Faculty
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Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism.
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Role of Type 3 Interferon in the Pathophysiology of Systemic Lupus
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Understanding the interaction of HIV with glial cells; Developing an improved live attenuated influenza vaccine (LAIV); Elucidating the host cell response to infection by viral pathogens (with emphasis on SARS-CoV-2 and Adeno-associated virus, AAV)
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Translational women’s health research; To identify previously unknown mechanisms of disease for disabling vulvar conditions, namely vulvodynia and lichens
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Defining molecular pathways by which allergens and particulates activate epithelia and dendritic cells in the lung immune system
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Development of the infant microbiome and immune system, and how that relates to development of allergic diseases
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Cancer immunotherapy/Host immune response to influenza infection/ Inflammation biology of sepsis
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Delineating mechanisms by which environmental exposures during different life stages alter immune function
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Translational cancer research and immunotherapy
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Developing methods to estimate gene regulatory networks from gene perturbation experiments
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In vitro models of human lung and vascular barriers during inflammation
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Carbohydrate and protein recognition, molecular design, and biomolecular sensing
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Platelets in vascular injury and inflammation
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Human Skin Immunology
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Innate cell antiviral responses, allergic inflammation, mucosal/airway immunity, vaccine responses

Specificity and role of CD4 T cells in response to vaccination and infection
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Neonatal immunology; T cell function in preterm infants
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Immune-pathogenesis of Viral Infections
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Cellular and molecular mechanisms of heart development, disease, and regeneration; Transcriptional regulation of fibroblast plasticity and cardiac fibrosis
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Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.
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Our research program focuses on mechanisms underlying gene environment interaction in pregnancy. We are interested in elucidating how environmental factors influence epigenetic regulation of developmental-relevant genes including imprinted genes, and how exposure modulates maternal-fetal health.
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Immune responses to respiratory viruses and experimental vaccines
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