, O'Connor GT, Tobin MD, Stricker BH

American journal of respiratory and critical care medicine.. 2012 October 1186 (7):622-32. Epub 07/26/2012.

Effect of vitamin D and inhaled corticosteroid treatment on lung function in children.

Wu AC, Tantisira K, Li L, Fuhlbrigge AL, Weiss ST, Litonjua A,

American journal of respiratory and critical care medicine.. 2012 September 15186 (6):508-13. Epub 07/12/2012.

Genome-wide association analysis of circulating vitamin D levels in children with asthma.

Lasky-Su J, Lange N, Brehm JM, Damask A, Soto-Quiros M, Avila L, Celedón JC, Canino G, Cloutier MM, Hollis BW, Weiss ST, Litonjua AA

Human genetics.. 2012 September 131 (9):1495-505. Epub 06/07/2012.

Vitamin D deficiency in pregnancy and gestational diabetes mellitus.

Burris HH, Rifas-Shiman SL, Kleinman K, Litonjua AA, Huh SY, Rich-Edwards JW, Camargo CA, Gillman MW

American journal of obstetrics and gynecology.. 2012 September 207 (3):182.e1-8. Epub 06/01/2012.

Plasma 25-hydroxyvitamin D during pregnancy and small-for-gestational age in black and white infants.

Burris HH, Rifas-Shiman SL, Camargo CA, Litonjua AA, Huh SY, Rich-Edwards JW, Gillman MW

Annals of epidemiology.. 2012 August 22 (8):581-6. Epub 06/01/2012.

Vitamin D insufficiency and severe asthma exacerbations in Puerto Rican children.

Brehm JM, Acosta-Pérez E, Klei L, Roeder K, Barmada M, Boutaoui N, Forno E, Kelly R, Paul K, Sylvia J, Litonjua AA, Cabana M, Alvarez M, Colón-Semidey A, Canino G, Celedón JC

American journal of respiratory and critical care medicine.. 2012 July 15186 (2):140-6. Epub 05/31/2012.

Genetic association between human chitinases and lung function in COPD.

Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, Silverman EK, Sandford AJ

Human genetics.. 2012 July 131 (7):1105-14. Epub 12/28/2011.

Corticosteroid use and bone mineral accretion in children with asthma: effect modification by vitamin D.

Tse SM, Kelly HW, Litonjua AA, Van Natta ML, Weiss ST, Tantisira KG,

The Journal of allergy and clinical immunology.. 2012 July 130 (1):53-60.e4. Epub 05/16/2012.

Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males.

Wernimont SM, Clark AG, Stover PJ, Wells MT, Litonjua AA, Weiss ST, Gaziano JM, Vokonas PS, Tucker KL, Cassano PA

The Journal of nutrition.. 2012 July 142 (7):1272-9. Epub 05/30/2012.

Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.

Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST

PLoS genetics.. 2012 July 8 (7):e1002824. Epub 07/05/2012.

Association of variants in innate immune genes with asthma and eczema.

Sharma S, Poon A, Himes BE, Lasky-Su J, Sordillo JE, Belanger K, Milton DK, Bracken MB, Triche EW, Leaderer BP, Gold DR, Litonjua AA

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.. 2012 June 23 (4):315-23. Epub 12/23/2011.

African ancestry and lung function in Puerto Rican children.

Brehm JM, Acosta-Pérez E, Klei L, Roeder K, Barmada MM, Boutaoui N, Forno E, Cloutier MM, Datta S, Kelly R, Paul K, Sylvia J, Calvert D, Thornton-Thompson S, Wakefield D, Litonjua AA, Alvarez M, Colón-Semidey A, Canino G, Celedón JC

The Journal of allergy and clinical immunology.. 2012 June 129 (6):1484-90.e6. Epub 05/04/2012.

Associations of LINE-1 DNA Methylation with Preterm Birth in a Prospective Cohort Study.

Burris HH, Rifas-Shiman SL, Baccarelli A, Tarantini L, Boeke CE, Kleinman K, Litonjua AA, Rich-Edwards JW, Gillman MW

Journal of developmental origins of health and disease.. 2012 June 3 (3):173-181. Epub 1900 01 01.

Maternal intestinal flora and wheeze in early childhood.

Lange NE, Celedón JC, Forno E, Ly NP, Onderdonk A, Bry L, Delaney ML, DuBois AM, Gold DR, Weiss ST, Litonjua AA

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.. 2012 June 42 (6):901-8. Epub 1900 01 01.

Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: prospective results from a folate-replete population.

Boeke CE, Baccarelli A, Kleinman KP, Burris HH, Litonjua AA, Rifas-Shiman SL, Tarantini L, Gillman M

Epigenetics.. 2012 March 7 (3):253-60. Epub 1900 01 01.

Gene promoter methylation is associated with lung function in the elderly: the Normative Aging Study.

Lepeule J, Baccarelli A, Motta V, Cantone L, Litonjua AA, Sparrow D, Vokonas PS, Schwartz J

Epigenetics.. 2012 March 7 (3):261-9. Epub 1900 01 01.

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.

Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, Hokanson JE, Murray T, Hetmanski JB, Pillai SG, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Silverman EK, , ,

Human molecular genetics.. 2012 February 1521 (4):947-57. Epub 11/11/2011.

