URMC / Research / Rochester Genomics Center / High-Throughput Content Screening
High-Throughput Content Screening
University of Rochester uses high-throughput screening to investigate salinomycin impact on myofribroblast activation
![Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin paper published by the University of Rochester](/MediaLibraries/URMCMedia/research/for-researchers/shared-resource-labs-facilities/rochester-genomics-center/images/HTScreening_Publication.JPG)
Click here for access to the publication.
Available Libraries:
The Spectrum Collection:
This collection contains 2560 compounds including all compounds in the US and International Drug collections along with Natural Product and Discover libraries from MicroSource Discovery Systems.
ChemBridge DIVERset:
Custom set of ~20,000 DIVERset compounds from ChemBridge.
Human Druggable Genome-wide RNAi:
Collections of Ambion Silencer Select siRNAs that target 9031 genes from Thermo Fisher Scientific.
Murine Genome-Wide Lentiviral shRNA:
Simple hairpin shRNA libraries developed by the RNAi consortium (TRC).
High-Throughput Screening Equipment:
![Perkin Elmer Zephyr Instrument](/MediaLibraries/URMCMedia/research/for-researchers/shared-resource-labs-facilities/rochester-genomics-center/images/Zephyr.png)
![Celigo Cytometer](/MediaLibraries/URMCMedia/research/for-researchers/shared-resource-labs-facilities/rochester-genomics-center/images/CeligoCytometer.JPG)
![MultiDrop Combi Reagent Dispenser](/MediaLibraries/URMCMedia/research/for-researchers/shared-resource-labs-facilities/rochester-genomics-center/images/HTScreeningEquip_MultiDropCombi.JPG)