Cell Cycle & Cancer
Understanding the differences in cell division and its relationship to the development of cancer.
Active Research Laboratories
- Boutz Lab - Understanding the essential roles of RNA processing in normal and tumor cell physiology, and to uncover the molecular mechanisms by which drugs alter gene expression
- Land Lab - Cooperation of Oncogenic Mutations in the Control of Malignancy
- Munger Lab - Mechanisms of Pathogenic Metabolic Manipulation
- Vertino Lab - Cancer epigenetics and novel mechanisms of gene silencing in cancer
Cell Signaling & Metabolic Regulation
Understanding complex system of communication that governs basic cellular activities and coordinates cell actions in order to effectively treat diseases.
Active Research Laboratories
- Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Land Lab - Cooperation of Oncogenic Mutations in the Control of Malignancy
- Munger Lab - Mechanisms of Pathogenic Metabolic Manipulation
Chromatin Structure, Gene Regulation & Repair
Study of defined protein-DNA interactions, protein modification and mutations that influence chromatin structure and gene regulation.
Active Research Laboratories
Genomics & Model Systems for Development
Determining DNA sequences of organisms and fine-scale genetic mapping efforts.
Active Research Laboratories
- Boutz Lab - Understanding the essential roles of RNA processing in normal and tumor cell physiology, and to uncover the molecular mechanisms by which drugs alter gene expression
- Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Grayhack Lab - The Roles of the Genetic Code in Translation
- Phizicky Lab - tRNA Biogenesis, Function & Quality Control
- Puzas Lab - Molecular and Cellular Biology of the Skeletal System
- Rustchenko-Bulgac Lab - Chromosome Instability
Membrane Biology
The study of the biological and physiochemical characteristics of membranes.
Active Research Laboratories
- Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Grossfield Lab - Computer Modeling to Understand Structure and Thermodynamics of Biological Molecules
- Mathews Lab - Computational Biology and Bioinformatics
- Waugh Lab - Cell Deformability & Cell Adhesion
Molecular Biophysics
Combines concepts in physics, chemistry, engineering, mathematics and biology.
Active Research Laboratories
- Ermolenko Lab - Structural Dynamics of Translation
- Grossfield Lab - Computer Modeling to Understand Structure and Thermodynamics of Biological Molecules
- Kielkopf Lab - Pre-mRNA Splicing for Treatment of Human Disease
- Benjamin Miller Lab - Molecular Recognition & Biosensing
- O'Connell Lab - Biochemical mechanisms of RNA-mediated gene regulation
- Vertino Lab - Cancer epigenetics and novel mechanisms of gene silencing in cancer
- Wedekind Lab - Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
Protein Structure & Function
Structure and function of proteins from primary to quaternary structures.
Active Research Laboratories
- Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Ermolenko Lab - Structural Dynamics of Translation
- Hayes Lab - Chromatin Structure
- Kielkopf Lab - Pre-mRNA Splicing for Treatment of Human Disease
- Maquat Lab - Normal & Disease-Associated RNA Decay
- Benjamin Miller Lab - Molecular Recognition & Biosensing
- O'Connell Lab - Biochemical mechanisms of RNA-mediated gene regulation
- Phizicky Lab - tRNA Biogenesis, Function & Quality Control
- Wedekind Lab - Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
- Yu Lab - Functions & Mechanisms of RNA Modifications
RNA Structure & Processing
Generation of a mature mRNA (for protein genes) or a functional tRNA or rRNA from the primary transcript.
Active Research Laboratories
- Boutz Lab - Understanding the essential roles of RNA processing in normal and tumor cell physiology, and to uncover the molecular mechanisms by which drugs alter gene expression
- Butler Lab - Regulation of Gene Expression by Targeted Degradation of RNA
- Ermolenko Lab - Structural Dynamics of Translation
- Kielkopf Lab - Pre-mRNA Splicing for Treatment of Human Disease
- Maquat Lab - Normal & Disease-Associated RNA Decay
- Mathews Lab - Computational Biology and Bioinformatics
- O'Connell Lab - Biochemical mechanisms of RNA-mediated gene regulation
- Phizicky Lab - tRNA Biogenesis, Function & Quality Control
- Vertino Lab - Cancer epigenetics and novel mechanisms of gene silencing in cancer
- Wedekind Lab - Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
- Yu Lab - Functions & Mechanisms of RNA Modifications