Publications
Publications
- Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis.; Nature communications; Vol 15(1), pp. 9859. 2024 Nov 14.
- Highlights from the 2024 Rheumatoid Arthritis Research Summit.; Seminars in arthritis and rheumatism. 2024 Nov 08.
- Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue.; Nature communications; Vol 15(1), pp. 7503. 2024 Aug 29.
- Publisher Correction: Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus.; Nature. 2024 Jul 26.
- Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus.; Nature. 2024 Jul 10.
- Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium.; Nature communications; Vol 15(1), pp. 4991. 2024 Jun 11.
- The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis.; Nature communications; Vol 15(1), pp. 4650. 2024 May 31.
- Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis.; Science translational medicine; Vol 16(742), pp. eadk3506. 2024 Apr 10.
- Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.; Nature genetics. 2024 Apr 09.
- Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis.; JCI insight; Vol 9(2). 2024 Jan 23.
- Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis.; bioRxiv : the preprint server for biology. 2024 Jan 15.
- Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.; Nature genetics; Vol 55(12), pp. 2255-2268. 2023 Nov 30.
- B Cell-Directed Therapy in Autoimmunity.; Annual review of immunology. 2023 Nov 27.
- Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.; Nature; Vol 623(7987), pp. 616-624. 2023 Nov 08.
- Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.; Frontiers in immunology; Vol 14, pp. 1237498. 2023 Aug 25.
- Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.; bioRxiv : the preprint server for biology. 2023 Jul 04.
- The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis.; bioRxiv : the preprint server for biology. 2023 Apr 08.
- Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium.; bioRxiv : the preprint server for biology. 2023 Mar 21.
- Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.; medRxiv : the preprint server for health sciences. 2023 Mar 20.
- Granzyme K+ CD8 T cells form a core population in inflamed human tissue.; Science translational medicine; Vol 14(649). 2022 Jun 15.
- Prominent B cell signature differentiates discoid from subacute cutaneous lupus erythematosus.; The Journal of investigative dermatology. 2022 May 17.
- Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression.; Cell reports; Vol 39(5). 2022 May 03.
- Small molecule inhibitors of nuclear export ameliorate lupus by modulating plasma cell generation and survival.; Arthritis & rheumatology (Hoboken, N.J.). 2022 Mar 25.
- Urine Proteomics and Renal Single Cell Transcriptomics Implicate IL-16 in Lupus Nephritis.; Arthritis & rheumatology (Hoboken, N.J.). 2021 Nov 16.
- B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-λ in Systemic Lupus Erythematosus.; Journal of immunology (Baltimore, Md. : 1950). 2021 Oct 27.
- Activated peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells.; Arthritis & rheumatology (Hoboken, N.J.). 2021 Aug 04.
- IFN- γ and TNF- α drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation.; bioRxiv : the preprint server for biology. 2020 Aug 05.
- Autoreactivity in naïve human fetal B cells is associated with commensal bacteria recognition.; Science (New York, N.Y.); Vol 369(6501). 2020 Jul 17.
- Notch signalling drives synovial fibroblast identity and arthritis pathology.; Nature. 2020 Apr 22.
- Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.; Immunity; Vol 52(1). 2020 Jan 14.
- B cell targeted therapies in autoimmune disease.; Current opinion in immunology; Vol 61. 2019 Dec.
- Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis.; Science translational medicine; Vol 11(519). 2019 Nov 20.
- PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.; JCI insight; Vol 4(20). 2019 Oct 17.
- Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis.; Nature immunology; Vol 20(10). 2019 Oct.
- Transitional B cells in quiescent SLE: An early checkpoint imprinted by IFN.; Journal of autoimmunity; Vol 102. 2019 Aug.
- The immune cell landscape in kidneys of patients with lupus nephritis.; Nature immunology; Vol 20(7). 2019 Jul.
- Bone marrow mesenchymal stem cells from patients with SLE maintain an interferon signature during in vitro culture.; Cytokine. 2019 May 29.
- Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.; Nature immunology. 2019 May 06.
- Failure of B Cell Tolerance in CVID.; Frontiers in immunology; Vol 10. 2019.
- B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.; Nature communications; Vol 9(1). 2018 Dec 03.
- Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue; Arthritis research & therapy; Vol 20(1). 2018 Jul 11.
- Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.; JCI insight; Vol 3(5). 2018 Mar 08.
- Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.; Immunity; Vol 49(4). 2018 Jan 16.
- Neutrophils Slow Disease Progression in Murine Lupus via Modulation of Autoreactive Germinal Centers.; Journal of immunology (Baltimore, Md. : 1950). 2017 Jun 05.
- Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis.; Arthritis & rheumatology (Hoboken, N.J.); Vol 68(4). 2016 Apr.
- Inhibition of G protein βγ subunit signaling abrogates nephritis in lupus prone mice.; Arthritis & rheumatology (Hoboken, N.J.). 2016 Mar 18.
- New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome.; Current opinion in rheumatology; Vol 27(5). 2015 Sep.
- Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response.; PloS one; Vol 10(6). 2015.
- NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.; The Journal of clinical investigation; Vol 124(7). 2014 Jul.
- Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche.; Journal of immunology (Baltimore, Md. : 1950); Vol 192(7). 2014 Apr 1.