Recent Publications
Rambout X, Cho H, Blanc R, Lyu Q, Miano JM, Chakkalakal JV, Nelson GM, Yalamanchili HK, Adelman K, Maquat LE. PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII. Mol Cell. 2023 Jan 19;83(2):186-202.e11. doi: 10.1016/j.molcel.2022.12.022. PMID: 36669479; PMCID: PMC9951270.
Lu JY, Simon M, Zhao Y, Ablaeva J, Corson N, Choi Y, Yamada KYH, Schork NJ, Hood WR, Hill GE, Miller RA, Seluanov A, Gorbunova V. Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation. Cell Metab. 2022 Jun 7;34(6):836-856.e5. doi: 10.1016/j.cmet.2022.04.011. Epub 2022 May 16. PMID: 35580607; PMCID: PMC9364679.
Emmrich S, Trapp A, Tolibzoda Zakusilo F, Straight ME, Ying AK, Tyshkovskiy A, Mariotti M, Gray S, Zhang Z, Drage MG, Takasugi M, Klusmann JH, Gladyshev VN, Seluanov A, Gorbunova V. Characterization of naked mole-rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits. EMBO J. 2022 Aug 1;41(15):e109694. doi: 10.15252/embj.2021109694. Epub 2022 Jun 13. PMID: 35694726; PMCID: PMC9340489.
GRC Seminars & Workshops
'Omics & Donuts
June 4 / 9:30-11:30 / 3-7619
Presented by: The Center for Advanced Research Technologies (CART) and the Genomics Research Center
Join us for an informational event as we discuss advancements in genomics technologies and hear from University of Rochester researchers leveraging genomics data in their work over coffee and donuts. Learn from researchers in the Gill Lab, the Gerber Lab, and the Gorbunova Lab, and from GRC scientists.
Computational Genomics Workshop
January 10-12
Presented by: The Genomics Research Center and the Georgen Institute for Data Science
10X Genomics: Sample Preparation for Single Cell Analysis: Basics and Beyond
October 14th, 4-5 pm Medical Center K-207
Presented By: Patrick Murphy, PhD
The vast complexities of biology require approaches that build a complete picture from single
cells to tissues and beyond. Single cell analysis is a powerful technique to characterize
complex tissue types, identify rare cell populations, uncover regulatory relationships between
genes, and track cell trajectories. From sample handling to cell dissociation, there are a
number of technical considerations that influence cell viability and data quality of single cell
genomics, single cell epigenomics, and single cell gene expression experiments. Join us for
this seminar, which covers critical sample prep decisions and technical considerations for
single cell assay design and optimization.
Snacks will be provided.