Clinical Studies in the Department
Active Clinical Trials posted to ClinicalTrials.gov
Visual Rehabilitation After Occipital Stroke (subacute stroke patients only)
ClinicalTrials.gov NCT04798924 – URMC STUDY00005966
PI name: Krystel Huxlin, PhD
Contact: Chrys Callan
Vision Loss Impact on Navigation in Virtual Reality (subacute and chronic patients)
ClinicalTrials.gov NCT06047717 – URMC STUDY00008669
PI name: Krystel Huxlin, PhD
Contact: Chrys Callan
Effect of visual retraining after stroke (subacute and chronic patients – Not Yet Recruiting)
ClinicalTrials.gov NCT06121219 - URMC STUDY00008697
PI name: Krystel Huxlin, PhD
Contact: Chrys Callan
Study of Platelet-Rich Plasma Drops to Moderate Clinically Significant Dry Eye
ClinicalTrials.gov NCT05121493
PI name: James V. Aquavella, MD with James Zavislan, PhD and Esteban Santiago, MD
Contact: James Aquavella
Gene Therapy Study for Children With CLN5 Batten Disease (Neurogene CLN5-200, Emma Ciafaloni, MD)
ClinicalTrials.gov # NCT05228145
PI name: Alex Levin, MD
Contact: Amy Vierhile
Longitudinal Prospective Natural History Study of Retinopathy in Zellweger Spectrum Disorder (McGill University- Nancy Braverman, MD)
ClinicalTrials.gov # NCT06190626
PI name: Alex Levin, MD
Contact: Emily Schwartz
Global Patient Registry of Inherited Retinal Diseases (Janssen R&D, IRD Registry, Protocol NOPRODRPG0002)
ClinicalTrials.gov # NCT05957276
PI name: Alex Levin, MD
Contact: Emily Schwartz
Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract (EyePoint Pharmaceuticals, PROTOCOL EYP-DIP-001)
ClinicalTrials.gov # NCT05191706
PI name: Alex Levin, MD
Contact: Emily Schwartz
A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP (Beacon Therapeutics VISTA STUDY AGTC-RPGR-002)
ClinicalTrials.gov # NCT04850118
PI name: Alex Levin, MD
Contact: Alicia Papalia
Active Clinical Studies (not posted to ClinicalTrials.gov)
Analysis of miRNA content in human vitreous samples
PI name: Michael Telias, PhD
Contact: Michael Telias
MyCLopia Adaptive Optics/Visual Stimulation study
PI name: Susana Marcos, PhD
Contact: Sabya Goswami
AO MyCL Adaptive Optics/Visual Stimulation study
PI name: Susana Marcos, PhD
Contact: Sabya Goswami
Accurate IOL IntraOcular Lens Study
PI name: Susana Marcos, PhD
Contact: Derick Ansah, MD (starting June 2024 Joseph Okudolo, MD)
Chroma AO/Visual Simulation study
PI name: Susana Marcos, PhD
Contact: Tianlun Zou
Genetic Studies of Human Ocular Disorders- U.S. and Canadian subjects (Medical College of Wisconsin-Elena Semina, PhD)
PI name: Alex Levin, MD
Contact: Alicia Papalia
Laser refractive surgery in CdLS
PI name: Alex Levin, MD
Contact: Alex Levin
Tubulointerstitial nephritis and uveitis syndrome (TINU), urine β2 microglobulin: anterior uveitis: a multicenter study
PI name: Alex Levin, MD
Contact: Alex Levin
Clinical markers to identify/differentiate between OCA and HPS in different ethnicities
PI name: Alex Levin, MD
Contact: Alex Levin
MAK gene therapy for retinitis pigmentosa
PI name: Alex Levin, MD
Contact: Alex Levin
CLN3 ocular gene therapy
PI name: Alex Levin, MD
Contact: Alex Levin
CLN3 U01 NINDS Clinical Readiness Trial
PI name: Erika Augustine, MD
Contact: Erika Augustine
CLN Natural History Study
PI name: Emma Ciafaloni, MD
Contact: Emma Ciafaloni,
Induced Pluripotent Stem Cell (IPSC/iPS) as a treatment for retinal diseases
PI name: Ruchira Singh, PhD
Contact: Ruchira Singh
Retinal imaging of JNCL and ABCA4opathies
PI name: Ruchira Singh, PhD
Contact: Ruchira Singh
Retrospective Studies (not posted to ClinicalTrials.gov)
Longitudinal evolution of vision following visual cortical damage
PI name: Krystel Huxlin, PhD
Ophthalmic Findings in Alstrom Syndrome
PI name: Alex Levin, MD
Use of the modified Delphi process for the analysis of congenital corneal opacities nomenclature
PI name: Alex Levin, MD
Expanding the genetic and phenotypic bases of ocular congenital cranial dysinnervation disorders
PI name: Alex Levin, MD
Autonomic Manifestations in Congenital Cranial Dysinnervation Syndromes Microphthalmia/Anophthalmia/Coloboma (MAC) registry
PI name: Alex Levin, MD
Delphi consensus for Sturge-Weber syndrome glaucoma
PI name: Alex Levin, MD
Bardet-Biedl syndrome 1 with chorioretinal coloboma
PI name: Alex Levin, MD
OCT in Abusive Head Trauma
PI name: Alex Levin, MD
Molecular genetics approach to inherited eye disease
PI name: Alex Levin, MD
International pediatric glaucoma registry
PI name: Alex Levin, MD
The Robison D. Harley, MD Childhood Glaucoma Research Network (CGRN) International Pediatric Glaucoma Registry: The First 872 cases
PI name: Alex Levin, MD
Genetic Studies of Anterior segment Disorders
PI name: Alex Levin, MD
Peripheral retinoschisis in Infants and Children
PI name: Alex Levin, MD
Management of glaucoma tube failure
PI name: Alex Levin, MD
CLN3 Clinical Guidelines Delphi
PI name: Alex Levin, MD
Eye Tracking in Ophthalmology Trainees & Attendings Interpreting Fundus Imaging
PI name: Alex Levin, MD
Attenuated HGSNAT disease
PI name: Alex Levin, MD
Optic nerve malformations in Noonan syndrome
PI name: Alex Levin, MD
Novel ocular manifestations of Pai syndrome
PI name: Alex Levin, MD
Predictive factors for surgery in pediatric glaucoma
PI name: Alex Levin, MD