Genetic and histologic evidence for autophagy in asthma pathogenesis.

Poon AH, Chouiali F, Tse SM, Litonjua AA, Hussain SN, Baglole CJ, Eidelman DH, Olivenstein R, Martin JG, Weiss ST, Hamid Q, Laprise C

The Journal of allergy and clinical immunology.. 2012 February 129 (2):569-71. Epub 10/29/2011.

Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations.

Du R, Litonjua AA, Tantisira KG, Lasky-Su J, Sunyaev SR, Klanderman BJ, Celedón JC, Avila L, Soto-Quiros ME, Weiss ST

The Journal of allergy and clinical immunology.. 2012 February 129 (2):368-73, 373.e1-5. Epub 11/01/2011.

Associations of toenail arsenic, cadmium, mercury, manganese, and lead with blood pressure in the normative aging study.

Mordukhovich I, Wright RO, Hu H, Amarasiriwardena C, Baccarelli A, Litonjua A, Sparrow D, Vokonas P, Schwartz J

Environmental health perspectives.. 2012 January 120 (1):98-104. Epub 08/30/2011.

Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality.

Braun AB, Gibbons FK, Litonjua AA, Giovannucci E, Christopher KB

Critical care medicine.. 2012 January 40 (1):63-72. Epub 1900 01 01.

Alu and LINE-1 methylation and lung function in the normative ageing study.

Lange NE, Sordillo J, Tarantini L, Bollati V, Sparrow D, Vokonas P, Zanobetti A, Schwartz J, Baccarelli A, Litonjua AA, Demeo DL

BMJ open.. 2012 2 (5)Epub 10/17/2012.

Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1.

Sordillo JE, Sharma S, Poon A, Lasky-Su J, Belanger K, Milton DK, Bracken MB, Triche EW, Leaderer BP, Gold DR, Litonjua AA

BMC medical genetics.. 2011 December 812 :158. Epub 12/08/2011.

The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility.

Castaldi PJ, Cho MH, Litonjua AA, Bakke P, Gulsvik A, Lomas DA, Anderson W, Beaty TH, Hokanson JE, Crapo JD, Laird N, Silverman EK,

American journal of respiratory cell and molecular biology.. 2011 December 45 (6):1147-53. Epub 06/09/2011.

Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.

Brehm JM, Hagiwara K, Tesfaigzi Y, Bruse S, Mariani TJ, Bhattacharya S, Boutaoui N, Ziniti JP, Soto-Quiros ME, Avila L, Cho MH, Himes B, Litonjua AA, Jacobson F, Bakke P, Gulsvik A, Anderson WH, Lomas DA, Forno E, Datta S, Silverman EK, Celedón JC

Thorax.. 2011 December 66 (12):1085-90. Epub 09/15/2011.

Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study.

Wernimont SM, Clark AG, Stover PJ, Wells MT, Litonjua AA, Weiss ST, Gaziano JM, Tucker KL, Baccarelli A, Schwartz J, Bollati V, Cassano PA

BMC medical genetics.. 2011 November 2112 :150. Epub 11/21/2011.

Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.

Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST

The New England journal of medicine.. 2011 September 29365 (13):1173-83. Epub 09/26/2011.

Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Miyagawa T, Adachi M, Tanaka H, Niimi A, Matsumoto H, Ito I, Masuko H, Sakamoto T, Hizawa N, Taniguchi M, Lima JJ, Irvin CG, Peters SP, Himes BE, Litonjua AA, Tantisira KG, Weiss ST, Kamatani N, Nakamura Y, Tamari M

Nature genetics.. 2011 July 3143 (9):893-6. Epub 07/31/2011.

Forced expiratory volume in 1 second and cognitive aging in men.

Weuve J, Glymour MM, Hu H, Sparrow D, Spiro A, Vokonas PS, Litonjua AA

Journal of the American Geriatrics Society.. 2011 July 59 (7):1283-92. Epub 06/30/2011.

Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers.

Xu M, Tantisira KG, Wu A, Litonjua AA, Chu JH, Himes BE, Damask A, Weiss ST

BMC medical genetics.. 2011 June 3012 :90. Epub 06/30/2011.

SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development.

Hersh CP, Silverman EK, Gascon J, Bhattacharya S, Klanderman BJ, Litonjua AA, Lefebvre V, Sparrow D, Reilly JJ, Anderson WH, Lomas DA, Mariani TJ,

American journal of respiratory and critical care medicine.. 2011 June 1183 (11):1482-9. Epub 02/17/2011.

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report.

Silverman EK, Vestbo J, Agusti A, Anderson W, Bakke PS, Barnes KC, Barr RG, Bleecker ER, Boezen HM, Burkart KM, Celli BR, Cho MH, Cookson WO, Croxton T, Daley D, DeMeo DL, Gan W, Garcia-Aymerich J, Hall IP, Hansel NN, Hersh CP, Kalsheker N, Kiley JP, Kim WJ, Lambrechts D, Lee SD, Litonjua AA, Lomas DA, London SJ, Nishimura M, Nørdestgaard BG, O'Donnell CJ, Postma DS, Puhan MA, Tesfaigzi Y, Tobin MD, Vogelmeier C, Wilk JB, Wouters E, Young RP, Ziegler-Heitbrock L, MacNee W, Crapo JD

COPD.. 2011 April 8 (2):121-35. Epub 1900 01 01.

Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease.

Foreman MG, Kong X, DeMeo DL, Pillai SG, Hersh CP, Bakke P, Gulsvik A, Lomas DA, Litonjua AA, Shapiro SD, Tal-Singer R, Silverman EK

American journal of respiratory cell and molecular biology.. 2011 March 44 (3):316-22. Epub 05/06/2010.

Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study.

Zhu ZZ, Sparrow D, Hou L, Tarantini L, Bollati V, Litonjua AA, Zanobetti A, Vokonas P, Wright RO, Baccarelli A, Schwartz J

Cancer causes & control : CCC.. 2011 March 22 (3):437-47. Epub 12/25/2010.

Regulatory haplotypes in ARG1 are associated with altered bronchodilator response.

Duan QL, Gaume BR, Hawkins GA, Himes BE, Bleecker ER, Klanderman B, Irvin CG, Peters SP, Meyers DA, Hanrahan JP, Lima JJ, Litonjua AA, Tantisira KG, Liggett SB

American journal of respiratory and critical care medicine.. 2011 February 15183 (4):449-54. Epub 09/17/2010.

Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes.

Lange NE, Zhou X, Lasky-Su J, Himes BE, Lazarus R, Soto-Quirós M, Avila L, Celedón JC, Hawrylowicz CM, Raby BA, Litonjua AA

BMC medical genetics.. 2011 February 1512 :26. Epub 02/15/2011.

Vitamin D deficiency is associated with decreased lung function in Chinese adults with asthma.

Li F, Peng M, Jiang L, Sun Q, Zhang K, Lian F, Litonjua AA, Gao J, Gao X

Respiration; international review of thoracic diseases.. 2011 81 (6):469-75. Epub 12/01/2010.

Genetics of sputum gene expression in chronic obstructive pulmonary disease.

Qiu W, Cho MH, Riley JH, Anderson WH, Singh D, Bakke P, Gulsvik A, Litonjua AA, Lomas DA, Crapo JD, Beaty TH, Celli BR, Rennard S, Tal-Singer R, Fox SM, Silverman EK, Hersh CP,

PloS one.. 2011 6 (9):e24395. Epub 09/16/2011.

Ischemic heart disease and stroke in relation to blood DNA methylation.

Baccarelli A, Wright R, Bollati V, Litonjua A, Zanobetti A, Tarantini L, Sparrow D, Vokonas P, Schwartz J

Epidemiology.. 2010 November 21 (6):819-28. Epub 1900 01 01.

Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations.

Wu AC, Lasky-Su J, Rogers CA, Klanderman BJ, Litonjua AA

American journal of respiratory and critical care medicine.. 2010 October 1182 (7):884-9. Epub 06/10/2010.

Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.

Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EF, Scholand MB, Coon H, Hoidal J, Silverman EK

American journal of respiratory and critical care medicine.. 2010 September 1182 (5):605-13. Epub 05/12/2010.

Maternal dietary pattern during pregnancy is not associated with recurrent wheeze in children.

Lange NE, Rifas-Shiman SL, Camargo CA, Gold DR, Gillman MW, Litonjua AA

The Journal of allergy and clinical immunology.. 2010 August 126 (2):250-5, 255.e1-4. Epub 06/26/2010.

Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD.

Sørheim IC, DeMeo DL, Washko G, Litonjua A, Sparrow D, Bowler R, Bakke P, Pillai SG, Coxson HO, Lomas DA, Silverman EK, Hersh CP,

COPD.. 2010 August 7 (4):262-8. Epub 1900 01 01.

Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study.

Brehm JM, Schuemann B, Fuhlbrigge AL, Hollis BW, Strunk RC, Zeiger RS, Weiss ST, Litonjua AA,

The Journal of allergy and clinical immunology.. 2010 July 126 (1):52-8.e5. Epub 06/09/2010.

Multiple microbial exposures in the home may protect against asthma or allergy in childhood.

Sordillo JE, Hoffman EB, Celedón JC, Litonjua AA, Milton DK, Gold DR

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.. 2010 June 40 (6):902-10. Epub 04/13/2010.

Repetitive element DNA methylation and circulating endothelial and inflammation markers in the VA normative aging study.

Baccarelli A, Tarantini L, Wright RO, Bollati V, Litonjua AA, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J

Epigenetics.. 2010 April 5 (3):222-8. Epub 04/01/2010.

Variants in FAM13A are associated with chronic obstructive pulmonary disease.

Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK

Nature genetics.. 2010 March 42 (3):200-2. Epub 02/21/2010.

Polymorphisms of chitinases are not associated with asthma.

Wu AC, Lasky-Su J, Rogers CA, Klanderman BJ, Litonjua A

The Journal of allergy and clinical immunology.. 2010 March 125 (3):754-7, 757.e1-757.e2. Epub 1900 01 01.

Development of a Pharmacogenetic Predictive Test in asthma: proof of concept.

Wu AC, Himes BE, Lasky-Su J, Litonjua A, Li L, Lange C, Lima J, Irvin CG, Weiss ST

Pharmacogenetics and genomics.. 2010 February 20 (2):86-93. Epub 1900 01 01.

MMP12, lung function, and COPD in high-risk populations.

Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, Kull I, Kere J, Svartengren M, Pershagen G, Wickman M, Lange C, Demeo DL, Hersh CP, Klanderman BJ, Raby BA, Sparrow D, Shapiro SD, Silverman EK, Litonjua AA, Weiss ST, Celedón JC

The New England journal of medicine.. 2009 December 31361 (27):2599-608. Epub 12/16/2009.

Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men.

Wilker EH, Alexeeff SE, Poon A, Litonjua AA, Sparrow D, Vokonas PS, Mittleman MA, Schwartz J

Atherosclerosis.. 2009 October 206 (2):480-5. Epub 03/19/2009.

Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.

DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK

American journal of human genetics.. 2009 October 85 (4):493-502. Epub 1900 01 01.

Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema.

Hersh CP, Hansel NN, Barnes KC, Lomas DA, Pillai SG, Coxson HO, Mathias RA, Rafaels NM, Wise RA, Connett JE, Klanderman BJ, Jacobson FL, Gill R, Litonjua AA, Sparrow D, Reilly JJ, Silverman EK,

American journal of respiratory cell and molecular biology.. 2009 September 41 (3):324-31. Epub 01/08/2009.

1alpha,25(OH)2D3 and its 3-epimer promote rat lung alveolar epithelial-mesenchymal interactions and inhibit lipofibroblast apoptosis.

Sakurai R, Shin E, Fonseca S, Sakurai T, Litonjua AA, Weiss ST, Torday JS, Rehan VK

American journal of physiology. Lung cellular and molecular physiology.. 2009 September 297 (3):L496-505. Epub 07/02/2009.

Predicting response to short-acting bronchodilator medication using Bayesian networks.

Himes BE, Wu AC, Duan QL, Klanderman B, Litonjua AA, Tantisira K, Ramoni MF, Weiss ST

Pharmacogenomics.. 2009 September 10 (9):1393-412. Epub 1900 01 01.

Associations of IL6 polymorphisms with lung function decline and COPD.

He JQ, Foreman MG, Shumansky K, Zhang X, Akhabir L, Sin DD, Man SF, DeMeo DL, Litonjua AA, Silverman EK, Connett JE, Anthonisen NR, Wise RA, Paré PD, Sandford AJ

Thorax.. 2009 August 64 (8):698-704. Epub 04/08/2009.

Predictors of poor response during asthma therapy differ with definition of outcome.

Rogers AJ, Tantisira KG, Fuhlbrigge AL, Litonjua AA, Lasky-Su JA, Szefler SJ, Strunk RC, Zeiger RS, Weiss ST

Pharmacogenomics.. 2009 August 10 (8):1231-42. Epub 1900 01 01.

Analysis of exonic elastin variants in severe, early-onset chronic obstructive pulmonary disease.

Cho MH, Ciulla DM, Klanderman BJ, Hersh CP, Litonjua AA, Sparrow D, Raby BA, Silverman EK

American journal of respiratory cell and molecular biology.. 2009 June 40 (6):751-5. Epub 11/21/2008.

Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter.

Wilker E, Mittleman MA, Litonjua AA, Poon A, Baccarelli A, Suh H, Wright RO, Sparrow D, Vokonas P, Schwartz J

Environmental health perspectives.. 2009 June 117 (6):935-40. Epub 02/03/2009.

Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica.

Brehm JM, Celedón JC, Soto-Quiros ME, Avila L, Hunninghake GM, Forno E, Laskey D, Sylvia JS, Hollis BW, Weiss ST, Litonjua AA

American journal of respiratory and critical care medicine.. 2009 May 1179 (9):765-71. Epub 01/29/2009.

Rapid DNA methylation changes after exposure to traffic particles.

Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J

American journal of respiratory and critical care medicine.. 2009 April 1179 (7):572-8. Epub 01/08/2009.

Decline in genomic DNA methylation through aging in a cohort of elderly subjects.

Bollati V, Schwartz J, Wright R, Litonjua A, Tarantini L, Suh H, Sparrow D, Vokonas P, Baccarelli A

Mechanisms of ageing and development.. 2009 April 130 (4):234-9. Epub 12/27/2008.

INSIG2 is Associated with Lower Gain in Weight-for-Length Between Birth and Age 6 Months.

Wu AC, Gillman MW, Taveras EM, Litonjua AA

Clinical medicine. Pediatrics. 2009 3 :33-37. Epub 1900 01 01.

Folliculin mutations are not associated with severe COPD.

Cho MH, Klanderman BJ, Litonjua AA, Sparrow D, Silverman EK, Raby BA

BMC medical genetics.. 2008 December 309 :120. Epub 12/30/2008.

Ozone exposure, antioxidant genes, and lung function in an elderly cohort: VA normative aging study.

Alexeeff SE, Litonjua AA, Wright RO, Baccarelli A, Suh H, Sparrow D, Vokonas PS, Schwartz J

Occupational and environmental medicine.. 2008 November 65 (11):736-42. Epub 06/04/2008.

Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program.

Sharma S, Litonjua AA, Tantisira KG, Fuhlbrigge AL, Szefler SJ, Strunk RC, Zeiger RS, Murphy AJ, Weiss ST,

The Journal of allergy and clinical immunology.. 2008 November 122 (5):921-928.e4. Epub 10/10/2008.

ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.

Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST

American journal of respiratory and critical care medicine.. 2008 October 1178 (7):688-94. Epub 07/10/2008.

Particulate air pollution as a risk factor for ST-segment depression in patients with coronary artery disease.

Chuang KJ, Coull BA, Zanobetti A, Suh H, Schwartz J, Stone PH, Litonjua A, Speizer FE, Gold DR

Circulation.. 2008 September 23118 (13):1314-20. Epub 09/08/2008.

Diversity of the gut microbiota and eczema in early life.

Forno E, Onderdonk AB, McCracken J, Litonjua AA, Laskey D, Delaney ML, Dubois AM, Gold DR, Ryan LM, Weiss ST, Celedón JC

Clinical and molecular allergy : CMA.. 2008 September 226 :11. Epub 09/22/2008.

Association between 24-hour urinary cadmium and pulmonary function among community-exposed men: the VA Normative Aging Study.

Lampe BJ, Park SK, Robins T, Mukherjee B, Litonjua AA, Amarasiriwardena C, Weisskopf M, Sparrow D, Hu H

Environmental health perspectives.. 2008 September 116 (9):1226-30. Epub 1900 01 01.

Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma.

Tantisira KG, Lazarus R, Litonjua AA, Klanderman B, Weiss ST

Pharmacogenetics and genomics.. 2008 August 18 (8):733-7. Epub 1900 01 01.

Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma.

Poon AH, Tantisira KG, Litonjua AA, Lazarus R, Xu J, Lasky-Su J, Lima JJ, Irvin CG, Hanrahan JP, Lange C, Weiss ST

Pharmacogenetics and genomics.. 2008 May 18 (5):373-82. Epub 1900 01 01.

Higher adiposity in infancy associated with recurrent wheeze in a prospective cohort of children.

Taveras EM, Rifas-Shiman SL, Camargo CA, Gold DR, Litonjua AA, Oken E, Weiss ST, Gillman MW

The Journal of allergy and clinical immunology.. 2008 May 121 (5):1161-1166.e3. Epub 1900 01 01.

Cardiac autonomic dysfunction: effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms.

Baccarelli A, Cassano PA, Litonjua A, Park SK, Suh H, Sparrow D, Vokonas P, Schwartz J

Circulation.. 2008 April 8117 (14):1802-9. Epub 03/31/2008.

Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study.

Alexeeff SE, Litonjua AA, Suh H, Sparrow D, Vokonas PS, Schwartz J

Chest.. 2007 December 132 (6):1890-7. Epub 10/09/2007.

FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma.

Tantisira KG, Silverman ES, Mariani TJ, Xu J, Richter BG, Klanderman BJ, Litonjua AA, Lazarus R, Rosenwasser LJ, Fuhlbrigge AL, Weiss ST

The Journal of allergy and clinical immunology.. 2007 December 120 (6):1285-91. Epub 11/05/2007.

Cumulative community-level lead exposure and pulse pressure: the normative aging study.

Perlstein T, Weuve J, Schwartz J, Sparrow D, Wright R, Litonjua A, Nie H, Hu H

Environmental health perspectives.. 2007 December 115 (12):1696-700. Epub 1900 01 01.

Prevalence and titer of IgE antibodies to mouse allergens.

Platts-Mills TA, Satinover SM, Naccara L, Litonjua AA, Phipatanakul W, Carter MC, Heymann PW, Woodfolk JA, Peters EJ, Gold DR

The Journal of allergy and clinical immunology.. 2007 November 120 (5):1058-64. Epub 09/04/2007.

Particulate air pollution, oxidative stress genes, and heart rate variability in an elderly cohort.

Chahine T, Baccarelli A, Litonjua A, Wright RO, Suh H, Gold DR, Sparrow D, Vokonas P, Schwartz J

Environmental health perspectives.. 2007 November 115 (11):1617-22. Epub 1900 01 01.

Statin use reduces decline in lung function: VA Normative Aging Study.

Alexeeff SE, Litonjua AA, Sparrow D, Vokonas PS, Schwartz J

American journal of respiratory and critical care medicine.. 2007 October 15176 (8):742-7. Epub 08/02/2007.

Sensitization to mouse allergen and asthma and asthma morbidity among women in Boston.

Phipatanakul W, Litonjua AA, Platts-Mills TA, Naccara LM, Celedón JC, Abdulkerim H, Hoffman EB, Gold DR

The Journal of allergy and clinical immunology.. 2007 October 120 (4):954-6. Epub 06/25/2007.

Genetic determinants of emphysema distribution in the national emphysema treatment trial.

DeMeo DL, Hersh CP, Hoffman EA, Litonjua AA, Lazarus R, Sparrow D, Benditt JO, Criner G, Make B, Martinez FJ, Scanlon PD, Sciurba FC, Utz JP, Reilly JJ, Silverman EK

American journal of respiratory and critical care medicine.. 2007 July 1176 (1):42-8. Epub 03/15/2007.

Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood.

Celedón JC, Milton DK, Ramsey CD, Litonjua AA, Ryan L, Platts-Mills TA, Gold DR

The Journal of allergy and clinical immunology.. 2007 July 120 (1):144-9. Epub 05/15/2007.

Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age.

