Publications
Publications
- PPARγ drives mitochondrial stress signaling and the loss of atrial cardiomyocytes in newborn mice exposed to hyperoxia.; Redox biology; Vol 76, pp. 103351. 2024 Sep 12.
- Diacetyl Inhalation Impairs Airway Epithelial Repair in Mice Infected with Influenza A Virus.; American journal of physiology. Lung cellular and molecular physiology. 2022 Sep 06.
- Ataxia telangiectasia mutated is required for efficient proximal airway epithelial cell regeneration following influenza A virus infection.; American journal of physiology. Lung cellular and molecular physiology. 2022 Feb 23.
- Neonatal Hyperoxia Activates ATF4 to Stimulate Folate Metabolism and AT2 Cell Proliferation.; American journal of respiratory cell and molecular biology. 2022 Jan 19.
- Low Dose Hyperoxia Primes Airways for Fibrosis in Mice after Influenza A Infection.; American journal of physiology. Lung cellular and molecular physiology. 2021 Jul 29.
- Neonatal hyperoxia impairs adipogenesis of bone marrow-derived mesenchymal stem cells and fat accumulation in adult mice.; Free radical biology & medicine. 2021 Mar 20.
- Neonatal hyperoxia inhibits proliferation and survival of atrial cardiomyocytes by suppressing fatty acid synthesis.; JCI insight. 2021 Jan 28.
- Lung SOD3 limits neurovascular reperfusion injury and systemic immune activation following transient global cerebral ischemia.; Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association; Vol 29(9). 2020 Sep.
- Early Neonatal Oxygen Exposure Predicts Pulmonary Morbidity and Functional Deficits at 1 Year.; The Journal of pediatrics; Vol 223. 2020 Aug.
- TNF Induces Obliterative Pulmonary Vascular Disease in a Novel Model of Connective Tissue Disease Associated Pulmonary Arterial Hypertension (CTD-PAH).; Arthritis & rheumatology (Hoboken, N.J.). 2020 May 10.
- Neonatal hyperoxia enhances age-dependent expression of SARS-CoV-2 receptors in mice.; Scientific reports; Vol 10(1). 2020 Jan 28.
- Pulmonary mechanics and structural lung development after neonatal hyperoxia in mice.; Pediatric research. 2019 Dec 13.
- Swapping mitochondria: A key to understanding susceptibility to neonatal chronic lung disease.; American journal of physiology. Lung cellular and molecular physiology. 2019 Oct 09.
- Ataxia-telangiectasia mutated is required for the development of protective immune memory after influenza A virus infection.; American journal of physiology. Lung cellular and molecular physiology. 2019 Sep 11.
- Lung-Derived SOD3 Attenuates Neurovascular Injury After Transient Global Cerebral Ischemia.; Journal of the American Heart Association; Vol 8(9). 2019 May 07.
- An Elusive Fox that Suppresses Scgb1a1 in Asthma Has Been Found.; American journal of respiratory cell and molecular biology. 2019 Feb 06.
- Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles.; Neurotoxicology and teratology. 2018 Oct 11.
- Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice.; Neurotoxicology. 2018 Jun 16.
- Neonatal hyperoxia depletes pulmonary vein cardiomyocytes in adult mice via mitochondrial oxidation.; American journal of physiology. Lung cellular and molecular physiology. 2018 Jan 18.
- Lung-Specific Extracellular Superoxide Dismutase Improves Cognition of Adult Mice Exposed to Neonatal Hyperoxia.; Frontiers in medicine; Vol 5. 2018.
- Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia.; PloS one; Vol 13(12). 2018.
- Oxygen-dependent changes in lung development do not affect epithelial infection with influenza A virus.; American journal of physiology. Lung cellular and molecular physiology. 2017 Aug 10.
- SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia.; Experimental lung research. 2017 Jul 27.
- Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.; American journal of respiratory cell and molecular biology; Vol 56(4). 2017 Apr.
- Giving New Identities to Alveolar Epithelial Type I Cells.; American journal of respiratory cell and molecular biology; Vol 56(3). 2017 Mar.
- The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung.; Stem cells (Dayton, Ohio); Vol 34(5). 2016 May.
- Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction.; Redox biology; Vol 5. 2015 Aug.
- Neonatal hyperoxia leads to persistent alterations in NK responses to influenza A virus infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 308(1). 2015 Jan 1.
- Bronchopulmonary dysplasia early changes leading to long-term consequences.; Frontiers in medicine; Vol 2. 2015.
- Affect of Early Life Oxygen Exposure on Proper Lung Development and Response to Respiratory Viral Infections.; Frontiers in medicine; Vol 2. 2015.
- DNA double-strand breaks activate ATM independent of mitochondrial dysfunction in A549 cells.; Free radical biology & medicine; Vol 75. 2014 Oct.
- The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator.; American journal of physiology. Lung cellular and molecular physiology; Vol 307(7). 2014 Oct 01.
- Cumulative neonatal oxygen exposure predicts response of adult mice infected with influenza A virus.; Pediatric pulmonology. 2014 May 22.
- Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells.; American journal of respiratory cell and molecular biology; Vol 50(4). 2014 Apr.
- Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis.; Journal of immunology (Baltimore, Md. : 1950); Vol 191(9). 2013 Nov 1.
- Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling.; American journal of physiology. Lung cellular and molecular physiology; Vol 305(6). 2013 Sep 15.
- Neonatal hyperoxia alters the host response to influenza A virus infection in adult mice through multiple pathways.; American journal of physiology. Lung cellular and molecular physiology; Vol 305(4). 2013 Aug 15.
- Neonatal hyperoxia increases sensitivity of adult mice to bleomycin-induced lung fibrosis.; American journal of respiratory cell and molecular biology; Vol 48(2). 2013 Feb.
- Angiotensin II: tapping the cell cycle machinery to kill endothelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 303(7). 2012 Oct 1.
- Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation.; Clinical and vaccine immunology : CVI; Vol 19(9). 2012 Sep.
- Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1.; The American journal of pathology; Vol 181(2). 2012 Aug.
- Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice.; American journal of physiology. Lung cellular and molecular physiology; Vol 302(10). 2012 May 15.
- Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice.; American journal of respiratory cell and molecular biology; Vol 45(3). 2011 Sep.
- The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA.; Cell cycle (Georgetown, Tex.); Vol 10(15). 2011 Aug 01.
- Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice.; The American journal of pathology; Vol 178(6). 2011 Jun.
- Bcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell death.; Experimental lung research; Vol 37(2). 2011 Mar.
- Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development.; American journal of respiratory cell and molecular biology; Vol 43(3). 2010 Sep.
- Murine mechanical ventilation stimulates alveolar epithelial cell proliferation.; Experimental lung research; Vol 36(6). 2010 Aug.
- Hyperoxia augments ER-stress-induced cell death independent of BiP loss.; Free radical biology & medicine; Vol 47(12). 2009 Dec 15.
- Neonatal oxygen adversely affects lung function in adult mice without altering surfactant composition or activity.; American journal of physiology. Lung cellular and molecular physiology; Vol 297(4). 2009 Oct.
- Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 111(1). 2009 Sep.
- Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 296(4). 2009 Apr.
- p21(Cip1) protects against oxidative stress by suppressing ER-dependent activation of mitochondrial death pathways.; Free radical biology & medicine; Vol 46(1). 2009 Jan 1.
- Parenchymal cell TNF receptors contribute to inflammatory cell recruitment and respiratory failure in Pneumocystis carinii-induced pneumonia.; Journal of immunology (Baltimore, Md. : 1950); Vol 181(2). 2008 Jul 15.
- hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.; Oncogene; Vol 27(29). 2008 Jul 3.
- Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.; American journal of respiratory cell and molecular biology; Vol 39(1). 2008 Jul.
- Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus.; American journal of respiratory and critical care medicine; Vol 177(10). 2008 May 15.
- PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of bax death.; Free radical biology & medicine; Vol 44(3). 2008 Feb 1.
- Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 292(3). 2007 Mar.
- c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 292(2). 2007 Feb.
- Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development.; American journal of physiology. Lung cellular and molecular physiology; Vol 291(5). 2006 Nov.
- p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L).; Free radical biology & medicine; Vol 41(4). 2006 Aug 15.
- p21Cip1 protection against hyperoxia requires Bcl-XL and is uncoupled from its ability to suppress growth.; The American journal of pathology; Vol 168(6). 2006 Jun.
- Transgenic extracellular superoxide dismutase protects postnatal alveolar epithelial proliferation and development during hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 290(1). 2006 Jan.
- Hyperoxic ventilated premature baboons have increased p53, oxidant DNA damage and decreased VEGF expression.; Pediatric research; Vol 58(3). 2005 Sep.
- Reactive oxidant and p42/44 MAP kinase signaling is necessary for mechanical strain-induced proliferation in pulmonary epithelial cells.; Journal of applied physiology (Bethesda, Md. : 1985); Vol 99(3). 2005 Sep.
- High mobility group A2 potentiates genotoxic stress in part through the modulation of basal and DNA damage-dependent phosphatidylinositol 3-kinase-related protein kinase activation.; Cancer research; Vol 65(15). 2005 Aug 1.
- Acute tumor necrosis factor-alpha-induced liver injury in the absence of tumor necrosis factor receptor-associated factor 1 gene expression.; The American journal of pathology; Vol 166(6). 2005 Jun.
- p21(Cip1/WAF1/Sdi1) does not affect expression of base excision DNA repair enzymes during chronic oxidative stress.; Antioxidants & redox signaling; Vol 7(5-6). 2005 May.
- Loss of Gadd45a does not modify the pulmonary response to oxidative stress.; American journal of physiology. Lung cellular and molecular physiology; Vol 288(4). 2005 Apr.
- p53 modulates radiation sensitivity independent of p21 transcriptional activation.; American journal of clinical oncology; Vol 28(1). 2005 Feb.
- Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.; The Journal of biological chemistry; Vol 280(2). 2005 Jan 14.
- Macroarray analysis reveals a strain-induced oxidant response in pulmonary epithelial cells.; Experimental lung research; Vol 30(8). 2004 Dec.
- In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 286(5). 2004 May.
- DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway.; The EMBO journal; Vol 23(5). 2004 Mar 10.
- The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 286(3). 2004 Mar.
- Effects of hyperoxia on tumor necrosis factor alpha and Grobeta expression in newborn rabbit lungs.; Lung; Vol 181(6). 2003 Nov.
- Induced p21Cip1 in premature baboons with CLD: implications for alveolar hypoplasia.; American journal of physiology. Lung cellular and molecular physiology; Vol 285(4). 2003 Oct.
- Identification and isolation of mouse type II cells on the basis of intrinsic expression of enhanced green fluorescent protein.; American journal of physiology. Lung cellular and molecular physiology; Vol 285(3). 2003 Sep.
- Activation of the G2 cell cycle checkpoint enhances survival of epithelial cells exposed to hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 284(2). 2003 Feb.
- Carbonic anhydrase XII mRNA encodes a hydratase that is differentially expressed along the rabbit nephron.; American journal of physiology. Renal physiology; Vol 284(2). 2003 Feb.
- Increased epithelial cell proliferation in very premature baboons with chronic lung disease.; American journal of physiology. Lung cellular and molecular physiology; Vol 283(5). 2002 Nov.
- Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1).; The American journal of pathology; Vol 161(4). 2002 Oct.
- Growth arrest in G1 protects against oxygen-induced DNA damage and cell death.; Journal of cellular physiology; Vol 193(1). 2002 Oct.
- p53-dependent induction of p21(Cip1/WAF1/Sdi1) protects against oxygen-induced toxicity.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 63(2). 2001 Oct.
- The cyclin-dependent kinase inhibitor p21 protects the lung from oxidative stress.; American journal of respiratory cell and molecular biology; Vol 24(6). 2001 Jun.
- The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 280(4). 2001 Apr.
- Bcl-2 family gene expression during severe hyperoxia induced lung injury.; Laboratory investigation; a journal of technical methods and pathology; Vol 80(12). 2000 Dec.
- Pulmonary chemokine and mutagenic responses in rats after subchronic inhalation of amorphous and crystalline silica.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 56(2). 2000 Aug.
- p53-independent induction of GADD45 and GADD153 in mouse lungs exposed to hyperoxia.; American journal of physiology. Lung cellular and molecular physiology; Vol 278(3). 2000 Mar.
- Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2.; American journal of respiratory cell and molecular biology; Vol 22(2). 2000 Feb.
- Hyperoxia inhibits proliferation of Mv1Lu epithelial cells independent of TGF-beta signaling.; The American journal of physiology; Vol 277(6 Pt 1). 1999 Dec.
- Accumulation of p21(Cip1/WAF1) during hyperoxic lung injury in mice.; American journal of respiratory cell and molecular biology; Vol 19(5). 1998 Nov.
- TGF-beta1 up-regulates the mRNA for the Na+/Ca2+ exchanger in neonatal rat cardiac myocytes.; Cellular and molecular biology (Noisy-le-Grand, France); Vol 44(3). 1998 May.
- Exposure to hyperoxia induces p53 expression in mouse lung epithelium.; American journal of respiratory cell and molecular biology; Vol 18(1). 1998 Jan.
- Temporal changes in expression of TGF-beta isoforms in mouse lung exposed to oxygen.; The American journal of physiology; Vol 272(1 Pt 1). 1997 Jan.
- Regulation of the transforming growth factor-beta 1 and -beta 3 promoters by transcription factor Sp1.; Gene; Vol 129(2). 1993 Jul 30.
- Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion.; Proceedings of the National Academy of Sciences of the United States of America; Vol 90(13). 1993 Jul 1.
- Identification of an activating transcription factor (ATF) binding site in the human transforming growth factor-beta 2 promoter.; The Journal of biological chemistry; Vol 267(28). 1992 Oct 5.
- Differential regulation of the transforming growth factor type-beta 2 gene promoter in embryonal carcinoma cells and their differentiated cells.; Developmental biology; Vol 153(1). 1992 Sep.