Publications
Publications
- MTOR maintains endothelial cell integrity to limit lung vascular injury.; The Journal of biological chemistry. 2024 Nov 05.
- Occludin Is Essential to Maintain Normal Alveolar Barrier Integrity and Its Protective Role During ARDS Progression.; International journal of molecular sciences; Vol 25(21). 2024 Oct 29.
- Identifying novel data-driven subgroups in congenital heart disease using multi-modal measures of brain structure.; NeuroImage; Vol 297, pp. 120721. 2024 Jul 04.
- Spleen Tyrosine Kinase phosphorylates VE-cadherin to cause endothelial barrier disruption in acute lung injury.; The Journal of biological chemistry; Vol 299(12), pp. 105408. 2023 Oct 28.
- Impact of Peptide Sequence on Functional siRNA Delivery and Gene Knockdown with Cyclic Amphipathic Peptide Delivery Agents.; Molecular pharmaceutics. 2023 Jan 14.
- Management of postoperative cervical pseudomeningocele with percutaneous aspiration and epidural blood patch.; Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. 2022 Jul 11.
- Therapeutic Targeting of NF-κB in Acute Lung Injury: A Double-Edged Sword.; Cells; Vol 11(20). 2022 Jan 21.
- Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption.; Biomedicines; Vol 9(12). 2021 Dec 07.
- Phosphodiesterase 10A Is a Key Mediator of Lung Inflammation.; Journal of immunology (Baltimore, Md. : 1950). 2021 Jun 11.
- Autophagy protein ATG7 is a critical regulator of endothelial cell inflammation and permeability.; Scientific reports; Vol 10(1). 2020 Aug 13.
- Critical Role of Mortalin/GRP75 In Endothelial Cell Dysfunction Associated With Acute Lung Injury.; Shock (Augusta, Ga.). 2019 Sep 04.
- The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.; European heart journal; Vol 40(29). 2019 Aug 01.
- RNAi therapeutic strategies for acute respiratory distress syndrome.; Translational research : the journal of laboratory and clinical medicine. 2019 Jul 27.
- Critical role of autophagy regulator Beclin1 in endothelial cell inflammation and barrier disruption.; Cellular signalling. 2019 May 01.
- Selective Inactivation of Intracellular BiP/GRP78 Attenuates Endothelial Inflammation and Permeability in Acute Lung Injury.; Scientific reports; Vol 9(1). 2019 Feb 14.
- SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4.; Proceedings of the National Academy of Sciences of the United States of America; Vol 116(2). 2019 Jan 08.
- Importins α and β signaling mediates endothelial cell inflammation and barrier disruption.; Cellular signalling. 2018 Jan 10.
- Autophagy Inhibitor 3-Methyladenine Protects against Endothelial Cell Barrier Dysfunction in Acute Lung Injury.; American journal of physiology. Lung cellular and molecular physiology. 2017 Oct 26.
- Inhibition of RPTOR Prevents Hyperoxia-induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.; American journal of respiratory cell and molecular biology. 2016 Jul 2.
- Phospholipase C Epsilon Signaling Mediates Endothelial Cell Inflammation and Barrier Disruption in Acute Lung Injury.; American journal of physiology. Lung cellular and molecular physiology. 2016 Jul 1.
- Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2016 Apr 8.
- Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation. FASEB J. 30:2615-26; . 2016 Jan 01.
- Airway epithelial cell PPARγ modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(3). 2015 Aug 1.
- Regulation of endothelial cell inflammation and lung polymorphonuclear lymphocyte infiltration by transglutaminase 2.; Shock (Augusta, Ga.); Vol 42(6). 2014 Dec.
- Thrombin selectively engages LIM kinase 1 and slingshot-1L phosphatase to regulate NF-κB activation and endothelial cell inflammation.; American journal of physiology. Lung cellular and molecular physiology; Vol 305(9). 2013 Nov 1.
- Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration.; PloS one; Vol 8(3). 2013.
- Regulation of Rela/p65 and endothelial cell inflammation by proline-rich tyrosine kinase 2.; American journal of respiratory cell and molecular biology; Vol 47(5). 2012 Nov.
- GPR56 Regulates VEGF production and angiogenesis during melanoma progression.; Cancer research; Vol 71(16). 2011 Aug 15.
- Blocking NF-?B: An Inflammatory Issue.; Proc Am Thorac Soc 8:497-503. 2011 Jan 01.
- Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.; The Journal of biological chemistry; Vol 284(31). 2009 Jul 31.
- Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.; The Journal of biological chemistry; Vol 284(7). 2009 Feb 13.
- Hug tightly and say goodbye: Role of endothelial ICAM-1 in leukocyte transmigration.; Antioxid Redox Signal 11:823-829. 2009 Jan 01.
- VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 22(7). 2008 Jul.
- Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.; The Journal of biological chemistry; Vol 283(21). 2008 May 23.
- Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing.; Circulation research; Vol 101(1). 2007 Jul 6.
- Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells.; The Journal of biological chemistry; Vol 282(6). 2007 Feb 9.
- c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 292(2). 2007 Feb.
- Regulation of lung neutrophil recruitment by VE-cadherin.; American journal of physiology. Lung cellular and molecular physiology; Vol 291(4). 2006 Oct.
- p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L).; Free radical biology & medicine; Vol 41(4). 2006 Aug 15.
- Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells.; The Journal of biological chemistry; Vol 281(23). 2006 Jun 9.
- Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 174(9). 2005 May 1.
- RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65.; Journal of immunology (Baltimore, Md. : 1950); Vol 173(11). 2004 Dec 1.
- cAMP targeting of p38 MAP kinase inhibits thrombin-induced NF-kappaB activation and ICAM-1 expression in endothelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 287(5). 2004 Nov.
- E. coli pneumonia induces CD18-independent airway neutrophil migration in the absence of increased lung vascular permeability.; American journal of physiology. Lung cellular and molecular physiology; Vol 285(4). 2003 Oct.
- Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells.; The Journal of biological chemistry; Vol 278(39). 2003 Sep 26.
- Activation of protein kinase C delta by all-trans-retinoic acid.; The Journal of biological chemistry; Vol 278(35). 2003 Aug 29.
- Activation of protein kinase C delta by IFN-gamma.; Journal of immunology (Baltimore, Md. : 1950); Vol 171(1). 2003 Jul 1.
- Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1.; Circulation research; Vol 92(10). 2003 May 30.
- Inhibition of activator protein-1 transcription factor activation by omega-3 fatty acid modulation of mitogen-activated protein kinase signaling kinases.; JPEN. Journal of parenteral and enteral nutrition; Vol 27(3). 2003 May.
- Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells.; Circulation research; Vol 91(5). 2002 Sep 6.
- Nitric oxide stimulates macrophage inflammatory protein-2 expression in sepsis.; Journal of immunology (Baltimore, Md. : 1950); Vol 169(4). 2002 Aug 15.
- PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells.; Circulation research; Vol 90(9). 2002 May 17.
- Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.; The Journal of biological chemistry; Vol 277(17). 2002 Apr 26.
- Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice.; Journal of immunology (Baltimore, Md. : 1950); Vol 168(8). 2002 Apr 15.
- Time-dependent reversal of sepsis-induced PMN uptake and lung vascular injury by expression of CD18 antagonist.; American journal of physiology. Lung cellular and molecular physiology; Vol 282(4). 2002 Apr.
- Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells.; The Journal of biological chemistry; Vol 277(5). 2002 Feb 1.
- Differential role of CD18 integrins in mediating lung neutrophil sequestration and increased microvascular permeability induced by Escherichia coli in mice.; Journal of immunology (Baltimore, Md. : 1950); Vol 167(5). 2001 Sep 1.
- Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase.; Molecular and cellular biology; Vol 21(16). 2001 Aug.
- Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function.; The Journal of biological chemistry; Vol 276(25). 2001 Jun 22.
- G alpha 16 couples chemoattractant receptors to NF-kappa B activation.; Journal of immunology (Baltimore, Md. : 1950); Vol 166(11). 2001 Jun 1.
- Decreased oxidant buffering impairs NF-kappaB activation and ICAM-1 transcription in endothelial cells.; Shock (Augusta, Ga.); Vol 15(1). 2001 Jan.
- Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells.; American journal of physiology. Cell physiology; Vol 279(4). 2000 Oct.
- beta(2)-Integrin blockade driven by E-selectin promoter prevents neutrophil sequestration and lung injury in mice.; Circulation research; Vol 87(3). 2000 Aug 4.
- Activation of NF-kB induced by H2O2 and TNFa in endothelial cells and effect on ICAM-1 expression.; Am. J. Physiol: Lung Mol. Cell. Physiolol.; Vol 279, pp. 302-311. 2000 Jan 01.
- Neutrophil inhibitory factor abrogates neutrophil adhesion by blockade of CD11a and CD11b beta(2) integrins.; Molecular pharmacology; Vol 56(5). 1999 Nov.
- Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion.; Journal of immunology (Baltimore, Md. : 1950); Vol 162(9). 1999 May 1.
- Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription.; Molecular pharmacology; Vol 55(3). 1999 Mar.
- E-selectin expression in human endothelial cells by TNFa-induced oxidant generation and NF-kB activation.; Am. J. Physiol.; Vol 19, pp. 533-544. 1998 Jan 01.
- H2O2 and tumor necrosis factor-alpha activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter.; The Journal of biological chemistry; Vol 270(32). 1995 Aug 11.
- Effect of single-base substitutions in the central domain of virus-associated RNA I on its function.; Journal of virology; Vol 69(7). 1995 Jul.
- Generation of superoxide anion and hydroxyl radical by methylglyoxal.; Med. Sci. Res.; Vol 22, pp. 21-24. 1994 Jan 01.
- Activities of flavonoids for the cleavage of DNA in the presence of Cu(II): correlation with generation of active oxygen species.; Carcinogenesis; Vol 13(4). 1992 Apr.
- Strand scission in DNA induced by dietary flavonoids: role of Cu(I) and oxygen free radicals and biological consequences of scission.; Molecular and cellular biochemistry; Vol 111(1-2). 1992 Apr.
- Reaction of furfural and methylfurfural with DNA: use of single-strand-specific nucleases.; Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association; Vol 29(10). 1991 Oct.
- Anticancer drugs and DNA degradation.; Med Sci Res; Vol 19, pp. 627-631. 1991 Jan 01.
- Strand scission in DNA by quercetin and Cu(II): identification of free radical intermediates and biological consequences of scission.; Carcinogenesis; Vol 11(11). 1990 Nov.
- Complexes involving quercetin, DNA and Cu(II).; Carcinogenesis; Vol 11(11). 1990 Nov.
- Specificity of the in vitro interaction of methylfurfural with DNA.; Mutagenesis; Vol 5(2). 1990 Mar.
- Formation of strand breaks and interstrand cross-links in DNA by methylglyoxal.; Journal of biochemical toxicology; Vol 5(3). 1990.
- Strand scission in DNA induced by quercetin and Cu(II): role of Cu(I) and oxygen free radicals.; Carcinogenesis; Vol 10(10). 1989 Oct.
- Specificity of the interaction of furfural with DNA.; Mutation research; Vol 225(3). 1989 Mar.
- Dietary mutagens and carcinogens; J Sc Ind Res; Vol 46, pp. 54-60. 1987 Jan 01.
- Effect of alkylation with streptozotocin on the secondary structure of DNA.; Biosc. Rep.; Vol 6, pp. 557-564. 1986 Jan 01.