Camargo CA, Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, Kleinman K, Gillman MW

The American journal of clinical nutrition.. 2007 March 85 (3):788-95. Epub 1900 01 01.

Maternal vitamin D intake during pregnancy and early childhood wheezing.

Devereux G, Litonjua AA, Turner SW, Craig LC, McNeill G, Martindale S, Helms PJ, Seaton A, Weiss ST

The American journal of clinical nutrition.. 2007 March 85 (3):853-9. Epub 1900 01 01.

Cord blood cytokines and acute lower respiratory illnesses in the first year of life.

Ly NP, Rifas-Shiman SL, Litonjua AA, Tzianabos AO, Schaub B, Ruiz-Pérez B, Tantisira KG, Finn PW, Gillman MW, Weiss ST, Gold DR

Pediatrics.. 2007 January 119 (1):e171-8. Epub 12/04/2006.

Predictors of cord blood IgE levels in children at risk for asthma and atopy.

Scirica CV, Gold DR, Ryan L, Abulkerim H, Celedón JC, Platts-Mills TA, Naccara LM, Weiss ST, Litonjua AA

The Journal of allergy and clinical immunology.. 2007 January 119 (1):81-8. Epub 10/18/2006.

Respiratory illnesses in early life and asthma and atopy in childhood.

Ramsey CD, Gold DR, Litonjua AA, Sredl DL, Ryan L, Celedón JC

The Journal of allergy and clinical immunology.. 2007 January 119 (1):150-6. Epub 10/23/2006.

Uric acid and the development of hypertension: the normative aging study.

Perlstein TS, Gumieniak O, Williams GH, Sparrow D, Vokonas PS, Gaziano M, Weiss ST, Litonjua AA

Hypertension.. 2006 December 48 (6):1031-6. Epub 10/23/2006.

Genetic linkage and association analysis of COPD-related traits on chromosome 8p.

Hersh CP, DeMeo DL, Raby BA, Litonjua AA, Sylvia JS, Sparrow D, Reilly JJ, Silverman EK

COPD.. 2006 December 3 (4):189-94. Epub 1900 01 01.

Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility.

McGraw DW, Fogel KM, Kong S, Litonjua AA, Kranias EG, Aronow BJ, Liggett SB

Physiological genomics.. 2006 October 1127 (2):171-7. Epub 07/18/2006.

Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age.

Litonjua AA, Rifas-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camargo CA, Weiss ST, Gillman MW, Gold DR

The American journal of clinical nutrition.. 2006 October 84 (4):903-11. Epub 1900 01 01.

Mode of delivery and cord blood cytokines: a birth cohort study.

Ly NP, Ruiz-Pérez B, Onderdonk AB, Tzianabos AO, Litonjua AA, Liang C, Laskey D, Delaney ML, DuBois AM, Levy H, Gold DR, Ryan LM, Weiss ST, Celedón JC

Clinical and molecular allergy : CMA.. 2006 September 264 :13. Epub 09/26/2006.

The SERPINE2 gene is associated with chronic obstructive pulmonary disease.

DeMeo D, Mariani T, Lange C, Lake S, Litonjua A, Celedón J, Reilly J, Chapman HA, Sparrow D, Spira A, Beane J, Pinto-Plata V, Speizer FE, Shapiro S, Weiss ST, Silverman EK

Proceedings of the American Thoracic Society.. 2006 August 3 (6):502. Epub 1900 01 01.

Sensitization to aeroallergens and airway hyperresponsiveness at 7 years of age.

Tepas EC, Litonjua AA, Celedón JC, Sredl D, Gold DR

Chest.. 2006 June 129 (6):1500-8. Epub 1900 01 01.

Prenatal, perinatal, and heritable influences on cord blood immune responses.

Willwerth BM, Schaub B, Tantisira KG, Gold DR, Palmer LJ, Litonjua AA, Perkins DL, Schroeter C, Gibbons FK, Gillman MW, Weiss ST, Finn PW

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.. 2006 March 96 (3):445-53. Epub 1900 01 01.

The SERPINE2 gene is associated with chronic obstructive pulmonary disease.

Demeo DL, Mariani TJ, Lange C, Srisuma S, Litonjua AA, Celedon JC, Lake SL, Reilly JJ, Chapman HA, Mecham BH, Haley KJ, Sylvia JS, Sparrow D, Spira AE, Beane J, Pinto-Plata V, Speizer FE, Shapiro SD, Weiss ST, Silverman EK

American journal of human genetics.. 2006 February 78 (2):253-64. Epub 12/15/2005.

T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.

Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST

American journal of respiratory and critical care medicine.. 2006 January 1173 (1):64-70. Epub 09/22/2005.

Lung function in type 2 diabetes: the Normative Aging Study.

Litonjua AA, Lazarus R, Sparrow D, Demolles D, Weiss ST

Respiratory medicine.. 2005 December 99 (12):1583-90. Epub 04/26/2005.

A case-cohort design for assessing covariate effects in longitudinal studies.

Pfeiffer RM, Ryan L, Litonjua A, Pee D

Biometrics.. 2005 December 61 (4):982-91. Epub 1900 01 01.

A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease.

Kelleher CM, Silverman EK, Broekelmann T, Litonjua AA, Hernandez M, Sylvia JS, Stoler J, Reilly JJ, Chapman HA, Speizer FE, Weiss ST, Mecham RP, Raby BA

American journal of respiratory cell and molecular biology.. 2005 October 33 (4):355-62. Epub 08/04/2005.

Paternal history of asthma and airway responsiveness in children with asthma.

Raby BA, Van Steen K, Celedón JC, Litonjua AA, Lange C, Weiss ST,

American journal of respiratory and critical care medicine.. 2005 September 1172 (5):552-8. Epub 06/03/2005.

Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.

Lim U, Peng K, Shane B, Stover PJ, Litonjua AA, Weiss ST, Gaziano JM, Strawderman RL, Raiszadeh F, Selhub J, Tucker KL, Cassano PA

The Journal of nutrition.. 2005 August 135 (8):1989-94. Epub 1900 01 01.

Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.

Hersh CP, Demeo DL, Lange C, Litonjua AA, Reilly JJ, Kwiatkowski D, Laird N, Sylvia JS, Sparrow D, Speizer FE, Weiss ST, Silverman EK

American journal of respiratory cell and molecular biology.. 2005 July 33 (1):71-8. Epub 04/07/2005.

Air pollution and ST-segment depression in elderly subjects.

Gold DR, Litonjua AA, Zanobetti A, Coull BA, Schwartz J, MacCallum G, Verrier RL, Nearing BD, Canner MJ, Suh H, Stone PH

Environmental health perspectives.. 2005 July 113 (7):883-7. Epub 1900 01 01.

Fetal cord blood: aspects of heightened immune responses.

Schaub B, Tantisira KG, Gibbons FK, He H, Litonjua AA, Gillman MW, Weiss S, Perkins DL, Gold DR, Finn PW

Journal of clinical immunology.. 2005 July 25 (4):329-37. Epub 1900 01 01.

Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways.

Tantisira KG, Small KM, Litonjua AA, Weiss ST, Liggett SB

Human molecular genetics.. 2005 June 1514 (12):1671-7. Epub 05/06/2005.

Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma.

Litonjua AA, Tantisira KG, Lake S, Lazarus R, Richter BG, Gabriel S, Silverman ES, Weiss ST

Respiratory research.. 2005 June 36 (1):52. Epub 06/03/2005.

Traffic related pollution and heart rate variability in a panel of elderly subjects.

Schwartz J, Litonjua A, Suh H, Verrier M, Zanobetti A, Syring M, Nearing B, Verrier R, Stone P, MacCallum G, Speizer FE, Gold DR

Thorax.. 2005 June 60 (6):455-61. Epub 1900 01 01.

Polymorphisms in the 5' region of the CD14 gene are associated with eczema in young children.

Litonjua AA, Belanger K, Celedón JC, Milton DK, Bracken MB, Kraft P, Triche EW, Sredl DL, Weiss ST, Leaderer BP, Gold DR

The Journal of allergy and clinical immunology.. 2005 May 115 (5):1056-62. Epub 1900 01 01.

Variation in total and specific IgE: effects of ethnicity and socioeconomic status.

Litonjua AA, Celedón JC, Hausmann J, Nikolov M, Sredl D, Ryan L, Platts-Mills TA, Weiss ST, Gold DR

The Journal of allergy and clinical immunology.. 2005 April 115 (4):751-7. Epub 1900 01 01.

Low-normal gestational age as a predictor of asthma at 6 years of age.

Raby BA, Celedón JC, Litonjua AA, Phipatanakul W, Sredl D, Oken E, Ryan L, Weiss ST, Gold DR

Pediatrics.. 2004 September 114 (3):e327-32. Epub 1900 01 01.

Ambient air pollution and oxygen saturation.

DeMeo DL, Zanobetti A, Litonjua AA, Coull BA, Schwartz J, Gold DR

American journal of respiratory and critical care medicine.. 2004 August 15170 (4):383-7. Epub 05/13/2004.

The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).

Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK

Human molecular genetics.. 2004 August 113 (15):1649-56. Epub 06/02/2004.

Endotoxin exposure and eczema in the first year of life.

Phipatanakul W, Celedón JC, Raby BA, Litonjua AA, Milton DK, Sredl D, Weiss ST, Gold DR

Pediatrics.. 2004 July 114 (1):13-8. Epub 1900 01 01.

Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men.

Litonjua AA, Silverman EK, Tantisira KG, Sparrow D, Sylvia JS, Weiss ST

Chest.. 2004 July 126 (1):66-74. Epub 1900 01 01.

Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP).

Tantisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL,

Thorax.. 2003 December 58 (12):1036-41. Epub 1900 01 01.

Day care attendance in early life, maternal history of asthma, and asthma at the age of 6 years.

Celedon JC, Wright RJ, Litonjua AA, Sredl D, Ryan L, Weiss ST, Gold DR

American journal of respiratory and critical care medicine.. 2003 May 1167 (9):1239-43. Epub 11/21/2002.

Serum interferon-gamma is associated with longitudinal decline in lung function among asthmatic patients: the Normative Aging Study.

Litonjua AA, Sparrow D, Guevarra L, O'Connor GT, Weiss ST, Tollerud DJ

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.. 2003 April 90 (4):422-8. Epub 1900 01 01.

Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women.

