URMC / Center for Health + Technology / Research Initiatives / Publications Publications Digital Measures & Biomarkers Development of Digital Measures for Nighttime Scratch and Sleep Using Wrist-Worn Wearable Devices Digital Technology in Movement Disorders: Updates, Applications, and Challenges Remote Smartphone Monitoring of Parkinson’s Disease and Individual Response to Therapy GEORGE® – A Pilot Study of a Smartphone Application for Huntington’s Disease Deep Phenotyping of Parkinson's Disease Using Smartphones and Machine Learning to Quantify Parkinson Disease Severity: The Mobile Parkinson Disease Score Decentralized Research Recruitment for Remote Decentralized Studies in Parkinson's Disease Design of a Virtual Longitudinal Observational Study in Parkinson's disease (AT-HOME PD) Feasibility, Reliability, and Value of Remote Video-Based Trial Visits in Parkinson’s Disease Video-based Parkinson’s Disease Assessments in a Nationwide Cohort of Fox Insight Participants Video Research Visits for Atypical Parkinsonian Syndromes Among Fox Trial Finder Participants The New Normal in Clinical Trials: Decentralized Studies A Virtual Cohort Study of Individuals at Genetic Risk for Parkinson's Disease: Study Protocol and Design Remote Administration of the MDS-UPDRS in the Time of COVID-19 and Beyond Technology Research & Innovation The New Platforms of Health Care Patient Views on Telemedicine for Parkinson Disease The Parkinson's Disease E-diary: Developing a Clinical and Research Tool for the Digital Age Global, Regional, and National Burden of Parkinson's Disease, 1990-2016: A Systematic Analysis for the Global Burden of Disease Study 2016 Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home Disease Progression Modeling Developing Better Digital Health Measures of Parkinson's Disease Using Free Living Data and a Crowdsourced Data Analysis Challenge A Disease Progression Model to Quantify the Nonmotor Symptoms of Parkinson's Disease in Participants With Leucine-Rich Repeat Kinase 2 Mutation Development of a Disease Progression Model for Leucine-Rich Repeat Kinase 2 in Parkinson's Disease to Inform Clinical Trial Designs Large-Scale Identification of Clinical and Genetic Predictors of Motor Progression in Patients With Newly Diagnosed Parkinson's Disease: A Longitudinal Cohort Study and Validation A Review of Disease Progression Models of Parkinson's Disease and Applications in Clinical Trials Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease Clinical Pharmacology Isradipine Plasma Pharmacokinetics and Exposure-Response in Early Parkinson's Disease Effect of Dolutegravir and Sertraline on the Blood Brain Barrier (BBB) Pharmacotherapy Use for Non-Motor Symptoms Among de novo Parkinson's Disease Parkinson's Progression Markers Initiative Participants Neuropalliative Care Prognostic Predictors Relevant to End-of-Life Palliative Care in Parkinson's Disease and Related Disorders: A Systematic Review Palliative Care and Parkinson's Disease: Time to Move Beyond Cancer Palliative Care in Movement Disorders: An Evolving Field Joy, Suffering, and the Goals of Medicine Comparison of Integrated Outpatient Palliative Care With Standard Care in Patients With Parkinson Disease and Related Disorders: A Randomized Clinical Trial Symptom Burden Among Individuals With Parkinson Disease: A National Survey Global Health Factors Associated With Lumbar Puncture Performance in Zambia A Qualitative Study of Patient, Caregiver, Doctor and Nurse Views of Factors Influencing Lumbar Puncture Uptake in Zambia Lumbar Puncture-Related Knowledge, Attitudes, and Practices Among Patients, Caregivers, Doctors, and Nurses in Zambia A Clinical Trial of Enteral Levetiracetam for Acute Seizures in Pediatric Cerebral Malaria Advancing Health Equity Through Cross-Cutting Approaches to Health-Related Stigma Nervous System Disorders Across the Life Course in Resource-Limited Settings Mortality & Recurrent Seizure Risk After New-Onset Seizure in HIV-Positive Zambian Adults Patient Reported Outcome Measures The Spinal Muscular Atrophy Health Index: A Novel Outcome for Measuring How a Patient Feels and Functions Mexiletine in Myotonic Dystrophy Type-1: A Randomized, Double-Blind, Placebo-Controlled Trial Patient-Reported Impact of Symptoms in Huntington disease: PRISM-HD Myotonic Dystrophy Patient Preferences in Patient-Reported Outcome Measures Patient Reported Impact of Symptoms in Spinal Muscular Atrophy (PRISM-SMA) The Myotonic Dystrophy Health Index: Italian Validation of a Disease-Specific Outcome Measure Myotonic Dystrophy Health Index: Correlations With Clinical Tests and Patient Function Patient-Reported Impact of Symptoms in Myotonic Dystrophy Type 2 (PRISM-2) Myotonic Dystrophy Health Index: Initial Evaluation of a Disease‐Specific Outcome Measure Patient-Reported Impact of Symptoms in Myotonic Dystrophy Type 1 (PRISM-1) Rare Diseases Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease A Novel, Hybrid, Single- and Multi-Site Clinical Trial Design for CLN3 Disease, an Ultra-Rare Lysosomal Storage Disorder Short-Term Administration of Mycophenolate Is Well-Tolerated in CLN3 Disease (Juvenile Neuronal Ceroid Lipofuscinosis) The Care Continuum: An Evolving Model for Care and Research in Rare Diseases Clinical Trials Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial Safety of Converting From Tetrabenazine to Deutetrabenazine for the Treatment of Chorea Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial A Controlled, Randomized, Delayed-Start Study of Rasagiline in Early Parkinson Disease Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease