Epigenetic Gene Regulation and Human Disease

Epigenetic control of gene expression is essential for many cellular processes. Epigenetic gene regulation is essential for normal development and is an important mechanism that allows an organism to respond to their environment. Disruption of epigenetic programs can contribute to a host of issues, ranging from birth defects to cancer. The Steiner lab has a long standing interest in understanding how epigenetic regulatory mechanisms function during normal development and how disruption of these processes contributes to human disease. To that end, they have studied epigenetic control of gene regulation in the context of the neural, hematopoietic, and pulmonary systems.

Recent Publications

• Sollinger C, Lillis J, Malik J, Getman M, Proschel C, and Steiner LA. "Erythropoietin Signaling Regulates Key Epigenetic and Transcription Networks in Fetal Neural Progenitor Cells." Scientific Reports. Oct 30;7(1):14381. PMID: 29084993