Tsunoda M, Litonjua AA, Kuniak MP, Weiss ST, Satoh T, Guevarra L, Tollerud DJ

International archives of allergy and immunology.. 2003 February 130 (2):158-64. Epub 1900 01 01.

Bottle feeding in the bed or crib before sleep time and wheezing in early childhood.

Celedón JC, Litonjua AA, Ryan L, Weiss ST, Gold DR

Pediatrics.. 2002 December 110 (6):e77. Epub 1900 01 01.

A longitudinal analysis of wheezing in young children: the independent effects of early life exposure to house dust endotoxin, allergens, and pets.

Litonjua AA, Milton DK, Celedon JC, Ryan L, Weiss ST, Gold DR

The Journal of allergy and clinical immunology.. 2002 November 110 (5):736-42. Epub 1900 01 01.

Exposure to cat allergen, maternal history of asthma, and wheezing in first 5 years of life.

Celedón JC, Litonjua AA, Ryan L, Platts-Mills T, Weiss ST, Gold DR

Lancet.. 2002 September 7360 (9335):781-2. Epub 1900 01 01.

Lack of association between antibiotic use in the first year of life and asthma, allergic rhinitis, or eczema at age 5 years.

Celedón JC, Litonjua AA, Ryan L, Weiss ST, Gold DR

American journal of respiratory and critical care medicine.. 2002 July 1166 (1):72-5. Epub 1900 01 01.

Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the Normative Aging Study.

Litonjua AA, Sparrow D, Celedon JC, DeMolles D, Weiss ST

Thorax.. 2002 July 57 (7):581-5. Epub 1900 01 01.

Day care attendance, respiratory tract illnesses, wheezing, asthma, and total serum IgE level in early childhood.

Celedón JC, Litonjua AA, Ryan L, Weiss ST, Gold DR

Archives of pediatrics & adolescent medicine.. 2002 March 156 (3):241-5. Epub 1900 01 01.

Body mass index and asthma in adults in families of subjects with asthma in Anqing, China.

Celedón JC, Palmer LJ, Litonjua AA, Weiss ST, Wang B, Fang Z, Xu X

American journal of respiratory and critical care medicine.. 2001 November 15164 (10 Pt 1):1835-40. Epub 1900 01 01.

Exposure to cockroach allergen in the home is associated with incident doctor-diagnosed asthma and recurrent wheezing.

Litonjua AA, Carey VJ, Burge HA, Weiss ST, Gold DR

The Journal of allergy and clinical immunology.. 2001 January 107 (1):41-7. Epub 1900 01 01.

Ambient pollution and heart rate variability.

Gold DR, Litonjua A, Schwartz J, Lovett E, Larson A, Nearing B, Allen G, Verrier M, Cherry R, Verrier R

Circulation.. 2000 March 21101 (11):1267-73. Epub 1900 01 01.

Race, socioeconomic factors, and area of residence are associated with asthma prevalence.

Litonjua AA, Carey VJ, Weiss ST, Gold DR

Pediatric pulmonology.. 1999 December 28 (6):394-401. Epub 1900 01 01.

Day care attendance in the first year of life and illnesses of the upper and lower respiratory tract in children with a familial history of atopy.

Celedon JC, Litonjua AA, Weiss ST, Gold DR

Pediatrics.. 1999 September 104 (3 Pt 1):495-500. Epub 1900 01 01.

The FEF25-75/FVC ratio is associated with methacholine airway responsiveness. The normative aging study.

Litonjua AA, Sparrow D, Weiss ST

American journal of respiratory and critical care medicine.. 1999 May 159 (5 Pt 1):1574-9. Epub 1900 01 01.

Parental history and the risk for childhood asthma. Does mother confer more risk than father?

Litonjua AA, Carey VJ, Burge HA, Weiss ST, Gold DR

American journal of respiratory and critical care medicine.. 1998 July 158 (1):176-81. Epub 1900 01 01.

Sensitization to cat allergen is associated with asthma in older men and predicts new-onset airway hyperresponsiveness. The Normative Aging Study.

Litonjua AA, Sparrow D, Weiss ST, O'Connor GT, Long AA, Ohman JL

American journal of respiratory and critical care medicine.. 1997 July 156 (1):23-7. Epub 1900 01 01.

Books

Fishman's Pulmonary Diseases and Disorders (2015)

Chapter: Asthma: Epidemiology

Authors: Litonjua AA, Apter A, Weiss ST

Publisher: McGraw-Hill, New York 2015

Vitamin D and the Lung: Mechanisms and Disease Associations. Humana Press: New York, 2012. (2012)

Authors: Litonjua AA (Editor)

Publisher: Humana Press, New York 2012

Vitamin D and the Lung: Mechanisms and Disease Associations (2012)

Chapter: The role of vitamin D in the development, exacerbation, and severity of asthma and allergic diseases

Authors: Litonjua AA

Publisher: Humana Press, New York 2012

Encyclopedia of Respiratory Medicine (2006)

Chapter: Genetics and Pulmonary Disease: Gene Association Studies

Authors: Litonjua AA, Celedon JC

Publisher: Academic Press, Oxford 2006

Respiratory Genetics (2005)

Chapter: Phenotypes for human respiratory genetics

Authors: Litonjua AA, Weiss ST

Publisher: Oxford University Press, New York 2005

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